AR115269A1 - Cápsulas de gelatina blanda entéricas - Google Patents
Cápsulas de gelatina blanda entéricasInfo
- Publication number
- AR115269A1 AR115269A1 ARP190100661A ARP190100661A AR115269A1 AR 115269 A1 AR115269 A1 AR 115269A1 AR P190100661 A ARP190100661 A AR P190100661A AR P190100661 A ARP190100661 A AR P190100661A AR 115269 A1 AR115269 A1 AR 115269A1
- Authority
- AR
- Argentina
- Prior art keywords
- enteric
- weight
- soft gelatin
- enteric soft
- gelatin capsule
- Prior art date
Links
- 229920000159 gelatin Polymers 0.000 title abstract 7
- 235000019322 gelatine Nutrition 0.000 title abstract 7
- 239000002775 capsule Substances 0.000 title abstract 2
- 239000001828 Gelatine Substances 0.000 title 1
- 239000007903 gelatin capsule Substances 0.000 abstract 8
- 239000000203 mixture Substances 0.000 abstract 8
- 108010010803 Gelatin Proteins 0.000 abstract 6
- 239000008273 gelatin Substances 0.000 abstract 6
- 235000011852 gelatine desserts Nutrition 0.000 abstract 6
- 239000000463 material Substances 0.000 abstract 5
- 239000002702 enteric coating Substances 0.000 abstract 4
- 238000009505 enteric coating Methods 0.000 abstract 4
- PYMYPHUHKUWMLA-UHFFFAOYSA-N 2,3,4,5-tetrahydroxypentanal Chemical compound OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 abstract 3
- PEDCQBHIVMGVHV-UHFFFAOYSA-N glycerol group Chemical group OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 abstract 3
- 239000001814 pectin Substances 0.000 abstract 3
- 235000010987 pectin Nutrition 0.000 abstract 3
- 229920001277 pectin Polymers 0.000 abstract 3
- 239000004014 plasticizer Substances 0.000 abstract 3
- 239000001913 cellulose Substances 0.000 abstract 2
- 229920002678 cellulose Polymers 0.000 abstract 2
- 239000000945 filler Substances 0.000 abstract 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical group OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4833—Encapsulating processes; Filling of capsules
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Las cápsulas de gelatina blanda entéricas comprenden un material de relleno y una composición de cubierta entérica, caracterizadas porque la naturaleza entérica de las cápsulas puede alcanzarse sin un recubrimiento entérico ni polímeros entéricos convencionales agregados. Reivindicación 1: Una cápsula de gelatina blanda entérica, caracterizada porque comprende: (a) un material de relleno; y (b) una composición de cubierta, en donde el material de relleno comprende al menos un ingrediente farmacéuticamente activo, y en donde la composición de cubierta comprende de aproximadamente 40% en peso a aproximadamente 80% en peso de una gelatina, de aproximadamente 2,0% en peso a aproximadamente 20% en peso de una pectina con bajo metoxi, de aproximadamente 0,15% en peso a aproximadamente 4,0% en peso de un derivado de celulosa, y de aproximadamente 15% en peso a aproximadamente 40% en peso de un plastificante. Reivindicación 2: La cápsula de gelatina blanda entérica de la reivindicación, caracterizada porque la gelatina se selecciona entre el grupo que consiste en gelatina de Tipo A, gelatina de Tipo B, y mezclas de las mismas. Reivindicación 4: La cápsula de gelatina blanda entérica de una cualquiera de las reivindicaciones 1 - 3, caracterizada porque la pectina con bajo metoxi se selecciona entre el grupo que consiste en pectina LM (P-25), pectina LM (445C), pectina LM (100C) y combinaciones de las mismas. Reivindicación 6: La cápsula de gelatina blanda entérica de la reivindicación 5, caracterizada porque el plastificante es glicerol. Reivindicación 8: La cápsula de gelatina blanda entérica de la reivindicación 7, caracterizada porque el derivado de celulosa es hidroxipropilmetilcelulosa. Reivindicación 9: La cápsula de gelatina blanda entérica de una cualquiera de las reivindicaciones 1 - 8, caracterizada porque la composición de cubierta comprende de aproximadamente 45% en peso a aproximadamente 75% en