ATE243198T1 - Verbindungen mit leicht spaltbaren bindungen zur inaktivierung von pathogenen - Google Patents
Verbindungen mit leicht spaltbaren bindungen zur inaktivierung von pathogenenInfo
- Publication number
- ATE243198T1 ATE243198T1 AT98901776T AT98901776T ATE243198T1 AT E243198 T1 ATE243198 T1 AT E243198T1 AT 98901776 T AT98901776 T AT 98901776T AT 98901776 T AT98901776 T AT 98901776T AT E243198 T1 ATE243198 T1 AT E243198T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- pathogens
- methods
- claveable
- inactivation
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 244000052769 pathogen Species 0.000 title abstract 3
- 230000002779 inactivation Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 230000000415 inactivating effect Effects 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 239000012620 biological material Substances 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 238000006731 degradation reaction Methods 0.000 abstract 1
- 210000003743 erythrocyte Anatomy 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
- B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
- B01J20/28033—Membrane, sheet, cloth, pad, lamellar or mat
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/08—Nitrogen atoms
- C07D219/10—Nitrogen atoms attached in position 9
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/64—Acridine or hydrogenated acridine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Heart & Thoracic Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- AIDS & HIV (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Analytical Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US77988597A | 1997-01-06 | 1997-01-06 | |
| US77983097A | 1997-01-07 | 1997-01-07 | |
| US4369697P | 1997-04-15 | 1997-04-15 | |
| PCT/US1998/000532 WO1998030545A1 (en) | 1997-01-06 | 1998-01-06 | Frangible compounds for pathogen inactivation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE243198T1 true ATE243198T1 (de) | 2003-07-15 |
Family
ID=27366374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98901776T ATE243198T1 (de) | 1997-01-06 | 1998-01-06 | Verbindungen mit leicht spaltbaren bindungen zur inaktivierung von pathogenen |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1021414B1 (de) |
| JP (2) | JP4551502B2 (de) |
| CN (2) | CN1248245B (de) |
| AT (1) | ATE243198T1 (de) |
| AU (1) | AU744089C (de) |
| CA (1) | CA2276532C (de) |
| DE (1) | DE69815703T2 (de) |
| ES (1) | ES2196530T3 (de) |
| HK (2) | HK1026702A1 (de) |
| WO (1) | WO1998030545A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2196530T3 (es) * | 1997-01-06 | 2003-12-16 | Cerus Corp | Compuestos de ruptura para inactivar patogenos. |
| ATE276771T1 (de) * | 1998-01-06 | 2004-10-15 | Cerus Corp | Verfahren zum quenchen von pathogen-inaktivatoren in biologischen materialien |
| JP2002517435A (ja) | 1998-06-11 | 2002-06-18 | シーラス コーポレイション | 動脈平滑筋細胞の増殖阻害のためのアルキル化化合物の使用 |
| US6403359B1 (en) | 1998-09-25 | 2002-06-11 | V. I. TECHNOLOGIES, Inc. | Solid phase quenching systems |
| US6150109A (en) | 1999-01-25 | 2000-11-21 | V. I. TECHNOLOGIES, Inc. | Lipophilic quenching of viral inactivating agents |
| US20020042043A1 (en) * | 2000-05-31 | 2002-04-11 | Adonis Stassinopoulos | Preparation of a pathogen inactivated solution of red blood cells having reduced immunogenicity |
| US9044523B2 (en) | 2000-06-15 | 2015-06-02 | Terumo Bct, Inc. | Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light |
| DE10051628B4 (de) * | 2000-10-18 | 2007-06-06 | Fresenius Hemocare Beteiligungs Gmbh | Einzelsträngiges Oligonukleotid und dessen Verwendung |
| CA2434256A1 (en) * | 2000-12-21 | 2003-07-31 | David Cook | Methods for inactivation of pathogens in biological materials |
| US7695725B2 (en) | 2003-02-06 | 2010-04-13 | Aduro Biotech | Modified free-living microbes, vaccine compositions and methods of use thereof |
| CA2515298C (en) * | 2003-02-06 | 2014-04-08 | Cerus Corporation | Modified free-living microbes, vaccine compositions and methods of use thereof |
| PT1592441E (pt) | 2003-02-06 | 2012-05-21 | Aduro Biotech | Listeria atenuada relativamente à entrada em células não patogénicas, vacinas compreendendo a listeria e métodos para sua utilização |
| US7842289B2 (en) | 2003-12-24 | 2010-11-30 | Aduro Biotech | Recombinant nucleic acid molecules, expression cassettes, and bacteria, and methods of use thereof |
| PT1838355E (pt) | 2004-10-29 | 2013-11-07 | Cerus Corp | Métodos de inibição melhorados destinados a um processo de inativação de glóbulos vermelhos |
| BRPI0911176B8 (pt) | 2008-04-09 | 2021-05-25 | Cerus Corp | método de tratar uma composição de célula vermelha sanguínea, composição de célula vermelha sanguínea, e método de reduzir a desidratação em uma composição de célula vermelha sanguínea |
| AU2014216178B2 (en) | 2013-02-15 | 2018-06-28 | KALA BIO, Inc. | Therapeutic compounds and uses thereof |
| US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
| ES2831625T3 (es) | 2013-02-20 | 2021-06-09 | Kala Pharmaceuticals Inc | Compuestos terapéuticos y sus usos |
| KR20160099084A (ko) | 2013-11-01 | 2016-08-19 | 칼라 파마슈티컬스, 인크. | 치료 화합물의 결정질 형태 및 그의 용도 |
| US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| CN104788373A (zh) * | 2015-05-06 | 2015-07-22 | 武汉大学 | 化合物s-303盐酸盐的合成方法 |
| AU2016283389B2 (en) | 2015-06-26 | 2022-09-15 | Cerus Corporation | Cryoprecipitate compositions and methods of preparation thereof |
| CN104991033A (zh) * | 2015-08-05 | 2015-10-21 | 上海海虹实业(集团)巢湖今辰药业有限公司 | 一种采用一测多评法测定川芎挥发油成分的方法 |
| US10799533B2 (en) | 2015-10-23 | 2020-10-13 | Cerus Corporation | Plasma compositions and methods of use thereof |
| US10392399B2 (en) | 2016-09-08 | 2019-08-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| CA3036336A1 (en) | 2016-09-08 | 2018-03-15 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
| JP2019533641A (ja) | 2016-09-08 | 2019-11-21 | カラ ファーマシューティカルズ インコーポレイテッド | 治療用化合物の結晶形態およびその使用 |
| EP3559665A1 (de) * | 2016-12-23 | 2019-10-30 | Cerus Corporation | Systeme und verfahren für tests und screenings unter verwendung von substraten mit daran gebundenen verbindungen |
| BR112019018273A2 (pt) | 2017-03-03 | 2020-07-14 | Cerus Corporation | kits e métodos para preparação de composições de plaquetas inativadas por patógenos |
| CA3087253A1 (en) | 2017-12-29 | 2019-07-04 | Cerus Corporation | Systems and methods for treating biological fluids |
| MX2021015653A (es) | 2019-06-22 | 2022-04-11 | Cerus Corp | Sistemas de tratamiento de fluidos biologicos. |
| AU2020308035A1 (en) | 2019-06-28 | 2022-02-17 | Cerus Corporation | System and methods for implementing a biological fluid treatment device |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994020090A1 (en) * | 1993-03-17 | 1994-09-15 | Steritech, Inc. | Decontaminating clinical samples |
| US5691132A (en) * | 1994-11-14 | 1997-11-25 | Cerus Corporation | Method for inactivating pathogens in red cell compositions using quinacrine mustard |
| DE4444045C2 (de) * | 1994-12-10 | 1997-04-17 | Behringwerke Ag | Verfahren zur Inaktivierung von Viren mit Hilfe von Acridin oder Acridinderivaten |
| AU722811B2 (en) * | 1995-06-07 | 2000-08-10 | Cerus Corporation | Treating red blood cell solutions with anti-viral agents |
| ES2196530T3 (es) * | 1997-01-06 | 2003-12-16 | Cerus Corp | Compuestos de ruptura para inactivar patogenos. |
-
1998
- 1998-01-06 ES ES98901776T patent/ES2196530T3/es not_active Expired - Lifetime
- 1998-01-06 WO PCT/US1998/000532 patent/WO1998030545A1/en active IP Right Grant
- 1998-01-06 AU AU58217/98A patent/AU744089C/en not_active Expired
- 1998-01-06 CN CN988027348A patent/CN1248245B/zh not_active Expired - Lifetime
- 1998-01-06 CA CA002276532A patent/CA2276532C/en not_active Expired - Fee Related
- 1998-01-06 DE DE69815703T patent/DE69815703T2/de not_active Expired - Lifetime
- 1998-01-06 EP EP98901776A patent/EP1021414B1/de not_active Expired - Lifetime
- 1998-01-06 JP JP53119998A patent/JP4551502B2/ja not_active Expired - Lifetime
- 1998-01-06 CN CN2009101633119A patent/CN101676268B/zh not_active Expired - Lifetime
- 1998-01-06 AT AT98901776T patent/ATE243198T1/de not_active IP Right Cessation
-
2000
- 2000-09-20 HK HK00105911.5A patent/HK1026702A1/xx not_active IP Right Cessation
- 2000-09-20 HK HK10109160.3A patent/HK1188441A1/xx not_active IP Right Cessation
-
2009
- 2009-12-17 JP JP2009286996A patent/JP5244083B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1021414B1 (de) | 2003-06-18 |
| DE69815703D1 (de) | 2003-07-24 |
| HK1188441A1 (en) | 2014-05-02 |
| AU744089C (en) | 2003-07-31 |
| AU5821798A (en) | 1998-08-03 |
| JP4551502B2 (ja) | 2010-09-29 |
| JP2010095527A (ja) | 2010-04-30 |
| CN101676268A (zh) | 2010-03-24 |
| HK1026702A1 (en) | 2000-12-22 |
| CN1248245B (zh) | 2012-07-04 |
| DE69815703T2 (de) | 2004-06-03 |
| JP2001508449A (ja) | 2001-06-26 |
| WO1998030545A1 (en) | 1998-07-16 |
| CN1248245A (zh) | 2000-03-22 |
| ES2196530T3 (es) | 2003-12-16 |
| EP1021414A1 (de) | 2000-07-26 |
| JP5244083B2 (ja) | 2013-07-24 |
| CA2276532C (en) | 2008-06-17 |
| CA2276532A1 (en) | 1998-07-16 |
| AU744089B2 (en) | 2002-02-14 |
| CN101676268B (zh) | 2013-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |