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ATE444759T1 - Verfahren zur herstellung eines knochenzements - Google Patents

Verfahren zur herstellung eines knochenzements

Info

Publication number
ATE444759T1
ATE444759T1 AT01993469T AT01993469T ATE444759T1 AT E444759 T1 ATE444759 T1 AT E444759T1 AT 01993469 T AT01993469 T AT 01993469T AT 01993469 T AT01993469 T AT 01993469T AT E444759 T1 ATE444759 T1 AT E444759T1
Authority
AT
Austria
Prior art keywords
bone
demineralized
bone cement
putty
gel
Prior art date
Application number
AT01993469T
Other languages
English (en)
Inventor
El Gendler
Eli Gendler
Simon Gendler
Original Assignee
El Gendler
Eli Gendler
Simon Gendler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by El Gendler, Eli Gendler, Simon Gendler filed Critical El Gendler
Application granted granted Critical
Publication of ATE444759T1 publication Critical patent/ATE444759T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/28—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools or methods for implanting or extracting artificial joints, accessories, bone grafts or substitutes, or particular adaptations therefor
    • A61F2/4644—Preparation of bone graft, bone plugs or bone dowels, e.g. grinding or milling bone material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/30004—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis
    • A61F2002/30059—Material related properties of the prosthesis or of a coating on the prosthesis the prosthesis being made from materials having different values of a given property at different locations within the same prosthesis differing in bone mineralization, e.g. made from both mineralized and demineralized adjacent parts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Materials For Medical Uses (AREA)
AT01993469T 2000-11-13 2001-11-01 Verfahren zur herstellung eines knochenzements ATE444759T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/711,716 US6576249B1 (en) 2000-11-13 2000-11-13 Bone putty and method
PCT/US2001/044848 WO2002038163A1 (en) 2000-11-13 2001-11-01 Bone putty and method

Publications (1)

Publication Number Publication Date
ATE444759T1 true ATE444759T1 (de) 2009-10-15

Family

ID=24859218

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01993469T ATE444759T1 (de) 2000-11-13 2001-11-01 Verfahren zur herstellung eines knochenzements

Country Status (6)

