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ATE299699T1 - Arzneimittel enthaltend oxaprozin natriumsalz, kaliumsalz, oder tris(hydroxymethyl)aminomethansalz - Google Patents

Arzneimittel enthaltend oxaprozin natriumsalz, kaliumsalz, oder tris(hydroxymethyl)aminomethansalz

Info

Publication number
ATE299699T1
ATE299699T1 AT97925466T AT97925466T ATE299699T1 AT E299699 T1 ATE299699 T1 AT E299699T1 AT 97925466 T AT97925466 T AT 97925466T AT 97925466 T AT97925466 T AT 97925466T AT E299699 T1 ATE299699 T1 AT E299699T1
Authority
AT
Austria
Prior art keywords
salt
tris
hydroxymethyl
products containing
aminomethane
Prior art date
Application number
AT97925466T
Other languages
English (en)
Inventor
Mark E Adams
Subhash Desai
Aziz Karim
Kalidas Paul
Douglas J Schaaf
David J Zold
Original Assignee
Searle Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle Llc filed Critical Searle Llc
Application granted granted Critical
Publication of ATE299699T1 publication Critical patent/ATE299699T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/421—1,3-Oxazoles, e.g. pemoline, trimethadione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Steroid Compounds (AREA)
AT97925466T 1996-05-20 1997-05-14 Arzneimittel enthaltend oxaprozin natriumsalz, kaliumsalz, oder tris(hydroxymethyl)aminomethansalz ATE299699T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1903396P 1996-05-20 1996-05-20
PCT/US1997/007637 WO1997044022A1 (en) 1996-05-20 1997-05-14 Potassium, sodium and tris oxaprozin salt pharmaceutical formulations

Publications (1)

Publication Number Publication Date
ATE299699T1 true ATE299699T1 (de) 2005-08-15

Family

ID=21791076

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97925466T ATE299699T1 (de) 1996-05-20 1997-05-14 Arzneimittel enthaltend oxaprozin natriumsalz, kaliumsalz, oder tris(hydroxymethyl)aminomethansalz

Country Status (20)

Country Link
US (1) US6030643A (de)
EP (1) EP0901372B1 (de)
JP (1) JP4185974B2 (de)
KR (1) KR20000015865A (de)
CN (1) CN1129429C (de)
AT (1) ATE299699T1 (de)
AU (1) AU718030B2 (de)
BR (1) BR9710448A (de)
CA (1) CA2255064C (de)
CZ (1) CZ370298A3 (de)
DE (1) DE69733752T2 (de)
ES (1) ES2248850T3 (de)
IL (1) IL126998A (de)
NO (1) NO985414L (de)
NZ (1) NZ332861A (de)
PL (1) PL330145A1 (de)
RU (1) RU2197244C2 (de)
TW (1) TW586929B (de)
WO (1) WO1997044022A1 (de)
ZA (1) ZA974366B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1233755E (pt) * 1999-09-29 2007-07-30 Scherer Technologies Inc R P Granulações de celulose hidrolisada de sais de fármacos
US6497157B1 (en) * 1999-11-29 2002-12-24 Distek, Inc. Intrinsic dissolution apparatus with stationary sample holder
FR2828810B1 (fr) * 2001-08-27 2005-10-07 Lvmh Rech Composition cosmetique a effet tenseur contenant un polymere d'origine naturelle et un agent hydratant polyhydroxyle
KR100574554B1 (ko) * 2004-05-28 2006-04-27 한미약품 주식회사 니아신의 경구투여용 서방성 조성물
AU2006228869A1 (en) * 2005-03-30 2006-10-05 Astion Pharma A/S Oxaprozin or a closely related compound for the treatment of eczema
PE20061303A1 (es) * 2005-03-30 2006-12-07 Astion Dev As Composicion farmaceutica que comprende oxaprozina
WO2006130726A2 (en) * 2005-06-01 2006-12-07 Teva Pharmaceutical Industries, Ltd. Use of ladostigil for the treatment of multiple sclerosis
CA2677193C (en) 2007-02-01 2015-06-30 Takeda Pharmaceutical Company Limited Tablet preparation without causing a tableting trouble
KR20230158644A (ko) 2011-02-10 2023-11-20 엑셀리시스, 인코포레이티드 퀴놀린 화합물들의 제조 방법들 및 상기 화합물들을 함유하는 약학 조성물들
SG11201405353VA (en) * 2012-03-22 2014-09-26 Transtech Pharma Llc Tris(hydroxymethyl)aminomethane salts of a small-molecule glp1r agonist and pharmaceutical compositions and uses thereof
EP3275433A1 (de) * 2016-07-29 2018-01-31 Som Innovation Biotech S.L. Zusammensetzung mit verzögerter freisetzung mit mikronisiertem tolcapon

