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ATE319473T1 - Melagatran zur behandlung von entzündungen - Google Patents

Melagatran zur behandlung von entzündungen

Info

Publication number
ATE319473T1
ATE319473T1 AT00902232T AT00902232T ATE319473T1 AT E319473 T1 ATE319473 T1 AT E319473T1 AT 00902232 T AT00902232 T AT 00902232T AT 00902232 T AT00902232 T AT 00902232T AT E319473 T1 ATE319473 T1 AT E319473T1
Authority
AT
Austria
Prior art keywords
melagatran
inflammation
treatment
prodrug
medicament
Prior art date
Application number
AT00902232T
Other languages
English (en)
Inventor
Ian Kirk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of ATE319473T1 publication Critical patent/ATE319473T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
AT00902232T 1999-01-13 2000-01-13 Melagatran zur behandlung von entzündungen ATE319473T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9900070A SE9900070D0 (sv) 1999-01-13 1999-01-13 New use

Publications (1)

Publication Number Publication Date
ATE319473T1 true ATE319473T1 (de) 2006-03-15

Family

ID=20414074

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00902232T ATE319473T1 (de) 1999-01-13 2000-01-13 Melagatran zur behandlung von entzündungen

Country Status (20)

Country Link
US (3) US6683054B1 (de)
EP (1) EP1150704B1 (de)
JP (1) JP2002534477A (de)
KR (1) KR100701539B1 (de)
CN (1) CN1170592C (de)
AT (1) ATE319473T1 (de)
AU (1) AU767077B2 (de)
BR (1) BR0007452A (de)
CA (1) CA2356611A1 (de)
CY (1) CY1107465T1 (de)
DE (1) DE60026491T2 (de)
DK (1) DK1150704T3 (de)
ES (1) ES2257282T3 (de)
IL (1) IL143985A0 (de)
NO (1) NO20013414L (de)
NZ (1) NZ512713A (de)
PT (1) PT1150704E (de)
SE (1) SE9900070D0 (de)
WO (1) WO2000041716A1 (de)
ZA (1) ZA200105275B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9900070D0 (sv) * 1999-01-13 1999-01-13 Astra Ab New use
US6462021B1 (en) 2000-11-06 2002-10-08 Astrazeneca Ab Use of low molecular weight thrombin inhibitor
DE10064797A1 (de) * 2000-12-22 2002-06-27 Knoll Ag Orale und parenterale pharmazeutische Formulierung, umfassend eine niedermolekulare Thrombininhibitor-Pro-Pharmakon
SE0101762D0 (sv) * 2001-05-18 2001-05-18 Astrazeneca Ab New use
DE10133786A1 (de) * 2001-07-16 2003-02-06 Boehringer Ingelheim Pharma Verwendung von Thrombin-Inhibitoren zur Behandlung von Arthritis
SE0103590D0 (sv) * 2001-10-26 2001-10-26 Astrazeneca Ab New Combination
SE0200198D0 (sv) * 2002-01-23 2002-01-23 Astrazeneca Ab New use
SE0203349D0 (sv) * 2002-11-12 2002-11-12 Astrazeneca Ab New use
MX355038B (es) 2010-03-30 2018-03-28 Verseon Corp Compuestos aromáticos multisustituidos como inhibidores de trombina.
CN110179795A (zh) 2013-03-15 2019-08-30 维颂公司 作为丝氨酸蛋白酶抑制剂的多取代芳族化合物的制药用途
RU2015144193A (ru) 2013-03-15 2017-04-24 Версеон Корпорейшн Галогенпиразолы в качестве ингибиторов тромбина
JP2017528486A (ja) 2014-09-17 2017-09-28 ヴァーセオン コーポレイション セリンプロテアーゼ阻害剤としてのピラゾリル置換ピリドン化合物
JP2018506563A (ja) 2015-02-27 2018-03-08 ヴァーセオン コーポレイション セリンプロテアーゼ阻害剤としての置換ピラゾール化合物
CN113164765A (zh) 2018-07-13 2021-07-23 维颂国际公司 凝血酶抑制剂、制剂及其用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9301916D0 (sv) 1993-06-03 1993-06-03 Ab Astra New peptides derivatives
US6042821A (en) * 1995-11-21 2000-03-28 Smithkline Beecham Corporation Method of treating sepsis with chemokines
AR005245A1 (es) * 1995-12-21 1999-04-28 Astrazeneca Ab Prodrogas de inhibidores de trombina, una formulación farmaceutica que las comprende, el uso de dichas prodrogas para la manufactura de un medicamento y un procedimiento para su preparacion
SE9600216D0 (sv) 1996-01-18 1996-01-18 Hans Arne Hansson Styrning av läkningsprocesser
US5669754A (en) * 1996-04-22 1997-09-23 Advanced Dynamics Corporation Ltd. Method and apparatus for collecting plates
SE9601556D0 (sv) 1996-04-24 1996-04-24 Astra Ab New pharmaceutical formulation of a thrombin inhibitor for parenteral use
SE9603724D0 (sv) * 1996-10-11 1996-10-11 Astra Ab New pharmaceutical parenteral formulation of a thrombin inhibitor
SE9802974D0 (sv) 1998-09-03 1998-09-03 Astra Ab New crystalline forms
CA2345641A1 (en) 1998-09-28 2000-04-06 Merck & Co., Inc. A method for treating inflammatory diseases by administering a thrombin inhibitor
SE9900070D0 (sv) * 1999-01-13 1999-01-13 Astra Ab New use
AR023510A1 (es) 1999-04-21 2002-09-04 Astrazeneca Ab Un equipo de partes, formulacion farmaceutica y uso de un inhibidor de trombina.

Also Published As

Publication number Publication date
AU2336100A (en) 2000-08-01
NO20013414D0 (no) 2001-07-10
KR20010101492A (ko) 2001-11-14
PT1150704E (pt) 2006-06-30
IL143985A0 (en) 2002-04-21
US20080058303A1 (en) 2008-03-06
CY1107465T1 (el) 2012-12-19
EP1150704A1 (de) 2001-11-07
ZA200105275B (en) 2002-09-26
DK1150704T3 (da) 2006-06-12
EP1150704B1 (de) 2006-03-08
ES2257282T3 (es) 2006-08-01
CN1170592C (zh) 2004-10-13
BR0007452A (pt) 2001-10-16
CA2356611A1 (en) 2000-07-20
NZ512713A (en) 2004-10-29
DE60026491T2 (de) 2006-11-02
DE60026491D1 (de) 2006-05-04
WO2000041716A1 (en) 2000-07-20
SE9900070D0 (sv) 1999-01-13
CN1341028A (zh) 2002-03-20
US6683054B1 (en) 2004-01-27
AU767077B2 (en) 2003-10-30
KR100701539B1 (ko) 2007-03-30
JP2002534477A (ja) 2002-10-15
NO20013414L (no) 2001-07-10
US20040082518A1 (en) 2004-04-29

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