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ATE300286T1 - Gastroretentive pharmazeutische dosierungsformen mit gesteuerten abgaben - Google Patents

Gastroretentive pharmazeutische dosierungsformen mit gesteuerten abgaben

Info

Publication number
ATE300286T1
ATE300286T1 AT00978993T AT00978993T ATE300286T1 AT E300286 T1 ATE300286 T1 AT E300286T1 AT 00978993 T AT00978993 T AT 00978993T AT 00978993 T AT00978993 T AT 00978993T AT E300286 T1 ATE300286 T1 AT E300286T1
Authority
AT
Austria
Prior art keywords
polymers
dosage forms
pharmaceutical dosage
stomach
mixtures
Prior art date
Application number
AT00978993T
Other languages
English (en)
Inventor
Michael Friedman
Eytan Klausner
Eran Lavy
Amnon Hoffman
Original Assignee
Yissum Res Dev Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yissum Res Dev Co filed Critical Yissum Res Dev Co
Application granted granted Critical
Publication of ATE300286T1 publication Critical patent/ATE300286T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT00978993T 1999-11-29 2000-11-20 Gastroretentive pharmazeutische dosierungsformen mit gesteuerten abgaben ATE300286T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13319699A IL133196A0 (en) 1999-11-29 1999-11-29 Gastroretentive controlled release pharmaceutical dosage forms
PCT/IL2000/000774 WO2001037812A2 (en) 1999-11-29 2000-11-20 Gastroretentive controlled release pharmaceutical dosage forms

Publications (1)

Publication Number Publication Date
ATE300286T1 true ATE300286T1 (de) 2005-08-15

Family

ID=11073546

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00978993T ATE300286T1 (de) 1999-11-29 2000-11-20 Gastroretentive pharmazeutische dosierungsformen mit gesteuerten abgaben

Country Status (12)