Country Link
US (1) US6576249B1 (de)
EP (1) EP1341545B1 (de)
AT (1) ATE444759T1 (de)
DE (1) DE60140142D1 (de)
RU (1) RU2003117454A (de)
WO (1) WO2002038163A1 (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
WO2003020327A2 (en) * 2001-09-06 2003-03-13 Bone Sa A cross-linked collagenous biomaterial
US20130101675A1 (en) * 2001-09-06 2013-04-25 Nicolaas Duneas Cross-Linked Non-Demineralized Collagenous Biomaterial
US7744597B2 (en) 2002-06-26 2010-06-29 Lifenet Health Device and process for producing fiber products and fiber products produced thereby
US7498040B2 (en) * 2005-10-12 2009-03-03 Lifenet Health Compositions for repair of defects in osseous tissues, and methods of making the same
US7494811B2 (en) 2003-05-01 2009-02-24 Lifenet Health In vitro growth of tissues suitable to the formation of bone and bone forming tissue formed thereby
AU2004279319B2 (en) 2003-09-23 2010-11-04 Abyrx, Inc Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
KR20060121921A (ko) 2003-09-23 2006-11-29 오르토테라퓨틱스 엘엘씨 생흡수성 퍼티형 지혈 임플란트
US7955616B2 (en) * 2003-09-23 2011-06-07 Orthocon, Inc. Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
US20050074476A1 (en) * 2003-10-03 2005-04-07 El Gendler Cartilidge and bone induction by artificially perforated organic bone matrix augmented by undifferentiated cells suspended in bone gel
US7534264B2 (en) * 2004-01-28 2009-05-19 Ultradent Products, Inc. Delivery system for bone growth promoting material
US20050244450A1 (en) * 2004-04-28 2005-11-03 Reddi A H Heat-treated implantable bone material
US7678385B2 (en) * 2004-04-28 2010-03-16 Biomet Manufacturing Corp. Irradiated implantable bone material
US8603528B2 (en) * 2004-09-16 2013-12-10 Abyrx, Inc. Compositions and method for the reduction of post-operative pain
US20060083769A1 (en) 2004-10-14 2006-04-20 Mukesh Kumar Method and apparatus for preparing bone
US7670384B2 (en) * 2004-10-14 2010-03-02 Biomet Manufacturing Corp. Bone graft composition comprising a bone material and a carrier comprising denatured demineralized bone
DE102005030614B4 (de) 2005-06-30 2014-05-08 Biotissue Ag Zellfreies Transplantat, dessen Verwendung, Verfahren zu dessen Herstellung, dabei hergestellte Matrix mit Gel und Verfahren zur Herstellung dieser Matrix mit Gel
US9005646B2 (en) 2005-10-12 2015-04-14 Lifenet Health Compositions for repair of defects in tissues, and methods of making the same
US20070083270A1 (en) * 2005-10-12 2007-04-12 Leila Masinaei Orthopedic prosthetic devices containing compositions for repair of defects in osseous tissues
US7498041B2 (en) * 2005-10-12 2009-03-03 Lifenet Health Composition for repair of defects in osseous tissues
US20070092494A1 (en) * 2005-10-26 2007-04-26 Biomet Manufacturing Corp. Composition for wound healing using lyophilized skin or skin-derived collagen
US7785634B2 (en) * 2006-02-27 2010-08-31 Globus Medical, Inc. Bone graft materials derived from mineralized gelatin
US7892577B2 (en) 2006-02-27 2011-02-22 Globus Medical, Inc. Bone graft materials derived from mineralized gelatin
DE102006047346A1 (de) 2006-10-06 2008-04-10 Transtissue Technologies Gmbh Matrix-Gel-Transplantat ohne Zellen
US7718616B2 (en) 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
US20080233203A1 (en) 2007-03-21 2008-09-25 Jennifer Woodell-May Porous orthapedic materials coated with demineralized bone matrix
CA2685956A1 (en) * 2007-05-04 2008-11-13 Perth Bone & Tissue Bank A method for treating inflammation and controlled-release material capable of providing same
US20090131867A1 (en) 2007-11-16 2009-05-21 Liu Y King Steerable vertebroplasty system with cavity creation element
US20090131886A1 (en) 2007-11-16 2009-05-21 Liu Y King Steerable vertebroplasty system
US9510885B2 (en) 2007-11-16 2016-12-06 Osseon Llc Steerable and curvable cavity creation system
EP2222348B1 (de) * 2007-12-21 2013-07-03 RTI Biologics, Inc. Osteoinduktive kittmassen und verfahren zur herstellung derartiger kittmassen
NZ592238A (en) * 2008-09-16 2012-11-30 Proximagen Ltd Pharmaceutical compositions comprising 4-isopropyl-1,4,6,7-tetrahydro-5H-imidazo[4,5-c]pyridine derivatives
US20130259902A1 (en) * 2008-11-04 2013-10-03 Ying Fan Carrier material for bone forming cells
US20100298832A1 (en) 2009-05-20 2010-11-25 Osseon Therapeutics, Inc. Steerable curvable vertebroplasty drill
WO2011137377A1 (en) 2010-04-29 2011-11-03 Dfine, Inc. System for use in treatment of vertebral fractures
JP2013542837A (ja) 2010-11-15 2013-11-28 ジンマー オーソバイオロジクス，インコーポレイティド 骨空隙充填剤
WO2014182666A1 (en) 2013-05-06 2014-11-13 Bio-Rad Laboratories, Inc. Stabilization of labile analytes in reference materials
FR3020273B1 (fr) 2014-04-25 2021-04-16 Biobank Procede de fabrication de pate osseuse
EP3297694A1 (de) 2015-05-21 2018-03-28 Musculoskeletal Transplant Foundation Modifizierte demineralisierte kortikale knochenfasern
US10549011B2 (en) * 2015-10-26 2020-02-04 Osteolife Biomedical, Llc Bone putty and gel systems and methods
US20170128633A1 (en) 2015-11-10 2017-05-11 Theodore Malinin Bioactive Implants and Methods of Making and Using
US11253630B2 (en) 2016-04-22 2022-02-22 Vivex Biologics Group, Inc. Malleable demineralized bone composition and method of manufacture
US10463767B2 (en) 2016-04-22 2019-11-05 Vivex Biologics Group, Inc. Moldable bone composition
US10596298B2 (en) 2016-04-22 2020-03-24 Vivex Biologics Group, Inc. Malleable demineralized bone composition and method of manufacture
US9788950B1 (en) 2016-04-22 2017-10-17 Vivex Biomedical, Inc. Cohesive bone composition
US11253629B2 (en) 2016-04-22 2022-02-22 Vivex Biologics Group, Inc. Bone gel sheet composition and method of manufacture
WO2018081279A1 (en) 2016-10-27 2018-05-03 Dfine, Inc. Articulating osteotome with cement delivery channel
AU2017363356B2 (en) 2016-11-28 2023-02-09 Dfine, Inc. Tumor ablation devices and related methods
US10470781B2 (en) 2016-12-09 2019-11-12 Dfine, Inc. Medical devices for treating hard tissues and related methods
US10660656B2 (en) 2017-01-06 2020-05-26 Dfine, Inc. Osteotome with a distal portion for simultaneous advancement and articulation
WO2020097334A1 (en) 2018-11-08 2020-05-14 Dfine, Inc. Ablation systems with parameter-based modulation and related devices and methods
US11207445B2 (en) 2019-07-09 2021-12-28 Community Blood Center Allograft bone putty and methods of making the same
WO2021055617A1 (en) 2019-09-18 2021-03-25 Merit Medical Systems, Inc. Osteotome with inflatable portion and multiwire articulation

