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ATE266426T1 - Mikroverkapselte fluorierte gase zur anwendung als bilderzeugende mittel - Google Patents

Mikroverkapselte fluorierte gase zur anwendung als bilderzeugende mittel

Info

Publication number
ATE266426T1
ATE266426T1 AT97906791T AT97906791T ATE266426T1 AT E266426 T1 ATE266426 T1 AT E266426T1 AT 97906791 T AT97906791 T AT 97906791T AT 97906791 T AT97906791 T AT 97906791T AT E266426 T1 ATE266426 T1 AT E266426T1
Authority
AT
Austria
Prior art keywords
microparticle
incorporating
encapsuled
micro
imaging agent
Prior art date
Application number
AT97906791T
Other languages
English (en)
Inventor
Howard Bernstein
Julie Ann Straub
Edith Mathiowitz
Henry T Brush
Richard E Wing
Original Assignee
Acusphere Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27086474&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE266426(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/611,248 external-priority patent/US5611344A/en
Application filed by Acusphere Inc filed Critical Acusphere Inc
Application granted granted Critical
Publication of ATE266426T1 publication Critical patent/ATE266426T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48Diagnostic techniques
    • A61B8/481Diagnostic techniques involving the use of contrast agent, e.g. microbubbles introduced into the bloodstream
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/22Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223Microbubbles, hollow microspheres, free gas bubbles, gas microspheres

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Acoustics & Sound (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
AT97906791T 1996-03-05 1997-02-27 Mikroverkapselte fluorierte gase zur anwendung als bilderzeugende mittel ATE266426T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/611,248 US5611344A (en) 1996-03-05 1996-03-05 Microencapsulated fluorinated gases for use as imaging agents
US08/745,676 US5853698A (en) 1996-03-05 1996-11-08 Method for making porous microparticles by spray drying
PCT/US1997/003117 WO1997032609A2 (en) 1996-03-05 1997-02-27 Microencapsulated fluorinated gases for use as imaging agents

Publications (1)

Publication Number Publication Date
ATE266426T1 true ATE266426T1 (de) 2004-05-15

Family

ID=27086474

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97906791T ATE266426T1 (de) 1996-03-05 1997-02-27 Mikroverkapselte fluorierte gase zur anwendung als bilderzeugende mittel

Country Status (21)

Country Link
US (1) US6132699A (de)
EP (1) EP0904113B1 (de)
JP (1) JP3178724B2 (de)
AT (1) ATE266426T1 (de)
AU (1) AU721209B2 (de)
BR (1) BR9707936B1 (de)
CA (1) CA2247151C (de)
CZ (1) CZ281298A3 (de)
DE (1) DE69729088T2 (de)
DK (1) DK0904113T3 (de)
ES (1) ES2221687T3 (de)
HK (1) HK1020428A1 (de)
HU (1) HU226714B1 (de)
ID (1) ID17753A (de)
IL (1) IL126073A (de)
MY (1) MY124549A (de)
NO (1) NO312940B1 (de)
NZ (1) NZ331460A (de)
PT (1) PT904113E (de)
TW (1) TWI246426B (de)
WO (1) WO1997032609A2 (de)

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US5837221A (en) * 1996-07-29 1998-11-17 Acusphere, Inc. Polymer-lipid microencapsulated gases for use as imaging agents
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
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US6223455B1 (en) 1999-05-03 2001-05-01 Acusphere, Inc. Spray drying apparatus and methods of use
ES2249316T3 (es) * 1999-12-10 2006-04-01 Iscience Corporation Tratamiento de patologias oculares.
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US6793626B2 (en) 2001-01-17 2004-09-21 Fuji Photo Film Co., Ltd. Ultrasonic scatterer, ultrasonic imaging method and ultrasonic imaging apparatus
DE10119522A1 (de) * 2001-04-20 2002-12-05 Innovacell Biotechnologie Gmbh Herstellung und Anwendung einer Suspensionszusammensetzung mit einem Ultraschall-Kontrastmittel
EP1458360B1 (de) 2001-12-19 2011-05-11 Novartis AG Pulmonale verabreichung von aminoglykosiden
US6919068B2 (en) * 2002-05-17 2005-07-19 Point Biomedical Corporation Method of preparing gas-filled polymer matrix microparticles useful for echographic imaging
US20040121003A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
US6962006B2 (en) * 2002-12-19 2005-11-08 Acusphere, Inc. Methods and apparatus for making particles using spray dryer and in-line jet mill
US20050171425A1 (en) * 2004-01-16 2005-08-04 Phantoms-By-Design Medical devices having MRI-enhancing encapsulated fluids
JP4808214B2 (ja) * 2004-06-04 2011-11-02 アキュスフィア, インコーポレイテッド 超音波造影剤の投薬処方物
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
CA2631493A1 (en) * 2005-12-15 2007-06-21 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration
US20070148211A1 (en) * 2005-12-15 2007-06-28 Acusphere, Inc. Processes for making particle-based pharmaceutical formulations for oral administration
DE102008045152A1 (de) * 2008-07-09 2010-01-14 Universität Duisburg-Essen Künstliche Sauerstoffträger und ihre Verwendung
KR101061224B1 (ko) * 2008-10-08 2011-08-31 포항공과대학교 산학협력단 X 선을 이용한 유동정보 측정용 캡슐
NL2003660C2 (en) * 2009-10-16 2011-04-19 Giskit B V Composition and method for medical imaging of body cavities.
JP2011140527A (ja) * 2011-04-20 2011-07-21 Acusphere Inc 超音波造影剤の投薬処方物

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Also Published As

Publication number Publication date
NO984089L (no) 1998-09-04
WO1997032609A2 (en) 1997-09-12
ES2221687T3 (es) 2005-01-01
JP2000501745A (ja) 2000-02-15
HK1020428A1 (en) 2000-04-20
CA2247151A1 (en) 1997-09-12
MY124549A (en) 2006-06-30
NO312940B1 (no) 2002-07-22
IL126073A (en) 2002-02-10
NZ331460A (en) 1998-12-23
DE69729088D1 (de) 2004-06-17
HUP9902897A3 (en) 2000-03-28
WO1997032609A3 (en) 1998-01-29
BR9707936B1 (pt) 2010-12-14
CA2247151C (en) 2008-05-20
NO984089D0 (no) 1998-09-04
PT904113E (pt) 2004-09-30
BR9707936A (pt) 2000-01-04
TWI246426B (en) 2006-01-01
HUP9902897A2 (hu) 2000-01-28
ID17753A (id) 1998-01-22
JP3178724B2 (ja) 2001-06-25
DE69729088T2 (de) 2005-05-12
DK0904113T3 (da) 2004-08-30
US6132699A (en) 2000-10-17
AU2139297A (en) 1997-09-22
EP0904113A2 (de) 1999-03-31
AU721209B2 (en) 2000-06-29
IL126073A0 (en) 1999-05-09
CZ281298A3 (cs) 1999-01-13
HU226714B1 (en) 2009-07-28
EP0904113B1 (de) 2004-05-12

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