[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

ATE342918T1 - Genomische sequenz des 5-lipoxygenase- aktivierenden proteins (flap), polymorphische marker und ihre anwendung in der diagnose von asthma - Google Patents

Genomische sequenz des 5-lipoxygenase- aktivierenden proteins (flap), polymorphische marker und ihre anwendung in der diagnose von asthma

Info

Publication number
ATE342918T1
ATE342918T1 AT99913538T AT99913538T ATE342918T1 AT E342918 T1 ATE342918 T1 AT E342918T1 AT 99913538 T AT99913538 T AT 99913538T AT 99913538 T AT99913538 T AT 99913538T AT E342918 T1 ATE342918 T1 AT E342918T1
Authority
AT
Austria
Prior art keywords
asthma
diagnosis
flap
genomic sequence
lipoxygenase
Prior art date
Application number
AT99913538T
Other languages
English (en)
Inventor
Marta Blumenfeld
Ilya Chumakov
Lydie Bougueleret
Original Assignee
Serono Genetics Inst Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27374096&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE342918(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Serono Genetics Inst Sa filed Critical Serono Genetics Inst Sa
Application granted granted Critical
Publication of ATE342918T1 publication Critical patent/ATE342918T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702Regulators; Modulating activity
    • C07K14/4705Regulators; Modulating activity stimulating, promoting or activating activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6827Hybridisation assays for detection of mutation or polymorphism
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
AT99913538T 1998-04-15 1999-04-15 Genomische sequenz des 5-lipoxygenase- aktivierenden proteins (flap), polymorphische marker und ihre anwendung in der diagnose von asthma ATE342918T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8189398P 1998-04-15 1998-04-15
US9131498P 1998-06-30 1998-06-30
US12340699P 1999-03-08 1999-03-08

Publications (1)

Publication Number Publication Date
ATE342918T1 true ATE342918T1 (de) 2006-11-15

Family

ID=27374096

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99913538T ATE342918T1 (de) 1998-04-15 1999-04-15 Genomische sequenz des 5-lipoxygenase- aktivierenden proteins (flap), polymorphische marker und ihre anwendung in der diagnose von asthma

Country Status (11)