peso de la gelatina. Reivindicación 19: Un proceso para preparar una cápsula de gelatina blanda entérica de acuerdo con una cualquiera de las reivindicaciones 1 - 18, caracterizado porque comprende los pasos de: (a) preparar el material de relleno; y (b) encapsular el material de relleno con una composición de cubierta entérica. Reivindicación 20: El proceso de acuerdo con la reivindicación 19, caracterizado porque además comprende preparar la composición de cubierta entérica mezclando una gelatina, HPMC, una pectina con bajo metoxi y un plastificante, en donde la composición de cubierta entérica está libre de polímeros entéricos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862643521P | 2018-03-15 | 2018-03-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR115269A1 true AR115269A1 (es) | 2020-12-16 |
Family
ID=67907228
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP190100661A AR115269A1 (es) | 2018-03-15 | 2019-03-15 | Cápsulas de gelatina blanda entéricas |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11980691B2 (es) |
| EP (1) | EP3768094B1 (es) |
| JP (1) | JP7303221B2 (es) |
| CN (1) | CN111867399B (es) |
| AR (1) | AR115269A1 (es) |
| AU (1) | AU2019236217A1 (es) |
| BR (1) | BR112020018277A2 (es) |
| CA (1) | CA3091686A1 (es) |
| IL (1) | IL276942B2 (es) |
| MX (1) | MX2020008650A (es) |
| PH (1) | PH12020500621A1 (es) |
| SG (1) | SG11202008715WA (es) |
| WO (1) | WO2019178444A1 (es) |
| ZA (1) | ZA202005153B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220400724A1 (en) * | 2019-10-28 | 2022-12-22 | R.P. Scherer Technologies, Llc | Delayed release softgel capsules in higher ph environment |
| CA3197516A1 (en) * | 2020-11-11 | 2022-05-19 | Karunakar Sukuru | Delayed release softgel capsules |
| CA3119012C (en) * | 2021-05-18 | 2023-10-17 | Gelentroceutics Inc. | Formulation of intrinsically acid-resistant vegetarian-based and gelatin-based soft gel capsules for pharmaceutical/nutraceutical products |
| CN118510499A (zh) * | 2022-02-03 | 2024-08-16 | 雀巢产品有限公司 | 具有耐胃酸胶囊外壳的口服剂型 |
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-
2019
- 2019-03-15 SG SG11202008715WA patent/SG11202008715WA/en unknown
- 2019-03-15 IL IL276942A patent/IL276942B2/en unknown
- 2019-03-15 BR BR112020018277-0A patent/BR112020018277A2/pt active Search and Examination
- 2019-03-15 MX MX2020008650A patent/MX2020008650A/es unknown
- 2019-03-15 JP JP2020573083A patent/JP7303221B2/ja active Active
- 2019-03-15 CN CN201980019102.9A patent/CN111867399B/zh active Active
- 2019-03-15 WO PCT/US2019/022411 patent/WO2019178444A1/en active Application Filing
- 2019-03-15 CA CA3091686A patent/CA3091686A1/en active Pending
- 2019-03-15 AU AU2019236217A patent/AU2019236217A1/en active Pending
- 2019-03-15 AR ARP190100661A patent/AR115269A1/es unknown
- 2019-03-15 US US16/979,485 patent/US11980691B2/en active Active
- 2019-03-15 EP EP19768554.8A patent/EP3768094B1/en active Active
-
2020
- 2020-08-19 PH PH12020500621A patent/PH12020500621A1/en unknown
- 2020-08-19 ZA ZA2020/05153A patent/ZA202005153B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL276942B1 (en) | 2024-07-01 |
| EP3768094A4 (en) | 2022-03-02 |
| ZA202005153B (en) | 2023-12-20 |
| EP3768094A1 (en) | 2021-01-27 |
| CA3091686A1 (en) | 2019-09-19 |
| PH12020500621A1 (en) | 2021-03-15 |
| CN111867399A (zh) | 2020-10-30 |
| IL276942B2 (en) | 2024-11-01 |
| WO2019178444A1 (en) | 2019-09-19 |
| MX2020008650A (es) | 2020-10-15 |
| RU2020132992A (ru) | 2022-04-15 |
| CN111867399B (zh) | 2024-10-29 |
| BR112020018277A2 (pt) | 2020-12-29 |
| EP3768094B1 (en) | 2024-05-01 |
| SG11202008715WA (en) | 2020-10-29 |
| IL276942A (en) | 2020-10-29 |
| US20210038526A1 (en) | 2021-02-11 |
| US11980691B2 (en) | 2024-05-14 |
| AU2019236217A1 (en) | 2020-09-17 |
| EP3768094C0 (en) | 2024-05-01 |
| JP7303221B2 (ja) | 2023-07-04 |
| JP2021518429A (ja) | 2021-08-02 |
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