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ATE319471T1 - Chemokin-muntanten mit verbesserter oraler bioverfügbarkeit - Google Patents

Chemokin-muntanten mit verbesserter oraler bioverfügbarkeit

Info

Publication number
ATE319471T1
ATE319471T1 AT03730169T AT03730169T ATE319471T1 AT E319471 T1 ATE319471 T1 AT E319471T1 AT 03730169 T AT03730169 T AT 03730169T AT 03730169 T AT03730169 T AT 03730169T AT E319471 T1 ATE319471 T1 AT E319471T1
Authority
AT
Austria
Prior art keywords
mantants
chemokine
oral bioavailability
improved oral
improved
Prior art date
Application number
AT03730169T
Other languages
English (en)
Inventor
Amanda Proudfoot
Marie Kosco-Vilbois
Timothy Wells
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of ATE319471T1 publication Critical patent/ATE319471T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/195Chemokines, e.g. RANTES
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03730169T 2002-04-04 2003-03-31 Chemokin-muntanten mit verbesserter oraler bioverfügbarkeit ATE319471T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02100339 2002-04-04

Publications (1)

Publication Number Publication Date
ATE319471T1 true ATE319471T1 (de) 2006-03-15

Family

ID=28685984

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03730169T ATE319471T1 (de) 2002-04-04 2003-03-31 Chemokin-muntanten mit verbesserter oraler bioverfügbarkeit

Country Status (13)

Country Link
US (1) US7335350B2 (de)
EP (1) EP1494703B1 (de)
JP (1) JP2005529099A (de)
AT (1) ATE319471T1 (de)
AU (1) AU2003240758B2 (de)
CA (1) CA2480692A1 (de)
DE (1) DE60303929T2 (de)
DK (1) DK1494703T3 (de)
ES (1) ES2254938T3 (de)
IL (1) IL164375A0 (de)
PT (1) PT1494703E (de)
SI (1) SI1494703T1 (de)
WO (1) WO2003084562A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007113285A2 (en) * 2006-03-31 2007-10-11 Biotherapix Molecular Medicines S.L.U. Mono- and bifunctional molecules with ability to bind to g protein-coupled receptors
US8012474B2 (en) 2007-08-02 2011-09-06 Nov Immune S.A. Anti-RANTES antibodies
WO2011031757A1 (en) * 2009-09-11 2011-03-17 Centocor Ortho Biotech Inc. Serum markers for identification of cutaneous systemic sclerosis subjects
CA3101052A1 (en) 2018-05-28 2019-12-05 ORION Biotechnology Switzerland Sarl Methods of inhibiting cerebral inflammation

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5739103A (en) * 1993-11-12 1998-04-14 Dana-Farber Cancer Institute Chemokine N-terminal deletion mutations
US5871723A (en) * 1995-06-06 1999-02-16 The Regent Of The University Of Michigan CXC chemokines as regulators of angiogenesis
WO1998006751A1 (en) 1996-08-16 1998-02-19 Research Corporation Technologies, Inc. Mcp-3, rantes and mip-1alpha receptor antagonists
AU4561497A (en) * 1996-09-25 1998-04-17 British Biotech Pharmaceuticals Limited Human rantes mutants incapable of aggregate formation
US6214540B1 (en) * 1997-03-26 2001-04-10 University Of Maryland Biotechnology Institute Chemokines that inhibit immunodeficiency virus infection and methods based thereon
AU2415599A (en) * 1997-12-23 1999-07-19 Fondazione Centro San Raffaele Del Monte Tabor Rantes mutants and therapeutic applications thereof
JP3349439B2 (ja) 1998-07-08 2002-11-25 日清紡績株式会社 ポリアセタール樹脂組成物
US6316420B1 (en) * 1998-07-28 2001-11-13 Technion Research And Development Foundation Ltd. DNA cytokine vaccines and use of same for protective immunity against multiple sclerosis
AU2740900A (en) 1999-01-29 2000-08-18 Millennium Pharmaceuticals, Inc. Method of treating demyelinating inflammatory disease using ccr1 antagonists
UA77950C2 (en) 2000-10-04 2007-02-15 Applied Research Systems Use of mutants of cc chemokines for treatment of multiple sclerosis

Also Published As

Publication number Publication date
DE60303929T2 (de) 2006-08-10
CA2480692A1 (en) 2003-10-16
EP1494703B1 (de) 2006-03-08
IL164375A0 (en) 2005-12-18
AU2003240758A1 (en) 2003-10-20
WO2003084562A1 (en) 2003-10-16
ES2254938T3 (es) 2006-06-16
EP1494703A1 (de) 2005-01-12
PT1494703E (pt) 2006-05-31
US20050220759A1 (en) 2005-10-06
DK1494703T3 (da) 2006-06-26
SI1494703T1 (sl) 2006-06-30
AU2003240758B2 (en) 2008-03-13
DE60303929D1 (de) 2006-05-04
JP2005529099A (ja) 2005-09-29
US7335350B2 (en) 2008-02-26

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