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AR070301A1 - Compuesto epoxi y metodo para producir el mismo - Google Patents

Compuesto epoxi y metodo para producir el mismo

Info

Publication number
AR070301A1
AR070301A1 ARP080101894A ARP080101894A AR070301A1 AR 070301 A1 AR070301 A1 AR 070301A1 AR P080101894 A ARP080101894 A AR P080101894A AR P080101894 A ARP080101894 A AR P080101894A AR 070301 A1 AR070301 A1 AR 070301A1
Authority
AR
Argentina
Prior art keywords
group
phenyl
substituted
halogen
substituent
Prior art date
Application number
ARP080101894A
Other languages
English (en)
Inventor
Yoshikazu Haraguchi
Shinichi Taira
Hidetsugu Tsubouchi
Satoshi Hayakawa
Naoto Utsumi
Takuya Furuta
Nobuhisa Fujita
Yoshihisa Tanada
Koichi Shinhama
Kimiyoshi Annka
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of AR070301A1 publication Critical patent/AR070301A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Reivindicacion 1: Un compuesto epoxi o una sal del mismo, caracterizado por la formula general (2) donde R1 representa hidrogeno o un grupo alquilo inferior; R2 representa un grupo piperidilo representado por la formula general (A1) (donde R3 representa: (A1a) un grupo fenoxi que tiene grupo(s) alcoxi inferiores sustituidos con halogeno como sustituyente(s) sobre un grupo fenilo, (A1b) un grupo alquilo interior sustituido con fenoxi que tiene grupo(s) alquilo interiores sustituidos con halogeno como sustituyente(s) sobre un grupo fenilo, (A1c) un grupo alcoxi inferior alquilo inferior sustituido con fenilo que tiene halogeno(s) como sustituyente(s) sobre un grupo fenilo, (A1d) un grupo alquilo inferior sustituido con fenilo que tiene grupo(s) alcoxi inferiores sustituidos con halogeno como sustituyente(s) sobre un grupo fenilo, (A1e) un grupo amino que tiene un grupo fenilo que tiene grupo(s) alcoxi inferiores sustituidos con halogeno como sustituyente(s) sobre un grupo fenilo, y un grupo alquilo inferior, o (A1f) un grupo alcoxi inferior sustituido con fenilo que tiene grupo(s) alcoxi inferiores sustituidos con halogeno como sustituyente(s) sobre un grupo fenilo), o un grupo piperazilo representado por la formula general (A2) (donde a4 representa: (A2a) un grupo alquenilo inferior sustituido con fenilo que tiene grupo(s) alcoxi inferiores sustituidos con halogeno como sustituyente(s) sobre un grupo fenilo, o (A2b) un grupo fenilo sustituido con halogeno); y n representa un numero entero de 1 a 6.
ARP080101894A 2007-05-08 2008-05-05 Compuesto epoxi y metodo para producir el mismo AR070301A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2007123097 2007-05-08

Publications (1)

Publication Number Publication Date
AR070301A1 true AR070301A1 (es) 2010-03-31

Family

ID=39683776

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP080101894A AR070301A1 (es) 2007-05-08 2008-05-05 Compuesto epoxi y metodo para producir el mismo

Country Status (27)

Country Link
US (2) US8344148B2 (es)
EP (1) EP2144899B1 (es)
JP (1) JP4971343B2 (es)
KR (1) KR101191072B1 (es)
CN (1) CN101675044B (es)
AR (1) AR070301A1 (es)
AT (1) ATE536352T1 (es)
AU (1) AU2008250097B2 (es)
BR (1) BRPI0810780A2 (es)
CA (1) CA2686092C (es)
CO (1) CO6260137A2 (es)
CY (1) CY1112279T1 (es)
DK (1) DK2144899T3 (es)
ES (1) ES2375245T3 (es)
HK (1) HK1137023A1 (es)
HR (1) HRP20120091T1 (es)
IL (1) IL201976A (es)
MX (1) MX2009011888A (es)
MY (1) MY149301A (es)
NZ (1) NZ580918A (es)
PL (1) PL2144899T3 (es)
PT (1) PT2144899E (es)
RU (1) RU2459822C2 (es)
SI (1) SI2144899T1 (es)
TW (1) TWI432428B (es)
UA (1) UA99455C2 (es)
WO (1) WO2008140090A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008053240A1 (de) 2008-10-25 2010-04-29 Saltigo Gmbh Herstellung von (N-Heterozyklyl)-Arylethern
TW201200523A (en) 2010-01-29 2012-01-01 Otsuka Pharma Co Ltd Synthetic intermediate of oxazole compound and method for producing the same
US20160280637A1 (en) * 2013-11-05 2016-09-29 Yokohama City University Superelastic material and energy storage material, energy absorption material, elastic material, actuator, and shape memory material that use said superelastic material
SI3119757T1 (en) 2014-03-17 2018-08-31 Pfizer Inc. DIACILGLICEROL-ACILTRANSFERAZE 2 BINDERS FOR THE USE IN THE TREATMENT OF PRECIOUS AND RELATED DISEASES
US10227362B2 (en) 2015-01-29 2019-03-12 Medshine Discovery Inc. Anti-pulmonary tuberculosis nitroimidazole derivative
EA201792154A1 (ru) * 2015-03-27 2018-02-28 Оцука Фармасьютикал Ко., Лтд. Способ получения 1-(4-гидроксифенил)-4-(4- трифторметоксифенокси)пиперидина или его соли

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8302696A1 (es) * 1982-05-19 1983-02-01 Romikim S A Procedimiento de preparacion de la cis-1-acetil-4 4-4-(2,4-diclorofenil)-2-(1h-imidazol-1-ilmetil)-1,3-dioxolano-4-ilmetoxi-fenil piperacina.
WO2001034569A1 (fr) * 1999-11-11 2001-05-17 Senju Pharmaceutical Co., Ltd. Medicaments contre la pancreatite
TWI347946B (en) * 2002-10-11 2011-09-01 Otsuka Pharma Co Ltd 2,3-dihydro-6-nitroimidazo[2,1-b]oxazole compound
BR0313566A (pt) 2002-10-15 2005-06-21 Otsuka Pharma Co Ltd Composto de 4-nitroimidazol 1-substituìdo, método para preparar um composto de 4-nitroimidazol, método para preparar um composto de 4-nitroimidazol 1-substituìdo, derivado de 4-nitroimidazol, e, composto
PL1678185T3 (pl) 2003-10-31 2009-04-30 Otsuka Pharma Co Ltd Związki 2,3-dihydro-6-nitroimidazo[2,1-B]oksazolu do leczenia gruźlicy
JP4787529B2 (ja) * 2004-04-09 2011-10-05 大塚製薬株式会社 医薬組成物
JP2009269859A (ja) * 2008-05-08 2009-11-19 Otsuka Pharmaceut Co Ltd Ｎ−含有複素環化合物

Also Published As

Publication number Publication date
KR20090010943A (ko) 2009-01-30
CN101675044A (zh) 2010-03-17
BRPI0810780A2 (pt) 2014-10-29
ES2375245T3 (es) 2012-02-28
HK1137023A1 (en) 2010-07-16
EP2144899B1 (en) 2011-12-07
WO2008140090A1 (en) 2008-11-20
CA2686092C (en) 2015-04-28
TWI432428B (zh) 2014-04-01
PT2144899E (pt) 2011-12-27
NZ580918A (en) 2011-09-30
UA99455C2 (ru) 2012-08-27
EP2144899A1 (en) 2010-01-20
CO6260137A2 (es) 2011-03-22
CY1112279T1 (el) 2015-12-09
CN101675044B (zh) 2012-10-03
US20130072683A1 (en) 2013-03-21
MY149301A (en) 2013-08-30
HRP20120091T1 (hr) 2012-02-29
RU2459822C2 (ru) 2012-08-27
US8552188B2 (en) 2013-10-08
AU2008250097A1 (en) 2008-11-20
IL201976A0 (en) 2010-06-16
SI2144899T1 (sl) 2012-03-30
JP2009534291A (ja) 2009-09-24
CA2686092A1 (en) 2008-11-20
ATE536352T1 (de) 2011-12-15
US20100217005A1 (en) 2010-08-26
DK2144899T3 (da) 2012-02-13
IL201976A (en) 2015-05-31
PL2144899T3 (pl) 2012-04-30
AU2008250097B2 (en) 2011-07-14
RU2009145273A (ru) 2011-06-20
KR101191072B1 (ko) 2012-10-15
MX2009011888A (es) 2009-11-18
TW200911793A (en) 2009-03-16
JP4971343B2 (ja) 2012-07-11
US8344148B2 (en) 2013-01-01

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