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AR247884A1 - Procedure for preparing a derivative of 8-chloroquinolone which has a strong antimicrobe action and high grade of security - Google Patents

Procedure for preparing a derivative of 8-chloroquinolone which has a strong antimicrobe action and high grade of security

Info

Publication number
AR247884A1
AR247884A1 AR91320942A AR32094291A AR247884A1 AR 247884 A1 AR247884 A1 AR 247884A1 AR 91320942 A AR91320942 A AR 91320942A AR 32094291 A AR32094291 A AR 32094291A AR 247884 A1 AR247884 A1 AR 247884A1
Authority
AR
Argentina
Prior art keywords
chloroquinolone
derivative
antimicrobe
security
preparing
Prior art date
Application number
AR91320942A
Other languages
Spanish (es)
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of AR247884A1 publication Critical patent/AR247884A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PREPARACION DE UN DERIVADO DE 8-CLOROQUINOLONA, QUE TIENE UNA POTENTE ACTIVIDAD ANTIMICROBIANA Y ALTO GRADO DE SEGURIDAD, DE FORMULA (II), QUE COMPRENDE SOMETER UN COMPUESTO DE FORMULA (I), EN CUAL EL GRUPO AMINO SE HALLA PROTEGIDO A UNA REACCION DE CLORACION, CON CLORURO DE SULFURILO, CLORO O UN COMPUESTO DE FORMULA R4OCI EN DONDE R4 ES ALQUILO.PREPARATION OF A DERIVATIVE OF 8-CHLOROQUINOLONE, WHICH HAS A POWERFUL ANTIMICROBIAL ACTIVITY AND HIGH DEGREE OF SAFETY, OF FORMULA (II), WHICH INCLUDES SUBMITTING A COMPOUND OF FORMULA (I), IN WHICH THE AMINO GROUP IS FOUND PROTECTED FROM A REAC CHLORINATION, WITH SULFURYL CHLORIDE, CHLORINE OR A COMPOUND OF FORMULA R4OCI WHERE R4 IS RENT.

AR91320942A 1990-10-18 1991-10-17 Procedure for preparing a derivative of 8-chloroquinolone which has a strong antimicrobe action and high grade of security AR247884A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27977890 1990-10-18
JP22815391 1991-05-30

Publications (1)

Publication Number Publication Date
AR247884A1 true AR247884A1 (en) 1995-04-28

Family

ID=26528079

Family Applications (1)

Application Number Title Priority Date Filing Date
AR91320942A AR247884A1 (en) 1990-10-18 1991-10-17 Procedure for preparing a derivative of 8-chloroquinolone which has a strong antimicrobe action and high grade of security

Country Status (16)

Country Link
KR (1) KR100253047B1 (en)
CN (1) CN1038509C (en)
AR (1) AR247884A1 (en)
AT (1) AT402501B (en)
EE (1) EE03027B1 (en)
ES (1) ES2039300B1 (en)
FI (1) FI100531B (en)
GR (1) GR1000997B (en)
HU (1) HU221195B1 (en)
MX (1) MX9101668A (en)
MY (1) MY109714A (en)
NO (1) NO179517C (en)
PL (1) PL168831B1 (en)
PT (1) PT99268B (en)
RU (1) RU2049778C1 (en)
YU (1) YU48819B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0593766B1 (en) * 1991-05-28 2000-09-06 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivative
ZA946853B (en) * 1993-09-10 1995-04-24 Daiichi Seiyaku Co Crystals of antimicrobial compound.
CN1184221C (en) * 2001-08-08 2005-01-12 中国医学科学院医药生物技术研究所 New quinaldinic acid derivative with 7-(7-aminomethyl-5-azaspiro [2,4] heplane) substituent and its preparation method
CN103483315B (en) * 2013-09-18 2015-07-01 浙江司太立制药股份有限公司 7-(3-aminomethyl-4-alkoxyimino-1-piperidyl)-1-[(1R,2S)-2-fluorocyclopropyl] quinolone carboxylic acid compounds and preparation method thereof
CN103709100A (en) * 2013-12-31 2014-04-09 南京工业大学 Preparation method of 8-chloroquinolone derivative
CN104892600B (en) * 2015-06-04 2017-02-01 浙江司太立制药股份有限公司 7-(3-aminomethyl-4-substituted-benzyloxyimino-1-pyrrolidinyl)naphthyridinone carboxylic acid compounds
CN105061395A (en) * 2015-08-10 2015-11-18 江苏吴中医药集团有限公司 Preparation method for sitafloxacin hydrate
CN105669646B (en) * 2016-02-26 2018-03-09 济川药业集团有限公司 A kind of synthetic method of sitafloxacin
CN113527200B (en) * 2021-05-27 2022-12-02 北京斯利安药业有限公司 Preparation method of cloquinadol

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2840437A1 (en) * 1978-09-16 1980-04-03 Hoechst Ag 8-CHLORINE-5,6,7,8-TETRAHYDRO-2-CHINOLONE AND 8-CHROME-5,6,7,8-TETRAHYDRO-2-CHINOLONE, THEIR HYDROCHLORIDE OR. HYDROBROMIDE AND METHOD FOR THE PRODUCTION THEREOF
EP0191185B1 (en) * 1984-12-14 1990-03-07 Daiichi Seiyaku Co., Ltd. Quinoline-carboxylic acid derivatives
JPH0635457B2 (en) * 1985-06-28 1994-05-11 杏林製薬株式会社 Pyridonecarboxylic acid derivative and method for producing the same
DE3635218A1 (en) * 1986-10-16 1988-04-21 Bayer Ag 7-AMINO-1-CYCLOPROPYL-8-CHLORINE-6-FLUOR-1,4-DIHYDRO-4-OXO-3-CHINOLINE CARBONIC ACIDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR ANTIBACTERIAL AGENTS CONTAINING THEM
JPS6490183A (en) * 1987-09-30 1989-04-06 Kyorin Seiyaku Kk Production of quinolonecarboxylic acid derivative
JPH0196786A (en) * 1987-10-09 1989-04-14 Toshiba Corp Data totalization processing system for ticket checker
MY105136A (en) * 1988-04-27 1994-08-30 Daiichi Seiyaku Co Optically active pyridonecarboxylic acid derivatives.
CA1336090C (en) * 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives

Also Published As

Publication number Publication date
NO914053D0 (en) 1991-10-16
PL292087A1 (en) 1992-11-16
FI100531B (en) 1997-12-31
CN1038509C (en) 1998-05-27
NO914053L (en) 1992-04-21
GR910100427A (en) 1992-09-25
HU221195B1 (en) 2002-08-28
ES2039300A1 (en) 1993-09-16
PT99268A (en) 1992-08-31
YU165791A (en) 1994-05-10
EE03027B1 (en) 1997-08-15
PL168831B1 (en) 1996-04-30
YU48819B (en) 2001-12-26
ATA206691A (en) 1996-10-15
HUT59388A (en) 1992-05-28
AT402501B (en) 1997-06-25
RU2049778C1 (en) 1995-12-10
FI914875A0 (en) 1991-10-16
KR920008007A (en) 1992-05-27
FI914875A (en) 1992-04-19
ES2039300B1 (en) 1994-05-16
HU913280D0 (en) 1992-01-28
NO179517C (en) 1996-10-23
MX9101668A (en) 1992-06-05
PT99268B (en) 1999-04-30
CN1062906A (en) 1992-07-22
NO179517B (en) 1996-07-15
MY109714A (en) 1997-04-30
KR100253047B1 (en) 2000-05-01
GR1000997B (en) 1993-03-31

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