AR240807A1 - PROCEDURE FOR OBTAINING DERIVATIVES OF BENZAZEPIN-2-ONA AND ITS SALTS - Google Patents

PROCEDURE FOR OBTAINING DERIVATIVES OF BENZAZEPIN-2-ONA AND ITS SALTS

Info

Publication number: AR240807A1
Authority: AR; Argentina
Prior art keywords: benzazepin; ona; salts; procedure; obtaining derivatives
Prior art date: 1981-08-11

Application number

AR295866A

Other languages

Spanish (es)

Other versions

AR240807A2 (en

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-08-11

Filing date

1984-02-28

Publication date

1991-02-28

1984-02-28 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1991-02-28 Application granted granted Critical

1991-02-28 Publication of AR240807A1 publication Critical patent/AR240807A1/en

1991-02-28 Publication of AR240807A2 publication Critical patent/AR240807A2/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06086—Dipeptides with the first amino acid being basic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AR295866A 1981-08-11 1984-02-28 PROCEDURE FOR OBTAINING DERIVATIVES OF BENZAZEPIN-2-ONA AND ITS SALTS AR240807A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US29190781A	1981-08-11	1981-08-11
US31986381A	1981-11-09	1981-11-09

Publications (2)

Publication Number	Publication Date
AR240807A1 true AR240807A1 (en)	1991-02-28
AR240807A2 AR240807A2 (en)	1991-02-28

Family

ID=26967047

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AR290295A AR240806A1 (en)	1981-08-11	1982-08-11	PROCEDURE FOR THE PREPARATION OF 3-AMINO- (1) BENZAZEPIN-2-ONA-1-ALKANOIC ACIDS AND ITS SALTS.
AR84295865A AR241222A1 (en)	1981-08-11	1984-02-28	Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and their therapeutical use
AR295866A AR240807A1 (en)	1981-08-11	1984-02-28	PROCEDURE FOR OBTAINING DERIVATIVES OF BENZAZEPIN-2-ONA AND ITS SALTS

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
AR290295A AR240806A1 (en)	1981-08-11	1982-08-11	PROCEDURE FOR THE PREPARATION OF 3-AMINO- (1) BENZAZEPIN-2-ONA-1-ALKANOIC ACIDS AND ITS SALTS.
AR84295865A AR241222A1 (en)	1981-08-11	1984-02-28	Benzazepin-2-ones, process for their preparation, pharmaceutical preparations containing these compounds and their therapeutical use

Country Status (22)

Country	Link
EP (1)	EP0072352B1 (en)
KR (3)	KR890003425B1 (en)
AR (3)	AR240806A1 (en)
AT (1)	ATE18397T1 (en)
AU (1)	AU561395B2 (en)
CA (1)	CA1196636A (en)
CY (1)	CY1403A (en)
DD (1)	DD202546A5 (en)
DE (1)	DE3269625D1 (en)
DK (1)	DK157881C (en)
ES (6)	ES514856A0 (en)
FI (1)	FI76074C (en)
GB (1)	GB2103614B (en)
GR (1)	GR77256B (en)
HK (1)	HK93387A (en)
HU (1)	HU189628B (en)
IE (1)	IE53668B1 (en)
IL (1)	IL66501A (en)
NL (1)	NL930112I2 (en)
NO (1)	NO161558C (en)
NZ (1)	NZ201555A (en)
PT (1)	PT75395B (en)

Families Citing this family (48)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3242599A1 (en) *	1982-11-18	1984-05-24	Dr. Karl Thomae Gmbh, 7950 Biberach	NEW BENZAZEPINE DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINAL PRODUCTS
US4473575A (en) *	1982-07-19	1984-09-25	Ciba-Geigy Corporation	3-Amino-(1)-benzazepin-2-one-1-alkanoic acids
EP0107095B1 (en) *	1982-09-30	1987-09-09	Merck & Co. Inc.	1-n-alkylcarboxy-benzofused lactams useful as antihypertensive agents
US4575503A (en) *	1983-02-10	1986-03-11	Ciba-Geigy Corporation	3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
US4564612A (en) *	1983-04-22	1986-01-14	Takeda Chemical Industries, Ltd.	Condensed, seven-membered ring compounds and their use
US4539150A (en) *	1983-06-29	1985-09-03	Mitsui Toatsu Chemicals, Inc.	Benzothiazepine derivatives and their methods of preparation
JPS608284A (en) *	1983-06-29	1985-01-17	Mitsui Toatsu Chem Inc	Benzothiazepine derivative and its preparation
IL72523A (en) *	1983-08-12	1988-06-30	Takeda Chemical Industries Ltd	3-amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine derivatives,their production and pharmaceutical compositions containing them
US4638000A (en) *	1983-08-12	1987-01-20	Takeda Chemical Industries, Ltd.	Condensed seven-membered ring compounds, their production and use
AU570710B2 (en) *	1983-08-12	1988-03-24	Takeda Chemical Industries Ltd.	4-oxo-2, 3, 4, 5-tetrahydro-1, 5-benzoxazepine derivatives
EP0166357A3 (en) *	1984-06-26	1988-10-26	Merck & Co. Inc.	Benzofused lactams and pharmaceutical compositions containing them
EP0166354B1 (en) *	1984-06-26	1992-08-05	Merck & Co. Inc.	Benzofused lactam compounds and pharmaceutical compositions containing them
CA1266647A (en) *	1984-06-26	1990-03-13	William H. Parsons	Benzofused lactams useful as antihypertensive agents and as cholecystokinin antagonists
US4785089A (en) *	1985-06-13	1988-11-15	Ciba-Geigy Corporation	Novel sulfonic acid esters and their preparation
DE3704661A1 (en) *	1987-02-14	1988-08-25	Hoechst Ag	FELECTED AZEPINONE AND AZOCINONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THEIR CONTAINERS AND THEIR USE, AND INTERMEDIATE PRODUCTS IN THEIR PRODUCTION
EP0322779A3 (en) *	1987-12-29	1991-05-08	Yoshitomi Pharmaceutical Industries, Ltd.	Benzolactam compounds and pharmaceutical uses thereof
TW197945B (en) *	1990-11-27	1993-01-11	Hoechst Ag
GB9100028D0 (en) *	1991-01-02	1991-02-20	Ici Plc	Compounds
GB9212308D0 (en) *	1992-06-10	1992-07-22	Ici Plc	Therapeutic compositions
US5504080A (en) *	1992-10-28	1996-04-02	Bristol-Myers Squibb Co.	Benzo-fused lactams
CA2151384A1 (en) *	1992-12-11	1994-06-23	Peter Buhlmayer	Benzazepinone derivatives
GB9310075D0 (en) *	1993-05-17	1993-06-30	Fujisawa Pharmaceutical Co	New mercapto-amide derivatives,processes for the preparation thereof and pharmaceutical composition comprising the same
GB9311948D0 (en) *	1993-06-10	1993-07-28	Zeneca Ltd	Substituted nitrogen heterocycles
US5801168A (en) *	1994-06-09	1998-09-01	Zeneca Limited	Substituted nitrogen heterocycles
US5597922A (en) *	1994-07-29	1997-01-28	State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon	Glycine receptor antagonist pharmacophore
EP1229913A4 (en) *	1999-11-18	2005-01-19	Antexpharma Inc	Substituted 1-benzazepines and derivatives thereof
CA2668823A1 (en)	2000-12-27	2002-07-04	Merck Patent Gesellschaft Mit Beschraenkter Haftung	Process for the preparation of .alpha.-aminosubstituted carboxylic acid amides
EP1383741A4 (en)	2001-03-27	2006-01-04	Ranbaxy Lab Ltd	Process for the preparation of benazepril
EP1443919A4 (en)	2001-11-16	2006-03-22	Bristol Myers Squibb Co	Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
AU2003250086A1 (en) *	2002-07-26	2004-02-23	Ciba Specialty Chemicals Holging Inc.	Crystalline polymorphic and amorphous forms of benazepril hydrochloride
KR100710548B1 (en) *	2002-12-26	2007-04-24	에스케이 주식회사	Method for preparing s-3-amino-2,3,4,5- tetrahydro-2-oxo-1H-1-benzazepin-1-acetic acid and ester compound thereof
US7459474B2 (en)	2003-06-11	2008-12-02	Bristol-Myers Squibb Company	Modulators of the glucocorticoid receptor and method
US8080579B2 (en)	2005-10-03	2011-12-20	The Regents Of The University Of Michigan	Compositions and methods for treatment of inflammatory bowel disease
US7592461B2 (en)	2005-12-21	2009-09-22	Bristol-Myers Squibb Company	Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
WO2008057862A2 (en)	2006-11-01	2008-05-15	Bristol-Myers Squibb Company	MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF
JP2010508358A (en)	2006-11-01	2010-03-18	ブリストル−マイヤーズスクイブカンパニー	Glucocorticoid receptor, AP-1 and / or modulator of NF-κB activity, and use thereof
JP5546451B2 (en)	2007-06-04	2014-07-09	シナジーファーマシューティカルズインコーポレイテッド	Agonyl cyclase agonists useful in the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en)	2007-06-04	2015-03-03	Synergy Pharmaceuticals, Inc.	Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US7828840B2 (en)	2007-11-15	2010-11-09	Med Institute, Inc.	Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists
EP2810951B1 (en)	2008-06-04	2017-03-15	Synergy Pharmaceuticals Inc.	Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CN102149710A (en)	2008-06-24	2011-08-10	百时美施贵宝公司	Cyclopentathiophene modulators of the glucocorticoid receptor, AP-1, and/or NF-Kappa B activity and use thereof
EP3241839B1 (en)	2008-07-16	2019-09-04	Bausch Health Ireland Limited	Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en)	2010-09-15	2017-04-11	Synergy Pharmaceuticals, Inc.	Formulations of guanylate cyclase C agonists and methods of use
JP2016514671A (en)	2013-03-15	2016-05-23	シナジーファーマシューティカルズインコーポレイテッド	Guanylate cyclase agonists and uses thereof
EP2968439A2 (en)	2013-03-15	2016-01-20	Synergy Pharmaceuticals Inc.	Compositions useful for the treatment of gastrointestinal disorders
EP4424697A2 (en)	2013-06-05	2024-09-04	Bausch Health Ireland Limited	Ultra-pure agonists of guanylate cyclase c, method of making and using same
WO2015027021A1 (en)	2013-08-22	2015-02-26	Bristol-Myers Squibb Company	Imide and acylurea derivatives as modulators of the glucocorticoid receptor
CN113292495B (en) *	2021-06-18	2022-09-13	迪嘉药业集团有限公司	Synthesis method of (S) -amino compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3395150A (en) *	1965-02-26	1968-07-30	Squibb & Sons Inc	Benzothiazepine carboxamides and derivatives thereof
GB1305278A (en) *	1970-03-12	1973-01-31

