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AR015120A1 - PHARMACEUTICAL COMPOSITION THAT INCLUDES 5- [4- [2- (N-METHYL-N- (2-PIRIDIL) AMINO) ETOXI] BENCIL] -TIAZOLIDIN-2,4-DIONA, A PROCEDURE FOR PREPARATION, AND A PREPARATION FOR PRE -PHARMACEUTICAL ADMINISTRATION - Google Patents

PHARMACEUTICAL COMPOSITION THAT INCLUDES 5- [4- [2- (N-METHYL-N- (2-PIRIDIL) AMINO) ETOXI] BENCIL] -TIAZOLIDIN-2,4-DIONA, A PROCEDURE FOR PREPARATION, AND A PREPARATION FOR PRE -PHARMACEUTICAL ADMINISTRATION

Info

Publication number
AR015120A1
AR015120A1 ARP980102650A ARP980102650A AR015120A1 AR 015120 A1 AR015120 A1 AR 015120A1 AR P980102650 A ARP980102650 A AR P980102650A AR P980102650 A ARP980102650 A AR P980102650A AR 015120 A1 AR015120 A1 AR 015120A1
Authority
AR
Argentina
Prior art keywords
preparation
amino
methyl
tiazolidin
piridil
Prior art date
Application number
ARP980102650A
Other languages
Spanish (es)
Original Assignee
Smithkline Beecham Plc
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9712851.6A external-priority patent/GB9712851D0/en
Application filed by Smithkline Beecham Plc, Smithkline Beecham Corp filed Critical Smithkline Beecham Plc
Publication of AR015120A1 publication Critical patent/AR015120A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Una composicion farmacéutica que comprende 5-[4-(2-(N-metil-N-(2-Piridil) amino)etoxi]bencil]-tiazolidin-2,4-diona [de aqui en adelante compuesto (I)]que la composicion comprende 2 a 12mg de Compuesto (I) en una forma farmacéuticamenteaceptable y opcionalmente un vehículo farmacéuticamenteaceptable para el mismo, un procedimiento para su preparacion y una composicion para la pre-administracion farmacéuticaA pharmaceutical composition comprising 5- [4- (2- (N-methyl-N- (2-Pyridyl) amino) ethoxy] benzyl] -thiazolidin-2,4-dione [hereinafter compound (I)]) which The composition comprises 2 to 12mg of Compound (I) in a pharmaceutically acceptable form and optionally a pharmaceutically acceptable carrier thereof, a process for its preparation and a composition for pharmaceutical pre-administration.

ARP980102650A 1997-06-05 1998-06-04 PHARMACEUTICAL COMPOSITION THAT INCLUDES 5- [4- [2- (N-METHYL-N- (2-PIRIDIL) AMINO) ETOXI] BENCIL] -TIAZOLIDIN-2,4-DIONA, A PROCEDURE FOR PREPARATION, AND A PREPARATION FOR PRE -PHARMACEUTICAL ADMINISTRATION AR015120A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9711683.4A GB9711683D0 (en) 1997-06-05 1997-06-05 Composition
GBGB9712851.6A GB9712851D0 (en) 1997-06-18 1997-06-18 Composition

Publications (1)

Publication Number Publication Date
AR015120A1 true AR015120A1 (en) 2001-04-18

Family

ID=26311662

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP980102650A AR015120A1 (en) 1997-06-05 1998-06-04 PHARMACEUTICAL COMPOSITION THAT INCLUDES 5- [4- [2- (N-METHYL-N- (2-PIRIDIL) AMINO) ETOXI] BENCIL] -TIAZOLIDIN-2,4-DIONA, A PROCEDURE FOR PREPARATION, AND A PREPARATION FOR PRE -PHARMACEUTICAL ADMINISTRATION
ARP980102649A AR008198A1 (en) 1997-06-05 1998-06-04 PROCEDURE FOR PREPARING A PHARMACEUTICAL COMPOSITION OF 5- [4- [2- (N- METHYL-N- (2-PIRIDIL) AMINO) ETOXI] BENCIL] THIAZOLIN-2,4-DIONA

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP980102649A AR008198A1 (en) 1997-06-05 1998-06-04 PROCEDURE FOR PREPARING A PHARMACEUTICAL COMPOSITION OF 5- [4- [2- (N- METHYL-N- (2-PIRIDIL) AMINO) ETOXI] BENCIL] THIAZOLIN-2,4-DIONA

Country Status (29)

Country Link
EP (1) EP0998284A1 (en)
JP (1) JP2001521553A (en)
KR (1) KR20010013410A (en)
CN (3) CN1526391A (en)
AP (1) AP1214A (en)
AR (2) AR015120A1 (en)
AU (1) AU8215098A (en)
BG (1) BG104048A (en)
BR (1) BR9810405A (en)
CA (2) CA2292629C (en)
CO (1) CO4940400A1 (en)
DZ (1) DZ2510A1 (en)
EA (1) EA002384B1 (en)
GB (1) GB9711683D0 (en)
HU (1) HUP0004070A3 (en)
ID (1) ID24264A (en)
IL (1) IL133074A0 (en)
MX (1) MXPA99011322A (en)
NO (2) NO995938L (en)
NZ (2) NZ523725A (en)
OA (1) OA11306A (en)
PE (1) PE78899A1 (en)
PL (1) PL337201A1 (en)
SK (1) SK164899A3 (en)
TR (2) TR199902963T2 (en)
TW (1) TW570797B (en)
UY (1) UY25032A1 (en)
WO (1) WO1998055122A1 (en)
ZA (2) ZA984826B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20010040A1 (en) 1999-04-23 2001-03-10 Smithkline Beecham Plc SALT POLYMORPH OF MALEIC ACID OF 5- [4- [2- (N-METHYL-N- (2-PYRIDYL) AMINO) ETHOXY] BENZYL] -THAZOLIDINE-2,4-DIONA
US20040248945A1 (en) 1999-04-23 2004-12-09 Smithkline Beecham P.L.C. Thiazolidinedione derivative and its use as antidiabetic
ATE246191T1 (en) 1999-04-23 2003-08-15 Smithkline Beecham Plc POLYMORPHOUS OF 5-(4-(2-(N-METHYL-N-(2-PYRDYL)AMINO)ETHOXY)BENZYL)THIAZOLIDINE-2,4-DIONE MALEIC ACID SALT
GB0021978D0 (en) 2000-09-07 2000-10-25 Smithkline Beecham Plc Novel pharmaceutical
GB0127805D0 (en) * 2001-11-20 2002-01-09 Smithkline Beecham Plc Pharmaceutical composition
AU2002350965A1 (en) * 2001-12-13 2003-06-23 Smithkline Beecham Plc Toluenesulfonate hydrates of a thiazolidinedione derivative
GB0129876D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
GB0129871D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
GB0130509D0 (en) * 2001-12-20 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
US7435741B2 (en) 2006-05-09 2008-10-14 Teva Pharmaceutical Industries, Ltd. 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
DE06252444T8 (en) * 2006-05-09 2009-03-19 Teva Pharmaceutical Industries Ltd. 2-N- {5 - [[4- [2- (Methyl-2-pyridinylamino) -ethoxy] -phenyl] -methyl] -2,4-thiazolidinedione-succinic acid, method of preparation and compositions with rosiglitazone maleate
WO2015008234A1 (en) * 2013-07-17 2015-01-22 Glenmark Pharmaceuticals S.A. Bicyclic heterocyclic compounds as ror gamma modulators

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3856378T2 (en) * 1987-09-04 2000-05-11 Beecham Group P.L.C., Brentford Substituted thiazolidinedione derivatives
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
WO1995021608A1 (en) * 1994-02-10 1995-08-17 Smithkline Beecham Plc Use of insulin sensitisers for treating renal diseases
KR19990036290A (en) * 1995-08-10 1999-05-25 로즈 암스트롱 Reduction of Exogenous Insulin Dosage in Non-insulin-Dependent Diabetic Patients
AU7604596A (en) * 1995-11-17 1997-06-11 Warner-Lambert Company A method of treating myotonic dystrophy
NZ314406A (en) * 1996-03-18 2000-12-22 Sankyo Co Treatment or prophylaxis of pancreatitis with a medicament containing an insulin sensitiser including oxazoles and thiazoles
EP0921798A1 (en) * 1996-07-12 1999-06-16 Smithkline Beecham Plc Novel treatment of leptine resistance

Also Published As

Publication number Publication date
JP2001521553A (en) 2001-11-06
NO995938D0 (en) 1999-12-03
EA199901116A1 (en) 2000-06-26
PL337201A1 (en) 2000-08-14
BR9810405A (en) 2000-08-29
AP1214A (en) 2003-10-08
WO1998055122A1 (en) 1998-12-10
CN1430959A (en) 2003-07-23
CA2292629A1 (en) 1998-12-10
AU8215098A (en) 1998-12-21
IL133074A0 (en) 2001-03-19
ID24264A (en) 2000-07-13
PE78899A1 (en) 1999-10-22
CA2292629C (en) 2004-01-06
KR20010013410A (en) 2001-02-26
BG104048A (en) 2000-07-31
NZ513922A (en) 2001-09-28
ZA984826B (en) 1999-08-03
NZ523725A (en) 2004-09-24
CO4940400A1 (en) 2000-07-24
UY25032A1 (en) 1998-11-26
HUP0004070A2 (en) 2002-02-28
SK164899A3 (en) 2000-11-07
ZA9811572B (en) 1999-07-22
DZ2510A1 (en) 2003-01-25
TR199902963T2 (en) 2000-02-21
TR200002790T2 (en) 2001-11-21
CN1259050A (en) 2000-07-05
AP9901696A0 (en) 1999-12-31
EA002384B1 (en) 2002-04-25
TW570797B (en) 2004-01-11
NO995938L (en) 2000-02-02
CN1526391A (en) 2004-09-08
CN1112926C (en) 2003-07-02
HUP0004070A3 (en) 2002-03-28
GB9711683D0 (en) 1997-08-06
AR008198A1 (en) 1999-12-29
MXPA99011322A (en) 2004-12-02
OA11306A (en) 2003-10-22
EP0998284A1 (en) 2000-05-10
CA2333352A1 (en) 1998-12-10
NO20040738L (en) 2000-02-02

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