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AR063640A1 - Anticuerpos agonistas de trkb y usos de los mismos - Google Patents

Anticuerpos agonistas de trkb y usos de los mismos

Info

Publication number
AR063640A1
AR063640A1 ARP070105005A ARP070105005A AR063640A1 AR 063640 A1 AR063640 A1 AR 063640A1 AR P070105005 A ARP070105005 A AR P070105005A AR P070105005 A ARP070105005 A AR P070105005A AR 063640 A1 AR063640 A1 AR 063640A1
Authority
AR
Argentina
Prior art keywords
same
agonist antibodies
trkb agonist
trkb
antibodies
Prior art date
Application number
ARP070105005A
Other languages
English (en)
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Publication of AR063640A1 publication Critical patent/AR063640A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75Agonist effect on antigen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se dan a conocer anticuerpos agonistas de TrkB y métodos para su uso.
ARP070105005A 2006-11-09 2007-11-09 Anticuerpos agonistas de trkb y usos de los mismos AR063640A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85816906P 2006-11-09 2006-11-09

Publications (1)

Publication Number Publication Date
AR063640A1 true AR063640A1 (es) 2009-02-04

Family

ID=39365312

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP070105005A AR063640A1 (es) 2006-11-09 2007-11-09 Anticuerpos agonistas de trkb y usos de los mismos

Country Status (27)

Country Link
US (1) US20100150914A1 (es)
EP (1) EP2087007A2 (es)
JP (1) JP2010509354A (es)
KR (1) KR20090088896A (es)
CN (1) CN101573381A (es)
AR (1) AR063640A1 (es)
AU (1) AU2007316418A1 (es)
BR (1) BRPI0719000A2 (es)
CA (1) CA2669205A1 (es)
CL (1) CL2007003236A1 (es)
CO (1) CO6180432A2 (es)
CR (1) CR10779A (es)
DO (1) DOP2009000102A (es)
EA (1) EA200970469A1 (es)
EC (1) ECSP099392A (es)
IL (1) IL198468A0 (es)
MA (1) MA30922B1 (es)
MX (1) MX2009004881A (es)
NI (1) NI200900081U (es)
NO (1) NO20092217L (es)
PE (1) PE20081168A1 (es)
RU (1) RU2009121641A (es)
SM (1) SMAP200900040A (es)
TN (1) TN2009000181A1 (es)
TW (1) TW200829270A (es)
WO (1) WO2008058127A2 (es)
ZA (1) ZA200902943B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100089851A (ko) * 2007-10-23 2010-08-12 노파르티스 아게 호흡기 질환의 치료를 위한 trkb 항체의 용도
US8642035B2 (en) * 2008-01-17 2014-02-04 Irm Llc Anti-TrkB antibodies
US8748493B2 (en) * 2009-03-20 2014-06-10 Institut National De La Sante Et De La Recherche Medicale (Inserm) Inhibitors of cathepsin S for prevention or treatment of obesity-associated disorders
GB2491106A (en) 2011-05-18 2012-11-28 Univ Basel Antibodies against tropomyosin-related kinase B receptors
EP2788027A2 (en) * 2011-12-09 2014-10-15 Novo Nordisk A/S Glp-1 agonists
CN102944674B (zh) * 2012-11-05 2014-10-22 武汉远征世纪制药有限公司 一种检测TrkB受体pan-Tyr位点活性的ELISA试剂盒及其使用方法
CN102901815B (zh) * 2012-11-05 2014-10-22 武汉远征世纪制药有限公司 一种检测TrkB受体816/817位酪氨酸位点活性的ELISA试剂盒及其使用方法
WO2015173756A2 (en) 2014-05-16 2015-11-19 Pfizer Inc. Bispecific antibodies
CN104524568B (zh) * 2015-01-08 2018-04-20 中国人民解放军第二军医大学 一种治疗肥胖症的药物组合物及其应用
EP3328898B8 (en) 2015-07-28 2024-04-10 6452728 Canada Corp. Trkb or trkc agonist compositions and methods for the treatment of otic conditions
CA3005491A1 (en) * 2015-11-17 2017-05-26 Glaxosmithkline Intellectual Property Development Limited Binding agonists for treatment of neurological and other disorders
US9914781B1 (en) 2016-11-08 2018-03-13 Glaxosmithkline Intellectual Property Development Limited Binding agonist for treatment of neurological and other disorders
WO2018195008A1 (en) * 2017-04-21 2018-10-25 Mellitus, Llc Methods and antibodies for diabetes-related applications
US10793634B2 (en) * 2017-06-09 2020-10-06 Boehringer Ingelheim International Gmbh Anti-TrkB antibodies
EA202090966A1 (ru) 2017-11-30 2020-08-26 Ридженерон Фармасьютикалз, Инк. МОНОКЛОНАЛЬНЫЕ АНТИ-TrkB АНТИТЕЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
EP3759145A4 (en) * 2018-02-26 2022-03-09 Minerva Biotechnologies Corporation DIAGNOSTIC METHODS USING ANTI-MUC1* ANTIBODIES
CN110818797B (zh) * 2018-08-09 2022-11-04 东莞市朋志生物科技有限公司 一种抗人ca153蛋白的重组抗体
WO2022084354A1 (en) 2020-10-21 2022-04-28 Boehringer Ingelheim International Gmbh Bispecific anti-vegf and anti-trkb binding molecules for the treatment of eye diseases
WO2023125485A1 (en) * 2021-12-28 2023-07-06 4B Technologies (Beijing) Co., Limited TrkB ANTIBODY AND APPLICATION THEREOF

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340288C (en) 1988-09-02 1998-12-29 Robert Charles Ladner Generation and selection of novel binding proteins
AU7247191A (en) 1990-01-11 1991-08-05 Molecular Affinities Corporation Production of antibodies using gene libraries
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
DE69233367T2 (de) 1991-04-10 2005-05-25 The Scripps Research Institute, La Jolla Bibliotheken heterodimerer rezeptoren mittels phagemiden
DK1024191T3 (da) 1991-12-02 2008-12-08 Medical Res Council Fremstilling af autoantistoffer fremvist på fag-overflader ud fra antistofsegmentbiblioteker
AU696293B2 (en) 1993-12-08 1998-09-03 Genzyme Corporation Process for generating specific antibodies
ATE243745T1 (de) 1994-01-31 2003-07-15 Univ Boston Bibliotheken aus polyklonalen antikörpern
US5601820A (en) * 1994-07-07 1997-02-11 Children's Hospital Of Philadelphia Compositions and methods of making and using human full length TRK-B
CN101273064A (zh) * 2005-06-06 2008-09-24 惠氏公司 抗-TrkB单克隆抗体及其用途
JP2009525319A (ja) * 2006-02-02 2009-07-09 ライナット ニューロサイエンス コーポレイション trkBアンタゴニストを投与することにより肥満を治療する方法
TW200808352A (en) * 2006-02-02 2008-02-16 Rinat Neuroscience Corp Methods for treating unwanted weight loss or eating disorders by administering a TRKB agonist

Also Published As

Publication number Publication date
ECSP099392A (es) 2009-07-31
KR20090088896A (ko) 2009-08-20
EP2087007A2 (en) 2009-08-12
WO2008058127A9 (en) 2008-08-21
NO20092217L (no) 2009-06-09
CO6180432A2 (es) 2010-07-19
AU2007316418A1 (en) 2008-05-15
DOP2009000102A (es) 2010-10-31
ZA200902943B (en) 2010-05-26
CL2007003236A1 (es) 2008-06-13
CA2669205A1 (en) 2008-05-15
SMAP200900040A (it) 2010-01-19
RU2009121641A (ru) 2010-12-20
WO2008058127A3 (en) 2008-10-02
TN2009000181A1 (en) 2010-10-18
EA200970469A1 (ru) 2010-04-30
PE20081168A1 (es) 2008-09-22
BRPI0719000A2 (pt) 2013-12-10
TW200829270A (en) 2008-07-16
MX2009004881A (es) 2009-05-21
NI200900081U (es) 2010-03-16
IL198468A0 (en) 2011-08-01
US20100150914A1 (en) 2010-06-17
JP2010509354A (ja) 2010-03-25
CN101573381A (zh) 2009-11-04
MA30922B1 (fr) 2009-11-02
WO2008058127A2 (en) 2008-05-15
CR10779A (es) 2009-07-03

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