ATE446297T1 - Lactamverbindungen und deren medizinische verwendung - Google Patents

Lactamverbindungen und deren medizinische verwendung

Info

Publication number: ATE446297T1
Authority: AT; Austria
Prior art keywords: diabetic; medical use; lactam compounds; agent; adiposis
Prior art date: 2000-12-01

Application number

AT01998549T

Other languages

English (en)

Inventor

Y Iino

T Ikenoue

N Kondo

H Matsueda

T Hatanaka

R Hirama

Y Masuzawa

F Ohta

A Yamazaki

Original Assignee

Ajinomoto Kk

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-01

Filing date

2001-11-29

Publication date

2009-11-15

2001-11-29 Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk

2009-11-15 Application granted granted Critical

2009-11-15 Publication of ATE446297T1 publication Critical patent/ATE446297T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
- A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Diabetes (AREA)
Epidemiology (AREA)
Obesity (AREA)
Hematology (AREA)
Neurology (AREA)
Child & Adolescent Psychology (AREA)
Ophthalmology & Optometry (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Neurosurgery (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pyrrole Compounds (AREA)

AT01998549T 2000-12-01 2001-11-29 Lactamverbindungen und deren medizinische verwendung ATE446297T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP2000367175		2000-12-01
PCT/JP2001/010435 WO2002044180A1 (fr)	2000-12-01	2001-11-29	Composes de lactame et leur utilisation medicale

Publications (1)

Publication Number	Publication Date
ATE446297T1 true ATE446297T1 (de)	2009-11-15

Family

ID=18837660

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01998549T ATE446297T1 (de)	2000-12-01	2001-11-29	Lactamverbindungen und deren medizinische verwendung

Country Status (26)

Country	Link
US (3)	US7153850B2 (de)
EP (1)	EP1346993B1 (de)
JP (2)	JP3826400B2 (de)
KR (1)	KR100826818B1 (de)
CN (2)	CN100577651C (de)
AT (1)	ATE446297T1 (de)
AU (3)	AU2002218502B2 (de)
BG (1)	BG107857A (de)
BR (1)	BR0115852A (de)
CA (1)	CA2430124C (de)
CZ (1)	CZ20031520A3 (de)
DE (1)	DE60140270D1 (de)
ES (1)	ES2331299T3 (de)
HU (1)	HUP0400806A3 (de)
IL (1)	IL156158A0 (de)
MX (1)	MXPA03004876A (de)
NO (1)	NO325401B1 (de)
NZ (1)	NZ526164A (de)
PL (1)	PL362835A1 (de)
RU (1)	RU2287530C2 (de)
SK (1)	SK6582003A3 (de)
TW (1)	TWI241302B (de)
UA (1)	UA76969C2 (de)
WO (1)	WO2002044180A1 (de)
YU (1)	YU42603A (de)
ZA (1)	ZA200304100B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE446297T1 (de) *	2000-12-01	2009-11-15	Ajinomoto Kk	Lactamverbindungen und deren medizinische verwendung
RU2358738C2 (ru) *	2003-02-07	2009-06-20	Адзиномото Ко., Инк.	Лекарственные средства для лечения сахарного диабета
WO2005042536A1 (ja) *	2003-10-31	2005-05-12	Ajinomoto Co., Inc.	複素環を有する新規縮合多環式化合物及びその医薬用途
WO2005068467A1 (ja) *	2004-01-14	2005-07-28	Ajinomoto Co., Inc.	新規縮環化合物
CN101166742B (zh) *	2005-04-28	2011-07-13	味之素株式会社	新型内酰胺化合物
EP2157092A4 (de)	2007-04-11	2011-04-13	Ajinomoto Kk	Mittel zur behandlung von diabetes
WO2008139574A1 (ja) *	2007-04-27	2008-11-20	Ajinomoto Co., Inc.	ラクタム化合物の結晶形およびその製造方法
WO2008136393A1 (ja) *	2007-04-27	2008-11-13	Ajinomoto Co., Inc.	ラクタム化合物の結晶形およびその製造方法
WO2008139575A1 (ja) *	2007-04-27	2008-11-20	Ajinomoto Co., Inc.	経口投与用製剤
CN101619041B (zh) *	2008-07-02	2012-07-04	重庆华邦制药股份有限公司	一种二酮基含氮环化合物的合成方法及其中间体
JP2012180283A (ja) *	2009-07-02	2012-09-20	Ajinomoto Co Inc	ラクタム化合物の製造方法およびその製造中間体
JP2012180282A (ja) *	2009-07-02	2012-09-20	Ajinomoto Co Inc	ラクタム化合物の製造方法およびその製造中間体
KR20170095850A (ko) *	2014-12-22	2017-08-23	이에이 파마 가부시키가이샤	각막 상피 장애 치료제
US11548893B2 (en)	2017-07-15	2023-01-10	Arisan Therapeutics Inc.	Enantiomerically pure adamantane carboxamides for the treatment of filovirus infection
TWI820289B (zh) *	2019-01-23	2023-11-01	醣解生醫股份有限公司	β-內醯胺類化合物或其鹽於長效預防或治療葡萄糖代謝失調之用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US48847A (en) *		1865-07-18		Improvement in vessels for reception and transportation of night-soil
US189597A (en) *		1877-04-17		Improvement in portable wash-stands
CA2297407A1 (en)	1997-07-30	1999-02-11	American Home Products Corporation	Tricyclic vasopressin agonists
JP4204657B2 (ja) *	1997-12-05	2009-01-07	有限会社ケムフィズ	糖尿病の予防・治療剤
ATE446297T1 (de)	2000-12-01	2009-11-15	Ajinomoto Kk	Lactamverbindungen und deren medizinische verwendung
RU2358738C2 (ru) *	2003-02-07	2009-06-20	Адзиномото Ко., Инк.	Лекарственные средства для лечения сахарного диабета

2001
- 2001-11-29 AT AT01998549T patent/ATE446297T1/de not_active IP Right Cessation
- 2001-11-29 EP EP01998549A patent/EP1346993B1/de not_active Expired - Lifetime
- 2001-11-29 PL PL01362835A patent/PL362835A1/xx not_active Application Discontinuation
- 2001-11-29 SK SK658-2003A patent/SK6582003A3/sk unknown
- 2001-11-29 CA CA2430124A patent/CA2430124C/en not_active Expired - Fee Related
- 2001-11-29 DE DE60140270T patent/DE60140270D1/de not_active Expired - Lifetime
- 2001-11-29 WO PCT/JP2001/010435 patent/WO2002044180A1/ja active IP Right Grant
- 2001-11-29 AU AU2002218502A patent/AU2002218502B2/en not_active Ceased
- 2001-11-29 YU YU42603A patent/YU42603A/sh unknown
- 2001-11-29 CN CN200610095903A patent/CN100577651C/zh not_active Expired - Fee Related
- 2001-11-29 KR KR1020037007327A patent/KR100826818B1/ko not_active IP Right Cessation
- 2001-11-29 RU RU2003116126/04A patent/RU2287530C2/ru not_active IP Right Cessation
- 2001-11-29 ES ES01998549T patent/ES2331299T3/es not_active Expired - Lifetime
- 2001-11-29 TW TW090129582A patent/TWI241302B/zh not_active IP Right Cessation
- 2001-11-29 NZ NZ526164A patent/NZ526164A/en unknown
- 2001-11-29 CZ CZ20031520A patent/CZ20031520A3/cs unknown
- 2001-11-29 UA UA2003055026A patent/UA76969C2/uk unknown
- 2001-11-29 JP JP2002546550A patent/JP3826400B2/ja not_active Expired - Lifetime
- 2001-11-29 BR BR0115852-0A patent/BR0115852A/pt not_active Application Discontinuation
- 2001-11-29 HU HU0400806A patent/HUP0400806A3/hu unknown
- 2001-11-29 MX MXPA03004876A patent/MXPA03004876A/es active IP Right Grant
- 2001-11-29 IL IL15615801A patent/IL156158A0/xx unknown
- 2001-11-29 AU AU1850202A patent/AU1850202A/xx active Pending
- 2001-11-29 CN CNB018223559A patent/CN1269818C/zh not_active Expired - Fee Related
2003
- 2003-05-27 ZA ZA200304100A patent/ZA200304100B/en unknown
- 2003-05-28 NO NO20032439A patent/NO325401B1/no not_active IP Right Cessation
- 2003-05-29 BG BG107857A patent/BG107857A/bg unknown
- 2003-06-02 US US10/449,774 patent/US7153850B2/en not_active Expired - Fee Related
2006
- 2006-04-06 US US11/398,675 patent/US7326701B2/en not_active Expired - Fee Related
- 2006-05-12 JP JP2006134026A patent/JP4505753B2/ja not_active Expired - Fee Related
- 2006-11-24 AU AU2006241377A patent/AU2006241377B2/en not_active Ceased
2007
- 2007-11-30 US US11/948,288 patent/US7632830B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU2006241377A1 (en)	2006-12-14
CA2430124C (en)	2011-01-11
EP1346993B1 (de)	2009-10-21
UA76969C2 (en)	2006-10-16
AU2002218502B2 (en)	2006-09-21
SK6582003A3 (en)	2003-09-11
ZA200304100B (en)	2004-08-22
CA2430124A1 (en)	2002-06-06
TWI241302B (en)	2005-10-11
MXPA03004876A (es)	2004-01-27
US20060189597A1 (en)	2006-08-24
HUP0400806A3 (en)	2007-11-28
CN100577651C (zh)	2010-01-06
NZ526164A (en)	2004-09-24
CN1911915A (zh)	2007-02-14
NO20032439D0 (no)	2003-05-28
EP1346993A1 (de)	2003-09-24
US7326701B2 (en)	2008-02-05
JP4505753B2 (ja)	2010-07-21
KR20030051893A (ko)	2003-06-25
NO325401B1 (no)	2008-04-21
JP2006213732A (ja)	2006-08-17
BR0115852A (pt)	2003-12-23
AU1850202A (en)	2002-06-11
CN1269818C (zh)	2006-08-16
US7153850B2 (en)	2006-12-26
JP3826400B2 (ja)	2006-09-27
RU2287530C2 (ru)	2006-11-20
ES2331299T3 (es)	2009-12-29
JPWO2002044180A1 (ja)	2004-04-02
CZ20031520A3 (cs)	2003-10-15
US7632830B2 (en)	2009-12-15
YU42603A (sh)	2006-03-03
HUP0400806A2 (hu)	2004-07-28
WO2002044180A1 (fr)	2002-06-06
BG107857A (bg)	2004-06-30
US20040048847A1 (en)	2004-03-11
IL156158A0 (en)	2003-12-23
EP1346993A4 (de)	2005-12-21
PL362835A1 (en)	2004-11-02
US20080096862A1 (en)	2008-04-24
CN1487940A (zh)	2004-04-07
DE60140270D1 (de)	2009-12-03
NO20032439L (no)	2003-07-18
KR100826818B1 (ko)	2008-05-02
AU2006241377B2 (en)	2009-01-08

Publication	Publication Date	Title
ATE446297T1 (de)	2009-11-15	Lactamverbindungen und deren medizinische verwendung
NL300985I2 (en)	2019-11-21	mogamulizumab
DE60022226D1 (de)	2005-09-29	Benzimidazolverbindungen die nociceptinrezeptoraffinität haben
MXPA03007712A (es)	2004-03-16	Sales farmaceuticas.
BR9808581A (pt)	2000-05-30	Estabilização de benzimidazóis sensìveis a ácido com combinações de aminoácido/ciclodextrina
SE9903759D0 (sv)	1999-10-18	Pharmaceutically active compounds
ATE232862T1 (de)	2003-03-15	Oxazolidinon derivate und diese enthaltende pharmazeutische zusammensetzungen
AU2001276689A1 (en)	2002-02-13	Novel remedies for cancer
DE60233251D1 (de)	2009-09-17	4,4-difluor-1,2,3,4-tetrahydro-5h-1-benzazepinderivate und deren salze
MXPA04002510A (es)	2004-05-31	Combinacion de opioides selectos con antagonistas de muscarina para tratamiento de incontinencia urinaria.
ATE273704T1 (de)	2004-09-15	Ophthalmische histamin-enthaltende zusammensetzungen und deren verwendung
NO985571L (no)	1999-01-27	Legemiddel for autoimmunsykdommer
ATE456651T1 (de)	2010-02-15	Metalloprotease mit aggrecanase-aktivität
PT896822E (pt)	2003-07-31	4-aminopirrolo (3,2-d)pirimidinas como antagonistas do receptor de neuropeptideo y
DE69941897D1 (de)	2010-02-25	Arzneimittel für nicht-cardiogene diastolische dysfunktion
ITMI20000293A0 (it)	2000-02-18	Derivati del 3,9-diazabiciclo [3.3.1]nonano ad attivita' analgesica
EP1130018A4 (de)	2003-01-15	Heilmittel gegen drogenabhängigkeit
DE69012742D1 (de)	1994-10-27	Azolderivate und fungizide Medikamente, diese als wirkende Komponente enthaltend.
FR2716193B1 (fr)	1996-04-05	Dérivés de 1[2-(1h-inden-3-yl)ethyl]-4-(naphtalen-1-yl)piperazine, leur préparation et leur application en thérapeutique.
AR035986A1 (es)	2004-08-04	Uso de derivados anti-convulsivos para la manufactura de un medicamento util para el tratamiento del temblor esencial
ATE285236T1 (de)	2005-01-15	Antivirale zusammensetzungen enthaltend yohimbin als therapeutischen wirkstoff
EP1464636A4 (de)	2006-01-11	Neue substanz mit antitumorwirkung/entzündungshemmender wirkung
EP1466909A4 (de)	2005-12-07	Halogenbenzylaminopropionsäurederivate
EP1262482A4 (de)	2004-06-30	Neue verbindung mit anti-malaria-aktivität
WO2003083487A3 (en)	2003-12-31	Method of screening of compounds inducing a prolonged qt intervalon the electrocardiogram

Legal Events

Date	Code	Title	Description
2010-04-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties