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AR093115A1 - Soluciones midriaticas y antiinflamatorias inyectables, estables y libres de conservantes - Google Patents

Soluciones midriaticas y antiinflamatorias inyectables, estables y libres de conservantes

Info

Publication number
AR093115A1
AR093115A1 ARP130103855A ARP130103855A AR093115A1 AR 093115 A1 AR093115 A1 AR 093115A1 AR P130103855 A ARP130103855 A AR P130103855A AR P130103855 A ARP130103855 A AR P130103855A AR 093115 A1 AR093115 A1 AR 093115A1
Authority
AR
Argentina
Prior art keywords
free
stable
midriatic
conservant
injectable
Prior art date
Application number
ARP130103855A
Other languages
English (en)
Inventor
Shen Hui
A Rong - Demopulos Gregory
E Tedford Clark
Original Assignee
Omeros Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50545210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR093115(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Omeros Corp filed Critical Omeros Corp
Publication of AR093115A1 publication Critical patent/AR093115A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/04—Artificial tears; Irrigation solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/08—Mydriatics or cycloplegics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Reivindicación 1: Una formulación farmacéutica líquida y estéril caracterizada porque comprende fenilefrina, ketorolac y un sistema amortiguador en un vehículo acuoso, donde la formulación se encuentra libre de conservantes y libre de antioxidantes y es estable durante al menos seis meses cuando se la almacena a una temperatura de entre 5ºC ± 3ºC y 25ºC ± 2ºC.
ARP130103855A 2012-10-24 2013-10-23 Soluciones midriaticas y antiinflamatorias inyectables, estables y libres de conservantes AR093115A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261718026P 2012-10-24 2012-10-24
US201261736179P 2012-12-12 2012-12-12

Publications (1)

Publication Number Publication Date
AR093115A1 true AR093115A1 (es) 2015-05-20

Family

ID=50545210

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP130103855A AR093115A1 (es) 2012-10-24 2013-10-23 Soluciones midriaticas y antiinflamatorias inyectables, estables y libres de conservantes

Country Status (40)

Country Link
US (6) US9066856B2 (es)
EP (2) EP3909572A1 (es)
JP (8) JP6017053B2 (es)
KR (4) KR102496463B1 (es)
CN (2) CN104822265A (es)
AP (1) AP2015008459A0 (es)
AR (1) AR093115A1 (es)
AU (1) AU2013201465B2 (es)
BR (1) BR112015009228B1 (es)
CA (1) CA2887772C (es)
CL (1) CL2015001078A1 (es)
CR (1) CR20150233A (es)
CU (1) CU20150037A7 (es)
CY (1) CY1124481T1 (es)
DK (1) DK2911511T3 (es)
EA (1) EA033811B1 (es)
ES (1) ES2875432T3 (es)
GE (1) GEP20186891B (es)
HK (1) HK1213434A1 (es)
HR (1) HRP20210980T1 (es)
HU (1) HUE055537T2 (es)
IL (1) IL238439B2 (es)
IN (1) IN2015DN03029A (es)
LT (1) LT2911511T (es)
MA (1) MA38096B1 (es)
MD (1) MD20150050A2 (es)
MX (2) MX2015005089A (es)
MY (1) MY188474A (es)
NZ (1) NZ628398A (es)
PE (1) PE20150958A1 (es)
PH (1) PH12015500850B1 (es)
PL (1) PL2911511T3 (es)
PT (1) PT2911511T (es)
RS (1) RS62188B1 (es)
SG (1) SG11201502602WA (es)
SI (1) SI2911511T1 (es)
SM (1) SMT202100393T1 (es)
UA (1) UA114650C2 (es)
WO (1) WO2014066485A1 (es)
ZA (1) ZA201502684B (es)

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US20210346318A1 (en) * 2013-10-03 2021-11-11 Harrow Ip, Llc Epinephrine-based ophthalmic compositions for intraocular administration and methods for fabricating thereof
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US20240058320A1 (en) * 2020-12-17 2024-02-22 Harrow Ip, Llc Mydriatic compositions and methods for fabricating thereof
CN115368310A (zh) 2021-05-18 2022-11-22 奥库菲尔医药公司 合成甲磺酸酚妥拉明的方法
US11883382B2 (en) 2021-07-23 2024-01-30 Somerset Therapeutics, Llc Buffer-free ophthalmological compositions of ketorolac and phenylephrine and applications thereof
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CN115950992B (zh) * 2023-03-15 2023-06-09 苏州朗易生物医药研究有限公司 一种去氧肾上腺素酮咯酸溶液中有关物质的检测方法及其应用

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