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ATE308611T1 - Phage verbunden an ein nukleus lokalisierungssignal - Google Patents

Phage verbunden an ein nukleus lokalisierungssignal

Info

Publication number
ATE308611T1
ATE308611T1 AT96943332T AT96943332T ATE308611T1 AT E308611 T1 ATE308611 T1 AT E308611T1 AT 96943332 T AT96943332 T AT 96943332T AT 96943332 T AT96943332 T AT 96943332T AT E308611 T1 ATE308611 T1 AT E308611T1
Authority
AT
Austria
Prior art keywords
phage
nuclear localization
localization signal
lambda phage
head
Prior art date
Application number
AT96943332T
Other languages
English (en)
Inventor
Mahito Nakanishi
Emi Nagoshi
Teruo Akuta
Katsuo Takeda
Mamoru Hasegawa
Original Assignee
Dnavec Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dnavec Research Inc filed Critical Dnavec Research Inc
Application granted granted Critical
Publication of ATE308611T1 publication Critical patent/ATE308611T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/10011—Details dsDNA Bacteriophages
    • C12N2795/10311—Siphoviridae
    • C12N2795/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2795/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Control Of Indicators Other Than Cathode Ray Tubes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Package Frames And Binding Bands (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT96943332T 1996-08-09 1996-12-27 Phage verbunden an ein nukleus lokalisierungssignal ATE308611T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP22778796 1996-08-09
PCT/JP1996/003861 WO1998006828A1 (fr) 1996-08-09 1996-12-27 Phage lie au signal de localisation nucleaire

Publications (1)

Publication Number Publication Date
ATE308611T1 true ATE308611T1 (de) 2005-11-15

Family

ID=16866385

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96943332T ATE308611T1 (de) 1996-08-09 1996-12-27 Phage verbunden an ein nukleus lokalisierungssignal

Country Status (10)

Country Link
US (3) US6235521B1 (de)
EP (1) EP0962525B1 (de)
KR (1) KR100478429B1 (de)
CN (1) CN1114691C (de)
AT (1) ATE308611T1 (de)
AU (1) AU1209697A (de)
CA (1) CA2262529A1 (de)
DE (1) DE69635383T2 (de)
DK (1) DK0962525T3 (de)
WO (1) WO1998006828A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5880607A (en) * 1996-05-01 1999-03-09 Sun Microsystems, Inc. Clock distribution network with modular buffers
ATE308611T1 (de) * 1996-08-09 2005-11-15 Dnavec Research Inc Phage verbunden an ein nukleus lokalisierungssignal
US6740524B1 (en) * 1998-06-18 2004-05-25 Dnavec Research, Inc. Nucleic acid transfer phage
GB0103110D0 (en) * 2000-08-25 2001-03-28 Aventis Pharma Inc A membrane penetrating peptide encoded by a nuclear localization sequence from human period 1
WO2002070720A1 (en) * 2001-03-02 2002-09-12 Riken Cloning vectors and method for molecular cloning
IL145463A0 (en) * 2001-09-16 2002-06-30 Yissum Res Dev Co A packaging complementation cell-line for sv40 vectors
US7514530B2 (en) * 2004-04-26 2009-04-07 Centre National De La Recherche Scientifique Peptide carrier for delivering siRNA into mammalian cells
WO2007015704A2 (en) * 2004-10-29 2007-02-08 University Of Rochester Modified bacteriophage vectors and uses thereof
EP2036980A1 (de) * 2007-09-14 2009-03-18 Gruber, Jens Herabregulation der Genexpression mittels Nukleinsäure-beladener virusähnlicher Partikel
CN104531857A (zh) * 2014-12-19 2015-04-22 安特诺生物医药（厦门）有限公司 一种装甲pd-1基因的rna标准物质及其应用
WO2024091578A2 (en) * 2022-10-27 2024-05-02 Seawolf Therapeutics, Inc. Nuclear targeted dna delivery and compositions for use in practicing the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9213601D0 (en) * 1992-06-26 1992-08-12 Mastico Robert A Protein based delivery system
US5627024A (en) 1994-08-05 1997-05-06 The Scripps Research Institute Lambdoid bacteriophage vectors for expression and display of foreign proteins
AU3737297A (en) * 1996-08-05 1998-02-25 Brigham And Women's Hospital Bacteriophage-mediated gene therapy
ATE308611T1 (de) * 1996-08-09 2005-11-15 Dnavec Research Inc Phage verbunden an ein nukleus lokalisierungssignal

Also Published As

Publication number Publication date
DK0962525T3 (da) 2006-03-20
WO1998006828A1 (fr) 1998-02-19
EP0962525A4 (de) 2001-12-05
CA2262529A1 (en) 1998-02-19
KR20000029889A (ko) 2000-05-25
US6759231B2 (en) 2004-07-06
AU1209697A (en) 1998-03-06
DE69635383T2 (de) 2006-08-03
US6235521B1 (en) 2001-05-22
CN1114691C (zh) 2003-07-16
DE69635383D1 (de) 2005-12-08
EP0962525A1 (de) 1999-12-08
CN1234832A (zh) 1999-11-10
US6300120B1 (en) 2001-10-09
KR100478429B1 (ko) 2005-03-24
US20020042135A1 (en) 2002-04-11
EP0962525B1 (de) 2005-11-02

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