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ATE191345T1 - Arzneimittel zur behandlung von autoimmunerkrankungen - Google Patents

Arzneimittel zur behandlung von autoimmunerkrankungen

Info

Publication number
ATE191345T1
ATE191345T1 AT92924908T AT92924908T ATE191345T1 AT E191345 T1 ATE191345 T1 AT E191345T1 AT 92924908 T AT92924908 T AT 92924908T AT 92924908 T AT92924908 T AT 92924908T AT E191345 T1 ATE191345 T1 AT E191345T1
Authority
AT
Austria
Prior art keywords
thieno
triazolo
immunosuppression
chlorophenyl
dimethyl
Prior art date
Application number
AT92924908T
Other languages
English (en)
Inventor
Takeki Okumoto
Kenji Chiba
Yukio Hoshino
Hirotsugu Komatu
Mariko Nagasawa
Hidekazu Aratani
Michio Terasawa
Minoru Moriwaki
Original Assignee
Yoshitomi Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yoshitomi Pharmaceutical filed Critical Yoshitomi Pharmaceutical
Application granted granted Critical
Publication of ATE191345T1 publication Critical patent/ATE191345T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT92924908T 1991-12-11 1992-12-10 Arzneimittel zur behandlung von autoimmunerkrankungen ATE191345T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP35088991 1991-12-11
JP2484892 1992-01-14
JP5438292 1992-02-04
JP12945592 1992-04-21
PCT/JP1992/001619 WO1993012117A1 (fr) 1991-12-11 1992-12-10 Agent immunosuppresseur

Publications (1)

Publication Number Publication Date
ATE191345T1 true ATE191345T1 (de) 2000-04-15

Family

ID=27458207

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92924908T ATE191345T1 (de) 1991-12-11 1992-12-10 Arzneimittel zur behandlung von autoimmunerkrankungen

Country Status (8)

Country Link
US (1) US5686479A (de)
EP (1) EP0656361B1 (de)
AT (1) ATE191345T1 (de)
DE (1) DE69230891T2 (de)
DK (1) DK0656361T3 (de)
ES (1) ES2143993T3 (de)
GR (1) GR3033434T3 (de)
WO (1) WO1993012117A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994022872A1 (en) * 1993-03-30 1994-10-13 Yoshitomi Pharmaceutical Industries, Ltd. Cell adhesion inhibitor and thienotriazolodiazepine compound
DE69717160T2 (de) * 1996-09-13 2003-05-08 Mitsubishi Pharma Corp., Osaka Thienotriazolodiazepinverbindungen und ihre medizinischen anwendungen
CA2291735A1 (en) * 1997-05-27 1998-12-03 Takahiro Ogawa Israpafant-containing water-base preparations
JPH1180026A (ja) * 1997-09-02 1999-03-23 Yoshitomi Pharmaceut Ind Ltd 新規免疫抑制剤、その使用方法およびその同定方法
US6986740B2 (en) * 1998-11-02 2006-01-17 Xantech Pharmaceuticals, Inc. Ultrasound contrast using halogenated xanthenes
MXPA04006709A (es) * 2002-01-11 2004-10-04 Sankyo Co Derivados de aminoalcohol o derivados de acido fosfonico y composiciones farmaceuticas que los contienen.
JP2005272453A (ja) 2004-02-24 2005-10-06 Sankyo Co Ltd アミノアルコール化合物
US9249161B2 (en) 2010-12-02 2016-02-02 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
AR084070A1 (es) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc Inhibidores del bromodominio y usos de los mismos
US9422292B2 (en) 2011-05-04 2016-08-23 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
WO2012174487A2 (en) 2011-06-17 2012-12-20 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
US9624244B2 (en) 2012-06-06 2017-04-18 Constellation Pharmaceuticals, Inc. Benzo [B] isoxazoloazepine bromodomain inhibitors and uses thereof
TWI602820B (zh) 2012-06-06 2017-10-21 星宿藥物公司 溴域抑制劑及其用途
DK3157928T3 (da) 2014-06-20 2019-05-20 Constellation Pharmaceuticals Inc Krystallinske former af 2-((4s)-6-(4-chlorphenyl)-1-methyl-4h-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2039408T3 (es) * 1986-11-17 1993-10-01 Yoshitomi Pharmaceutical Industries, Ltd. Un procedimiento para preparar un compuesto de tienotriazolodiazepina.
US5221671A (en) * 1988-10-31 1993-06-22 Eisai Co., Ltd. Triazolo-1,4-diazepine derivatives and their use in pharmaceuticals
FI95708C (fi) * 1988-10-31 1996-03-11 Eisai Co Ltd Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
EP0368175A1 (de) * 1988-11-06 1990-05-16 Boehringer Ingelheim Kg 3S,7S-3-(Morpholinocarbonyl)-5-(2-chlorphenyl)-7,10-dimethyl-3,4-dihydro-2H,7H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin.
EP0387613A1 (de) * 1989-03-03 1990-09-19 Boehringer Ingelheim Kg Neue Thienodiazepine
US5212185A (en) * 1992-08-14 1993-05-18 G. D. Searle & Co. Piperidinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension

Also Published As

Publication number Publication date
EP0656361B1 (de) 2000-04-05
DE69230891D1 (de) 2000-05-11
US5686479A (en) 1997-11-11
EP0656361A4 (de) 1995-01-18
EP0656361A1 (de) 1995-06-07
GR3033434T3 (en) 2000-09-29
WO1993012117A1 (fr) 1993-06-24
DE69230891T2 (de) 2000-10-05
ES2143993T3 (es) 2000-06-01
DK0656361T3 (da) 2000-07-24

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee