ATE169917T1 - Imidazo (4,5-c)pyridinderivate als paf antagonisten - Google Patents
Imidazo (4,5-c)pyridinderivate als paf antagonistenInfo
- Publication number
- ATE169917T1 ATE169917T1 AT92915959T AT92915959T ATE169917T1 AT E169917 T1 ATE169917 T1 AT E169917T1 AT 92915959 T AT92915959 T AT 92915959T AT 92915959 T AT92915959 T AT 92915959T AT E169917 T1 ATE169917 T1 AT E169917T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- imidazo
- pyridine derivatives
- paf
- paf antagonists
- Prior art date
Links
- 239000005557 antagonist Substances 0.000 title abstract 2
- UBOOKRVGOBKDMM-UHFFFAOYSA-N 3h-imidazo[4,5-c]pyridine Chemical class C1=NC=C2NC=NC2=C1 UBOOKRVGOBKDMM-UHFFFAOYSA-N 0.000 title 1
- HVAUUPRFYPCOCA-AREMUKBSSA-N 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCCOC[C@@H](OC(C)=O)COP([O-])(=O)OCC[N+](C)(C)C HVAUUPRFYPCOCA-AREMUKBSSA-N 0.000 abstract 3
- 108010003541 Platelet Activating Factor Proteins 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919116056A GB9116056D0 (en) | 1991-07-24 | 1991-07-24 | Compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE169917T1 true ATE169917T1 (de) | 1998-09-15 |
Family
ID=10698952
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92915959T ATE169917T1 (de) | 1991-07-24 | 1992-07-24 | Imidazo (4,5-c)pyridinderivate als paf antagonisten |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5446032A (de) |
| EP (1) | EP0605434B1 (de) |
| AT (1) | ATE169917T1 (de) |
| DE (1) | DE69226703T2 (de) |
| GB (1) | GB9116056D0 (de) |
| WO (1) | WO1993002080A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9200209D0 (en) * | 1992-01-07 | 1992-02-26 | British Bio Technology | Compounds |
| GB9202791D0 (en) * | 1992-02-11 | 1992-03-25 | British Bio Technology | Compounds |
| GB0215293D0 (en) | 2002-07-03 | 2002-08-14 | Rega Foundation | Viral inhibitors |
| WO2004110992A2 (en) * | 2003-06-06 | 2004-12-23 | 3M Innovative Properties Company | Process for imidazo[4,5-c] pyridin-4-amines |
| NZ548074A (en) * | 2003-12-22 | 2010-08-27 | Gerhard Puerstinger | Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment |
| EP1841765B1 (de) * | 2004-12-21 | 2009-03-25 | Gilead Sciences, Inc. | Imidazo[4,5-c]pyridinverbindung und verfahren zur antiviralen behandlung |
| DE602007004220D1 (de) * | 2006-07-07 | 2010-02-25 | Leuven K U Res & Dev | Neue pyridazinverbindung und ihre verwendung |
| UA99466C2 (en) | 2007-07-06 | 2012-08-27 | Гилиад Сайенсиз, Инк. | Crystalline pyridazine compound |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4539332A (en) * | 1983-11-14 | 1985-09-03 | Merck & Co., Inc. | 2,5-Diaryl tetrahydrofurans and analogs thereof as PAF-antagonists |
| JP2556849B2 (ja) * | 1986-02-13 | 1996-11-27 | 三共株式会社 | グリセリン誘導体 |
| US4804658A (en) * | 1986-09-15 | 1989-02-14 | G. D. Searle & Co. | Imidazopyridine derivatives and pharmaceutical compositions |
| US4914108A (en) * | 1988-03-14 | 1990-04-03 | G. D. Searle & Co. | 5-substituted(4,5-c)imidazopyridine compounds which have useful platelet activating factor antagonistic activity |
| US5019581A (en) * | 1988-03-14 | 1991-05-28 | G. D. Searle & Co. | 5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity |
| EP0404797B1 (de) * | 1988-03-15 | 1995-02-01 | G.D. Searle & Co. | 1H/3H-[4-(N,N-CYCLOALKYL UND/ODER VERZWEIGTES ALKYLCARBOXAMIDO)-BENZYL]IMDAZO[4,5-c]PYRIDINE ALS PAF-ANTAGONISTEN |
| GB8904174D0 (en) * | 1989-02-23 | 1989-04-05 | British Bio Technology | Compounds |
| IE70217B1 (en) * | 1990-08-15 | 1996-10-30 | British Bio Technology | Benzimidazole derivatives process for their preparation and application |
-
1991
- 1991-07-24 GB GB919116056A patent/GB9116056D0/en active Pending
-
1992
- 1992-07-24 EP EP92915959A patent/EP0605434B1/de not_active Expired - Lifetime
- 1992-07-24 AT AT92915959T patent/ATE169917T1/de not_active IP Right Cessation
- 1992-07-24 US US08/185,815 patent/US5446032A/en not_active Expired - Fee Related
- 1992-07-24 WO PCT/GB1992/001370 patent/WO1993002080A1/en active IP Right Grant
- 1992-07-24 DE DE69226703T patent/DE69226703T2/de not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0605434A1 (de) | 1994-07-13 |
| EP0605434B1 (de) | 1998-08-19 |
| US5446032A (en) | 1995-08-29 |
| GB9116056D0 (en) | 1991-09-11 |
| DE69226703T2 (de) | 1999-02-18 |
| WO1993002080A1 (en) | 1993-02-04 |
| DE69226703D1 (de) | 1998-09-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |