ATA483273A - Verfahren zur herstellung von neuen n-benzhydryl-n'-p-hydroxybenzyl-piperazinen und ihren salzen - Google Patents

Verfahren zur herstellung von neuen n-benzhydryl-n'-p-hydroxybenzyl-piperazinen und ihren salzen

Info

Publication number: ATA483273A
Authority: AT; Austria
Prior art keywords: piperazines; benzhydryl; hydroxybenzyl; salts; preparation
Prior art date: 1972-06-02

Application number

AT483273A

Other languages

English (en)

Other versions

AT331252B (de

Original Assignee

Cassella Farbwerke Mainkur Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1972-06-02

Filing date

1973-06-01

Publication date

1975-11-15

1972-06-02 Priority claimed from DE2226767A external-priority patent/DE2226767A1/de

1973-03-12 Priority claimed from DE19732312212 external-priority patent/DE2312212A1/de

1973-06-01 Application filed by Cassella Farbwerke Mainkur Ag filed Critical Cassella Farbwerke Mainkur Ag

1975-11-15 Publication of ATA483273A publication Critical patent/ATA483273A/de

1976-08-10 Application granted granted Critical

1976-08-10 Publication of AT331252B publication Critical patent/AT331252B/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/03—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to acyclic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Catalysts (AREA)
Hydrogenated Pyridines (AREA)

AT483273A 1972-06-02 1973-06-01 Verfahren zur herstellung von neuen n-benzhydryl-n'-p-hydroxybenzyl-piperazinen und ihren salzen AT331252B (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE2226767A DE2226767A1 (de)	1972-06-02	1972-06-02	N-benzhydryl-n'-p-hydroxybenzylpiperazin und verfahren zu seiner herstellung
DE19732312212 DE2312212A1 (de)	1973-03-12	1973-03-12	N-(p-chlorbenzhydryl)-n'-p-hydroxybenzyl-piperazin und verfahren zu seiner herstellung

Publications (2)

Publication Number	Publication Date
ATA483273A true ATA483273A (de)	1975-11-15
AT331252B AT331252B (de)	1976-08-10

Family

ID=25763357

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AT483273A AT331252B (de)	1972-06-02	1973-06-01	Verfahren zur herstellung von neuen n-benzhydryl-n'-p-hydroxybenzyl-piperazinen und ihren salzen
AT483173A AT331802B (de)	1972-06-02	1973-06-01	Verfahren zur herstellung von neuen n-benzhydryl-n'-p-hydroxybenzyl-piperazinen und ihren saureadditionssalzen
AT483073A AT331801B (de)	1972-06-02	1973-06-01	Verfahren zur herstellung von neuen n-benzhydryl-n'-p-hydroxybenzyl-piperazinen und ihren saureadditionssalzen

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
AT483173A AT331802B (de)	1972-06-02	1973-06-01	Verfahren zur herstellung von neuen n-benzhydryl-n'-p-hydroxybenzyl-piperazinen und ihren saureadditionssalzen
AT483073A AT331801B (de)	1972-06-02	1973-06-01	Verfahren zur herstellung von neuen n-benzhydryl-n'-p-hydroxybenzyl-piperazinen und ihren saureadditionssalzen

Country Status (26)

Country	Link
US (1)	US3868377A (de)
JP (1)	JPS4948687A (de)
AR (5)	AR196936A1 (de)
AT (3)	AT331252B (de)
AU (1)	AU470393B2 (de)
BG (3)	BG20371A3 (de)
CA (1)	CA980347A (de)
CH (4)	CH579064A5 (de)
CS (4)	CS178429B2 (de)
DD (1)	DD106644A5 (de)
DK (1)	DK139751C (de)
EG (1)	EG11434A (de)
ES (3)	ES415466A1 (de)
FI (1)	FI55656C (de)
FR (1)	FR2186265B1 (de)
GB (1)	GB1386916A (de)
HU (1)	HU165312B (de)
IE (1)	IE37717B1 (de)
IL (1)	IL42384A (de)
NL (1)	NL7306771A (de)
NO (1)	NO138026C (de)
PH (1)	PH9485A (de)
PL (3)	PL94759B1 (de)
RO (3)	RO68379A (de)
SE (1)	SE396385B (de)
SU (4)	SU508196A3 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS59101475A (ja) *	1982-12-02	1984-06-12	Nippon Chemiphar Co Ltd	新規ピペラジン誘導体およびその製造法ならびにこれを含有する脳循環改善剤
HU186656B (en) *	1982-12-28	1985-09-30	Richter Gedeon Vegyeszet	Process for producing new benzhydryl-piperazine derivatives, acid additionak salts and pharmaceutical compositions containing them
GB8320701D0 (en) *	1983-08-01	1983-09-01	Wellcome Found	Chemotherapeutic agent
JPS60222472A (ja) *	1984-03-30	1985-11-07	Kanebo Ltd	新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物
ATE107296T1 (de) *	1988-08-05	1994-07-15	Nippon Chemiphar Co	Optisch aktive piperazin-derivate.
FR2661176B1 (fr) *	1990-04-20	1992-06-12	Adir	Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive.
EP0682664B1 (de) *	1993-12-08	2001-03-14	Alcon Laboratories, Inc.	Verbindungen die sowohl starke calcium-antagonistische und antioxydatieve aktivitaet haben und deren verwendung als zellschuetzende mittel.
CA2724887A1 (en) *	2008-06-02	2009-12-10	Cipla Limited	Processes for the synthesis of levocetirizine and intermediates for use therein

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2709169A (en) *		1955-05-24		X c chs
US3051710A (en) *	1959-12-21	1962-08-28	Lakeside Lab Inc	Glycolic acid amide derivatives of piperazine and use thereof

1973
- 1973-05-15 NL NL7306771A patent/NL7306771A/xx not_active Application Discontinuation
- 1973-05-28 IE IE855/73A patent/IE37717B1/xx unknown
- 1973-05-29 IL IL42384A patent/IL42384A/en unknown
- 1973-05-29 RO RO7382540A patent/RO68379A/ro unknown
- 1973-05-29 BG BG026973A patent/BG20371A3/xx unknown
- 1973-05-29 US US364764A patent/US3868377A/en not_active Expired - Lifetime
- 1973-05-29 RO RO7382539A patent/RO68378A/ro unknown
- 1973-05-29 RO RO7374944A patent/RO62900A/ro unknown
- 1973-05-29 BG BG023741A patent/BG20595A3/xx unknown
- 1973-05-29 BG BG026972A patent/BG20596A3/xx unknown
- 1973-05-29 CS CS3877A patent/CS178429B2/cs unknown
- 1973-05-29 CS CS7300003883A patent/CS182234B2/cs unknown
- 1973-05-29 CS CS3878A patent/CS178430B2/cs unknown
- 1973-05-29 CS CS7600004284A patent/CS182248B2/cs unknown
- 1973-05-30 SE SE7307692A patent/SE396385B/xx unknown
- 1973-05-30 GB GB2571073A patent/GB1386916A/en not_active Expired
- 1973-05-31 PL PL1973186639A patent/PL94759B1/pl unknown
- 1973-05-31 SU SU1926943A patent/SU508196A3/ru active
- 1973-05-31 PL PL1973186638A patent/PL97129B1/pl unknown
- 1973-05-31 AR AR248325A patent/AR196936A1/es active
- 1973-05-31 HU HUCA347A patent/HU165312B/hu unknown
- 1973-05-31 SU SU1926939A patent/SU507238A3/ru active
- 1973-05-31 PL PL1973162986A patent/PL91050B1/pl unknown
- 1973-05-31 DD DD171224A patent/DD106644A5/xx unknown
- 1973-05-31 EG EG206/73A patent/EG11434A/xx active
- 1973-05-31 PH PH14678*UA patent/PH9485A/en unknown
- 1973-05-31 SU SU1926942A patent/SU530644A3/ru active
- 1973-05-31 AR AR248326A patent/AR194688A1/es active
- 1973-05-31 JP JP48060375A patent/JPS4948687A/ja active Pending
- 1973-05-31 AR AR248327A patent/AR201001A1/es active
- 1973-05-31 CA CA172,824A patent/CA980347A/en not_active Expired
- 1973-05-31 AU AU56343/73A patent/AU470393B2/en not_active Expired
- 1973-06-01 ES ES415466A patent/ES415466A1/es not_active Expired
- 1973-06-01 NO NO2303/73A patent/NO138026C/no unknown
- 1973-06-01 ES ES73415465A patent/ES415465A1/es not_active Expired
- 1973-06-01 FI FI1797/73A patent/FI55656C/fi active
- 1973-06-01 AT AT483273A patent/AT331252B/de not_active IP Right Cessation
- 1973-06-01 DK DK304673A patent/DK139751C/da active
- 1973-06-01 AT AT483173A patent/AT331802B/de not_active IP Right Cessation
- 1973-06-01 FR FR7319998A patent/FR2186265B1/fr not_active Expired
- 1973-06-01 AT AT483073A patent/AT331801B/de not_active IP Right Cessation
- 1973-06-01 ES ES415464A patent/ES415464A1/es not_active Expired
- 1973-06-04 CH CH802973A patent/CH579064A5/xx not_active IP Right Cessation
- 1973-06-04 CH CH802873A patent/CH574949A5/xx not_active IP Right Cessation
- 1973-06-04 CH CH1193576A patent/CH594651A5/xx not_active IP Right Cessation
- 1973-06-04 CH CH803073A patent/CH593959A5/xx not_active IP Right Cessation
1974
- 1974-01-01 AR AR252417A patent/AR204987A1/es active
- 1974-02-18 AR AR252416A patent/AR200764A1/es active
- 1974-12-13 SU SU7402082532A patent/SU577995A3/ru active

Also Published As

Publication number	Publication date
SU508196A3 (ru)	1976-03-25
NO138026C (no)	1978-06-14
SU577995A3 (ru)	1977-10-25
SU507238A3 (ru)	1976-03-15
AR194688A1 (es)	1973-07-31
AR201001A1 (es)	1975-02-06
ES415466A1 (es)	1976-05-16
ATA483173A (de)	1975-12-15
DK139751B (da)	1979-04-09
FR2186265A1 (de)	1974-01-11
US3868377A (en)	1975-02-25
AT331802B (de)	1976-08-25
AU5634373A (en)	1974-12-05
PL94759B1 (pl)	1977-08-31
ES415465A1 (es)	1976-05-16
IE37717L (en)	1973-12-02
JPS4948687A (de)	1974-05-11
SU530644A3 (ru)	1976-09-30
BG20596A3 (bg)	1975-12-05
CS178429B2 (de)	1977-09-15
CS182234B2 (en)	1978-04-28
BG20595A3 (bg)	1975-12-05
FR2186265B1 (de)	1976-03-05
HU165312B (de)	1974-08-28
NL7306771A (de)	1973-12-04
AR196936A1 (es)	1974-02-28
AR204987A1 (es)	1976-03-31
PL97129B1 (pl)	1978-02-28
RO68378A (ro)	1982-02-01
CA980347A (en)	1975-12-23
CH594651A5 (de)	1978-01-13
DD106644A5 (de)	1974-06-20
CH579064A5 (de)	1976-08-31
ATA483073A (de)	1975-12-15
CS182248B2 (en)	1978-04-28
DK139751C (da)	1979-09-17
CH593959A5 (de)	1977-12-30
IE37717B1 (en)	1977-09-28
RO62900A (ro)	1982-10-26
RO68379A (ro)	1981-11-24
AR200764A1 (es)	1974-12-13
SE396385B (sv)	1977-09-19
FI55656B (fi)	1979-05-31
EG11434A (en)	1977-09-30
ES415464A1 (es)	1976-05-01
CS178430B2 (de)	1977-09-15
GB1386916A (en)	1975-03-12
IL42384A (en)	1976-12-31
PL91050B1 (de)	1977-02-28
IL42384A0 (en)	1973-07-30
CH574949A5 (de)	1976-04-30
PH9485A (en)	1976-01-08
BG20371A3 (bg)	1975-11-05
AT331252B (de)	1976-08-10
NO138026B (no)	1978-03-06
AT331801B (de)	1976-08-25
FI55656C (fi)	1979-09-10
AU470393B2 (en)	1976-03-11

Publication	Publication Date	Title
AT321277B (de)	1975-03-25	Verfahren zur Herstellung von neuen 1,3-Diphenyl-propan-1-onen und ihren Salzen
AT315831B (de)	1974-06-10	Verfahren zur Herstellung von neuen 4-Aza-benzimidazolderivaten und ihren Salzen
AT303024B (de)	1972-11-10	Verfahren zur Herstellung von neuen Aminophenyl-cycloamidinen und ihren Salzen
AT331794B (de)	1976-08-25	Verfahren zur herstellung von neuen 3,4-dihydro-2h-pyran-2,4-dionen und ihren salzen
AT331252B (de)	1976-08-10	Verfahren zur herstellung von neuen n-benzhydryl-n'-p-hydroxybenzyl-piperazinen und ihren salzen
AT323738B (de)	1975-07-25	Verfahren zur herstellung von neuen anilinobenzothiazolderivaten und ihren salzen
AT324325B (de)	1975-08-25	Verfahren zur herstellung von neuen 1-äthyl-imidazolen und ihren salzen
AT322548B (de)	1975-05-26	Verfahren zur herstellung von neuen 2-(aminophenylimino)-3-aza-1-thiacycloalkanderivaten und ihren salzen
AT338795B (de)	1977-09-12	Verfahren zur herstellung von neuen 4'-alkyldioxyalkylen-5-benzylpyrimidinen und ihren saureadditionssalzen
AT328455B (de)	1976-03-25	Verfahren zur herstellung von neuen nitroimidazolylpyrimidinderivaten und ihren salzen
AT312600B (de)	1974-01-10	Verfahren zur Herstellung von neuen 5-Nitrothiazolderivaten und ihren Salzen
AT303749B (de)	1972-12-11	Verfahren zur Herstellung von neuen 3,4-Dihydro-oxathiazin-4-on-2,2-dioxyden und ihren Salzen
AT306741B (de)	1973-04-25	Verfahren zur Herstellung von neuen 3-Guanidinoalkyl-thiophenen und ihren Salzen
AT329567B (de)	1976-05-25	Verfahren zur herstellung von neuen homopyrimidazolderivaten und ihren salzen
AT308760B (de)	1973-07-25	Verfahren zur Herstellung von neuen Pyridazon-6-iminen und ihren Salzen
AT342044B (de)	1978-03-10	Verfahren zur herstellung von neuen 2-carbalkoxy- oder 2-carbaroxy-amino-benzimidazol-5 (6)-phenylathern und ihren salzen
AT311961B (de)	1973-12-10	Verfahren zur Herstellung von neuen 2-Arylimino-thiazolidinen und ihren Salzen
AT320636B (de)	1975-02-25	Verfahren zur Herstellung von neuen Phenylimidazolidinonderivaten und ihren Salzen
ATA627275A (de)	1978-05-15	Verfahren zur herstellung von neuen aminopyrazoloisochinolinderivaten und ihren salzen
ATA627375A (de)	1977-10-15	Verfahren zur herstellung von neuen aminopyrazoloisochinolinderivaten und ihren salzen
ATA97674A (de)	1975-06-15	Verfahren zur herstellung von neuen phenylimidazolidinonderivaten und ihren salzen
ATA97874A (de)	1975-06-15	Verfahren zur herstellung von neuen phenylimidazolidinonderivaten und ihren salzen
ATA97774A (de)	1975-06-15	Verfahren zur herstellung von neuen phenylimidazolidinonderivaten und ihren salzen
AT313269B (de)	1974-02-11	Verfahren zur Herstellung von neuen 2-Iminopyrrolidinen und ihren Salzen
AT319945B (de)	1975-01-10	Verfahren zur Herstellung von neuen Dihydro-2-aminoisochinolinen und ihren Salzen

Legal Events

Date	Code	Title	Description
1979-03-15	EFA	Change in the company name
1981-08-15	ELJ	Ceased due to non-payment of the annual fee