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AR225274A1 - PROCEDURE FOR PREPARING DERIVATIVES OF 1- (2- (3-INDOLIL) -1,1-DIMETHYL) -AMINO) 3-PHENOXY OR 3-NAFTILOXI-2-PROPANOL AND ITS ADDITIONAL SALTS OF ACIDS - Google Patents

PROCEDURE FOR PREPARING DERIVATIVES OF 1- (2- (3-INDOLIL) -1,1-DIMETHYL) -AMINO) 3-PHENOXY OR 3-NAFTILOXI-2-PROPANOL AND ITS ADDITIONAL SALTS OF ACIDS

Info

Publication number
AR225274A1
AR225274A1 AR272873A AR27287378A AR225274A1 AR 225274 A1 AR225274 A1 AR 225274A1 AR 272873 A AR272873 A AR 272873A AR 27287378 A AR27287378 A AR 27287378A AR 225274 A1 AR225274 A1 AR 225274A1
Authority
AR
Argentina
Prior art keywords
naftiloxi
indolil
phenoxy
propanol
dimethyl
Prior art date
Application number
AR272873A
Other languages
Spanish (es)
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Application granted granted Critical
Publication of AR225274A1 publication Critical patent/AR225274A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AR272873A 1977-07-13 1978-07-07 PROCEDURE FOR PREPARING DERIVATIVES OF 1- (2- (3-INDOLIL) -1,1-DIMETHYL) -AMINO) 3-PHENOXY OR 3-NAFTILOXI-2-PROPANOL AND ITS ADDITIONAL SALTS OF ACIDS AR225274A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81513877A 1977-07-13 1977-07-13

Publications (1)

Publication Number Publication Date
AR225274A1 true AR225274A1 (en) 1982-03-15

Family

ID=25216976

Family Applications (1)

Application Number Title Priority Date Filing Date
AR272873A AR225274A1 (en) 1977-07-13 1978-07-07 PROCEDURE FOR PREPARING DERIVATIVES OF 1- (2- (3-INDOLIL) -1,1-DIMETHYL) -AMINO) 3-PHENOXY OR 3-NAFTILOXI-2-PROPANOL AND ITS ADDITIONAL SALTS OF ACIDS

Country Status (30)

Country Link
JP (1) JPS5419972A (en)
AR (1) AR225274A1 (en)
AT (1) AT364821B (en)
AU (1) AU525064B2 (en)
BE (1) BE868943A (en)
CA (1) CA1116598A (en)
CH (1) CH642066A5 (en)
CY (1) CY1274A (en)
DE (1) DE2830884A1 (en)
DK (1) DK156568C (en)
ES (1) ES471674A1 (en)
FI (1) FI69835C (en)
FR (1) FR2397404A1 (en)
GB (1) GB2001633B (en)
GR (1) GR74488B (en)
HK (1) HK1385A (en)
HU (1) HU178992B (en)
IE (1) IE47122B1 (en)
IL (1) IL55115A (en)
IT (1) IT1105091B (en)
KE (1) KE3485A (en)
LU (1) LU79966A1 (en)
MY (1) MY8500946A (en)
NL (1) NL189946C (en)
NO (1) NO149311C (en)
NZ (1) NZ187763A (en)
SE (1) SE429339B (en)
SG (1) SG82584G (en)
YU (1) YU40528B (en)
ZA (1) ZA783744B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2463765A1 (en) * 1979-08-17 1981-02-27 Clin Midy NEW ACTIVE INDOLE DERIVATIVES ON THE CARDIOVASCULAR SYSTEM
US4321398A (en) * 1981-05-07 1982-03-23 Mead Johnson & Company Thienyl and benzothienyl-tertiary butylaminophenoxypropanols
DE3119796A1 (en) * 1981-05-19 1982-12-23 Hoechst Ag, 6000 Frankfurt SUBSTITUTED TRYPTAMINE DERIVATIVES OF THIENYLOX PROPANOLAMINES, METHODS FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS BASED ON THESE COMPOUNDS AND THEIR USE
FR2523964B1 (en) * 1982-03-23 1985-09-27 Sanofi Sa NOVEL TRYPTAMINE DERIVATIVES ACTIVE IN PARTICULAR ON THE CARDIOVASCULAR SYSTEM AND PROCESS FOR THEIR PREPARATION
NZ208337A (en) * 1983-06-10 1988-10-28 Bristol Myers Co 2-(2-hydroxy-3-((2-(ar-hydroxy-1h-aminopropoxy-yl)ethyl benzonitriles and pharmaceutical compositions
FR2601008B1 (en) * 1986-07-03 1990-03-30 Sanofi Sa PROCESS FOR THE STEREOSPECIFIC SYNTHESIS OF INDOLE DERIVATIVES
CA2421594A1 (en) 2000-11-10 2002-05-16 John Arnold Werner 3-substituted oxindole beta 3 agonists
US6911463B2 (en) 2001-08-14 2005-06-28 Eli Lilly And Company 3-substituted oxindole β-3 agonists
DE60215028T2 (en) 2001-08-14 2007-03-15 Eli Lilly And Co., Indianapolis INDOL DERIVATIVES AS BETA-3-ADRENERGE AGONISTS FOR THE TREATMENT OF TYPE 2 DIABETES
JP2005518357A (en) 2001-11-20 2005-06-23 イーライ・リリー・アンド・カンパニー Beta 3 adrenergic agonist
JP2005514366A (en) 2001-11-20 2005-05-19 イーライ・リリー・アンド・カンパニー 3-Substituted oxindole β3 agonist
EP1467733A1 (en) 2002-01-11 2004-10-20 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as beta3 agonists
US8946284B2 (en) 2008-08-01 2015-02-03 Arca Biopharma, Inc. Methods and compositions involving (S)-bucindolol

