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ATE253635T1 - Rekombinante spinnerseide analoge - Google Patents

Rekombinante spinnerseide analoge

Info

Publication number
ATE253635T1
ATE253635T1 AT94920732T AT94920732T ATE253635T1 AT E253635 T1 ATE253635 T1 AT E253635T1 AT 94920732 T AT94920732 T AT 94920732T AT 94920732 T AT94920732 T AT 94920732T AT E253635 T1 ATE253635 T1 AT E253635T1
Authority
AT
Austria
Prior art keywords
spinner
analogue
silk
recombinant
coli
Prior art date
Application number
AT94920732T
Other languages
English (en)
Inventor
Stephen R Fahnestock
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Application granted granted Critical
Publication of ATE253635T1 publication Critical patent/ATE253635T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43518Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from spiders
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F02COMBUSTION ENGINES; HOT-GAS OR COMBUSTION-PRODUCT ENGINE PLANTS
    • F02BINTERNAL-COMBUSTION PISTON ENGINES; COMBUSTION ENGINES IN GENERAL
    • F02B75/00Other engines
    • F02B75/02Engines characterised by their cycles, e.g. six-stroke
    • F02B2075/022Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle
    • F02B2075/027Engines characterised by their cycles, e.g. six-stroke having less than six strokes per cycle four

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Materials For Medical Uses (AREA)
AT94920732T 1993-06-15 1994-06-15 Rekombinante spinnerseide analoge ATE253635T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7760093A 1993-06-15 1993-06-15
PCT/US1994/006689 WO1994029450A2 (en) 1993-06-15 1994-06-15 Novel, recombinantly produced spider silk analogs

Publications (1)

Publication Number Publication Date
ATE253635T1 true ATE253635T1 (de) 2003-11-15

Family

ID=22139030

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94920732T ATE253635T1 (de) 1993-06-15 1994-06-15 Rekombinante spinnerseide analoge

Country Status (7)

Country Link
US (1) US6268169B1 (de)
EP (2) EP1413585A3 (de)
JP (1) JPH08511426A (de)
AT (1) ATE253635T1 (de)
CA (1) CA2164692C (de)
DE (1) DE69433299T2 (de)
WO (1) WO1994029450A2 (de)

Families Citing this family (48)

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AU752704B2 (en) * 1997-10-24 2002-09-26 Invitrogen Corporation Recombinational cloning using nucleic acids having recombination sites
FR2774588B1 (fr) 1998-02-11 2000-05-05 Oreal Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue
US20010053931A1 (en) * 1999-11-24 2001-12-20 Salvatore J. Abbruzzese Thin-layered, endovascular silk-covered stent device and method of manufacture thereof
US6608242B1 (en) * 2000-05-25 2003-08-19 E. I. Du Pont De Nemours And Company Production of silk-like proteins in plants
CA2411600A1 (en) * 2000-06-09 2001-12-13 Ipk Institut Fur Pflanzenzengenetik Und Kulturplanzenforschung Synthetic spider silk proteins and the expression thereof in transgenic plants
US7198924B2 (en) 2000-12-11 2007-04-03 Invitrogen Corporation Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
FR2817260A1 (fr) * 2000-11-29 2002-05-31 Centre Nat Rech Scient Peptides ayant des proprietes anti-inflammatoires, leurs utilisations et les compositions les contenant
CN1223602C (zh) * 2001-07-13 2005-10-19 一泰医药研究(深圳)有限公司 序列号11的生物活性肽
RU2305107C2 (ru) 2001-07-13 2007-08-27 СиЭмЭс ПЕПТАЙДЗ ПЭЙТЕНТ ХОЛДИНГ КОМПАНИ ЛИМИТЕД Пептид, стимулирующий противоопухолевый иммунный ответ, фармацевтическая композиция на его основе, способ лечения млекопитающего и способ модуляции иммунного ответа
US7057023B2 (en) * 2002-01-11 2006-06-06 Nexia Biotechnologies Inc. Methods and apparatus for spinning spider silk protein
US20060019348A1 (en) * 2002-05-23 2006-01-26 Tetsuo Asakura Method of mass producing silk protein and gene recombinant silk-like protein with added functionality
US20040117874A1 (en) * 2002-10-15 2004-06-17 Jianjun Yang Methods for accumulating translocated proteins
US20040132978A1 (en) * 2002-11-12 2004-07-08 Fahnestock Stephen R. Method for purifying and recovering silk proteins in soluble form and uses thereof
JP2004206910A (ja) * 2002-12-24 2004-07-22 Sumitomo Wiring Syst Ltd ヒューズコネクタ
EP2181704B1 (de) 2002-12-30 2015-05-06 Angiotech International Ag Wirkstofffreisetzung von schnell gelierender Polymerzusammensetzung
AU2003300022A1 (en) * 2002-12-30 2004-07-29 Angiotech International Ag Silk-containing stent graft
US7060260B2 (en) * 2003-02-20 2006-06-13 E.I. Du Pont De Nemours And Company Water-soluble silk proteins in compositions for skin care, hair care or hair coloring
GB0319174D0 (en) * 2003-08-15 2003-09-17 Spinox Ltd Apparatus and method for the selective assembly of protein
CA2536168A1 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Intravascular devices and fibrosis-inducing agents
EP2287341B1 (de) 2003-12-01 2013-02-13 Life Technologies Corporation Rekombinationsstellen enthaltende Nukleinsäuremoleküle und Verfahren zur Verwendung davon
US20080287651A1 (en) * 2004-01-13 2008-11-20 Toray Industries, Inc. Silk Thread Containing Spider Thread Protein and Silk Worm Producing the Silk Thread
US20050161058A1 (en) 2004-01-26 2005-07-28 Israel Yerushalmy Spider silk dental floss
TWI353252B (en) 2004-04-28 2011-12-01 Cms Peptides Patent Holding Company Ltd Biologically active peptide vapeehptllteaplnpk der
US20050261479A1 (en) * 2004-04-29 2005-11-24 Christian Hoffmann Method for purifying and recovering silk proteins using magnetic affinity separation
US20060027247A1 (en) * 2004-08-06 2006-02-09 Thomas Studney Transgenic spider silk floss
WO2006076711A2 (en) * 2005-01-14 2006-07-20 Trustees Of Tufts College Fibrous protein fusions and use thereof in the formation of advanced organic/inorganic composite materials
ZA200800457B (en) 2005-07-26 2009-08-26 Cms Peptides Patent Holding Co Novel biologically active peptides and their new uses
PL1757276T3 (pl) 2005-08-01 2008-02-29 Amsilk Gmbh Sposób otrzymywania nano-i mikrokapsułek z białka pajęczego jedwabiu
JP2009505668A (ja) * 2005-08-29 2009-02-12 テヒニシェ ウニヴェルズィテート ミュンヘン 修飾スパイダーシルクタンパク質
ES2403733T3 (es) 2005-10-05 2013-05-21 Commonwealth Scientific And Industrial Research Organisation Proteínas de seda
US8173772B2 (en) 2005-12-30 2012-05-08 Spiber Technologies Ab Spider silk proteins and methods for producing spider silk proteins
DE102007002222A1 (de) 2007-01-10 2008-07-17 Gustav Pirazzi & Comp. Kg Verwendung von künstlich hergestellter Spinnenseide
EP2121911A2 (de) * 2007-01-18 2009-11-25 Danisco US, INC., Genencor Division Modifizierte endoglucanase ii und verwendungsverfahren
BRPI0701826B1 (pt) 2007-03-16 2021-02-17 Embrapa - Empresa Brasileira De Pesquisa Agropecuária proteínas da teia de aranha nephilengys cruentata, avicularia juruensis e parawixia bistriata isoladas da biodiversidade brasileira
DE102007019622B4 (de) 2007-04-24 2010-07-01 Birgit Riesinger Expandierbarer Wundverband
ES2530190T3 (es) * 2007-06-20 2015-02-27 Basf Se Proteínas repetitivas sintéticas, su producción y su uso
WO2009097540A1 (en) 2008-02-01 2009-08-06 Entogenetics, Inc. Methods, compositions, and systems for production of recombinant spider silk polypeptides
KR20170054542A (ko) 2009-08-26 2017-05-17 커먼웰쓰 사이언티픽 앤드 인더스트리얼 리서치 오가니제이션 실크 도프의 제조 방법
JP5691052B2 (ja) 2010-09-10 2015-04-01 岡本株式会社 組換え生物及び組換え生物により作られるタンパク質
US9708376B2 (en) * 2012-05-02 2017-07-18 Spiber Technologies Ab Spider silk fusion protein structures without repetitive fragment for binding to an organic target
WO2014062134A1 (en) 2012-10-17 2014-04-24 Nanyang Technological University Compounds and methods for the production of suckerin and uses thereof
US20150293076A1 (en) * 2012-10-22 2015-10-15 Bolt Threads, Inc. Cellular Reprogramming for Product Optimization
EP3046585B1 (de) 2013-09-17 2021-08-25 Bolt Threads, Inc. Verfahren und zusammensetzungen zur synthetisierung verbesserter seidenfasern
WO2017115005A1 (en) 2015-12-29 2017-07-06 Teknologian Tutkimuskeskus Vtt Oy Production of fusion proteins in trichoderma
US11447532B2 (en) 2016-09-14 2022-09-20 Bolt Threads, Inc. Long uniform recombinant protein fibers
US11208736B2 (en) 2017-09-25 2021-12-28 Bolt Threads, Inc. Methods of generating highly-crystalline recombinant spider silk protein fibers
US11667682B2 (en) 2018-12-13 2023-06-06 Washington University Split intein mediated protein polymerization for microbial production of materials
WO2022269557A1 (en) * 2021-06-24 2022-12-29 Reliance Industries Limited Recombinant algae and production of spider silk protein from the recombinant algae

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0230702A1 (de) * 1986-01-22 1987-08-05 PA Consulting Services Limited Herstellung von Seide
JPS6236183A (ja) 1985-06-20 1987-02-17 ザ・サルク・インステイチユ−ト・バイオテクノロジ−/インダストリアル・アソシエイツ・インコ−ポレ−テツド サツカロミセス・セレビシエからのポリペプチドの発現および分泌
US5243038A (en) * 1986-11-04 1993-09-07 Protein Polymer Technologies, Inc. Construction of synthetic DNA and its use in large polypeptide synthesis
ATE233273T1 (de) * 1986-11-04 2003-03-15 Protein Polymer Tech Inc Herstellung synthetischer dns und deren verwendung bei der synthese grosser polypeptide
US5245012A (en) * 1990-04-19 1993-09-14 The United States Of America As Represented By The Secretary Of The Army Method to achieve solubilization of spider silk proteins
AU7691191A (en) * 1990-04-19 1991-11-11 United States Of America, As Represented By The Secretary Of The Army, The Recombinant spider silk proteins through genetic engineering
ATE189699T1 (de) * 1990-04-20 2000-02-15 Univ Wyoming Für spinnenseideprotein kodierende dns, dns enthaltender vektor, transformierte zelle und produkte davon
US5171505A (en) 1990-11-28 1992-12-15 E. I. Du Pont De Nemours And Company Process for spinning polypeptide fibers

Also Published As

Publication number Publication date
CA2164692A1 (en) 1994-12-22
EP1413585A3 (de) 2004-08-04
DE69433299T2 (de) 2004-09-09
DE69433299D1 (de) 2003-12-11
EP1413585A2 (de) 2004-04-28
WO1994029450A3 (en) 1995-02-09
WO1994029450A2 (en) 1994-12-22
EP0707645A1 (de) 1996-04-24
CA2164692C (en) 2003-02-04
US6268169B1 (en) 2001-07-31
JPH08511426A (ja) 1996-12-03
EP0707645B1 (de) 2003-11-05

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