Country Link
US (4) US6531279B1 (de)
EP (1) EP1071710B2 (de)
JP (1) JP4472173B2 (de)
AT (1) ATE342918T1 (de)
AU (1) AU768721B2 (de)
CA (1) CA2321226C (de)
DE (1) DE69933661T3 (de)
DK (1) DK1071710T4 (de)
ES (1) ES2272061T5 (de)
PT (1) PT1071710E (de)
WO (1) WO1999052942A2 (de)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999052942A2 (en) * 1998-04-15 1999-10-21 Genset Genomic sequence of the 5-lipoxygenase-activating protein (flap), polymorphic markers thereof and methods for detection of asthma
US6537751B1 (en) * 1998-04-21 2003-03-25 Genset S.A. Biallelic markers for use in constructing a high density disequilibrium map of the human genome
US6986987B1 (en) * 1998-07-24 2006-01-17 The Uab Research Foundation Genetic polymorphism in the receptor for IgA
AU779411B2 (en) 1999-02-12 2005-01-20 Serono Genetics Institute S.A. Biallelic markers derived from genomic regions carrying genes involved in arachidonic acid metabolism
KR100679349B1 (ko) * 1999-11-30 2007-02-07 아사히비루 가부시키가이샤 하면 맥주효모의 응집성 판정방법
US20020077775A1 (en) * 2000-05-25 2002-06-20 Schork Nicholas J. Methods of DNA marker-based genetic analysis using estimated haplotype frequencies and uses thereof
US7205146B1 (en) * 2000-06-14 2007-04-17 Oscient Pharmaceuticals Corporation Nucleotide and amino acid sequences relating to respiratory diseases and obesity
CN1329012A (zh) * 2000-06-21 2002-01-02 上海博德基因开发有限公司 一种新的多肽——烟酰胺腺嘌呤脱氧二核苷酸依赖性白三烯b412-羟基脱氢酶36和编码这种多肽的多核甘酸
EP1354061A2 (de) * 2000-09-08 2003-10-22 Iowa State University Research Foundation, Inc. Neue prkag3 allele und verwendungen derselben als genetische marker für reproduktivität- und fleisch-qualitätsmerkmale
DE01992795T1 (de) * 2000-10-31 2004-12-16 Michel Alphonse Julien Georges Marker-unterstützte auswahl von rindvieh für verbesserte milchproduktion unter verwendung des diacylglycerin-acyltransferase-gens dgat1
KR101651391B1 (ko) * 2000-12-12 2016-08-25 세키스이 메디칼 가부시키가이샤 Ugt1a1 효소에 의해 그 자체 또는 중간 대사물이 대사되는 화합물의 투여에 따른 부작용 발현 리스크를 예측하는 방법
FI114483B (fi) * 2001-02-20 2004-10-29 Jurilab Ltd Oy Menetelmä kohonneen verenpaineen riskin osoittamiseksi ja sen käytöt
US7271240B2 (en) 2001-03-14 2007-09-18 Agensys, Inc. 125P5C8: a tissue specific protein highly expressed in various cancers
AU785425B2 (en) 2001-03-30 2007-05-17 Genetic Technologies Limited Methods of genomic analysis
US7115726B2 (en) * 2001-03-30 2006-10-03 Perlegen Sciences, Inc. Haplotype structures of chromosome 21
ATE335851T1 (de) * 2001-04-19 2006-09-15 Hubit Genomix Inc Verfahren zur abschätzung des diplotyps aus dem genotyp eines individuums
CA2495529C (en) * 2001-10-01 2009-05-19 Mount Sinai School Of Medicine Of New York University Noonan syndrome gene
TWI329105B (en) 2002-02-01 2010-08-21 Rigel Pharmaceuticals Inc 2,4-pyrimidinediamine compounds and their uses
WO2003076573A2 (en) * 2002-03-04 2003-09-18 The Texas A & M University System Quantitative trait loci and somatostatin
US7579147B2 (en) * 2002-05-07 2009-08-25 Wake Forest University Health Sciences Mutations in the macrophage scavenger receptor 1 gene alter risk of prostate cancer, asthma, and cardiovascular disease
AU2003243151A1 (en) * 2002-08-16 2004-03-03 Agensys, Inc. Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer
WO2004024952A1 (en) * 2002-08-30 2004-03-25 Oncotherapy Science, Inc. Method of diagnosing ovarian endometriosis
AU2003290527A1 (en) * 2002-10-17 2004-05-04 Decode Genetics Ehf. Susceptibility gene for myocardial infarction
US7851486B2 (en) 2002-10-17 2010-12-14 Decode Genetics Ehf. Susceptibility gene for myocardial infarction, stroke, and PAOD; methods of treatment
WO2004035741A2 (en) * 2002-10-17 2004-04-29 Decode Genetics Ehf. Susceptibility gene for myocardial infarction; methods of treatment
US20060019269A1 (en) * 2002-10-17 2006-01-26 Decode Genetics, Inc. Susceptibility gene for myocardial infarction, stroke, and PAOD, methods of treatment
US20080293750A1 (en) * 2002-10-17 2008-11-27 Anna Helgadottir Susceptibility Gene for Myocardial Infarction, Stroke, Paod and Methods of Treatment
US7507531B2 (en) * 2002-10-17 2009-03-24 Decode Genetics Chf. Use of 5-lipoxygenase activating protein (FLAP) gene to assess susceptibility for myocardial infarction
US20040146870A1 (en) * 2003-01-27 2004-07-29 Guochun Liao Systems and methods for predicting specific genetic loci that affect phenotypic traits
US7803538B2 (en) * 2003-06-20 2010-09-28 Aventis Pharma Sa Method for detecting Alzheimer's disease
CA2533377C (en) * 2003-07-30 2012-11-27 Rigel Pharmaceuticals, Inc. Methods of treating or preventing autoimmune diseases with 2,4-pyrimidinediamine compounds
US7335474B2 (en) 2003-09-12 2008-02-26 Perlegen Sciences, Inc. Methods and systems for identifying predisposition to the placebo effect
US20050272051A1 (en) * 2003-09-17 2005-12-08 Decode Genetics Ehf. Methods of preventing or treating recurrence of myocardial infarction
US8158362B2 (en) * 2005-03-30 2012-04-17 Decode Genetics Ehf. Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype
US20100216863A1 (en) * 2004-01-30 2010-08-26 Decode Genetics Ehf. Susceptibility Gene for Myocardial Infarction, Stroke, and PAOD; Methods of Treatment
JP2007315752A (ja) * 2004-08-16 2007-12-06 Ajinomoto Co Inc 肝線維化ステージの判定方法
US20070117775A1 (en) * 2005-10-31 2007-05-24 Rigel Pharmaceuticals, Inc. Compositions and Methods For Treating Inflammatory Disorders
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
US20080082359A1 (en) * 2006-09-29 2008-04-03 Searete Llc, A Limited Liability Corporation Of State Of Delaware Computational systems for biomedical data
US7853626B2 (en) * 2006-09-29 2010-12-14 The Invention Science Fund I, Llc Computational systems for biomedical data
US20080082367A1 (en) * 2006-09-29 2008-04-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems for biomedical data
US20080082584A1 (en) * 2006-09-29 2008-04-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems for biomedical data
US20080082583A1 (en) * 2006-09-29 2008-04-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems for biomedical data
US8122073B2 (en) * 2006-09-29 2012-02-21 The Invention Science Fund I Computational systems for biomedical data
US20080091730A1 (en) * 2006-09-29 2008-04-17 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems for biomedical data
US10546652B2 (en) * 2006-09-29 2020-01-28 Gearbox Llc Computational systems for biomedical data
US20080082364A1 (en) * 2006-09-29 2008-04-03 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems for biomedical data
US20080082271A1 (en) * 2006-09-29 2008-04-03 Searete Llc Computational systems for biomedical data
US10503872B2 (en) * 2006-09-29 2019-12-10 Gearbox Llc Computational systems for biomedical data
US20080109484A1 (en) * 2006-09-29 2008-05-08 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Computational systems for biomedical data
US20080082306A1 (en) * 2006-09-29 2008-04-03 Searete Llc Computational systems for biomedical data
US10068303B2 (en) * 2006-09-29 2018-09-04 Gearbox Llc Computational systems for biomedical data
US10095836B2 (en) * 2006-09-29 2018-10-09 Gearbox Llc Computational systems for biomedical data
JP2010511632A (ja) 2006-11-30 2010-04-15 アミラ ファーマシューティカルス,インコーポレーテッド 5−リポキシゲナーゼ活性化タンパク質インヒビターおよび一酸化窒素モジュレーターを含んでいる組成物および治療法
TW200920369A (en) * 2007-10-26 2009-05-16 Amira Pharmaceuticals Inc 5-lipoxygenase activating protein (flap) inhibitor
WO2009057640A1 (ja) * 2007-10-29 2009-05-07 Riken Brca1 関連タンパク質(brap)遺伝子内一塩基多型を用いた炎症性疾患の判定方法
WO2010068311A1 (en) 2008-05-23 2010-06-17 Amira Pharmaceuticals, Inc. 5-lipoxygenase-activating protein inhibitor
US8546431B2 (en) 2008-10-01 2013-10-01 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
US8568980B2 (en) * 2009-01-27 2013-10-29 Mount Sinai School Of Medicine Nucleic acids, methods and kits for the diagnosis of DYT6 primary torsion dystonia
EP2576834A4 (de) * 2010-05-26 2013-11-20 Philadelphia Children Hospital Zusammensetzungen und verfahren zur diagnose und behandlung des primären insulin-wachstumsfaktor-mangels und von idiopathischem kleinwuchs
KR102504750B1 (ko) 2010-09-29 2023-03-02 어젠시스 인코포레이티드 191p4d12 단백질에 결합하는 항체 약물 컨쥬게이트(adc)
EP2865756A1 (de) 2013-10-22 2015-04-29 Sylentis, S.A.U. siRNA und deren Verwendung in Verfahren und Zusammensetzungen zur Hemmung der Expression des FLAP-Gens
DK3102209T3 (da) 2014-02-04 2021-07-12 Bioscience Pharma Partners Llc Anvendelse af flap-hæmmere til at reducere neuroinflammationsmedieret læsion i centralnervesystemet
CN115925864A (zh) * 2015-12-11 2023-04-07 国立大学法人高知大学 胰腺癌和胰管内乳头状粘液性肿瘤的标志物
KR102527520B1 (ko) * 2020-09-16 2023-05-03 순천대학교 산학협력단 직업성 천식 진단용 조성물 및 이를 이용한 직업성 천식 진단방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2032253C (en) * 1989-12-15 2000-11-28 John W. Gillard 5-lipoxygenase activating protein
US5182367A (en) * 1990-11-30 1993-01-26 Merck & Co., Inc. 5-lipoxygenase activating protein
US5578443A (en) * 1991-03-06 1996-11-26 Regents Of The University Of Minnesota DNA sequence-based HLA typing method
AU690131B2 (en) * 1993-07-26 1998-04-23 Variagenics, Inc. Inhibitors of alternative alleles of genes as a basis for cancer therapeutic agents
US5696076A (en) 1994-06-22 1997-12-09 Human Genome Sciences, Inc. 5-lipoxygenase-activating protein II
AU2927797A (en) * 1996-05-06 1997-11-26 Brigham And Women's Hospital 5-lipoxygenase gene polymorphisms and their use in classifying patients
WO1999052942A2 (en) * 1998-04-15 1999-10-21 Genset Genomic sequence of the 5-lipoxygenase-activating protein (flap), polymorphic markers thereof and methods for detection of asthma

Also Published As

Publication number Publication date
EP1071710B1 (de) 2006-10-18
US20070003971A1 (en) 2007-01-04
US6531279B1 (en) 2003-03-11
US7494777B2 (en) 2009-02-24
ES2272061T5 (es) 2012-02-24
DK1071710T3 (da) 2007-02-19
DE69933661D1 (de) 2006-11-30
ES2272061T3 (es) 2007-04-16
WO1999052942A2 (en) 1999-10-21
US20050196752A1 (en) 2005-09-08
US20090155806A1 (en) 2009-06-18
EP1071710B2 (de) 2011-11-02
WO1999052942A3 (en) 2000-02-03
DE69933661T3 (de) 2012-01-26
DE69933661T2 (de) 2007-08-23
US7118869B2 (en) 2006-10-10
CA2321226C (en) 2011-06-07
JP4472173B2 (ja) 2010-06-02
US7838241B2 (en) 2010-11-23
EP1071710A2 (de) 2001-01-31
AU768721B2 (en) 2004-01-08
PT1071710E (pt) 2007-01-31
JP2002511242A (ja) 2002-04-16
AU3164499A (en) 1999-11-01
DK1071710T4 (da) 2011-12-12
CA2321226A1 (en) 1999-10-21

Similar Documents

Publication Publication Date Title
ATE342918T1 (de) Genomische sequenz des 5-lipoxygenase- aktivierenden proteins (flap), polymorphische marker und ihre anwendung in der diagnose von asthma
WO2001075454A3 (en) Diagnosis and treatment of alzheimer's disease
WO2002059604A3 (en) Diagnosis and treatment of multiple sclerosis
WO1999049807A3 (en) A device and method for performing a biological modification of a fluid
WO2004052175A3 (en) Methods for rapid identification of pathogens in humans and animals
SG141418A1 (en) Method for the detection of gene transcripts in blood and uses thereof
ATE266723T1 (de) Lösung die chaotropische mittel enthält und verwendung dieser lösung in verfahren zur isolierung von dna, rna und proteinen
WO2004060278A3 (en) Methods for rapid identification of pathogens in humans and animals
WO2003048300A3 (en) Methods of identifying cellular target molecules
BR9812783A (pt) "sistemas de detecção para o registro de interações e as relações funcionais de proteìnas"
BR0014150A (pt) Diagnósticos e terapêuticos para osteoporose
FR2806739B1 (fr) Genes impliques dans les maladies inflammatoires de l'intestin et leur utilisation
WO2001025791A3 (en) Prostate cancer marker proteins
ATE392620T1 (de) Nachweismittel von patologischen veränderungen des proteins app und ihre verwendungen
WO2000056924A3 (en) Genomic sequence of the purh gene and purh-related biallelic markers
WO2001062785A3 (en) Protein and gene and their use for diagnosis and treatment of schizophrenia
WO1999061614A3 (en) Human socs proteins
WO2001063294A3 (en) Diagnosis of bipolar affective disorder (bad) and unipolar depression
WO2003099107A3 (en) Methods and kits for the detection of renal cell carcinoma in a biological fluid of a patient
DE69939623D1 (de) Polymorphe marker von prostatakarzinom tumorantigen-1 (pcta-1)
DE60101305D1 (de) Dpi-6, ein therapeutischer biomarker in neurologischen krankheiten
WO2004039312A3 (en) Optineurin and glaucoma
WO2001083524A3 (en) Rna metabolism proteins
DE60144027D1 (de) 5t4 rna in plasma und serum als marker für neoplastische erkrankungen
WO2003001212A3 (en) A method for diagnosing a person having multiple sclerosis

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1071710

Country of ref document: EP

EEFA Change of the company name