Country Link
US (1) US6685962B2 (de)
EP (1) EP1235557B1 (de)
JP (1) JP4679020B2 (de)
AT (1) ATE300286T1 (de)
AU (1) AU783062B2 (de)
CA (1) CA2392361C (de)
DE (1) DE60021604T2 (de)
ES (1) ES2243327T3 (de)
IL (2) IL133196A0 (de)
RU (1) RU2002114348A (de)
WO (1) WO2001037812A2 (de)
ZA (1) ZA200204268B (de)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040219186A1 (en) * 2001-08-16 2004-11-04 Ayres James W. Expandable gastric retention device
TWI312285B (en) * 2001-10-25 2009-07-21 Depomed Inc Methods of treatment using a gastric retained gabapentin dosage
AUPR951501A0 (en) * 2001-12-14 2002-01-24 Smart Drug Systems Inc Modified sustained release pharmaceutical system
AU2003299838A1 (en) 2002-12-19 2004-07-14 Polymorfix, Inc. Ingestible formulations for transient, noninvasive reduction of gastric volume
US7554452B2 (en) * 2003-07-18 2009-06-30 Cary Cole Ingestible tracking and locating device
CA2542512A1 (en) * 2003-09-04 2005-03-17 Nathan Ravi Hydrogel nanocompsites for ophthalmic applications
WO2005030179A1 (en) * 2003-09-29 2005-04-07 Cj Corporation Sustained-release formulations
CA2549195A1 (en) * 2003-12-09 2005-06-23 Spherics, Inc. Bioadhesive polymers with catechol functionality
US20080089933A1 (en) 2006-10-16 2008-04-17 Amir Alon Device and method for reducing calorie intake
US20050196355A1 (en) * 2004-03-03 2005-09-08 Constantine Georgiades Film products having controlled disintegration properties
US8007827B2 (en) * 2004-04-02 2011-08-30 Impax Laboratories, Inc. Pharmaceutical dosage forms having immediate release and/or controlled release properties
PL1750862T3 (pl) 2004-06-04 2011-06-30 Teva Pharma Kompozycja farmaceutyczna zawierająca irbesartan
US20080311191A1 (en) * 2004-08-27 2008-12-18 Avinash Nangia Multi-Layer Tablets and Bioadhesive Dosage Forms
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
US8481565B2 (en) * 2004-12-27 2013-07-09 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
US20060280789A1 (en) * 2004-12-27 2006-12-14 Eisai Research Institute Sustained release formulations
IL166183A0 (en) * 2005-01-06 2006-01-15 Yissum Res Dev Co Novel diagnostic and imaging techniques of the gi tract
KR100822519B1 (ko) * 2005-02-15 2008-04-16 주식회사종근당 위장 내에서 제어방출되는 단일 매트릭스 정제
WO2007041079A2 (en) * 2005-09-30 2007-04-12 Alza Corporation Banded controlled release nanoparticle active agent formulation dosage forms and methods
US20070092565A1 (en) * 2005-10-25 2007-04-26 Pharmascience Inc. Gastric retention drug delivery system
ES2559678T3 (es) 2006-01-18 2016-02-15 Intec Pharma Ltd. Método para formar dispositivos de suministro para la vía oral de un agente
US20090304768A1 (en) * 2006-02-15 2009-12-10 Intec Pharma Ltd Gastro-Retentive System for the Delivery of Macromolecules
US20100226855A1 (en) * 2006-03-02 2010-09-09 Spherics, Inc. Rate-Controlled Oral Dosage Formulations
AR062659A1 (es) * 2006-09-08 2008-11-26 Drug Tech Corp Composicion de liberacion sostenida de levodopa y metodo para su uso
AU2007336731B2 (en) 2006-12-22 2013-08-29 Ironwood Pharmaceuticals, Inc. Compositions comprising bile acid sequestrants for treating esophageal disorders
WO2008115597A2 (en) * 2007-03-21 2008-09-25 Cytologic, Inc. Cytokine muteins and methods for enhancing immune responses in mammals
EP2192946B1 (de) 2007-09-25 2022-09-14 Otsuka Pharmaceutical Co., Ltd. Körperinterne vorrichtung mit virtueller dipol-signal-verstärkung
ES2463774T3 (es) 2007-11-12 2014-05-29 Pharmaceutics International, Inc. Complejos trimoleculares y su uso en sistemas de administración de fármacos
US8771730B2 (en) * 2008-04-18 2014-07-08 Intec Pharma Ltd. Carbidopa/Levodopa gastroretentive drug delivery
WO2009136493A1 (ja) * 2008-05-08 2009-11-12 パナソニック株式会社 不揮発性記憶素子、及び、不揮発性記憶素子又は不揮発性記憶装置の製造方法
US8287902B2 (en) * 2008-07-23 2012-10-16 Rainbow Medical Ltd. Enhanced-diffusion capsule
WO2010064139A2 (en) * 2008-12-04 2010-06-10 Intec Pharma Ltd. Zaleplon gastroretentive drug delivery system
US9901551B2 (en) 2009-04-20 2018-02-27 Ambra Bioscience Llc Chemosensory receptor ligand-based therapies
AR076341A1 (es) 2009-04-20 2011-06-01 Elcelyx Therapeutics Inc Terapias basadas en ligados de receptores quimiosensoriales. metodo de tratamiento. composicion
US8828953B2 (en) * 2009-04-20 2014-09-09 NaZura BioHealth, Inc. Chemosensory receptor ligand-based therapies
US8414559B2 (en) * 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
US20110066175A1 (en) * 2009-05-07 2011-03-17 Rainbow Medical Ltd. Gastric anchor
US20100286628A1 (en) * 2009-05-07 2010-11-11 Rainbow Medical Ltd Gastric anchor
