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ATE455862T1 - Verbesserter rezeptornachweis - Google Patents

Verbesserter rezeptornachweis

Info

Publication number
ATE455862T1
ATE455862T1 AT03756374T AT03756374T ATE455862T1 AT E455862 T1 ATE455862 T1 AT E455862T1 AT 03756374 T AT03756374 T AT 03756374T AT 03756374 T AT03756374 T AT 03756374T AT E455862 T1 ATE455862 T1 AT E455862T1
Authority
AT
Austria
Prior art keywords
enzyme
fragment
binding
galactosidase
conjugated
Prior art date
Application number
AT03756374T
Other languages
English (en)
Inventor
Tabassum Naqvi
Riaz Rouhani
Rajendra Singh
Original Assignee
Discoverx Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Discoverx Corp filed Critical Discoverx Corp
Application granted granted Critical
Publication of ATE455862T1 publication Critical patent/ATE455862T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
  • Prostheses (AREA)
  • Glass Compositions (AREA)
  • Paints Or Removers (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT03756374T 2002-05-29 2003-05-29 Verbesserter rezeptornachweis ATE455862T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38406002P 2002-05-29 2002-05-29
PCT/US2003/017428 WO2003102154A2 (en) 2002-05-29 2003-05-29 Improved receptor detection

Publications (1)

Publication Number Publication Date
ATE455862T1 true ATE455862T1 (de) 2010-02-15

Family

ID=29711971

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03756374T ATE455862T1 (de) 2002-05-29 2003-05-29 Verbesserter rezeptornachweis

Country Status (8)

Country Link
US (1) US20040018562A1 (de)
EP (1) EP1507869B1 (de)
JP (1) JP2005527239A (de)
AT (1) ATE455862T1 (de)
AU (1) AU2003243375A1 (de)
CA (1) CA2487513A1 (de)
DE (1) DE60331059D1 (de)
WO (1) WO2003102154A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7402397B2 (en) 2002-05-21 2008-07-22 Monogram Biosciences, Inc. Detecting and profiling molecular complexes
US20040229294A1 (en) * 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB surface receptor complexes as biomarkers
US20040229380A1 (en) * 2002-05-21 2004-11-18 Po-Ying Chan-Hui ErbB heterodimers as biomarkers
JP2006503582A (ja) * 2002-10-21 2006-02-02 ディスカヴァーエックス インコーポレイテッド Ip3タンパク質結合測定法
EP1681983A4 (de) * 2003-10-14 2008-12-10 Monogram Biosciences Inc Rezeptor-tyrosin-kinase-signalpfad-analyse für diagnose und therapie
US20050136488A1 (en) * 2003-11-06 2005-06-23 Horecka Joseph L. Cellular membrane protein assay
US7608415B2 (en) * 2004-06-30 2009-10-27 Discoverx Corporation Analysis of intracellular modifications
AU2006306344A1 (en) * 2005-10-24 2007-05-03 Discoverx Corporation Detection of intracellular enzyme complex

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708929A (en) * 1984-10-29 1987-11-24 Microgenics Corporation Methods for protein binding enzyme complementation assays
US5223393A (en) * 1990-06-12 1993-06-29 Microgenics Corporation Detection of analytes having binding sites for at least two binding moieties
US5976857A (en) * 1996-01-26 1999-11-02 Boehringer Mannheim Corporation Cross-linked polypeptide fragments of β-galactosidase
ATE387506T1 (de) * 2001-05-09 2008-03-15 Discoverx Inc Screening auf enzyminhibitoren
AU2003231060A1 (en) * 2002-05-02 2003-11-17 Discoverx, Inc. Short enzyme donor fragment

Also Published As

Publication number Publication date
EP1507869A4 (de) 2006-10-25
DE60331059D1 (de) 2010-03-11
WO2003102154A3 (en) 2004-05-06
CA2487513A1 (en) 2003-12-11
EP1507869A2 (de) 2005-02-23
US20040018562A1 (en) 2004-01-29
EP1507869B1 (de) 2010-01-20
AU2003243375A8 (en) 2003-12-19
AU2003243375A1 (en) 2003-12-19
JP2005527239A (ja) 2005-09-15
WO2003102154A2 (en) 2003-12-11

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Legal Events

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