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ATE381532T1 - Verfahren zur herstellung von gabapentin - Google Patents

Verfahren zur herstellung von gabapentin

Info

Publication number
ATE381532T1
ATE381532T1 AT05015675T AT05015675T ATE381532T1 AT E381532 T1 ATE381532 T1 AT E381532T1 AT 05015675 T AT05015675 T AT 05015675T AT 05015675 T AT05015675 T AT 05015675T AT E381532 T1 ATE381532 T1 AT E381532T1
Authority
AT
Austria
Prior art keywords
gabapentin
desilylation
producing gabapentin
producing
silylation
Prior art date
Application number
AT05015675T
Other languages
English (en)
Inventor
Rafael Garcia
Johannes Ludescher
Jordi Rifa
Jose Diago
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of ATE381532T1 publication Critical patent/ATE381532T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT05015675T 2004-07-20 2005-07-19 Verfahren zur herstellung von gabapentin ATE381532T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0416228.5A GB0416228D0 (en) 2004-07-20 2004-07-20 Process for the preparation of gabapentin

Publications (1)

Publication Number Publication Date
ATE381532T1 true ATE381532T1 (de) 2008-01-15

Family

ID=32922525

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05015675T ATE381532T1 (de) 2004-07-20 2005-07-19 Verfahren zur herstellung von gabapentin

Country Status (6)

Country Link
US (1) US7098362B2 (de)
EP (1) EP1619181B1 (de)
AT (1) ATE381532T1 (de)
DE (1) DE602005003878D1 (de)
ES (1) ES2296012T3 (de)
GB (1) GB0416228D0 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2677096A1 (en) 2007-01-31 2008-08-07 Vertex Pharmaceuticals Incorporated Kinase inhibitors
US8569337B2 (en) 2008-07-23 2013-10-29 Vertex Pharmaceuticals Incorporated Tri-cyclic pyrazolopyridine kinase inhibitors
JP2011530527A (ja) 2008-08-06 2011-12-22 バーテックス ファーマシューティカルズ インコーポレイテッド アミノピリジンキナーゼ阻害剤
MX2012008643A (es) 2010-01-27 2013-02-26 Vertex Pharma Inhibidores de cinasas de pirazolopiridinas.

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2460891C2 (de) 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4894476A (en) 1988-05-02 1990-01-16 Warner-Lambert Company Gabapentin monohydrate and a process for producing the same
US5319135A (en) 1989-08-25 1994-06-07 Warner-Lambert Company Process for cyclic amino acid anticonvulsant compounds
DE3928182A1 (de) 1989-08-25 1991-02-28 Goedecke Ag Verfahren zur herstellung von gabapentin
AU633612B2 (en) 1989-08-25 1993-02-04 Warner-Lambert Company Improved process for cyclic amino acid anticonvulsant compounds
FI905584A (fi) 1989-11-16 1991-05-17 Lonza Ag Foerfarande foer framstaellning av 1-(aminometyl)cyklohexanaettikssyra.
IL119890A (en) 1996-12-24 2002-03-10 Teva Pharma Gabapentin form iii and preparation of gabapentin form ii
WO1999018063A2 (en) 1997-10-07 1999-04-15 Warner-Lambert Company Process for preparing a cyclic amino acid anticonvulsant compound
ITMI981535A1 (it) 1998-07-03 2000-01-03 Zambon Spa Processo per la preparazione di gabapentina
ES2164527B1 (es) 1999-04-26 2003-04-01 Medichen S A Procedimiento de obtencion de gabapentina de calidad farmaceutica.
IT1319234B1 (it) 2000-10-23 2003-09-26 Zambon Spa Processo di preparazione di gabapentina.
WO2002074727A1 (en) 2001-03-16 2002-09-26 Solchem Italiana S.P.A. A process for the preparation of cyclic amino acids
ITMI20011132A1 (it) 2001-05-29 2002-11-29 Procos Spa Procedimento per la preparazione dell'acido 1-amminometil-1-cicloesanacetico
WO2003070683A1 (en) 2002-02-22 2003-08-28 Shasun Chemicals And Drugs Limited Preparation of new mineral acid addition salts of gabapentin
AU2003262383A1 (en) 2002-04-16 2003-11-03 Taro Pharmaceutical Industries Ltd. Process for preparing gabapentin

Also Published As

Publication number Publication date
EP1619181A1 (de) 2006-01-25
EP1619181B1 (de) 2007-12-19
US7098362B2 (en) 2006-08-29
GB0416228D0 (en) 2004-08-25
DE602005003878D1 (de) 2008-01-31
US20060020034A1 (en) 2006-01-26
ES2296012T3 (es) 2008-04-16

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Legal Events

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