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1206403A (en) * 1966-12-15 1970-09-23 Wyeth John & Brother Ltd Oxazoles
US3578671A (en) * 1967-11-06 1971-05-11 Wyeth John & Brother Ltd Oxazoles
US3998815A (en) * 1974-06-24 1976-12-21 Interx Research Corporation 1-hydrocarbonoyloxymethyl-3-carbamoyl or 3-carboethoxy-pyridinium salts
US4190584A (en) * 1976-08-13 1980-02-26 John Wyeth & Brother Limited Process for preparing oxazoles
GB2097389B (en) * 1981-04-28 1984-11-28 Wyeth John & Brother Ltd Oxazole derivative
IE52909B1 (en) * 1981-04-28 1988-04-13 Wyeth John & Brother Ltd Oxazole derivatives
US4385049A (en) * 1981-05-12 1983-05-24 K-V Pharmaceutical Company Stable high internal phase ratio topical emulsions
US4599359A (en) * 1982-12-09 1986-07-08 Stephen A. Cooper Hydroxyzine-containing analgesic combinations
GB8329326D0 (en) * 1983-11-03 1983-12-07 Wyeth John & Brother Ltd Oxazole derivatives
IT1204751B (it) * 1986-01-03 1989-03-10 Therapicon Srl Derivati idrosolubili dell'acido 4,5 -difenil- 2 -ossazolpropionico,loro preparazione ed utilizzo in composizioni farmaceutiche
GB8630273D0 (en) * 1986-12-18 1987-01-28 Til Medical Ltd Pharmaceutical delivery systems
US5059626A (en) * 1988-07-25 1991-10-22 Applied Analytical Industries, Inc. Liquid oral pharmaceutical compositions of non-steroidal anti-inflammatory drugs
US5350769A (en) * 1990-10-30 1994-09-27 Ss Pharmaceutical Co., Ltd. Antiinflammatory gel preparation
WO1995007103A1 (en) * 1993-09-07 1995-03-16 The Procter & Gamble Company Compositions containing an amino acid salt of propionic acid non-steroidal anti-inflammatory agent and at least one of a decongestant, an expectorant, an antihistamine and an antitussive
EP0717624A1 (de) * 1993-09-07 1996-06-26 The Procter & Gamble Company Zusammensetzungen, welche aminosäure salzen von propionsäure nichtsteroiden antiinflammatorischen arzneimitteln und kaffein enthalten

Also Published As

Publication number Publication date
WO1997044022A1 (en) 1997-11-27
NO985414D0 (no) 1998-11-20
ES2248850T3 (es) 2006-03-16
TW586929B (en) 2004-05-11
CN1225580A (zh) 1999-08-11
RU2197244C2 (ru) 2003-01-27
CA2255064C (en) 2006-10-10
US6030643A (en) 2000-02-29
PL330145A1 (en) 1999-04-26
IL126998A (en) 2003-12-10
CZ370298A3 (cs) 1999-05-12
EP0901372A1 (de) 1999-03-17
EP0901372B1 (de) 2005-07-20
IL126998A0 (en) 1999-09-22
CA2255064A1 (en) 1997-11-27
AU3059797A (en) 1997-12-09
KR20000015865A (ko) 2000-03-15
NZ332861A (en) 2000-08-25
NO985414L (no) 1999-01-19
BR9710448A (pt) 1999-08-17
AU718030B2 (en) 2000-04-06
JP2001503734A (ja) 2001-03-21
DE69733752D1 (de) 2005-08-25
CN1129429C (zh) 2003-12-03
JP4185974B2 (ja) 2008-11-26
DE69733752T2 (de) 2006-06-01
ZA974366B (en) 1998-05-20

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties