ATE113591T1 - 4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol- - one und ihre verwendung als antikonvulsiva. - Google Patents

4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol- - one und ihre verwendung als antikonvulsiva.

Info

Publication number: ATE113591T1
Authority: AT; Austria
Prior art keywords: anticonvulsants; dihydro; benzyl; phenyl; triazole
Prior art date: 1989-12-20

Application number

AT90124971T

Other languages

English (en)

Inventor

John M Kane

Francis P Miller

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-20

Filing date

1990-12-20

Publication date

1994-11-15

1990-12-20 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1994-11-15 Application granted granted Critical

1994-11-15 Publication of ATE113591T1 publication Critical patent/ATE113591T1/de

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT90124971T 1989-12-20 1990-12-20 4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol- - one und ihre verwendung als antikonvulsiva. ATE113591T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/453,440 US4966909A (en)	1989-12-20	1989-12-20	4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants

Publications (1)

Publication Number	Publication Date
ATE113591T1 true ATE113591T1 (de)	1994-11-15

Family

ID=23800598

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90124971T ATE113591T1 (de)	1989-12-20	1990-12-20	4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol- - one und ihre verwendung als antikonvulsiva.

Country Status (12)

Country	Link
US (1)	US4966909A (de)
EP (1)	EP0435177B1 (de)
JP (1)	JP2968053B2 (de)
KR (1)	KR0154529B1 (de)
AT (1)	ATE113591T1 (de)
AU (1)	AU634003B2 (de)
DE (1)	DE69013871T2 (de)
DK (1)	DK0435177T3 (de)
ES (1)	ES2066096T3 (de)
IE (1)	IE64989B1 (de)
PH (1)	PH27352A (de)
ZA (1)	ZA9010080B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4966909A (en) *	1989-12-20	1990-10-30	Merrell Dow Pharmaceuticals	4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants
SE470120B (sv) *	1992-04-03	1993-11-08	Whirlpool Int	Förfarande för styrning av mikrovågsenergin i en mikrovågsugn och mikrovågsugn för genomförande av förfarandet
CA2216787C (en) *	1995-04-20	2001-05-22	Hoechst Marion Roussel, Inc.	3-phenyl-1,4-dialkyl-1,2,4-triazolium salts and their use as antidepressants
TW467902B (en) *	1996-07-31	2001-12-11	Bristol Myers Squibb Co	Diphenyl heterocycles as potassium channel modulators
US6489487B1 (en) *	1998-08-03	2002-12-03	Sumitomo Chemical Company, Limited	Triazolone derivatives, use thereof, and intermediates therefor
US6156775A (en) *	1999-03-01	2000-12-05	Novartis Ag	Use of fluorinated triazoles in treating affective and attention disorders
TW200505441A (en)	2003-03-24	2005-02-16	Hoffmann La Roche	Non-nucleoside reverse transcriptase inhibitorsⅠ
US7400548B2 (en) *	2005-02-09	2008-07-15	International Business Machines Corporation	Method for providing multiple reads/writes using a 2read/2write register file array
BRPI0809617A2 (pt)	2007-03-29	2014-09-16	Hoffmann La Roche	Inibidores não-nucleosídicos da transcriptase reversa
JP2022189000A (ja)	2021-06-10	2022-12-22	Ｔｍｔマシナリー株式会社	紡糸引取装置

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1126882B (de) *	1960-05-03	1962-04-05	Boehringer Sohn Ingelheim	Verfahren zur Herstellung von 1,2,4-Triazolonen-(5)
BE621842A (de) *	1962-08-27
GB1068083A (en) *	1964-04-02	1967-05-10	Philippe Gold Aubert	í¸-1,2,4-triazolone-(5) derivatives
US3621099A (en) *	1969-03-05	1971-11-16	Charles R Jacobson	Therapeutic compositions and methods for stimulating the central nervous system
DE3173083D1 (en) *	1980-03-22	1986-01-16	Fbc Ltd	Pesticidal heterocyclic compounds, processes for preparing them, compositions containing them, and their use
DD153953A3 (de) *	1980-04-01	1982-02-17	Gottfried Schuster	Mittel zur chemotherapie von virosen der kulturpflanzen
DD160447A1 (de) *	1981-03-26	1983-08-03	Johannes Dost	Herbizide mittel, die 1,2,4-triazolinone-(5) enthalten
BE894856A (fr) *	1982-10-28	1983-02-14	Fahlberg List Veb	Compositions herbicides a base d'un derive de la 1,2,4-triazolinone-(5)
PH24094A (en) *	1986-12-19	1990-03-05	Merrell Dow Pharma	5-aryl-3h-1,2,4-triazol-3-ones and their use as anticonvulsants
JP2593084B2 (ja) *	1986-12-19	1997-03-19	メレルダウファーマスーティカルズインコーポレーテッド	５−アリールー３ｈ−１，２，４−トリアゾールー３−オン類の神経変性障害の処置への用途
US4966909A (en) *	1989-12-20	1990-10-30	Merrell Dow Pharmaceuticals	4-benzyl-5-phenyl-2,4-dihydro-3H-1,2,4-triazol-3-ones and their use as anticonvulsants

1989
- 1989-12-20 US US07/453,440 patent/US4966909A/en not_active Expired - Fee Related
1990
- 1990-12-14 ZA ZA9010080A patent/ZA9010080B/xx unknown
- 1990-12-14 AU AU68081/90A patent/AU634003B2/en not_active Ceased
- 1990-12-19 KR KR1019900021073A patent/KR0154529B1/ko not_active IP Right Cessation
- 1990-12-19 IE IE459990A patent/IE64989B1/en not_active IP Right Cessation
- 1990-12-19 JP JP2411704A patent/JP2968053B2/ja not_active Expired - Fee Related
- 1990-12-20 AT AT90124971T patent/ATE113591T1/de not_active IP Right Cessation
- 1990-12-20 PH PH41759A patent/PH27352A/en unknown
- 1990-12-20 EP EP90124971A patent/EP0435177B1/de not_active Expired - Lifetime
- 1990-12-20 DE DE69013871T patent/DE69013871T2/de not_active Expired - Fee Related
- 1990-12-20 DK DK90124971.4T patent/DK0435177T3/da active
- 1990-12-20 ES ES90124971T patent/ES2066096T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES2066096T3 (es)	1995-03-01
PH27352A (en)	1993-06-21
DK0435177T3 (da)	1994-11-21
EP0435177A3 (en)	1992-01-08
ZA9010080B (en)	1991-10-30
AU6808190A (en)	1991-06-27
DE69013871D1 (de)	1994-12-08
EP0435177B1 (de)	1994-11-02
KR910011807A (ko)	1991-08-07
IE904599A1 (en)	1991-07-03
JPH04128271A (ja)	1992-04-28
US4966909A (en)	1990-10-30
JP2968053B2 (ja)	1999-10-25
EP0435177A2 (de)	1991-07-03
AU634003B2 (en)	1993-02-11
IE64989B1 (en)	1995-09-20
DE69013871T2 (de)	1995-03-09
KR0154529B1 (ko)	1998-11-16

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Legal Events

Date	Code	Title	Description
2004-09-15	REN	Ceased due to non-payment of the annual fee