ATE449640T1 - Verfahren zur herstellung einer teildurchlässigen nicht thrombogene membran - Google Patents
Verfahren zur herstellung einer teildurchlässigen nicht thrombogene membranInfo
- Publication number
- ATE449640T1 ATE449640T1 AT01903969T AT01903969T ATE449640T1 AT E449640 T1 ATE449640 T1 AT E449640T1 AT 01903969 T AT01903969 T AT 01903969T AT 01903969 T AT01903969 T AT 01903969T AT E449640 T1 ATE449640 T1 AT E449640T1
- Authority
- AT
- Austria
- Prior art keywords
- membrane
- thrombogenic
- plasma
- producing
- support
- Prior art date
Links
- 239000012528 membrane Substances 0.000 title abstract 6
- 230000001453 nonthrombogenic effect Effects 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008280 blood Substances 0.000 abstract 3
- 210000004369 blood Anatomy 0.000 abstract 3
- 125000000129 anionic group Chemical group 0.000 abstract 2
- 239000003146 anticoagulant agent Substances 0.000 abstract 2
- 229940127219 anticoagulant drug Drugs 0.000 abstract 2
- 229920006317 cationic polymer Polymers 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
- B01D67/0081—After-treatment of organic or inorganic membranes
- B01D67/0093—Chemical modification
- B01D67/00931—Chemical modification by introduction of specific groups after membrane formation, e.g. by grafting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
- A61L33/0005—Use of materials characterised by their function or physical properties
- A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
- B01D63/02—Hollow fibre modules
- B01D63/021—Manufacturing thereof
- B01D63/0233—Manufacturing thereof forming the bundle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
- B01D65/02—Membrane cleaning or sterilisation ; Membrane regeneration
- B01D65/022—Membrane sterilisation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/06—Organic material
- B01D71/40—Polymers of unsaturated acids or derivatives thereof, e.g. salts, amides, imides, nitriles, anhydrides, esters
- B01D71/42—Polymers of nitriles, e.g. polyacrylonitrile
- B01D71/421—Polyacrylonitrile
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/16—Use of chemical agents
- B01D2321/168—Use of other chemical agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
- B01D2321/34—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling by radiation
- B01D2321/346—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling by radiation by gamma radiation
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Materials Engineering (AREA)
- Transplantation (AREA)
- Surgery (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0001065A FR2804328B1 (fr) | 2000-01-27 | 2000-01-27 | Membrane semi-permeable non thrombogene et procede de fabrication |
PCT/FR2001/000248 WO2001054802A1 (fr) | 2000-01-27 | 2001-01-26 | Membrane semi-permeable non thrombogene et procede de fabrication |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE449640T1 true ATE449640T1 (de) | 2009-12-15 |
Family
ID=8846384
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01903969T ATE449640T1 (de) | 2000-01-27 | 2001-01-26 | Verfahren zur herstellung einer teildurchlässigen nicht thrombogene membran |
Country Status (10)
Country | Link |
---|---|
US (1) | US7056458B2 (de) |
EP (1) | EP1165214B1 (de) |
JP (1) | JP4234345B2 (de) |
AT (1) | ATE449640T1 (de) |
AU (1) | AU779469B2 (de) |
CA (1) | CA2368999C (de) |
DE (1) | DE60140588D1 (de) |
ES (1) | ES2337231T3 (de) |
FR (1) | FR2804328B1 (de) |
WO (1) | WO2001054802A1 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2859114B1 (fr) * | 2003-08-28 | 2005-10-14 | Gambro Lundia Ab | Dispositif de filtration comportant une membrane semi-permeable pour le traitement extracorporel du sang ou du plasma pour prevenir notamment l'activation retardee de la phase contact |
US20050045554A1 (en) | 2003-08-28 | 2005-03-03 | Gambro Lundia Ab | Membrane unit element, semipermeable membrane, filtration device, and processes for manufacturing the same |
US20100239673A1 (en) * | 2005-08-01 | 2010-09-23 | Linhardt Robert J | Blood compatible nanomaterials and methods of making and using the same |
FR2902670B1 (fr) | 2006-06-22 | 2009-04-24 | Gambro Lundia Ab | Utilisation d'une suspension pour traiter un support a usage medical, support a usage medical, echangeur et dispositif d'adsorption comprenant le support |
DE102006044525B3 (de) * | 2006-09-21 | 2008-01-31 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Herstellung von gemeinsam bereitstellbaren flexiblen integrierten Schaltkreisen |
JP5266856B2 (ja) * | 2008-04-22 | 2013-08-21 | 富士ゼロックス株式会社 | 難燃剤、樹脂組成物、及び樹脂成形体 |
EP2177603A1 (de) | 2008-09-25 | 2010-04-21 | Gambro Lundia AB | Vorrichtung für Nierenzellexpansion |
EP2168666A1 (de) | 2008-09-25 | 2010-03-31 | Gambro Lundia AB | Bestrahlte Membran für Zellexpansion |
EP2168614B1 (de) | 2008-09-25 | 2012-02-15 | Gambro Lundia AB | Hybride biologische künstliche Niere |
EP2168668A1 (de) | 2008-09-25 | 2010-03-31 | Gambro Lundia AB | Membran für Zellexpansion |
DK2295132T3 (en) * | 2009-05-15 | 2016-12-05 | Interface Biologics Inc | Antithrombogenic hollow-fiber membranes, molding material and blood long |
EP3095509A1 (de) | 2015-05-18 | 2016-11-23 | Defymed | Funktionalisierte membrane für biokünstliche organe |
EP3124099A1 (de) | 2015-07-30 | 2017-02-01 | Gambro Lundia AB | Acrylnitril-basierte membran mit verbesserter leistung |
CN105943497B (zh) * | 2016-05-11 | 2019-09-10 | 中国人民解放军第三军医大学 | 一种自组装纳米止血剂、其制备方法及应用 |
EP3296010B1 (de) | 2016-09-14 | 2023-04-26 | Gambro Lundia AB | Auf acrylonitril basierende membran mit niedriger thrombogenität |
EP3529300A4 (de) | 2016-10-18 | 2020-03-18 | Evonik Canada Inc. | Plastifizierte pvc-beigaben mit oberflächenmodifizierenden makromolekülen und daraus hergestellte artikel |
EP3548164A1 (de) | 2016-11-29 | 2019-10-09 | Gambro Lundia AB | Membran zur adsorption von bakterien |
EP3388140A1 (de) | 2017-04-10 | 2018-10-17 | Gambro Lundia AB | Extrakorporaler blutkreislauf |
EP3652229A1 (de) | 2017-07-14 | 2020-05-20 | Fresenius Medical Care Holdings, Inc. | Verfahren zur bereitstellung einer oberflächenmodifizierenden zusammensetzung mit verbesserter nebenproduktentfernung |
CN107929838B (zh) * | 2017-11-15 | 2020-12-25 | 青岛市市立医院 | 用于肾脏内科的血液透析装置 |
WO2019139085A1 (ja) * | 2018-01-10 | 2019-07-18 | テルモ株式会社 | 人工肺の製造方法 |
EP3680005A1 (de) | 2019-01-10 | 2020-07-15 | Gambro Lundia AB | Membran mit immobilisiertem anticoagulans und verfahren zu ihrer herstellung |
EP3981505A1 (de) | 2020-10-12 | 2022-04-13 | Gambro Lundia AB | Membran mit immobilisiertem antikoagulans und verfahren zu ihrer herstellung |
EP4201507A1 (de) | 2021-12-21 | 2023-06-28 | Gambro Lundia AB | Verfahren zur erhöhung der selektivität einer membran |
EP4201508A1 (de) | 2021-12-21 | 2023-06-28 | Gambro Lundia AB | Membran mit coating aus polydopamin und chondroitin sowie verfahren zu deren herstellung |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4749619A (en) * | 1985-08-21 | 1988-06-07 | Hospal Industrie | Hollow fibre useful in blood treating processes |
US4800016A (en) * | 1986-11-24 | 1989-01-24 | The University Of Michigan | Extracorporeal blood de-heparinization system |
JPS63290573A (ja) | 1987-03-13 | 1988-11-28 | バクスター・インターナショナル・インコーポレイテッド | ヘパリン緩放出用医療装置 |
DE3837298C1 (de) * | 1988-11-03 | 1990-03-29 | Fresenius Ag, 6380 Bad Homburg, De | |
US5455040A (en) * | 1990-07-26 | 1995-10-03 | Case Western Reserve University | Anticoagulant plasma polymer-modified substrate |
WO1993005825A1 (en) | 1991-09-20 | 1993-04-01 | Baxter International Inc. | Processes for reducing the thrombogenicity of biomaterials |
DE4230513C1 (de) * | 1992-09-11 | 1994-03-31 | Fresenius Ag | Vorrichtung zur Entfernung von Aluminiumionen aus Blut und Lösung zur Verwendung in der Vorrichtung |
DE4240681C2 (de) | 1992-12-03 | 1994-09-08 | Fresenius Ag | Vorrichtung zur Hämodialyse ohne Antikoagulation |
NO931809L (no) * | 1993-05-19 | 1994-11-21 | Norsk Hydro As | Hemofilter |
US5421815A (en) * | 1993-12-14 | 1995-06-06 | Nof Corporation | Method for blood dialysis using anticoagulent composition |
US5509895A (en) * | 1993-12-14 | 1996-04-23 | Nof Corporation | Air trap chamber device for blood dialysis circuit containing an anticoagulant composition |
SI9400289A (en) * | 1994-07-13 | 1996-02-29 | Ponikvar Jadranka Buturovic | A method for preventing blood coagulation in a haemodialysis circuit or haemodialysis analogy procedure in the extra-body circuit. |
US5801063A (en) | 1995-05-09 | 1998-09-01 | Grandics; Peter | Device and process for the biospecific removal of heparin |
US5820917A (en) * | 1995-06-07 | 1998-10-13 | Medtronic, Inc. | Blood-contacting medical device and method |
US5679659A (en) * | 1995-08-22 | 1997-10-21 | Medtronic, Inc. | Method for making heparinized biomaterials |
US5767108A (en) | 1995-08-22 | 1998-06-16 | Medtronic, Inc. | Method for making improved heparinized biomaterials |
US5672638A (en) * | 1995-08-22 | 1997-09-30 | Medtronic, Inc. | Biocompatability for solid surfaces |
DE19533682A1 (de) * | 1995-09-12 | 1997-03-13 | Biotronik Mess & Therapieg | Verfahren zum Anlagern und Immobilisieren von Heparin auf anorganischen Substratoberflächen von kardiovaskulären Implantanten |
EP0769503A3 (de) | 1995-10-17 | 1997-10-08 | Terumo Corp | Heparinkomplex und medizinische Anordnung die solche Verbindung enthält |
US6306165B1 (en) | 1996-09-13 | 2001-10-23 | Meadox Medicals | ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin |
US5855618A (en) | 1996-09-13 | 1999-01-05 | Meadox Medicals, Inc. | Polyurethanes grafted with polyethylene oxide chains containing covalently bonded heparin |
FR2758990B1 (fr) * | 1996-09-19 | 1999-05-28 | Hospal Ind | Appareil pour le traitement du sang par circulation extracorporelle et procede de fabrication |
US5891196A (en) | 1997-04-16 | 1999-04-06 | Baxter International Inc. | Method for actively binding heparin to crosslinked biological tissues |
EP0878491A3 (de) | 1997-05-15 | 2000-08-30 | Degussa-Hüls Aktiengesellschaft | Heparinanaloge Homo- oder Copolymere, ihre Herstellung und Verwendung |
US5885609A (en) * | 1997-05-23 | 1999-03-23 | Northeastern University | Biocompatible articles and method for making same |
ES2251090T3 (es) | 1997-05-27 | 2006-04-16 | Sanofi-Aventis | Dispositivo y metodo para aplicar articulos planos. |
FR2772639B1 (fr) * | 1997-12-24 | 2000-02-04 | Hospal Ind | Utilisation d'un polymere neutre ou cationique pour prevenir l'activation de la phase contact du sang ou du plasma en contact avec une membrane semi-permeable |
-
2000
- 2000-01-27 FR FR0001065A patent/FR2804328B1/fr not_active Expired - Lifetime
-
2001
- 2001-01-26 AT AT01903969T patent/ATE449640T1/de not_active IP Right Cessation
- 2001-01-26 EP EP01903969A patent/EP1165214B1/de not_active Expired - Lifetime
- 2001-01-26 JP JP2001554779A patent/JP4234345B2/ja not_active Expired - Lifetime
- 2001-01-26 AU AU31913/01A patent/AU779469B2/en not_active Expired
- 2001-01-26 ES ES01903969T patent/ES2337231T3/es not_active Expired - Lifetime
- 2001-01-26 DE DE60140588T patent/DE60140588D1/de not_active Expired - Lifetime
- 2001-01-26 WO PCT/FR2001/000248 patent/WO2001054802A1/fr active Application Filing
- 2001-01-26 CA CA002368999A patent/CA2368999C/fr not_active Expired - Lifetime
- 2001-01-26 US US09/937,558 patent/US7056458B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU3191301A (en) | 2001-08-07 |
FR2804328B1 (fr) | 2002-03-15 |
US7056458B2 (en) | 2006-06-06 |
EP1165214A1 (de) | 2002-01-02 |
JP2003520656A (ja) | 2003-07-08 |
JP4234345B2 (ja) | 2009-03-04 |
CA2368999A1 (fr) | 2001-08-02 |
FR2804328A1 (fr) | 2001-08-03 |
EP1165214B1 (de) | 2009-11-25 |
DE60140588D1 (de) | 2010-01-07 |
ES2337231T3 (es) | 2010-04-22 |
US20030021826A1 (en) | 2003-01-30 |
CA2368999C (fr) | 2009-09-15 |
AU779469B2 (en) | 2005-01-27 |
WO2001054802A1 (fr) | 2001-08-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |