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AR100157A1 - Composiciones y métodos para mejorar y/o predecir la amplificación de adn - Google Patents

Composiciones y métodos para mejorar y/o predecir la amplificación de adn

Info

Publication number
AR100157A1
AR100157A1 ARP150101211A ARP150101211A AR100157A1 AR 100157 A1 AR100157 A1 AR 100157A1 AR P150101211 A ARP150101211 A AR P150101211A AR P150101211 A ARP150101211 A AR P150101211A AR 100157 A1 AR100157 A1 AR 100157A1
Authority
AR
Argentina
Prior art keywords
region
white
compositions
oligonucleotide
methods
Prior art date
Application number
ARP150101211A
Other languages
English (en)
Original Assignee
Envirologix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54333131&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR100157(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Envirologix Inc filed Critical Envirologix Inc
Publication of AR100157A1 publication Critical patent/AR100157A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Composiciones y métodos para amplificar un oligonucleótido blanco en una muestra, que incluye la detección del oligonucleótido blanco en tiempo real. Reivindicación 1: Un oligonucleótido cebador aislado que comprende en la dirección 5 a 3, i) una primera región que comprende una secuencia autocomplementaria que comprende, en la dirección 5 a 3, el complemento inverso de una secuencia de reconocimiento de una enzima de mellado, una secuencia palindrómica y dicha secuencia de reconocimiento de una enzima de mellado, y ii) una segunda región de por lo menos 16 nucleótidos de longitud que se une específicamente a una región complementaria en una molécula de ácido nucleico blanco para formar un híbrido de cadena doble que tiene un DG que es por lo menos 15 kcal/mol menor que el DG de cualquier estructura alternativa que comprende la segunda región, en donde la segunda región comprende por el extremo 3 uno o más nucleótidos modificados en 2.
ARP150101211A 2014-04-22 2015-04-22 Composiciones y métodos para mejorar y/o predecir la amplificación de adn AR100157A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461982784P 2014-04-22 2014-04-22

Publications (1)

Publication Number Publication Date
AR100157A1 true AR100157A1 (es) 2016-09-14

Family

ID=54333131

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP150101211A AR100157A1 (es) 2014-04-22 2015-04-22 Composiciones y métodos para mejorar y/o predecir la amplificación de adn

Country Status (11)

Country Link
US (2) US11505836B2 (es)
EP (2) EP3748011B1 (es)
JP (1) JP6596442B2 (es)
CN (1) CN106460071B (es)
AR (1) AR100157A1 (es)
AU (2) AU2015249739B2 (es)
CA (1) CA2946737A1 (es)
MX (1) MX2016013877A (es)
RU (1) RU2723079C2 (es)
UA (1) UA123387C2 (es)
WO (1) WO2015164494A1 (es)

Families Citing this family (5)

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GB201715465D0 (en) * 2017-09-25 2017-11-08 Dnae Diagnostics Ltd Reversible Thermodynamic Trap (Thermo Trap) in Amplification of Nucleic Acids
CN109321669B (zh) * 2018-10-29 2022-03-15 江南大学 一种基于嵌合体序列设计和分子信标的荧光检测金黄色葡萄球菌的方法
CN116355989B (zh) * 2023-03-31 2024-03-08 深圳会众生物技术有限公司 一种核苷酸组合物、包含其的试剂盒及其应用

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Also Published As

Publication number Publication date
CN106460071B (zh) 2021-09-10
AU2015249739B2 (en) 2021-08-05
AU2021205135B2 (en) 2023-06-01
RU2723079C2 (ru) 2020-06-08
EP3134551A1 (en) 2017-03-01
EP3748011A1 (en) 2020-12-09
US20170044628A1 (en) 2017-02-16
US20230220495A1 (en) 2023-07-13
CA2946737A1 (en) 2015-10-29
US11505836B2 (en) 2022-11-22
JP2017513495A (ja) 2017-06-01
BR112016024622A2 (pt) 2017-10-10
AU2021205135A1 (en) 2021-08-12
JP6596442B2 (ja) 2019-10-23
WO2015164494A1 (en) 2015-10-29
RU2016145402A3 (es) 2019-04-17
EP3134551B1 (en) 2020-06-03
RU2016145402A (ru) 2018-05-23
UA123387C2 (uk) 2021-03-31
CN106460071A (zh) 2017-02-22
AU2015249739A1 (en) 2016-12-01
EP3134551A4 (en) 2017-12-06
EP3748011B1 (en) 2024-11-13
MX2016013877A (es) 2017-03-09

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