US20120321706A1 (en) * 2009-10-19 2012-12-20 Intec Pharma Ltd. Novel gastroretentive dosage forms of poorly soluble drugs
CN102695500A (zh) 2009-11-09 2012-09-26 聚光灯技术合伙有限责任公司 多糖基水凝胶
US8795727B2 (en) 2009-11-09 2014-08-05 Spotlight Technology Partners Llc Fragmented hydrogels
DK2513200T3 (en) 2009-12-18 2018-06-14 Coloplast As A biomaterial
WO2011073968A1 (en) * 2009-12-18 2011-06-23 Vysera Biomedical Limited A drug delivery system
EP2544666A2 (de) 2010-03-09 2013-01-16 Council of Scientific and Industrial Research Gastroretentive retard-zusammensetzung eines therapeutikums
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
KR20140114736A (ko) 2010-10-19 2014-09-29 엘셀릭스 테라퓨틱스 인코포레이티드 화학감각 수용체 리간드-기반 요법
SI2661266T1 (sl) 2011-01-07 2021-01-29 Anji Pharma (Us) Llc Terapije, na osnovi kemosenzoričnih receptorskih ligandov
US8722066B2 (en) 2011-03-29 2014-05-13 Primigenia, LLC Devices and methods for weight control and weight loss
US20130143867A1 (en) 2011-12-02 2013-06-06 Sychroneuron Inc. Acamprosate formulations, methods of using the same, and combinations comprising the same
WO2013158928A2 (en) 2012-04-18 2013-10-24 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies
WO2014039951A1 (en) 2012-09-10 2014-03-13 Novartis Ag Enteral pharmaceutical compositions
US9682081B2 (en) 2013-04-25 2017-06-20 Sun Pharmaceutical Industries Limited Pharmaceutical gastro-retentive solid oral dosage form of nilotinib
CN105431144A (zh) 2013-06-05 2016-03-23 思康脑侒股份有限公司 阿坎酸制剂、使用阿坎酸制剂的方法以及包含阿坎酸制剂的组合
CN105828809B (zh) * 2013-12-20 2019-10-29 费森尤斯卡比德国有限公司 包含脂质和活性药剂的具有聚合物涂层的微胶囊
RU2016151697A (ru) 2014-06-02 2018-07-10 Тева Фармасьютикал Индастриз Лтд. Расправляемая удерживаемая в желудке лекарственная форма
US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
SG10201912100SA (en) 2014-06-11 2020-02-27 Massachusetts Inst Technology Residence structures and related methods
US9492396B2 (en) 2014-07-15 2016-11-15 Yossi Gross Enhanced drug delivery pill
CN113081991B (zh) * 2015-06-03 2022-07-15 南京三迭纪医药科技有限公司 药品剂型及其使用
EP3302442B1 (de) * 2015-06-03 2024-10-16 Triastek, Inc. Darreichungsform und verwendung davon
WO2016205270A1 (en) 2015-06-17 2016-12-22 Biogen Ma Inc. Dimethyl fumarate particles and pharmaceutical compositions thereof
CN108472249A (zh) 2015-10-23 2018-08-31 林德拉有限公司 用于治疗剂缓释的胃驻留系统及其使用方法
US11129798B2 (en) 2016-08-19 2021-09-28 Aron H. Blaesi Fibrous dosage form
EP3368010A4 (de) * 2015-10-26 2019-04-10 Blaesi, Aron H. Feste dosierungsform für sofortige wirkstofffreisetzung sowie vorrichtung und verfahren zur herstellung davon
US11478427B2 (en) * 2015-10-26 2022-10-25 Aron H. Blaesi Dosage form comprising structural framework of two-dimensional elements
JP2018536007A (ja) * 2015-12-01 2018-12-06 クレキシオ バイオサイエンシーズ エルティーディー. 胃保持性装置
WO2017093976A1 (en) * 2015-12-02 2017-06-08 Teva Pharmaceutical Industries Ltd. Device for preparing gastroretentive dosage forms
US11992552B2 (en) 2015-12-08 2024-05-28 Lyndra Therapeutics, Inc. Geometric configurations for gastric residence systems
CN109310653A (zh) 2016-03-17 2019-02-05 硫创治疗公司 用于控制释放半胱胺和系统治疗半胱胺敏感性病症的组合物
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
AU2017268840B2 (en) 2016-05-27 2022-02-10 Lyndra Therapeutics, Inc. Materials architecture for gastric residence systems
KR20190026799A (ko) * 2016-07-11 2019-03-13 인텍 파마 리미티드 경구 위체류 제형 및 이의 용도
JP2019532947A (ja) 2016-09-30 2019-11-14 リンドラ,インコーポレイティド アダマンタン系薬物の持続的送達のための胃内滞留システム
ES2966736T3 (es) 2016-12-02 2024-04-24 Clexio Biosciences Ltd Sistema de residencia gástrica
CA3051614A1 (en) 2017-01-26 2018-08-02 Triastek, Inc. Dosage forms of controlled release at specific gastrointestinal sites
AU2018279853B2 (en) 2017-06-09 2024-07-04 Lyndra Therapeutics, Inc. Gastric residence systems with release rate-modulating films
EP3684418A4 (de) 2017-09-20 2021-06-16 Thiogenesis Therapeutics, Inc. Verfahren zur behandlung von cysteaminempfindlichen erkrankungen
US11547839B2 (en) 2017-12-04 2023-01-10 Clexio Biosciences Ltd. Long acting gastric residence system
CN116270513A (zh) 2018-01-09 2023-06-23 南京三迭纪医药科技有限公司 一种包含固定剂量adhd非兴奋剂和adhd兴奋剂的复方口服药物剂型
WO2019223753A1 (zh) 2018-05-23 2019-11-28 上海汉都医药科技有限公司 活性药物成分的控释系统及其制备方法
CN114191307A (zh) 2020-09-17 2022-03-18 上海汉都医药科技有限公司 一种口腔滞留装置及其制备方法
US11911513B2 (en) 2018-05-23 2024-02-27 Shanghai Wd Pharmaceutical Co., Ltd Controlled-release system of active pharmaceutical ingredient and preparation method therefor
US10675248B2 (en) 2018-08-14 2020-06-09 Alma Therapeutics Ltd. Expandable pill
AU2021396978A1 (en) 2020-12-08 2023-02-23 Ruminant Biotech Corp Limited Improvements to devices and methods for delivery of substances to animals

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3574820A (en) 1968-01-08 1971-04-13 Upjohn Co Medicinal dosage forms of unpolymerized thiolated gelatin with a cross-linking accelerating agent providing slowly released medication from a swollen matrix
US4207890A (en) 1977-01-04 1980-06-17 Mcneilab, Inc. Drug-dispensing device and method
US4434153A (en) 1982-03-22 1984-02-28 Alza Corporation Drug delivery system comprising a reservoir containing a plurality of tiny pills
US4735804A (en) 1985-05-10 1988-04-05 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US4767627A (en) 1985-05-29 1988-08-30 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US4758436A (en) 1985-05-29 1988-07-19 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
US5002772A (en) 1988-05-31 1991-03-26 Pfizer Inc. Gastric retention system for controlled drug release
US5217712A (en) 1989-09-20 1993-06-08 Merck & Co., Inc. Bioerodible thermoset elastomers
US5047464A (en) 1989-09-20 1991-09-10 Merck & Co., Inc. Bioerodible thermoset elastomers
IT1265240B1 (it) * 1993-11-30 1996-10-31 Ekita Investments Nv Compressa farmaceutica a rilascio controllato, di forma lenticolare
DE4406424A1 (de) 1994-02-28 1995-08-31 Bayer Ag Expandierbare Arzneiformen
US5840332A (en) * 1996-01-18 1998-11-24 Perio Products Ltd. Gastrointestinal drug delivery system

Also Published As

Publication number Publication date
US6685962B2 (en) 2004-02-03
CA2392361C (en) 2010-01-19
ZA200204268B (en) 2003-08-28
IL149853A (en) 2006-12-31
CA2392361A1 (en) 2001-05-31
JP4679020B2 (ja) 2011-04-27
DE60021604D1 (de) 2005-09-01
US20030021845A1 (en) 2003-01-30
WO2001037812A2 (en) 2001-05-31
JP2003514845A (ja) 2003-04-22
RU2002114348A (ru) 2004-01-10
DE60021604T2 (de) 2006-06-01
EP1235557A2 (de) 2002-09-04
AU783062B2 (en) 2005-09-22
AU1647701A (en) 2001-06-04
EP1235557B1 (de) 2005-07-27
IL133196A0 (en) 2001-03-19
ES2243327T3 (es) 2005-12-01
WO2001037812A3 (en) 2002-02-21

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