ATE456568T1 - Kondensierte heterocyclische isoxazolinderivate und deren verwendung als antidepressiva - Google Patents

Kondensierte heterocyclische isoxazolinderivate und deren verwendung als antidepressiva

Info

Publication number: ATE456568T1
Authority: AT; Austria
Prior art keywords: antidepressants; condensed heterocyclic; isoxazoline derivatives; heterocyclic isoxazoline; derivatives
Prior art date: 2002-08-15

Application number

AT03792431T

Other languages

English (en)

Inventor

Jose I Andres-Gil

Manuel J Alcazar-Vaca

Jose M Bartolome-Nebreda

Francisco J Fernandez-Gadea

Margaretha Bakker

Antonius A H P Megens

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-08-15

Filing date

2003-08-13

Publication date

2010-02-15

2003-08-13 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2010-02-15 Application granted granted Critical

2010-02-15 Publication of ATE456568T1 publication Critical patent/ATE456568T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Psychiatry (AREA)
Addiction (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Child & Adolescent Psychology (AREA)
Obesity (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Gynecology & Obstetrics (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Nutrition Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT03792431T 2002-08-15 2003-08-13 Kondensierte heterocyclische isoxazolinderivate und deren verwendung als antidepressiva ATE456568T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP02078373		2002-08-15
PCT/EP2003/050377 WO2004018483A1 (en)	2002-08-15	2003-08-13	Fused heterocyclic isoxazoline derivatives and their use as anti-depressants

Publications (1)

Publication Number	Publication Date
ATE456568T1 true ATE456568T1 (de)	2010-02-15

Family

ID=31896916

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03792431T ATE456568T1 (de)	2002-08-15	2003-08-13	Kondensierte heterocyclische isoxazolinderivate und deren verwendung als antidepressiva

Country Status (13)

Country	Link
US (1)	US7501418B2 (de)
EP (1)	EP1554286B1 (de)
JP (1)	JP4478571B2 (de)
CN (1)	CN100522972C (de)
AR (1)	AR040974A1 (de)
AT (1)	ATE456568T1 (de)
AU (1)	AU2003262573B2 (de)
CA (1)	CA2494557C (de)
DE (1)	DE60331160D1 (de)
ES (1)	ES2339444T3 (de)
HK (1)	HK1080469A1 (de)
TW (1)	TW200413393A (de)
WO (1)	WO2004018483A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE602005016836D1 (de) *	2004-11-26	2009-11-05	Janssen Pharmaceutica Nv	Chotischer und anxiolytischer aktivität
EP2072512A1 (de) *	2007-12-20	2009-06-24	Bayer CropScience AG	Herbizide Verbindungen auf Basis von N-Azinyl-N'-pyridylsulfonyl-harnstoffen
BRPI0820842A2 (pt) *	2007-12-20	2014-12-23	Bayer Cropscicence Ag	Compostos herbicidas à base de n-azinil-n'-piridilsulfonil-uréias
US8765735B2 (en) *	2009-05-18	2014-07-01	Infinity Pharmaceuticals, Inc.	Isoxazolines as inhibitors of fatty acid amide hydrolase
US9149465B2 (en) *	2009-05-18	2015-10-06	Infinity Pharmaceuticals, Inc.	Isoxazolines as inhibitors of fatty acid amide hydrolase
US8927551B2 (en) *	2009-05-18	2015-01-06	Infinity Pharmaceuticals, Inc.	Isoxazolines as inhibitors of fatty acid amide hydrolase

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0361577B1 (de) *	1988-09-19	1993-05-05	Akzo N.V.	Tetrahydronaphthalin und Indan-Derivate
DE69415341T2 (de) *	1993-09-15	1999-07-15	Merck Sharp & Dohme Ltd., Hoddesdon, Hertfordshire	Kondensierte tricyclische heteroaromatische derivate als liganden des dopamin-rezeptor-subtyps
IL125197A0 (en) *	1996-01-05	1999-03-12	Hoechst Marion Roussel Inc	4,5-dihydronaphth (1,2-c) isoxazoles and derivatives thereof having cns activity
US6187774B1 (en) *	1996-03-04	2001-02-13	Yoshitomi Pharmaceutical Industries, Ltd.	Fused heterocyclic compounds and pharmaceutical applications thereof
WO1999067237A1 (en)	1998-06-19	1999-12-29	H. Lundbeck A/S	4,5,6 and 7-indole and indoline derivatives, their preparation and use
AU2002244717B2 (en) *	2001-02-21	2007-07-19	Janssen Pharmaceutica N.V.	Isoxazoline derivatives as anti-depressants

2003
- 2003-08-13 WO PCT/EP2003/050377 patent/WO2004018483A1/en active Application Filing
- 2003-08-13 AT AT03792431T patent/ATE456568T1/de not_active IP Right Cessation
- 2003-08-13 EP EP03792431A patent/EP1554286B1/de not_active Expired - Lifetime
- 2003-08-13 DE DE60331160T patent/DE60331160D1/de not_active Expired - Lifetime
- 2003-08-13 ES ES03792431T patent/ES2339444T3/es not_active Expired - Lifetime
- 2003-08-13 CA CA2494557A patent/CA2494557C/en not_active Expired - Fee Related
- 2003-08-13 AU AU2003262573A patent/AU2003262573B2/en not_active Ceased
- 2003-08-13 US US10/524,123 patent/US7501418B2/en not_active Expired - Lifetime
- 2003-08-13 JP JP2004530272A patent/JP4478571B2/ja not_active Expired - Fee Related
- 2003-08-13 CN CNB038194627A patent/CN100522972C/zh not_active Expired - Fee Related
- 2003-08-14 TW TW092122311A patent/TW200413393A/zh unknown
- 2003-08-14 AR ARP030102945A patent/AR040974A1/es not_active Application Discontinuation
2006
- 2006-01-06 HK HK06100287.6A patent/HK1080469A1/zh unknown

Also Published As

Publication number	Publication date
DE60331160D1 (de)	2010-03-18
WO2004018483A1 (en)	2004-03-04
CA2494557A1 (en)	2004-03-04
TW200413393A (en)	2004-08-01
AU2003262573A1 (en)	2004-03-11
CN100522972C (zh)	2009-08-05
HK1080469A1 (zh)	2006-04-28
US20060116378A1 (en)	2006-06-01
EP1554286B1 (de)	2010-01-27
JP2005538144A (ja)	2005-12-15
JP4478571B2 (ja)	2010-06-09
AU2003262573B2 (en)	2009-04-23
CA2494557C (en)	2011-10-18
ES2339444T3 (es)	2010-05-20
US7501418B2 (en)	2009-03-10
AR040974A1 (es)	2005-04-27
CN1675224A (zh)	2005-09-28
EP1554286A1 (de)	2005-07-20

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ATE459605T1 (de)	2010-03-15	Isoxazolinderivate und deren verwendung als herbizide
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Legal Events

Date	Code	Title	Description
2010-07-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties