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AR085279A1 - Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico - Google Patents

Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico

Info

Publication number
AR085279A1
AR085279A1 ARP120100546A ARP120100546A AR085279A1 AR 085279 A1 AR085279 A1 AR 085279A1 AR P120100546 A ARP120100546 A AR P120100546A AR P120100546 A ARP120100546 A AR P120100546A AR 085279 A1 AR085279 A1 AR 085279A1
Authority
AR
Argentina
Prior art keywords
compound
formula
piridina
carbonil
phenil
Prior art date
Application number
ARP120100546A
Other languages
English (en)
Inventor
Ralph Diodone
Karsten Fahnrich
Shan Kuang
Gary C Ming-Visor
Baoshu Zhao
Prabha N Ibrahim
Original Assignee
Plexxikon Inc
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Plexxikon Inc, Hoffmann La Roche filed Critical Plexxikon Inc
Publication of AR085279A1 publication Critical patent/AR085279A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Pyrrole Compounds (AREA)

Abstract

Reivindicación 1: Una forma sólida del compuesto de la fórmula (1), dicha forma sólida está seleccionada a partir del grupo que consiste de: a) una forma esencialmente amórfica del compuesto de fórmula (1) seleccionada a partir de las formas XVII, XVIII, XIX, XX, XXI, XXII, XXIII, XXIV, XXV, XXVI o sus combinaciones, en la cual el compuesto de fórmula (1) está molecularmente dispersado; b) un solvato de las formas III, IV, V, VI, VII, IX, X, XI, XII, XIII, XIV o XV; c) a polimorfo de las formas VIII o XVI; y d) la sal de ácido sulfúrico, ácido bromhídrico o ácido clorhídrico del compuesto de fórmula (1).
ARP120100546A 2011-02-21 2012-02-17 Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico AR085279A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161444866P 2011-02-21 2011-02-21

Publications (1)

Publication Number Publication Date
AR085279A1 true AR085279A1 (es) 2013-09-18

Family

ID=47217568

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120100546A AR085279A1 (es) 2011-02-21 2012-02-17 Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico

Country Status (17)

Country Link
US (1) US8865735B2 (es)
EP (2) EP2678075A4 (es)
JP (2) JP2014505740A (es)
KR (1) KR20140011340A (es)
CN (2) CN103442767A (es)
AR (1) AR085279A1 (es)
AU (1) AU2012259422B2 (es)
BR (1) BR112013021103A2 (es)
CA (1) CA2827708A1 (es)
IL (1) IL227862A0 (es)
MX (1) MX2013009558A (es)
MY (1) MY163083A (es)
RU (1) RU2013143010A (es)
SG (1) SG192722A1 (es)
TW (1) TWI558702B (es)
WO (1) WO2012161776A1 (es)
ZA (1) ZA201306237B (es)

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