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172128A (en) * 1975-03-26 1979-10-23 Erhard Thiele Process of degrading and regenerating bone and tooth material and products
US4932973A (en) 1983-09-30 1990-06-12 El Gendler Cartilage and bone induction by artificially perforated organic bone matrix
FR2625412B1 (fr) * 1987-12-30 1990-06-29 Mero Rousselot Satia Procede continu d'obtention de gelatine a partir de poudre d'os et gelatine obtenue
US5290558A (en) 1989-09-21 1994-03-01 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US5073373A (en) 1989-09-21 1991-12-17 Osteotech, Inc. Flowable demineralized bone powder composition and its use in bone repair
US5236456A (en) * 1989-11-09 1993-08-17 Osteotech, Inc. Osteogenic composition and implant containing same
EP0483944B1 (de) 1990-10-31 1995-07-05 El Gendler Flexible Membrane hergestellt aus organischer Knochenmatrix zum Ausbessern und Wiederherstellen von Knochen
US5092887A (en) 1991-08-12 1992-03-03 El Gendler Artificial ligament produced from demineralized bone for the replacement and augmentation of ligaments, tendons and other fibrous connective tissue
US5314476A (en) 1992-02-04 1994-05-24 Osteotech, Inc. Demineralized bone particles and flowable osteogenic composition containing same
US5507813A (en) 1993-12-09 1996-04-16 Osteotech, Inc. Shaped materials derived from elongate bone particles
US5904716A (en) 1995-04-26 1999-05-18 Gendler; El Method for reconstituting cartilage tissue using demineralized bone and product thereof
WO1998035653A1 (en) * 1997-02-13 1998-08-20 Benedict, James, A. Implantable collagen-containing putty material
US20020098222A1 (en) * 1997-03-13 2002-07-25 John F. Wironen Bone paste
US20020076429A1 (en) * 1998-01-28 2002-06-20 John F. Wironen Bone paste subjected to irradiative and thermal treatment
US6030635A (en) 1998-02-27 2000-02-29 Musculoskeletal Transplant Foundation Malleable paste for filling bone defects

Also Published As

Publication number Publication date
RU2003117454A (ru) 2004-11-27
DE60140142D1 (de) 2009-11-19
EP1341545B1 (de) 2009-10-07
EP1341545A4 (de) 2004-08-11
EP1341545A1 (de) 2003-09-10
WO2002038163A1 (en) 2002-05-16
US6576249B1 (en) 2003-06-10

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