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ATE31535T1 - Cephalosporinverbindungen. - Google Patents

Cephalosporinverbindungen.

Info

Publication number
ATE31535T1
ATE31535T1 AT82303746T AT82303746T ATE31535T1 AT E31535 T1 ATE31535 T1 AT E31535T1 AT 82303746 T AT82303746 T AT 82303746T AT 82303746 T AT82303746 T AT 82303746T AT E31535 T1 ATE31535 T1 AT E31535T1
Authority
AT
Austria
Prior art keywords
pyridiniummethyl
ceph
carboxylate
salts
preparation
Prior art date
Application number
AT82303746T
Other languages
English (en)
Inventor
Gordon Christopher David Smith
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE31535T1 publication Critical patent/ATE31535T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/40—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT82303746T 1981-07-17 1982-07-16 Cephalosporinverbindungen. ATE31535T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8122147 1981-07-17
EP82303746A EP0070706B1 (de) 1981-07-17 1982-07-16 Cephalosporinverbindungen

Publications (1)

Publication Number Publication Date
ATE31535T1 true ATE31535T1 (de) 1988-01-15

Family

ID=10523327

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82303746T ATE31535T1 (de) 1981-07-17 1982-07-16 Cephalosporinverbindungen.

Country Status (7)

Country Link
US (2) US4563523A (de)
EP (1) EP0070706B1 (de)
JP (1) JPS5823698A (de)
AT (1) ATE31535T1 (de)
AU (1) AU557274B2 (de)
DE (1) DE3277870D1 (de)
ZA (1) ZA825095B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3316797A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
DE3316798A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
JPS60176300U (ja) * 1984-04-23 1985-11-21 海洋工業株式会社 揚水筒
CN100344635C (zh) * 2003-07-22 2007-10-24 广州白云山制药股份有限公司 7－苯乙酰氨基－3－吡啶甲基－3－头孢菌素－4－羧酸对甲氧苄酯晶体及其制备方法
US8198434B2 (en) * 2008-05-07 2012-06-12 Idexx Laboratories, Inc. Process for preparing cefsulodin sodium

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB953695A (en) * 1959-08-04 1964-03-25 Nat Res Dev Derivatives of cephalosporin c
US3270009A (en) * 1961-08-23 1966-08-30 Lilly Co Eli Carbocyclic-substituted aliphatic cephalosporins
NL130098C (de) * 1963-07-15
US3498979A (en) * 1967-04-03 1970-03-03 Glaxo Lab Ltd Recovery of n-(7-2'-thienylacetamidoceph-3-em-3-ylmethyl) pyridinium - 4-carboxylate from an acid addition salt thereof
US3449338A (en) * 1968-11-04 1969-06-10 Lilly Co Eli Cephalosporin ca derivatives
GB1391437A (en) * 1971-04-07 1975-04-23 Glaxo Lab Ltd Preparation of antibiotic compounds
US3792047A (en) * 1971-12-07 1974-02-12 Glaxo Lab Ltd N-(7,2'-thienylacetamidoceph-3-em-3-ylmethyl)-3"or 4"-n-hydroxyloweralkylcarbamoyl-pyridinium-4-carboxylates
IL41723A (en) * 1972-03-17 1975-12-31 Ciba Geigy Ag N-phosphorus derivatives of amidines,their production and their use as pesticides
GB1467355A (en) * 1974-08-07 1977-03-16 Lepetit Spa Preparation of 6-aminopenicillanic acid 7-aminocephalospo ranic acid and derivatives thereof
JPS5283869A (en) * 1976-01-01 1977-07-13 Takeda Chem Ind Ltd Cephalosporin compounds
DK159154C (da) * 1975-02-24 1991-02-11 Takeda Chemical Industries Ltd Fremgangsmaade til fremstilling af cephalosporinderivater eller salte deraf
US4332798A (en) * 1978-12-29 1982-06-01 Fujisawa Pharmaceutical Co., Ltd. 7-Amino-thia-diazole oxyimino derivatives of cephem and cephem compounds
DE3019838A1 (de) * 1979-05-25 1980-12-04 Glaxo Group Ltd Zwischenprodukte zur verwendung bei der herstellung von cephalosporin-antibiotika
DE3069364D1 (en) * 1979-10-12 1984-11-08 Fujisawa Pharmaceutical Co Cephem compounds, processes for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
JPS5823698A (ja) 1983-02-12
EP0070706A2 (de) 1983-01-26
US4803267A (en) 1989-02-07
EP0070706B1 (de) 1987-12-23
US4563523A (en) 1986-01-07
AU557274B2 (en) 1986-12-18
EP0070706A3 (en) 1984-04-25
ZA825095B (en) 1983-05-25
AU8611982A (en) 1983-01-20
DE3277870D1 (en) 1988-02-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time