1982
- 1982-08-05 GB GB08222564A patent/GB2103614B/en not_active Expired
- 1982-08-05 CY CY140382A patent/CY1403A/en unknown
- 1982-08-05 DE DE8282810329T patent/DE3269625D1/en not_active Expired
- 1982-08-05 AT AT82810329T patent/ATE18397T1/en active
- 1982-08-05 EP EP82810329A patent/EP0072352B1/en not_active Expired
- 1982-08-09 FI FI822770A patent/FI76074C/en not_active IP Right Cessation
- 1982-08-09 ES ES514856A patent/ES514856A0/en active Granted
- 1982-08-09 GR GR68996A patent/GR77256B/el unknown
- 1982-08-09 IL IL66501A patent/IL66501A/en not_active IP Right Cessation
- 1982-08-09 CA CA000409019A patent/CA1196636A/en not_active Expired
- 1982-08-09 PT PT75395A patent/PT75395B/en unknown
- 1982-08-10 NO NO822722A patent/NO161558C/en not_active IP Right Cessation
- 1982-08-10 DD DD82242400A patent/DD202546A5/en not_active IP Right Cessation
- 1982-08-10 KR KR8203588A patent/KR890003425B1/en not_active IP Right Cessation
- 1982-08-10 IE IE1929/82A patent/IE53668B1/en not_active IP Right Cessation
- 1982-08-10 NZ NZ201555A patent/NZ201555A/en unknown
- 1982-08-10 AU AU87014/82A patent/AU561395B2/en not_active Expired
- 1982-08-10 HU HU822585A patent/HU189628B/en unknown
- 1982-08-10 DK DK358682A patent/DK157881C/en active
- 1982-08-11 AR AR290295A patent/AR240806A1/en active
1983
- 1983-10-28 ES ES526887A patent/ES8606285A1/en not_active Expired
- 1983-10-28 ES ES526886A patent/ES526886A0/en active Granted
- 1983-10-28 ES ES526888A patent/ES8504728A1/en not_active Expired
- 1983-10-28 ES ES526889A patent/ES8604523A1/en not_active Expired
1984
- 1984-02-28 AR AR84295865A patent/AR241222A1/en active
- 1984-02-28 AR AR295866A patent/AR240807A1/en active
- 1984-03-15 ES ES530658A patent/ES8602682A1/en not_active Expired
1987
- 1987-12-10 HK HK933/87A patent/HK93387A/en not_active IP Right Cessation
1989
- 1989-05-13 KR KR1019890006487A patent/KR900001191B1/en not_active IP Right Cessation
- 1989-05-13 KR KR8906486A patent/KR900001190B1/en not_active IP Right Cessation
1993
- 1993-06-29 NL NL930112C patent/NL930112I2/en unknown

