AR230056A1 - Procedimiento para la preparacion de derivados del acido 3-ridilmetilo 3-piridilmetilo 3-inidazolilmetil indolil-acrilico - Google Patents
Procedimiento para la preparacion de derivados del acido 3-ridilmetilo 3-piridilmetilo 3-inidazolilmetil indolil-acrilicoInfo
- Publication number
- AR230056A1 AR230056A1 AR289873A AR28987382A AR230056A1 AR 230056 A1 AR230056 A1 AR 230056A1 AR 289873 A AR289873 A AR 289873A AR 28987382 A AR28987382 A AR 28987382A AR 230056 A1 AR230056 A1 AR 230056A1
- Authority
- AR
- Argentina
- Prior art keywords
- ridilmetilo
- piridilmetilo
- inidazolilmetil
- acrilico
- indolil
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8120878 | 1981-07-07 | ||
| GB8213864 | 1982-05-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR230056A1 true AR230056A1 (es) | 1984-02-29 |
Family
ID=26280039
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR289873A AR230056A1 (es) | 1981-07-07 | 1982-07-02 | Procedimiento para la preparacion de derivados del acido 3-ridilmetilo 3-piridilmetilo 3-inidazolilmetil indolil-acrilico |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4451472A (es) |
| EP (1) | EP0069513B1 (es) |
| AR (1) | AR230056A1 (es) |
| AU (1) | AU532640B2 (es) |
| CS (1) | CS229934B2 (es) |
| DD (1) | DD202714A5 (es) |
| DE (1) | DE3275545D1 (es) |
| DK (1) | DK297382A (es) |
| ES (1) | ES513765A0 (es) |
| FI (1) | FI822386L (es) |
| GB (1) | GB2101992A (es) |
| GR (1) | GR76214B (es) |
| IL (1) | IL66223A0 (es) |
| NO (1) | NO822360L (es) |
| PL (1) | PL240814A1 (es) |
| PT (1) | PT75191B (es) |
| YU (1) | YU145482A (es) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4536505A (en) * | 1983-05-17 | 1985-08-20 | Ciba-Geigy Corporation | Certain N-(pyridyl) indoles |
| US4609733A (en) * | 1984-12-27 | 1986-09-02 | Ciba-Geigy Corporation | 3-keto-substituted-N-pyridylindoles |
| EP0427860A1 (en) * | 1989-03-31 | 1991-05-22 | Kyoto Pharmaceutical Industries, Ltd. | New imidazole derivatives, production thereof, and uses thereof as medicines |
| JPH03258779A (ja) * | 1990-03-06 | 1991-11-19 | Mitsui Toatsu Chem Inc | イミダゾール誘導体及び該イミダゾール誘導体を有効成分とする抗痙攣剤 |
| US5538973A (en) * | 1992-03-27 | 1996-07-23 | Kyoto Pharmaceutical Industries, Ltd. | Imidazole derivative, pharmaceutical use thereof, and intermediate therefor |
| GB9310635D0 (en) * | 1993-05-21 | 1993-07-07 | Glaxo Group Ltd | Chemical compounds |
| GB9319100D0 (en) * | 1993-09-15 | 1993-11-03 | Pfizer Ltd | 3-(3-pyridinyl)h-indoles |
| TWI574957B (zh) | 2011-07-29 | 2017-03-21 | 佳佑製藥治療公司 | 含有醯肼的核運輸調控子及其用途 |
| DK3404027T3 (da) | 2012-05-09 | 2020-06-02 | Biogen Ma Inc | Cellekernetransportmodulatorer og anvendelser deraf |
| WO2014144772A1 (en) | 2013-03-15 | 2014-09-18 | Karyopharm Therapeutics Inc. | Methods of promoting wound healing using crm1 inhibitors |
| ES2952774T3 (es) | 2013-06-21 | 2023-11-06 | Karyopharm Therapeutics Inc | 1,2,4-triazoles como moduladores del transporte nuclear y uso en el tratamiento de formas específicas de cáncer |
| JP6777626B2 (ja) | 2014-08-15 | 2020-10-28 | カリオファーム セラピューティクス，インコーポレイテッド | セリネクソールの多形体 |
| WO2017117529A1 (en) | 2015-12-31 | 2017-07-06 | Karyopharm Therapeutics Inc. | Nuclear transport modulators and uses thereof |
| MA43530A (fr) | 2015-12-31 | 2018-11-07 | Karyopharm Therapeutics Inc | Modulateurs de transport nucléaire et leurs utilisations |
| WO2018098472A1 (en) | 2016-11-28 | 2018-05-31 | Karyopharm Therapeutics Inc. | Crm1 inhibitors for treating epilepsy |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3445472A (en) * | 1965-12-03 | 1969-05-20 | American Home Prod | Mono- and di-aroyl pyridylethyl and piperidylethyl indoles |
| FR2272081A1 (en) * | 1974-05-22 | 1975-12-19 | Labaz | Anti-inflammatory indolylpyridylketones prepn. - from 2-alkyl (or aryl) indole and pyridine carboxylic acid chlorides |
| DE2960547D1 (en) * | 1978-02-24 | 1981-11-05 | Pfizer Ltd | 3-(imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them |
| IT1162310B (it) * | 1978-05-02 | 1987-03-25 | Ono Pharmaceutical Co | Derivati di imidazolo e procedimento per produrli |
| JPS55313A (en) * | 1978-06-13 | 1980-01-05 | Kissei Pharmaceut Co Ltd | Imidazole derivative |
| JPS5951943B2 (ja) * | 1978-08-21 | 1984-12-17 | キツセイ薬品工業株式会社 | 新規なイミダゾ−ル誘導体 |
| GB2045244B (en) * | 1979-03-07 | 1983-01-26 | Pfizer Ltd | 3-1-(imidazolylalkyl) indoles |
| US4363912A (en) * | 1980-12-15 | 1982-12-14 | Pfizer Inc. | Indole thromboxane synthetase inhibitors |
-
1982
- 1982-06-23 CS CS825037A patent/CS229934B2/cs unknown
- 1982-06-25 DE DE8282303313T patent/DE3275545D1/de not_active Expired
- 1982-06-25 GB GB08218431A patent/GB2101992A/en not_active Withdrawn
- 1982-06-25 EP EP82303313A patent/EP0069513B1/en not_active Expired
- 1982-07-01 PL PL24081482A patent/PL240814A1/xx unknown
- 1982-07-02 AR AR289873A patent/AR230056A1/es active
- 1982-07-02 DK DK297382A patent/DK297382A/da unknown
- 1982-07-02 US US06/394,554 patent/US4451472A/en not_active Expired - Fee Related
- 1982-07-05 GR GR68642A patent/GR76214B/el unknown
- 1982-07-05 FI FI822386A patent/FI822386L/fi not_active Application Discontinuation
- 1982-07-05 YU YU01454/82A patent/YU145482A/xx unknown
- 1982-07-05 IL IL66223A patent/IL66223A0/xx unknown
- 1982-07-06 DD DD82241446A patent/DD202714A5/de unknown
- 1982-07-06 ES ES513765A patent/ES513765A0/es active Granted
- 1982-07-06 NO NO822360A patent/NO822360L/no unknown
- 1982-07-06 AU AU85638/82A patent/AU532640B2/en not_active Ceased
- 1982-07-06 PT PT75191A patent/PT75191B/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES8305355A1 (es) | 1983-04-01 |
| EP0069513A2 (en) | 1983-01-12 |
| YU145482A (en) | 1985-03-20 |
| AU8563882A (en) | 1983-02-03 |
| CS229934B2 (en) | 1984-07-16 |
| US4451472A (en) | 1984-05-29 |
| GR76214B (es) | 1984-08-04 |
| PL240814A1 (en) | 1983-10-10 |
| PT75191B (en) | 1985-10-04 |
| NO822360L (no) | 1983-01-10 |
| AU532640B2 (en) | 1983-10-06 |
| DD202714A5 (de) | 1983-09-28 |
| FI822386A0 (fi) | 1982-07-05 |
| IL66223A0 (en) | 1982-11-30 |
| EP0069513A3 (en) | 1984-03-21 |
| EP0069513B1 (en) | 1987-03-04 |
| PT75191A (en) | 1982-08-01 |
| GB2101992A (en) | 1983-01-26 |
| FI822386L (fi) | 1983-01-08 |
| DE3275545D1 (en) | 1987-04-09 |
| DK297382A (da) | 1983-01-08 |
| ES513765A0 (es) | 1983-04-01 |
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