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1532210A (en) * 1963-06-21 1968-07-12 Ici Ltd Heterocyclic compounds and their preparation process
CH495983A (en) * 1968-02-09 1970-09-15 Sandoz Ag Process for the preparation of levorotatory 4- (2-hydroxy-3-isopropylaminopropoxy) indole
US3371098A (en) * 1966-11-29 1968-02-27 Philips Corp 5- and 6-methoxy-3-(phenoxyethyl-aminoethyl)-indoles
US3946009A (en) * 1972-05-05 1976-03-23 Merck Sharp & Dohme (I.A.) Corporation 2-(3-Substituted amino-2-hydroxypropoxy)-3-substituted pyrazines

Also Published As

Publication number Publication date
AU3770478A (en) 1980-01-10
NL7807564A (en) 1979-01-16
DK156568B (en) 1989-09-11
NO149311B (en) 1983-12-19
NO782407L (en) 1979-01-16
GB2001633B (en) 1982-03-24
FI782205A (en) 1979-01-14
JPS5419972A (en) 1979-02-15
FR2397404A1 (en) 1979-02-09
GB2001633A (en) 1979-02-07
IE47122B1 (en) 1983-12-28
NZ187763A (en) 1984-07-31
FR2397404B1 (en) 1982-06-11
ES471674A1 (en) 1979-10-01
IT7850228A0 (en) 1978-07-10
AT364821B (en) 1981-11-25
JPS6340784B2 (en) 1988-08-12
LU79966A1 (en) 1979-04-09
CY1274A (en) 1985-03-08
MY8500946A (en) 1985-12-31
IT1105091B (en) 1985-10-28
CA1116598A (en) 1982-01-19
YU40528B (en) 1986-02-28
KE3485A (en) 1985-01-25
YU161178A (en) 1983-02-28
HK1385A (en) 1985-01-11
FI69835C (en) 1986-05-26
ATA508978A (en) 1981-04-15
DK313878A (en) 1979-01-14
GR74488B (en) 1984-06-28
HU178992B (en) 1982-07-28
NL189946B (en) 1993-04-16
SG82584G (en) 1985-09-13
IL55115A0 (en) 1978-09-29
SE429339B (en) 1983-08-29
DK156568C (en) 1990-02-05
DE2830884C2 (en) 1990-01-11
ZA783744B (en) 1979-07-25
AU525064B2 (en) 1982-10-21
CH642066A5 (en) 1984-03-30
IL55115A (en) 1981-09-13
DE2830884A1 (en) 1979-02-01
FI69835B (en) 1985-12-31
BE868943A (en) 1979-01-12
NL189946C (en) 1993-09-16
IE781400L (en) 1979-01-13
SE7807700L (en) 1979-01-14
NO149311C (en) 1984-03-28

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