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ATE442842T1 - Verwendung von urokinase-inhibitoren zur behandlung und/oder vorbeugung von amyotrophischer lateralsklerose (als) - Google Patents

Verwendung von urokinase-inhibitoren zur behandlung und/oder vorbeugung von amyotrophischer lateralsklerose (als)

Info

Publication number
ATE442842T1
ATE442842T1 AT06754517T AT06754517T ATE442842T1 AT E442842 T1 ATE442842 T1 AT E442842T1 AT 06754517 T AT06754517 T AT 06754517T AT 06754517 T AT06754517 T AT 06754517T AT E442842 T1 ATE442842 T1 AT E442842T1
Authority
AT
Austria
Prior art keywords
inhibitors
lateral sclerosis
amyotrophic lateral
urocinasis
als
Prior art date
Application number
AT06754517T
Other languages
English (en)
Inventor
Stefan Lorenzl
Original Assignee
Wilex Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wilex Ag filed Critical Wilex Ag
Application granted granted Critical
Publication of ATE442842T1 publication Critical patent/ATE442842T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT06754517T 2005-06-24 2006-06-22 Verwendung von urokinase-inhibitoren zur behandlung und/oder vorbeugung von amyotrophischer lateralsklerose (als) ATE442842T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69343205P 2005-06-24 2005-06-24
PCT/EP2006/006029 WO2006136419A2 (en) 2005-06-24 2006-06-22 Use of urokinase inhibitors for the treatment and/or prevention of neuropathological diseases

Publications (1)

Publication Number Publication Date
ATE442842T1 true ATE442842T1 (de) 2009-10-15

Family

ID=37570795

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06754517T ATE442842T1 (de) 2005-06-24 2006-06-22 Verwendung von urokinase-inhibitoren zur behandlung und/oder vorbeugung von amyotrophischer lateralsklerose (als)

Country Status (13)

Country Link
US (1) US8093258B2 (de)
EP (2) EP1893185B1 (de)
JP (1) JP2008543900A (de)
KR (1) KR20080027875A (de)
AT (1) ATE442842T1 (de)
AU (1) AU2006261099A1 (de)
CA (1) CA2612262A1 (de)
DE (1) DE602006009257D1 (de)
ES (1) ES2329286T3 (de)
HK (1) HK1109862A1 (de)
MX (1) MX2007016439A (de)
RU (1) RU2410087C2 (de)
WO (1) WO2006136419A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3139850A1 (en) * 2019-05-10 2020-11-19 Talengen International Limited Method and medicine for treating amyotrophic lateral sclerosis

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340833A (en) 1992-05-01 1994-08-23 Eisai Co., Ltd. Urokinase inhibitors
US5550213A (en) 1993-12-27 1996-08-27 Rutgers, The State University Of New Jersey Inhibitors of urokinase plasminogen activator
US5952307A (en) 1994-01-21 1999-09-14 Georgia Tech Research Corp. Basic α-aminoalkylphosphonate derivatives
CH689611A5 (de) 1995-03-01 1999-07-15 Pentapharm Ag Urokinase-Inhibitoren.
AUPO227896A0 (en) 1996-09-13 1996-10-03 Fujisawa Pharmaceutical Co., Ltd. Novel compounds and their preparation
ATE247130T1 (de) 1997-04-11 2003-08-15 Wilex Ag Inhibitoren für den urokinaserezeptor
ZA986594B (en) 1997-07-25 1999-01-27 Abbott Lab Urokinase inhibitors
GB9721964D0 (en) 1997-10-16 1997-12-17 Pfizer Ltd Isoquinolines
AU765072B2 (en) 1998-02-09 2003-09-11 3-Dimensional Pharmaceuticals, Inc. Heteroaryl amidines, methylamidines and guanidines as protease inhibitors, in particular as urokinase inhibitors
BR9912327B1 (pt) 1998-07-20 2013-11-12 Inibidores da uroquinase
US6576613B1 (en) 1998-07-24 2003-06-10 Corvas International, Inc. Title inhibitors of urokinase
WO2000005214A2 (en) 1998-07-24 2000-02-03 Pfizer Inc. Isoquinolines as urokinase inhibitors
WO2000006154A1 (fr) 1998-07-29 2000-02-10 Taiho Pharmaceutical Company, Ltd. Inhibiteurs de la production d'urokinase, inhibiteurs de l'angiogenese et procedes de prevention ou de traitement les utilisant
WO2000017158A1 (de) 1998-09-18 2000-03-30 Pentapharm Ag Urokinase-inhibitoren
GB9908410D0 (en) 1999-04-13 1999-06-09 Pfizer Ltd Pyridines
DE19940389A1 (de) 1999-08-25 2001-03-01 Wilex Biotechnology Gmbh Selektive Inhibitoren des Urokinase-Plasminogen Aktivators
EP1242366A1 (de) 1999-12-15 2002-09-25 Axys Pharmaceuticals, Inc. Salicylamide als serine-protease- und factor-xa-inhibitoren
US6207701B1 (en) 2000-01-28 2001-03-27 Abbott Laboratories Urokinase inhibitors
DE10013715A1 (de) 2000-03-20 2001-09-27 Wilex Biotechnology Gmbh Hochselektive Inhibitoren des Urokinase-Plasminogenaktivators
DE10029014A1 (de) 2000-06-15 2001-12-20 Univ Schiller Jena Urokinase-Hemmstoffe
DE60034447T2 (de) 2000-08-11 2008-02-14 Wilex Ag Nicht-kovalente Urokinase-und Angiogenese-Inhibitoren
CA2387002A1 (en) 2000-08-11 2002-02-21 Corvas International, Inc. Non-covalent inhibitors of urokinase and blood vessel formation
ATE386029T1 (de) 2001-03-21 2008-03-15 Wilex Ag Urokinase-inhibitoren
AU2002364713A1 (en) 2001-12-04 2003-06-17 Corvas International, Inc. Aromatic heterocyclic non-covalent inhibitors of urokinase and blood vessel formation
EP1453852B1 (de) 2001-12-12 2007-01-17 Wilex AG Selektive arylguanidinpeptide als urokinaseinhibitoren
AU2003219039A1 (en) 2002-03-11 2003-09-22 Curacyte Ag Urokinase inhibitors, production and use thereof
DE10225876A1 (de) 2002-06-11 2003-12-24 Wilex Ag Guanidinophenylalaninverbindungen als Urokinase-Inhibitoren
MXPA05011762A (es) * 2003-05-05 2006-03-30 Paion Deutschland Gmbh Antagonistas de receptor de glutamato como neuroprotectores.
DE10323898A1 (de) 2003-05-26 2004-12-23 Wilex Ag Hydroxyamidin- und Hydroxyguanidin-Verbindungen als Urokinase-Hemmstoffe

Also Published As

Publication number Publication date
US20090069251A1 (en) 2009-03-12
EP1893185A2 (de) 2008-03-05
HK1109862A1 (en) 2008-06-27
EP2087885A1 (de) 2009-08-12
EP1893185B1 (de) 2009-09-16
RU2008102730A (ru) 2009-07-27
ES2329286T3 (es) 2009-11-24
WO2006136419B1 (en) 2007-05-31
DE602006009257D1 (de) 2009-10-29
AU2006261099A1 (en) 2006-12-28
WO2006136419A3 (en) 2007-04-19
CA2612262A1 (en) 2006-12-28
MX2007016439A (es) 2008-03-04
KR20080027875A (ko) 2008-03-28
JP2008543900A (ja) 2008-12-04
WO2006136419A2 (en) 2006-12-28
US8093258B2 (en) 2012-01-10
RU2410087C2 (ru) 2011-01-27

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