ATE271603T1 - Identifizierungsverfahren für substanzen die an das pyk2 polypeptid binden - Google Patents
Identifizierungsverfahren für substanzen die an das pyk2 polypeptid bindenInfo
- Publication number
- ATE271603T1 ATE271603T1 AT97952333T AT97952333T ATE271603T1 AT E271603 T1 ATE271603 T1 AT E271603T1 AT 97952333 T AT97952333 T AT 97952333T AT 97952333 T AT97952333 T AT 97952333T AT E271603 T1 ATE271603 T1 AT E271603T1
- Authority
- AT
- Austria
- Prior art keywords
- bind
- substances
- identification method
- features
- pyk2 polypeptide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Bakery Products And Manufacturing Methods Therefor (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Tires In General (AREA)
- Detergent Compositions (AREA)
- Confectionery (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3282496P | 1996-12-11 | 1996-12-11 | |
PCT/US1997/022565 WO1998026054A2 (en) | 1996-12-11 | 1997-12-09 | Pyk2 related products and methods |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE271603T1 true ATE271603T1 (de) | 2004-08-15 |
Family
ID=21867009
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97952333T ATE271603T1 (de) | 1996-12-11 | 1997-12-09 | Identifizierungsverfahren für substanzen die an das pyk2 polypeptid binden |
Country Status (11)
Country | Link |
---|---|
US (2) | US20020048782A1 (de) |
EP (1) | EP0948604B1 (de) |
JP (1) | JP2001505779A (de) |
AT (1) | ATE271603T1 (de) |
AU (1) | AU5596998A (de) |
CA (1) | CA2274805A1 (de) |
DE (1) | DE69729954T2 (de) |
DK (1) | DK0948604T3 (de) |
ES (1) | ES2227729T3 (de) |
PT (1) | PT948604E (de) |
WO (1) | WO1998026054A2 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6861442B1 (en) | 1998-12-30 | 2005-03-01 | Sugen, Inc. | PYK2 and inflammation |
EP1141722A1 (de) * | 1998-12-31 | 2001-10-10 | Sugen, Inc. | Pyk2 (raftk) und entzündung |
DE19860833C1 (de) * | 1998-12-30 | 2000-09-07 | Albrecht E Sippel | Methode zur zellulären High-Throughput(Hochdurchsatz)-Detektion von Rezeptor-Liganden-Interaktionen |
EP1630559A3 (de) * | 1998-12-30 | 2006-06-07 | Sugen, Inc. | PYK2 (RAFTK) und Entzündung |
WO2000049144A2 (en) * | 1999-02-22 | 2000-08-24 | Sugen, Inc. | Pyk2 binding proteins |
DE10037759A1 (de) * | 2000-08-03 | 2002-07-04 | Gruenenthal Gmbh | Screeningverfahren |
EP1228766A1 (de) * | 2001-01-31 | 2002-08-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | PYK2 Phosphorylierung durch HER3 induziert Tumorinvasion |
DE10123055A1 (de) * | 2001-05-11 | 2003-03-20 | Gruenenthal Gmbh | Screeningverfahren mit PIM1-Kinase oder PIM3-Kinase |
DE10128541A1 (de) * | 2001-06-13 | 2003-02-20 | Gruenenthal Gmbh | Screening-Verfahren mit BNPI und DNPI |
JP2005514013A (ja) * | 2001-12-19 | 2005-05-19 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | 1465、1587、2146、2207、32838、336、および52908を使用して疼痛および有痛性障害を処置する際の方法および組成物 |
US20040171062A1 (en) * | 2002-02-28 | 2004-09-02 | Plexxikon, Inc. | Methods for the design of molecular scaffolds and ligands |
CA2497434A1 (en) * | 2002-09-19 | 2004-04-01 | Pfizer Products Inc. | Inducible focal adhesion kinase cell assay |
US20050170431A1 (en) * | 2003-02-28 | 2005-08-04 | Plexxikon, Inc. | PYK2 crystal structure and uses |
WO2005002573A2 (en) * | 2003-06-06 | 2005-01-13 | Elan Pharmaceuticals, Inc. | Methods for using modulators of proline-rich tyrosine kinase 2 |
US20050148029A1 (en) * | 2003-09-29 | 2005-07-07 | Biosite, Inc. | Methods and compositions for determining treatment regimens in systemic inflammatory response syndromes |
AR056857A1 (es) | 2005-12-30 | 2007-10-24 | U3 Pharma Ag | Anticuerpos dirigidos hacia her-3 (receptor del factor de crecimiento epidérmico humano-3) y sus usos |
WO2009155060A2 (en) * | 2008-05-28 | 2009-12-23 | Mayo Foundation For Medical Education And Research | Anti-pyk2 antibodies |
CN102812045B (zh) | 2009-11-13 | 2018-04-13 | 第一三共欧洲有限公司 | 用于治疗或预防人表皮生长因子受体‑3(her‑3)相关疾病的材料和方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4343940A (en) * | 1979-02-13 | 1982-08-10 | Mead Johnson & Company | Anti-tumor quinazoline compounds |
DE3069468D1 (en) * | 1979-12-19 | 1984-11-22 | Nat Res Dev | Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents |
DE3611194A1 (de) * | 1986-04-04 | 1987-10-08 | Bayer Ag | Cancerostatisches mittel |
DE3920029C2 (de) * | 1988-06-30 | 1999-05-20 | Clariant Finance Bvi Ltd | Farbstoffe zum Färben von Kunststoffen |
US5837815A (en) * | 1994-12-15 | 1998-11-17 | Sugen, Inc. | PYK2 related polypeptide products |
US5880141A (en) * | 1995-06-07 | 1999-03-09 | Sugen, Inc. | Benzylidene-Z-indoline compounds for the treatment of disease |
-
1997
- 1997-12-09 AT AT97952333T patent/ATE271603T1/de not_active IP Right Cessation
- 1997-12-09 AU AU55969/98A patent/AU5596998A/en not_active Abandoned
- 1997-12-09 DK DK97952333T patent/DK0948604T3/da active
- 1997-12-09 PT PT97952333T patent/PT948604E/pt unknown
- 1997-12-09 JP JP52689998A patent/JP2001505779A/ja not_active Withdrawn
- 1997-12-09 EP EP97952333A patent/EP0948604B1/de not_active Expired - Lifetime
- 1997-12-09 CA CA002274805A patent/CA2274805A1/en not_active Abandoned
- 1997-12-09 US US08/987,689 patent/US20020048782A1/en not_active Abandoned
- 1997-12-09 ES ES97952333T patent/ES2227729T3/es not_active Expired - Lifetime
- 1997-12-09 WO PCT/US1997/022565 patent/WO1998026054A2/en active IP Right Grant
- 1997-12-09 DE DE69729954T patent/DE69729954T2/de not_active Expired - Fee Related
-
2002
- 2002-11-13 US US10/292,524 patent/US20030119067A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1998026054A2 (en) | 1998-06-18 |
US20020048782A1 (en) | 2002-04-25 |
DK0948604T3 (da) | 2004-11-22 |
WO1998026054A3 (en) | 1998-09-03 |
DE69729954T2 (de) | 2005-09-08 |
EP0948604B1 (de) | 2004-07-21 |
PT948604E (pt) | 2004-10-29 |
AU5596998A (en) | 1998-07-03 |
ES2227729T3 (es) | 2005-04-01 |
EP0948604A2 (de) | 1999-10-13 |
DE69729954D1 (de) | 2004-08-26 |
JP2001505779A (ja) | 2001-05-08 |
US20030119067A1 (en) | 2003-06-26 |
CA2274805A1 (en) | 1998-06-18 |
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Legal Events
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UEP | Publication of translation of european patent specification |
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REN | Ceased due to non-payment of the annual fee |