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AR224786A1 - Un procedimiento para preparar un derivado enzimico - Google Patents

Un procedimiento para preparar un derivado enzimico

Info

Publication number
AR224786A1
AR224786A1 AR283122A AR28312280A AR224786A1 AR 224786 A1 AR224786 A1 AR 224786A1 AR 283122 A AR283122 A AR 283122A AR 28312280 A AR28312280 A AR 28312280A AR 224786 A1 AR224786 A1 AR 224786A1
Authority
AR
Argentina
Prior art keywords
preparing
procedure
enzyme derivative
enzyme
derivative
Prior art date
Application number
AR283122A
Other languages
English (en)
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Application granted granted Critical
Publication of AR224786A1 publication Critical patent/AR224786A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3153Streptokinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99Enzyme inactivation by chemical treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AR283122A 1979-11-05 1980-11-04 Un procedimiento para preparar un derivado enzimico AR224786A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7938279 1979-11-05

Publications (1)

Publication Number Publication Date
AR224786A1 true AR224786A1 (es) 1982-01-15

Family

ID=10508982

Family Applications (1)

Application Number Title Priority Date Filing Date
AR283122A AR224786A1 (es) 1979-11-05 1980-11-04 Un procedimiento para preparar un derivado enzimico

Country Status (18)

Country Link
US (1) US4808405A (es)
EP (1) EP0028489B1 (es)
JP (1) JPS5678590A (es)
AR (1) AR224786A1 (es)
CA (1) CA1174621A (es)
CS (2) CS391991A3 (es)
DE (1) DE3065190D1 (es)
DK (1) DK158994C (es)
ES (1) ES496586A0 (es)
GR (1) GR72121B (es)
HK (1) HK65886A (es)
HU (1) HU185223B (es)
IE (1) IE50174B1 (es)
IL (1) IL61408A (es)
NL (1) NL930029I2 (es)
NO (1) NO163867C (es)
NZ (1) NZ195469A (es)
ZA (1) ZA806641B (es)

Families Citing this family (78)

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EP0125269A1 (en) * 1982-11-11 1984-11-21 Beecham Group Plc Pharmaceutically active compounds
GB8400653D0 (en) * 1984-01-11 1984-02-15 Beecham Group Plc Conjugates
GB8430253D0 (en) * 1984-11-30 1985-01-09 Beecham Group Plc Compounds
US5231006A (en) * 1986-10-16 1993-07-27 Behringwerke Aktiengesellschaft Method for the determination of plasminogen
US5256642A (en) * 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
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AU647391B2 (en) * 1989-05-01 1994-03-24 University Of Notre Dame Du Lac, The Methods and materials for expression of human plasminogen in a eukaryotic cell system
EP0397366A1 (en) * 1989-05-09 1990-11-14 The Board Of Regents Of The University Of Oklahoma Hybrid streptokinases with fibrin binding domains and methods for the synthesis of same
ATE135200T1 (de) * 1989-05-17 1996-03-15 Res Corp Technologies Inc Verfahren und zusammensetzung zur thrombosebehandlung beim säugetier
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US5087572A (en) * 1989-12-01 1992-02-11 Genentech, Inc. Dna encoding human plasminogen modified at the cleavage site
US5190756A (en) * 1989-12-01 1993-03-02 Genentech, Inc. Methods and materials for expression of human plasminogen variant
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US6458360B1 (en) 1990-04-25 2002-10-01 The Johns Hopkins University Soluble complement regulatory molecules
US5187069A (en) * 1990-08-06 1993-02-16 Henry Ford Health System Active site labelling of plasminogen
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US5520912A (en) * 1993-07-02 1996-05-28 Immuno Aktiengesellschaft Prevention and treatment of ischemic events and reperfusion injury resulting therefrom using lys-plasminogen
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US8222453B2 (en) 2006-06-08 2012-07-17 Bristol-Myers Squibb Company Benzamide factor VIIa inhibitors useful as anticoagulants
US7960569B2 (en) 2006-10-17 2011-06-14 Bristol-Myers Squibb Company Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
US7910597B2 (en) * 2006-11-28 2011-03-22 Shire Llc Substituted quinazolines
US8304420B2 (en) 2006-11-28 2012-11-06 Shire Llc Substituted quinazolines for reducing platelet count
JP5342450B2 (ja) 2006-12-15 2013-11-13 ブリストル−マイヤーズ スクイブ カンパニー 第XIa因子インヒビターとしてのアリールプロピオンアミド、アリールアクリルアミド、アリールプロピンアミド、またはアリールメチルウレアアナログ
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US8367709B2 (en) 2007-06-13 2013-02-05 Bristol-Myers Squibb Company Dipeptide analogs as coagulation factor inhibitors
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WO2015116885A1 (en) 2014-01-31 2015-08-06 Bristol-Myers Squibb Company Macrocycles with aromatic p2' groups as factor xia inhibitors
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HUE057876T2 (hu) 2014-04-04 2022-06-28 Pfizer Biciklusos-kondenzált heteroaril- vagy aril-vegyületek és ezek IRAK4 inhibitorként történõ alkalmazása
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US4178368A (en) * 1971-09-30 1979-12-11 Behringwerke Aktiengesellschaft Method for the treatment of thromboembolism
JPS5325775A (en) * 1976-08-24 1978-03-09 Miller Fluid Power Corp Module type fluid flow control element
US4082612A (en) * 1976-09-24 1978-04-04 Michael Reese Research Foundation Plasminogen activator complex
NZ191320A (en) * 1978-09-07 1982-09-14 Beecham Group Ltd In vivo fibrinolytic enzyme having active site blocked by hydrolytically removable group pharmaceutical compositions

Also Published As

Publication number Publication date
EP0028489B1 (en) 1983-10-05
JPS5678590A (en) 1981-06-27
HU185223B (en) 1984-12-28
JPH0316114B2 (es) 1991-03-04
NO163867C (no) 1990-08-01
NL930029I2 (nl) 1993-12-01
IL61408A0 (en) 1980-12-31
NO803304L (no) 1981-05-06
IE802277L (en) 1981-05-05
US4808405A (en) 1989-02-28
ES8204467A1 (es) 1982-05-01
AU534017B2 (en) 1983-12-22
AU6401180A (en) 1981-05-14
IL61408A (en) 1983-10-31
NO163867B (no) 1990-04-23
ZA806641B (en) 1981-10-28
CA1174621A (en) 1984-09-18
EP0028489A1 (en) 1981-05-13
DK468880A (da) 1981-05-06
IE50174B1 (en) 1986-02-19
NL930029I1 (nl) 1993-06-01
GR72121B (es) 1983-09-16
CS391991A3 (en) 1992-06-17
DK158994B (da) 1990-08-13
CS391191A3 (en) 1992-08-12
DK158994C (da) 1991-01-07
NZ195469A (en) 1984-05-31
ES496586A0 (es) 1982-05-01
DE3065190D1 (en) 1983-11-10
HK65886A (en) 1986-09-12

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