ATE266663T1 - Acrylamid-derivate und verfahren zu deren herstellung - Google Patents

Acrylamid-derivate und verfahren zu deren herstellung

Info

Publication number: ATE266663T1
Authority: AT; Austria
Prior art keywords: acrylamide derivatives; general formula; production; derivatives represented; eüindole
Prior art date: 1994-11-29

Application number

AT95937194T

Other languages

English (en)

Inventor

Yasumichi Fukuda

Shigeki Seto

Yasuo Oomori

Hiroyuki Ebisu

Shiro Terashima

Original Assignee

Kyorin Seiyaku Kk

Sagami Chem Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-29

Filing date

1995-11-28

Publication date

2004-05-15

1995-11-28 Application filed by Kyorin Seiyaku Kk, Sagami Chem Res filed Critical Kyorin Seiyaku Kk

2004-05-15 Application granted granted Critical

2004-05-15 Publication of ATE266663T1 publication Critical patent/ATE266663T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Indole Compounds (AREA)
Fertilizers (AREA)

AT95937194T 1994-11-29 1995-11-28 Acrylamid-derivate und verfahren zu deren herstellung ATE266663T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP29527494		1994-11-29
PCT/JP1995/002413 WO1996016965A1 (fr)	1994-11-29	1995-11-28	Derives d'acrylamide et leur procede de production

Publications (1)

Publication Number	Publication Date
ATE266663T1 true ATE266663T1 (de)	2004-05-15

Family

ID=17818480

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95937194T ATE266663T1 (de)	1994-11-29	1995-11-28	Acrylamid-derivate und verfahren zu deren herstellung

Country Status (12)

Country	Link
US (1)	US5786486A (de)
EP (1)	EP0799827B1 (de)
KR (1)	KR100395083B1 (de)
CN (1)	CN1051552C (de)
AT (1)	ATE266663T1 (de)
AU (1)	AU693283B2 (de)
CA (1)	CA2205872A1 (de)
DE (1)	DE69533043T2 (de)
FI (1)	FI972074A0 (de)
HU (1)	HUT77654A (de)
MX (1)	MX9703917A (de)
WO (1)	WO1996016965A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ506101A (en)	1998-01-28	2003-06-30	Shionogi & Co	Tricyclic immunosupressant, anti-allergic and IgE production suppressant compounds
EP1434778A4 (de)	2001-05-31	2005-07-13	Medarex Inc	Cytotoxine und prodrugs, linker und stabilisatoren dafür
AU2005244980B2 (en) *	2004-05-19	2011-09-15	E. R. Squibb & Sons, L.L.C.	Chemical linkers and conjugates thereof
RU2402548C2 (ru) *	2004-05-19	2010-10-27	Медарекс, Инк.	Химические линкеры и их конъюгаты
CA2598522A1 (en) *	2005-02-18	2006-08-24	Medarex, Inc.	Human monoclonal antibodies to prostate specific membrane antigen (psma)
US7714016B2 (en) *	2005-04-08	2010-05-11	Medarex, Inc.	Cytotoxic compounds and conjugates with cleavable substrates
WO2007051081A1 (en)	2005-10-26	2007-05-03	Medarex, Inc.	Methods and compounds for preparing cc-1065 analogs
CA2627190A1 (en)	2005-11-10	2007-05-24	Medarex, Inc.	Duocarmycin derivatives as novel cytotoxic compounds and conjugates
TWI412367B (zh)	2006-12-28	2013-10-21	Medarex Llc	化學鏈接劑與可裂解基質以及其之綴合物
WO2008103693A2 (en)	2007-02-21	2008-08-28	Medarex, Inc.	Chemical linkers with single amino acids and conjugates thereof
WO2014080251A1 (en)	2012-11-24	2014-05-30	Hangzhou Dac Biotech Co., Ltd.	Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
WO2015127685A1 (en)	2014-02-28	2015-09-03	Hangzhou Dac Biotech Co., Ltd	Charged linkers and their uses for conjugation
AU2015242213A1 (en)	2015-07-12	2018-03-08	Hangzhou Dac Biotech Co., Ltd	Bridge linkers for conjugation of cell-binding molecules
US9839687B2 (en)	2015-07-15	2017-12-12	Suzhou M-Conj Biotech Co., Ltd.	Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
CN110099682B (zh)	2016-11-14	2023-03-31	杭州多禧生物科技有限公司	偶联连接体，含有此连接体的细胞结合分子-药物偶联物及其制备和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1238907A (en) *	1984-02-21	1988-07-05	Robert C. Kelly	1,2,8,8a-tetrahydrocyclopropa¬c\|pyrrolo(3,2-e)- indol-4(5h)-ones and related compounds
MX9203200A (es) *	1986-12-19	1992-09-01	Upjohn Co	Analogos de cc. 1065 novedosos.
EP0520435A3 (en) *	1991-06-28	1993-05-05	Kyowa Hakko Kogyo Co., Ltd.	Dc-89 derivatives
JP2502005B2 (ja)	1992-04-27	1996-05-29	オンキヨー株式会社	バイオフィ―ドバックシステム
JP3514490B2 (ja) *	1992-08-21	2004-03-31	杏林製薬株式会社	トリフルオロメチルピロロインドールカルボン酸エステル誘導体及びその製造方法

1995
- 1995-11-28 CN CN95197472A patent/CN1051552C/zh not_active Expired - Fee Related
- 1995-11-28 AT AT95937194T patent/ATE266663T1/de not_active IP Right Cessation
- 1995-11-28 WO PCT/JP1995/002413 patent/WO1996016965A1/ja active IP Right Grant
- 1995-11-28 EP EP95937194A patent/EP0799827B1/de not_active Expired - Lifetime
- 1995-11-28 AU AU39370/95A patent/AU693283B2/en not_active Ceased
- 1995-11-28 US US08/849,160 patent/US5786486A/en not_active Expired - Fee Related
- 1995-11-28 DE DE69533043T patent/DE69533043T2/de not_active Expired - Fee Related
- 1995-11-28 HU HU9800067A patent/HUT77654A/hu not_active Application Discontinuation
- 1995-11-28 MX MX9703917A patent/MX9703917A/es not_active IP Right Cessation
- 1995-11-28 KR KR1019970703468A patent/KR100395083B1/ko not_active IP Right Cessation
- 1995-11-28 CA CA002205872A patent/CA2205872A1/en not_active Abandoned
1997
- 1997-05-14 FI FI972074A patent/FI972074A0/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
DE69533043T2 (de)	2005-04-07
CA2205872A1 (en)	1996-06-06
DE69533043D1 (de)	2004-06-17
HUT77654A (hu)	1998-07-28
AU3937095A (en)	1996-06-19
EP0799827B1 (de)	2004-05-12
FI972074A0 (fi)	1997-05-14
CN1051552C (zh)	2000-04-19
WO1996016965A1 (fr)	1996-06-06
US5786486A (en)	1998-07-28
KR100395083B1 (ko)	2004-02-05
EP0799827A1 (de)	1997-10-08
MX9703917A (es)	1998-05-31
CN1174553A (zh)	1998-02-25
EP0799827A4 (de)	1998-01-28
AU693283B2 (en)	1998-06-25

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Legal Events

Date	Code	Title	Description
2004-11-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties