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ATE163290T1 - Imidazol-verbindungen, verfahren zu ihrer herstellung und ihre anwendung - Google Patents

Imidazol-verbindungen, verfahren zu ihrer herstellung und ihre anwendung

Info

Publication number
ATE163290T1
ATE163290T1 AT92108983T AT92108983T ATE163290T1 AT E163290 T1 ATE163290 T1 AT E163290T1 AT 92108983 T AT92108983 T AT 92108983T AT 92108983 T AT92108983 T AT 92108983T AT E163290 T1 ATE163290 T1 AT E163290T1
Authority
AT
Austria
Prior art keywords
production
application
imidazole compounds
compounds
epilepsia
Prior art date
Application number
AT92108983T
Other languages
English (en)
Inventor
Oskar Axelsson
Mikkel Thaning
Peter Moldt
Original Assignee
Neurosearch As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch As filed Critical Neurosearch As
Application granted granted Critical
Publication of ATE163290T1 publication Critical patent/ATE163290T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Lubricants (AREA)
  • Eye Examination Apparatus (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
AT92108983T 1991-06-24 1992-05-27 Imidazol-verbindungen, verfahren zu ihrer herstellung und ihre anwendung ATE163290T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US72002191A 1991-06-24 1991-06-24

Publications (1)

Publication Number Publication Date
ATE163290T1 true ATE163290T1 (de) 1998-03-15

Family

ID=24892332

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92108983T ATE163290T1 (de) 1991-06-24 1992-05-27 Imidazol-verbindungen, verfahren zu ihrer herstellung und ihre anwendung

Country Status (14)

Country Link
EP (1) EP0520200B1 (de)
JP (1) JPH05186432A (de)
AT (1) ATE163290T1 (de)
AU (1) AU653816B2 (de)
CA (1) CA2071793A1 (de)
DE (1) DE69224448T2 (de)
DK (1) DK0520200T3 (de)
ES (1) ES2113898T3 (de)
FI (1) FI922905A (de)
GR (1) GR3026467T3 (de)
IE (1) IE921650A1 (de)
NO (1) NO302119B1 (de)
NZ (1) NZ242951A (de)
ZA (1) ZA924117B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK40192D0 (da) * 1992-03-26 1992-03-26 Neurosearch As Imidazolforbindelser, deres fremstilling og anvendelse
DK154092D0 (da) * 1992-12-23 1992-12-23 Neurosearch As Imidazolforbindelser, deres fremstilling og anvendelse
US5554630A (en) * 1993-03-24 1996-09-10 Neurosearch A/S Benzimidazole compounds
AU675484B2 (en) * 1993-03-24 1997-02-06 Neurosearch A/S Benzimidazole compounds, their use and preparation
US5496826A (en) * 1994-09-02 1996-03-05 Bristol-Myers Squibb Company Pharmaceutical methods of using heterocyclic derivatives of N-phenylamides
WO1996033191A1 (en) * 1995-04-21 1996-10-24 Neurosearch A/S Benzimidazole compounds and their use as modulators of the gabaa receptor complex
DE69833858T2 (de) * 1997-07-08 2007-02-22 Ono Pharmaceutical Co. Ltd. Aminosäurederivate
CN1283187A (zh) * 1997-12-22 2001-02-07 味之素株式会社 新颖二氢吡啶衍生物
TWI245035B (en) 1998-06-26 2005-12-11 Ono Pharmaceutical Co Amino acid derivatives and a pharmaceutical composition comprising the derivatives
US6194447B1 (en) 1998-07-02 2001-02-27 Neurosearch A/S Bis (benzimidazole) derivatives serving as potassium blocking agents
WO2000001676A1 (en) * 1998-07-02 2000-01-13 Neurosearch A/S Potassium channel blocking agents
WO2000004005A1 (fr) 1998-07-14 2000-01-27 Ono Pharmaceutical Co., Ltd. Derives acides amines et medicaments dont ces derives sont les principes actifs
AU4329499A (en) 1998-07-30 2000-02-21 Warner-Lambert Company Reduced dipeptide analogues as calcium channel antagonists
EP1191021A4 (de) 1999-06-23 2002-08-07 Ajinomoto Kk Dihydropyridin-derivat
US7115645B2 (en) 2000-01-14 2006-10-03 Schering Aktiengesellschaft 1,2 diarylbenzimidazoles and their pharmaceutical use
NZ519326A (en) * 2000-01-14 2005-02-25 Schering Ag 1,2-diarylbenzimidazoles for treating diseases that are associated with a microglia activation
US7329679B2 (en) 2000-01-27 2008-02-12 Schering Aktiengesellschaft 1,2 Diarylbenzimidazoles and their pharmaceutical use
DE10135050A1 (de) * 2001-07-09 2003-02-06 Schering Ag 1-Ary1-2-N-, S- oder O-substituierte Benzimidazolderivate, deren Verwendung zur Herstellung von Arzneimitteln sowie diese Derivate enthaltende pharmazeutische Präparate
KR100873400B1 (ko) * 2002-10-17 2008-12-11 한국과학기술연구원 Ｎ-타입 칼슘 채널의 활성을 억제함으로써 우울증을감소시키는 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4492708A (en) * 1982-09-27 1985-01-08 Eli Lilly And Company Antiviral benzimidazoles
JPS6474A (en) * 1987-01-29 1989-01-05 Otsuka Pharmaceut Factory Inc Benzimidazole derivative
JPH0772181B2 (ja) * 1989-06-26 1995-08-02 株式会社大塚製薬工場 ベンズイミダゾール誘導体
NZ239540A (en) * 1990-09-24 1993-11-25 Neurosearch As 1-phenyl benzimidazole derivatives and medicaments

Also Published As

Publication number Publication date
DK0520200T3 (da) 1998-09-23
NZ242951A (en) 1994-12-22
NO922475D0 (no) 1992-06-23
NO302119B1 (no) 1998-01-26
IE921650A1 (en) 1992-12-30
GR3026467T3 (en) 1998-06-30
AU1726792A (en) 1993-01-07
ZA924117B (en) 1993-03-31
FI922905A0 (fi) 1992-06-22
NO922475L (no) 1992-12-28
ES2113898T3 (es) 1998-05-16
FI922905A (fi) 1992-12-25
DE69224448T2 (de) 1998-06-10
JPH05186432A (ja) 1993-07-27
EP0520200B1 (de) 1998-02-18
AU653816B2 (en) 1994-10-13
CA2071793A1 (en) 1992-12-25
DE69224448D1 (de) 1998-03-26
EP0520200A2 (de) 1992-12-30
EP0520200A3 (en) 1993-05-12

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