AR228256A1 - PROCEDURE FOR THE ELABORATION OF NEW COMPOUNDS OF 2- (PIRIMIDINILAMINO) -1,3-DIAZA-2-CICLOALQUENO - Google Patents
PROCEDURE FOR THE ELABORATION OF NEW COMPOUNDS OF 2- (PIRIMIDINILAMINO) -1,3-DIAZA-2-CICLOALQUENOInfo
- Publication number
- AR228256A1 AR228256A1 AR281109A AR28110980A AR228256A1 AR 228256 A1 AR228256 A1 AR 228256A1 AR 281109 A AR281109 A AR 281109A AR 28110980 A AR28110980 A AR 28110980A AR 228256 A1 AR228256 A1 AR 228256A1
- Authority
- AR
- Argentina
- Prior art keywords
- pirimidinilamino
- cicloalqueno
- diaza
- elaboration
- procedure
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH466979 | 1979-05-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR228256A1 true AR228256A1 (en) | 1983-02-15 |
Family
ID=4280399
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AR281109A AR228256A1 (en) | 1979-05-18 | 1980-05-19 | PROCEDURE FOR THE ELABORATION OF NEW COMPOUNDS OF 2- (PIRIMIDINILAMINO) -1,3-DIAZA-2-CICLOALQUENO |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0019811A1 (en) |
| JP (1) | JPS55154971A (en) |
| KR (1) | KR830002757A (en) |
| AR (1) | AR228256A1 (en) |
| AU (1) | AU5848480A (en) |
| DD (1) | DD150609A5 (en) |
| DK (1) | DK214480A (en) |
| ES (1) | ES8104279A1 (en) |
| FI (1) | FI801600A7 (en) |
| GB (1) | GB2052487B (en) |
| GR (1) | GR68453B (en) |
| IE (1) | IE49803B1 (en) |
| IL (1) | IL60086A (en) |
| MA (1) | MA18829A1 (en) |
| NO (1) | NO801469L (en) |
| NZ (1) | NZ193730A (en) |
| OA (1) | OA06533A (en) |
| PL (1) | PL224313A1 (en) |
| PT (1) | PT71251A (en) |
| ZA (1) | ZA802909B (en) |
| ZW (1) | ZW11880A1 (en) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4507146A (en) * | 1982-12-28 | 1985-03-26 | Ciba-Geigy Corporation | 2,4-Diamino-6-halo-5-trifluoromethylpyrimidines having herbicidal activity |
| DE3829469A1 (en) * | 1988-08-31 | 1990-03-01 | Bayer Ag | METHOD FOR THE PRODUCTION OF SUBSTITUTED N-AZINYL-N'-SULFONYL-ISOTHIO-UREAS AND N-AZINYL-IMINODITHIOCARBONIC ACID-S, S-DIESTER AS INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION |
| EP0954316A4 (en) * | 1997-09-03 | 2002-02-13 | Lilly Co Eli | Pyrimidine derivatives |
| JP2004509115A (en) | 2000-09-15 | 2004-03-25 | バーテックス ファーマシューティカルズ インコーポレイテッド | Pyrazole compounds useful as protein kinase inhibitors |
| US6660731B2 (en) | 2000-09-15 | 2003-12-09 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| US7473691B2 (en) | 2000-09-15 | 2009-01-06 | Vertex Pharmaceuticals Incorporated | Pyrazole compounds useful as protein kinase inhibitors |
| NZ526472A (en) | 2000-12-21 | 2004-04-30 | Vertex Pharma | Pyrazole compounds useful as protein kinase inhibitors |
| CZ20032341A3 (en) * | 2001-01-31 | 2004-12-15 | Synaptic Pharmaceutical Corporation | Use of GAL3 receptor antagonists for treating depression and/or anxiety |
| WO2003076414A2 (en) | 2002-03-13 | 2003-09-18 | Euro-Celtique S.A. | Aryl substituted pyrimidines and the use thereof |
| JP2005520821A (en) * | 2002-03-15 | 2005-07-14 | チバ スペシャルティ ケミカルズ ホールディング インコーポレーテッド | 4-Aminopyrimidine and its use for antimicrobial treatment of surfaces |
| US20040009981A1 (en) | 2002-03-15 | 2004-01-15 | David Bebbington | Compositions useful as inhibitors of protein kinases |
| MY141867A (en) | 2002-06-20 | 2010-07-16 | Vertex Pharma | Substituted pyrimidines useful as protein kinase inhibitors |
| PL374967A1 (en) | 2002-08-02 | 2005-11-14 | Vertex Pharmaceuticals Incorporated | Pyrazole compositions useful as inhibitors of gsk-3 |
| US7601718B2 (en) | 2003-02-06 | 2009-10-13 | Vertex Pharmaceuticals Incorporated | Compositions useful as inhibitors of protein kinases |
| EP1917259B1 (en) | 2005-08-18 | 2012-01-25 | Vertex Pharmaceuticals Incorporated | Pyrazine kinase inhibitors |
| AU2006311797A1 (en) | 2005-11-03 | 2007-05-18 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines useful as kinase inhibitors |
| NZ576750A (en) | 2006-11-02 | 2012-01-12 | Vertex Pharma | Aminopyridines and aminopyrimidines useful as inhibitors of protein kinases |
| WO2008077086A1 (en) | 2006-12-19 | 2008-06-26 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines useful as inhibitors of protein kinases |
| EP2134709A1 (en) | 2007-03-09 | 2009-12-23 | Vertex Pharmaceuticals, Inc. | Aminopyridines useful as inhibitors of protein kinases |
| ATE526328T1 (en) | 2007-03-09 | 2011-10-15 | Vertex Pharma | AMINOPYRIMIDINES SUITABLE AS INHIBITORS OF PROTEIN KINASES |
| WO2008112642A1 (en) | 2007-03-09 | 2008-09-18 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines useful as inhibitors of protein kinases |
| MX2009011059A (en) | 2007-04-13 | 2009-11-26 | Vertex Pharma | Aminopyrimidines useful as kinase inhibitors. |
| AU2008247594A1 (en) | 2007-05-02 | 2008-11-13 | Vertex Pharmaceuticals Incorporated | Aminopyrimidines useful as kinase inhibitors |
| JP5389785B2 (en) | 2007-05-02 | 2014-01-15 | バーテックス ファーマシューティカルズ インコーポレイテッド | Thiazoles and pyrazoles useful as kinase inhibitors |
| EP2176261B1 (en) | 2007-07-31 | 2012-12-19 | Vertex Pharmaceuticals Incorporated | Process for preparing 5-fluoro-1h-pyrazolo [3, 4-b] pyridin-3-amine and derivatives thereof |
| KR20110050549A (en) | 2008-09-03 | 2011-05-13 | 버텍스 파마슈티칼스 인코포레이티드 | Co-crystals and pharmaceutical formulations comprising the same |
| CN103497192B (en) * | 2008-12-09 | 2015-09-23 | 吉里德科学公司 | Toll-like receptor conditioning agent |
| KR102328682B1 (en) | 2018-08-27 | 2021-11-18 | 주식회사 대웅제약 | Novel heterocyclicamine derivatives and pharmaceutical composition comprising the same |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE754832A (en) * | 1969-08-14 | 1971-02-15 | Beecham Group Ltd | IMINAZOLINES |
-
1980
- 1980-05-05 MA MA19025A patent/MA18829A1/en unknown
- 1980-05-13 DD DD80221082A patent/DD150609A5/en unknown
- 1980-05-14 ES ES491514A patent/ES8104279A1/en not_active Expired
- 1980-05-15 NZ NZ193730A patent/NZ193730A/en unknown
- 1980-05-15 IL IL60086A patent/IL60086A/en unknown
- 1980-05-16 ZW ZW118/80A patent/ZW11880A1/en unknown
- 1980-05-16 NO NO801469A patent/NO801469L/en unknown
- 1980-05-16 FI FI801600A patent/FI801600A7/en not_active Application Discontinuation
- 1980-05-16 PT PT71251A patent/PT71251A/en unknown
- 1980-05-16 AU AU58484/80A patent/AU5848480A/en not_active Abandoned
- 1980-05-16 ZA ZA00802909A patent/ZA802909B/en unknown
- 1980-05-16 IE IE1023/80A patent/IE49803B1/en unknown
- 1980-05-16 GB GB8016309A patent/GB2052487B/en not_active Expired
- 1980-05-16 EP EP80102724A patent/EP0019811A1/en not_active Withdrawn
- 1980-05-16 GR GR61963A patent/GR68453B/el unknown
- 1980-05-16 DK DK214480A patent/DK214480A/en not_active Application Discontinuation
- 1980-05-17 JP JP6586380A patent/JPS55154971A/en active Pending
- 1980-05-17 KR KR1019800001944A patent/KR830002757A/en active Pending
- 1980-05-17 OA OA57113A patent/OA06533A/en unknown
- 1980-05-17 PL PL22431380A patent/PL224313A1/xx unknown
- 1980-05-19 AR AR281109A patent/AR228256A1/en active
Also Published As
| Publication number | Publication date |
|---|---|
| DD150609A5 (en) | 1981-09-09 |
| FI801600A7 (en) | 1980-11-19 |
| EP0019811A1 (en) | 1980-12-10 |
| ZA802909B (en) | 1981-05-27 |
| JPS55154971A (en) | 1980-12-02 |
| IE801023L (en) | 1980-11-18 |
| IE49803B1 (en) | 1985-12-25 |
| DK214480A (en) | 1980-11-19 |
| AU5848480A (en) | 1980-11-20 |
| NZ193730A (en) | 1982-12-21 |
| IL60086A (en) | 1984-03-30 |
| ZW11880A1 (en) | 1980-12-17 |
| MA18829A1 (en) | 1980-12-31 |
| ES491514A0 (en) | 1981-04-16 |
| ES8104279A1 (en) | 1981-04-16 |
| IL60086A0 (en) | 1980-07-31 |
| NO801469L (en) | 1980-11-19 |
| OA06533A (en) | 1981-07-31 |
| KR830002757A (en) | 1983-05-30 |
| GB2052487A (en) | 1981-01-28 |
| PT71251A (en) | 1980-06-01 |
| GB2052487B (en) | 1983-05-11 |
| GR68453B (en) | 1981-12-30 |
| PL224313A1 (en) | 1981-02-13 |
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