Also Published As

Publication number	Publication date
NL930112I1 (en)	1993-10-18
NO161558B (en)	1989-05-22
ATE18397T1 (en)	1986-03-15
FI822770L (en)	1983-02-12
IL66501A0 (en)	1982-12-31
IE53668B1 (en)	1989-01-04
GB2103614B (en)	1984-11-21
AR240806A2 (en)	1991-02-28
ES8606285A1 (en)	1986-04-16
ES8604523A1 (en)	1986-02-01
IL66501A (en)	1987-10-20
EP0072352A1 (en)	1983-02-16
IE821929L (en)	1983-02-11
EP0072352B1 (en)	1986-03-05
GB2103614A (en)	1983-02-23
ES530658A0 (en)	1985-12-01
FI76074B (en)	1988-05-31
DK157881C (en)	1990-07-23
CY1403A (en)	1987-12-18
DK157881B (en)	1990-02-26
ES8502974A1 (en)	1985-02-01
ES8602682A1 (en)	1985-12-01
ES526888A0 (en)	1985-04-16
FI76074C (en)	1988-09-09
PT75395A (en)	1982-09-01
AU561395B2 (en)	1987-05-07
ES514856A0 (en)	1985-02-01
ES526889A0 (en)	1986-02-01
DE3269625D1 (en)	1986-04-10
PT75395B (en)	1985-11-15
GR77256B (en)	1984-09-11
KR900001190B1 (en)	1990-02-28
ES8504728A1 (en)	1985-04-16
HU189628B (en)	1986-07-28
KR900001191B1 (en)	1990-02-28
CA1196636A (en)	1985-11-12
NO822722L (en)	1983-02-14
AR241222A1 (en)	1992-02-28
NO161558C (en)	1989-08-30
NL930112I2 (en)	1996-11-01
KR840001139A (en)	1984-03-28
FI822770A0 (en)	1982-08-09
HK93387A (en)	1987-12-18
ES8601142A1 (en)	1985-11-01
NZ201555A (en)	1986-06-11
AR240806A1 (en)	1991-02-28
DD202546A5 (en)	1983-09-21
KR890003425B1 (en)	1989-09-20
ES526886A0 (en)	1985-11-01
AR240807A2 (en)	1991-02-28
AU8701482A (en)	1983-05-12
ES526887A0 (en)	1986-04-16
DK358682A (en)	1983-02-12

