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ATE298764T1 - Sektretierter e1/e2 hepatitis c virus-komplex erhalten aus c-terminal verkürzten polypeptiden e1 und e2 - Google Patents

Sektretierter e1/e2 hepatitis c virus-komplex erhalten aus c-terminal verkürzten polypeptiden e1 und e2

Info

Publication number
ATE298764T1
ATE298764T1 AT95928779T AT95928779T ATE298764T1 AT E298764 T1 ATE298764 T1 AT E298764T1 AT 95928779 T AT95928779 T AT 95928779T AT 95928779 T AT95928779 T AT 95928779T AT E298764 T1 ATE298764 T1 AT E298764T1
Authority
AT
Austria
Prior art keywords
polypeptides
hepatitis
secreted
complex obtained
virus complex
Prior art date
Application number
AT95928779T
Other languages
English (en)
Inventor
Mark Selby
Michael Houghton
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Priority claimed from PCT/US1995/010035 external-priority patent/WO1996004301A2/en
Application granted granted Critical
Publication of ATE298764T1 publication Critical patent/ATE298764T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/24011Flaviviridae
    • C12N2770/24211Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/826Viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT95928779T 1994-07-29 1995-07-26 Sektretierter e1/e2 hepatitis c virus-komplex erhalten aus c-terminal verkürzten polypeptiden e1 und e2 ATE298764T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28295994A 1994-07-29 1994-07-29
US50660895A 1995-07-25 1995-07-25
PCT/US1995/010035 WO1996004301A2 (en) 1994-07-29 1995-07-26 Novel hepatitis c e1 and e2 truncated polypeptides and methods of obtaining the same

Publications (1)

Publication Number Publication Date
ATE298764T1 true ATE298764T1 (de) 2005-07-15

Family

ID=26961777

Family Applications (2)

Application Number Title Priority Date Filing Date
AT04077562T ATE417109T1 (de) 1994-07-29 1995-07-26 Hepatitis c e2 verkuerzte polypeptid sowie verfahen zu seiner herstellung
AT95928779T ATE298764T1 (de) 1994-07-29 1995-07-26 Sektretierter e1/e2 hepatitis c virus-komplex erhalten aus c-terminal verkürzten polypeptiden e1 und e2

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT04077562T ATE417109T1 (de) 1994-07-29 1995-07-26 Hepatitis c e2 verkuerzte polypeptid sowie verfahen zu seiner herstellung

Country Status (12)

Country Link
US (1) US6326171B1 (de)
EP (2) EP0773957B1 (de)
JP (4) JP3793571B2 (de)
AT (2) ATE417109T1 (de)
CA (1) CA2195312A1 (de)
DE (2) DE69535899D1 (de)
DK (2) DK0773957T3 (de)
ES (2) ES2244965T3 (de)
IL (3) IL114775A (de)
MX (1) MX9700677A (de)
MY (1) MY121563A (de)
PT (1) PT1510580E (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4458556B2 (ja) * 1997-05-06 2010-04-28 ノバルティス バクシンズ アンド ダイアグノスティックス,インコーポレーテッド C型肝炎のe2短縮型ポリペプチドの細胞内生成
WO2001047551A2 (en) * 1999-12-01 2001-07-05 Chiron Corporation Eliciting antibodies specific for hepatitis c virus (hcv)
US7439042B2 (en) * 2002-12-16 2008-10-21 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis C infection
CN102614510A (zh) * 2004-10-18 2012-08-01 全球免疫股份有限公司 基于酵母的对慢性丙型肝炎感染的治疗
WO2009131681A2 (en) * 2008-04-22 2009-10-29 Rutgers, The State University Hcv e2 construct compositions and methods
US9758794B2 (en) 2008-04-22 2017-09-12 Rutgers, The State University Of New Jersey HCV E2 construct compositions and methods
WO2010033841A1 (en) 2008-09-19 2010-03-25 Globeimmune, Inc. Immunotherapy for chronic hepatitis c virus infection
FR2984328B1 (fr) 2011-12-20 2016-12-30 Bio-Rad Innovations Procede de detection d'une infection par le virus de l'hepatite c
CN105621806B (zh) * 2016-01-22 2018-10-30 南京贝克特环保科技有限公司 一种快速处理餐厨垃圾废水的生物聚沉氧化工艺

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1049686C (zh) 1987-11-18 2000-02-23 希龙股份有限公司 非a和非b肝炎病毒的诊断及疫苗
UA50829C2 (uk) 1989-03-17 2002-11-15 Чірон Корпорейшн Очищений поліпептид, що містить антиген вірусу гепатиту с, полінуклеотид, вектор, клітини, система експресії, моноклональне антитіло, препарат поліклональних антитіл, нуклеотидна проба, аналітичні набори, спосіб виявлення нуклеїнових кислот, способи імуноаналізу, вакцина, спосіб одержання антитіл
EP0398748B1 (de) 1989-05-18 2002-01-09 Chiron Corporation NANBV-Diagnostika: Polynukleotide, geeignet für Reihenuntersuchungen auf Hepatitis C-Virus
WO1992002628A1 (en) 1990-08-02 1992-02-20 Chiron Corporation Expression of human cmv glycoprotein-h using the baculovirus-insect cell expression system
US6274148B1 (en) * 1990-11-08 2001-08-14 Chiron Corporation Hepatitis C virus asialoglycoproteins
RO115446B1 (ro) 1990-11-08 2000-02-28 Chiron Corp Procedeu de obtinere a asialoglicoproteinelor purificate provenind de la virusul hepatitei c
DK0721505T4 (da) 1994-07-29 2006-08-14 Innogenetics Nv Rensede hepatitis C-virus-kappeproteiner til diagnostisk og terapeutisk anvendelse

Also Published As

Publication number Publication date
EP1510580B1 (de) 2008-12-10
JP3793571B2 (ja) 2006-07-05
DK0773957T3 (da) 2005-10-24
DE69535899D1 (de) 2009-01-22
US6326171B1 (en) 2001-12-04
EP0773957A2 (de) 1997-05-21
ES2244965T3 (es) 2005-12-16
MX9700677A (es) 1997-04-30
JP2007006901A (ja) 2007-01-18
ES2316920T3 (es) 2009-04-16
JP2007291126A (ja) 2007-11-08
ATE417109T1 (de) 2008-12-15
EP1510580A3 (de) 2005-06-22
PT1510580E (pt) 2009-02-18
DE69534296D1 (de) 2005-08-18
JP2005290010A (ja) 2005-10-20
JP4298735B2 (ja) 2009-07-22
JP2002515005A (ja) 2002-05-21
IL185119A0 (en) 2007-12-03
DK1510580T3 (da) 2009-02-16
CA2195312A1 (en) 1996-02-15
EP0773957B1 (de) 2005-06-29
MY121563A (en) 2006-02-28
EP1510580A2 (de) 2005-03-02
DE69534296T2 (de) 2006-04-27
IL114775A (en) 2006-12-10
IL137840A0 (en) 2001-10-31

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