Publication	Publication Date	Title
AR240807A1 (en)	1991-02-28	PROCEDURE FOR OBTAINING DERIVATIVES OF BENZAZEPIN-2-ONA AND ITS SALTS
AR228575A1 (en)	1983-03-30	PROCEDURE FOR OBTAINING DERIVATIVES OF 7-HYDROXIMETIL OR 7-CARBOXICAMPTOTECINA AND ITS SALTS
AR229103A1 (en)	1983-06-15	PROCEDURE FOR THE PREPARATION OF DERIVATIVES OF 3-ARIL-5-ISOTIAZOLE AND ITS SALTS
AR228444A1 (en)	1983-03-15	PROCEDURE FOR PREPARING DERIVATIVES OF 5-BENCIL-TIAZOLIDIN-2,4-DIONA AND ITS SALTS
ES487464A0 (en)	1980-11-01	PROCEDURE FOR THE PREPARATION OF NEW PEPTIDIL-ARGININE ALDEHYDE DERIVATIVES AND THEIR SALTS
AR220686A1 (en)	1980-11-28	PROCEDURE FOR OBTAINING DERIVATIVES OF 2 AMINO-2-DESOXI-3-O- (PROPILCARBAMOILMETIL) -CARBAMOILMETIL-GLUCOPIRANOSA AND ITS SALTS
AR227731A1 (en)	1982-11-30	PROCEDURE TO OBTAIN NEW DERIVATIVES OF ((PIPERIDIL-2) -2-ETIL) -4-QUINOLEIN AND ITS SALTS
ES506222A0 (en)	1983-01-01	PROCEDURE FOR THE PREPARATION OF ACID AZABICICLOHEXANO CAR-BOXILICOS AND ITS SALTS
AR221080A1 (en)	1980-12-30	PROCEDURE FOR OBTAINING NEW DERIVATIVES OF PROPANONE AND ITS SALTS
AR230280A1 (en)	1984-03-01	PROCEDURE FOR OBTAINING CARBOESTIRILE DERIVATIVES AND THEIR SALTS
ES502643A0 (en)	1982-04-01	PROCEDURE FOR THE PREPARATION OF ARYL-PENYL-ACETYLENE COMPOUNDS AND THEIR AMMONIC SALTS
AR228144A1 (en)	1983-01-31	PROCEDURE FOR OBTAINING DERIVATIVES OF 5-PHENYL-TRIAZOLIDINE-2,4-DIONA AND ITS SALTS
AR240044A1 (en)	1990-01-31	PROCEDURE TO DEVELOP NEW DERIVATIVES OF QUINOLINONE AND ITS SALTS.
AR212468A1 (en)	1978-07-14	PROCEDURE FOR THE PREPARATION OF NEW W-ALKYLAMIDES DERIVATIVES OF W AMINO-CARBOXYL ACIDS AND THEIR SALTS
ES530269A0 (en)	1985-12-01	DERIVATIVES OF INDANO AND ITS SALTS
AR227272A1 (en)	1982-10-15	PROCEDURE FOR OBTAINING COMPOUNDS OF N-OXACICLIL-ALQUIL-PIPERIDIL-DIAZA AND ITS SALTS
AR218454A1 (en)	1980-06-13	PROCEDURE FOR PREPARING DERIVATIVES OF 7-BETA-AMINO OR 7-BETA- (2-OXIMINO-2-FURIL OR 2-PHENYLACETAMIDO) -3- (SULFOALQUIL OR 3-SULFOAMINALQUILO OR 3-SULFAMILALQUIL-TETRAZOL-5-IL) THOMETHYL 3 -CEFEM-4-CARBOXYLICS AND THEIR SALTS
AR231442A1 (en)	1984-11-30	PROCEDURE FOR OBTAINING NOVELTIES DERIVED FROM PIPERAZINO-2 PIRIMIDINE AND ITS SALTS
AR228036A1 (en)	1983-01-14	PROCEDURE FOR OBTAINING DERIVATIVES OF 1-TIO-ALCANOYLPROLIN AND ITS SALTS
AR224610A1 (en)	1981-12-30	PROCEDURE FOR OBTAINING DERIVATIVES, OF BENZACIL-BENZIMIDAZOLE-2-CARBOXYLIC ACIDS OR OF 2-HYDROXIMETILE AND ITS SALTS
ES545935A0 (en)	1986-06-01	PROCEDURE FOR PREPARING NEW DERIVATIVES OF DIHIDROPIRI-DINA AND ITS SALTS AND ESTERS
AR231538A1 (en)	1984-12-28	A PROCEDURE FOR OBTAINING DERIVATIVES OF 2-GUANIDINTIAZOLE AND ITS SALTS
AR228437A1 (en)	1983-03-15	PROCEDURE FOR PREPARING COMPOUNDS OF 6-PHENYL-2-OXO-NICOTINOYLAMOXICILLIN AND ITS SALTS
AR228039A1 (en)	1983-01-14	PROCEDURE FOR OBTAINING DERIVATIVES OF 2- (N'-FENILHIDRAZINO) -1-PIRROLINA AND ITS SALTS
ES512024A0 (en)	1983-06-01	DERIVATIVES OF ANILINE AND ITS SALTS.