AP365A - Novel steroid esters. - Google Patents

Novel steroid esters. Download PDF

Info

Publication number: AP365A
Authority: AP; ARIPO
Prior art keywords: hydrogen; compound; carbon atoms; dione; formula
Prior art date: 1991-02-04

Application number

APAP/P/1992/000354A

Other languages

English (en)

Other versions

AP9200354A0 (en

Inventor

Bengt Ingemar Axelsson

Ralph Lennart Brattsand

Leif Arne Kallstorm

Bror Arne Thalen

Original Assignee

Ab Astra

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-02-04

Filing date

1992-01-27

Publication date

1994-10-21

1992-01-27 Application filed by Ab Astra filed Critical Ab Astra

1992-01-31 Publication of AP9200354A0 publication Critical patent/AP9200354A0/xx

1994-10-21 Application granted granted Critical

1994-10-21 Publication of AP365A publication Critical patent/AP365A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Immunology (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)

APAP/P/1992/000354A 1991-02-04 1992-01-27 Novel steroid esters. AP365A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
SE9100342A SE9100342D0 (sv)	1991-02-04	1991-02-04	Novel steroid esters

Publications (2)

Publication Number	Publication Date
AP9200354A0 AP9200354A0 (en)	1992-01-31
AP365A true AP365A (en)	1994-10-21

Family

ID=20381807

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
APAP/P/1992/000354A AP365A (en)	1991-02-04	1992-01-27	Novel steroid esters.

Country Status (38)

Country	Link
US (1)	US5614514A (xx)
EP (1)	EP0572451B1 (xx)
JP (1)	JP2947933B2 (xx)
KR (1)	KR100205835B1 (xx)
CN (3)	CN1039329C (xx)
AP (1)	AP365A (xx)
AT (1)	ATE164589T1 (xx)
BG (1)	BG61816B1 (xx)
CA (1)	CA2100453A1 (xx)
CZ (1)	CZ282057B6 (xx)
DE (1)	DE69224982T2 (xx)
DK (1)	DK0572451T3 (xx)
DZ (1)	DZ1554A1 (xx)
EE (1)	EE03110B1 (xx)
ES (1)	ES2114931T3 (xx)
FI (1)	FI933451A (xx)
HK (1)	HK1004335A1 (xx)
HU (1)	HU221168B1 (xx)
IE (1)	IE920167A1 (xx)
IL (1)	IL100542A (xx)
IS (1)	IS1653B (xx)
MA (1)	MA22407A1 (xx)
MX (1)	MX9200374A (xx)
MY (1)	MY111502A (xx)
NO (1)	NO304074B1 (xx)
NZ (1)	NZ241211A (xx)
PL (1)	PL170383B1 (xx)
PT (1)	PT100087B (xx)
RO (1)	RO111272B1 (xx)
RU (1)	RU2112775C1 (xx)
SE (1)	SE9100342D0 (xx)
SK (1)	SK281802B6 (xx)
TN (1)	TNSN92008A1 (xx)
TW (1)	TW287166B (xx)
UA (1)	UA43825C2 (xx)
WO (1)	WO1992013873A1 (xx)
YU (1)	YU48893B (xx)
ZA (1)	ZA92234B (xx)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE9100341D0 (sv) *	1991-02-04	1991-02-04	Astra Ab	Novel steroids
NZ259596A (en) *	1993-01-08	1997-04-24	Astra Ab	Sugar-substituted glucocorticosteroid and use in medicaments specific to the colon or ileum
US5983956A (en) *	1994-10-03	1999-11-16	Astra Aktiebolag	Formulation for inhalation
US5980949A (en) *	1994-10-03	1999-11-09	Astra Aktiebolag	Formulation for inhalation
SE9700135D0 (sv)	1997-01-20	1997-01-20	Astra Ab	New formulation
SE9700133D0 (sv) *	1997-01-20	1997-01-20	Astra Ab	New formulation
GB9923076D0 (en)	1999-09-29	1999-12-01	Phytopharm Plc	Sapogenin derivatives and their use
AU4093799A (en)	1998-05-22	1999-12-13	Board Of Trustees Of The Leland Stanford Junior University	Bifunctional molecules and therapies based thereon
US7300667B1 (en)	1999-05-27	2007-11-27	Euro-Celtique, S.A.	Preparations for the application of anti-inflammatory, especially antiseptic agents and/or agents promoting the healing of wounds, to the lower respiratory tract
AU775500B2 (en)	1999-05-27	2004-08-05	Euro-Celtique S.A.	Preparations for the application of anti-infective and/or anti-inflammatory agents
HRP20010018A2 (en)	2001-01-09	2002-12-31	Pliva D D	Novel anti-inflammatory compounds
AU2003217535A1 (en)	2002-02-20	2003-09-09	Sepracor Inc.	Carbonate and carbamate modified forms of glucocorticoids
US20050009798A1 (en)	2002-02-20	2005-01-13	Sepracor Inc.	Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists
RU2330858C2 (ru)	2002-07-08	2008-08-10	Глаксомитклайн Истраживацки Центар Загреб Д.О.О.	Новые соединения, составы и способы лечения воспалительных заболеваний и состояний
AU2003264917A1 (en)	2002-07-08	2004-01-23	Pliva - Istrazivacki Institut D.O.O.	Hybrid molecules of macrolides with steroid/non-steroid anti-inflammatory, antineoplastic and antiviral active molecules
WO2004017904A2 (en) *	2002-08-23	2004-03-04	The Mclean Hospital Corporation	Corticosteroid conjugates and uses thereof
WO2004033478A2 (en) *	2002-10-08	2004-04-22	Sepracor Inc.	Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
HRP20030324A2 (en)	2003-04-24	2005-02-28	Pliva-Istra�iva�ki institut d.o.o.	Compounds of antiinflammatory effect
HRP20030604A2 (en)	2003-07-25	2005-04-30	Pliva-Istra�iva�ki institut d.o.o.	Substituted furochromenes, preparation thereof andtheir antiinflammatory action
HRP20030603A2 (en)	2003-07-25	2005-10-31	Pliva-Istra�iva�ki institut d.o.o.	Substituted furochromene compounds of antiinflammatory action
WO2005016352A1 (en) *	2003-08-05	2005-02-24	Sepracor Inc.	AMINO ACID AND PEPTIDE-MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH ß2 ADRENERGIC AGONISTS
CA2585711A1 (en)	2004-10-27	2006-05-04	Glaxosmithkline Istrazivacki Centar Zagreb D.O.O.	Conjugates with anti-inflammatory activity
CA2608144C (en)	2005-04-28	2012-11-13	Proteus Biomedical, Inc.	Pharma-informatics system
WO2007035716A2 (en)	2005-09-16	2007-03-29	Raptor Pharmaceutical Inc.	Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
ES2728225T3 (es)	2009-02-20	2019-10-23	2 Bbb Medicines B V	Sistema de administración de fármacos a base de glutatión
CA2760945A1 (en)	2009-05-06	2010-11-11	Laboratory Skin Care, Inc.	Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US8737506B1 (en)	2010-12-29	2014-05-27	Sprint Communications Company L.P.	Determination of transmit diversity transmission delays
US8437713B1 (en)	2011-02-16	2013-05-07	Sprint Communications Company L.P.	Wireless transmit diversity control by location of a wireless communication device
US8565686B2 (en)	2011-06-30	2013-10-22	Sprint Communications Company L.P.	Power status multipath search window sizing for wireless communications
TR201808592T4 (tr)	2012-02-10	2018-07-23	Taiwan Liposome Co Ltd	Oküler steroi̇d kompli̇kasyonlarinin azaltimina yöneli̇k farmasöti̇k bi̇leşi̇mler.
JP5965187B2 (ja) *	2012-03-30	2016-08-03	小林製薬株式会社	油性軟膏剤
CN109985048B (zh) *	2017-12-29	2021-06-29	广州市赛普特医药科技股份有限公司	2β,3α,5α-三羟基雄甾-6-酮用于炎症反应的治疗

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0170642A2 (en) *	1984-07-30	1986-02-05	Aktiebolaget Draco	Liposomes containing steroid esters
US4695625A (en) *	1984-06-11	1987-09-22	Sicor Societa Italiana Corticosteroidi S.P.A.	Process for the preparation of 16,17 acetals of pregnane derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3126375A (en) *		1964-03-24		Chioacyl
US3197469A (en) *	1958-08-06	1965-07-27	Pharmaceutical Res Products In	16, 17-acetals and ketals of 6-halo-16, 17-dihydroxy steroids of the pregnane seriesand intermediates therefor
US3048581A (en) *	1960-04-25	1962-08-07	Olin Mathieson	Acetals and ketals of 16, 17-dihydroxy steroids
US3357974A (en) *	1965-12-28	1967-12-12	Merck & Co Inc	Processes for preparing 16alpha, 17alpha-acetals and ketals of 16alpha, 17alpha, 21-trihydroxy-delta4-pregnene-3, 20-diones
US3758686A (en) *	1971-12-07	1973-09-11	American Cyanamid Co	Method of using steroid acetonides
SE378109B (xx) *	1972-05-19	1975-08-18	Bofors Ab
US3796701A (en) *	1973-02-26	1974-03-12	Squibb & Sons Inc	5alpha,9-oxazino steroids and 9-carboxamido steroids
SE8008524L (sv) *	1980-12-04	1982-06-05	Draco Ab	4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
US4304727A (en) *	1980-12-05	1981-12-08	The Upjohn Company	9α-Debromination
JPS58176485A (ja) *	1982-04-08	1983-10-15	Nippon Denso Co Ltd	可変容量圧縮機
US4749649A (en) *	1983-05-16	1988-06-07	The Upjohn Company	Microbial Δ1-dehydrogenation process using a scavenger of toxic oxygen
JPS6067496A (ja) *	1983-09-26	1985-04-17	Ota Seiyaku Kk	フルオシノロン１６，１７−アセトニド２１−ブチレ−トおよびその製造法

1991
- 1991-02-04 SE SE9100342A patent/SE9100342D0/xx unknown
- 1991-12-27 IL IL10054291A patent/IL100542A/xx not_active IP Right Cessation
- 1991-12-30 TW TW080110262A patent/TW287166B/zh active
1992
- 1992-01-06 NZ NZ241211A patent/NZ241211A/xx unknown
- 1992-01-13 ZA ZA92234A patent/ZA92234B/xx unknown
- 1992-01-21 IE IE016792A patent/IE920167A1/en not_active IP Right Cessation
- 1992-01-22 YU YU6492A patent/YU48893B/sh unknown
- 1992-01-22 DZ DZ920006A patent/DZ1554A1/fr active
- 1992-01-27 AP APAP/P/1992/000354A patent/AP365A/en active
- 1992-01-29 UA UA93004296A patent/UA43825C2/uk unknown
- 1992-01-29 ES ES92904423T patent/ES2114931T3/es not_active Expired - Lifetime
- 1992-01-29 SK SK797-93A patent/SK281802B6/sk unknown
- 1992-01-29 MX MX9200374A patent/MX9200374A/es unknown
- 1992-01-29 AT AT92904423T patent/ATE164589T1/de not_active IP Right Cessation
- 1992-01-29 DK DK92904423T patent/DK0572451T3/da active
- 1992-01-29 PL PL92300351A patent/PL170383B1/pl unknown
- 1992-01-29 RO RO93-01094A patent/RO111272B1/ro unknown
- 1992-01-29 HU HU9302243A patent/HU221168B1/hu not_active IP Right Cessation
- 1992-01-29 JP JP4504217A patent/JP2947933B2/ja not_active Expired - Fee Related
- 1992-01-29 CZ CS931495A patent/CZ282057B6/cs not_active IP Right Cessation
- 1992-01-29 KR KR1019930702299A patent/KR100205835B1/ko not_active IP Right Cessation
- 1992-01-29 DE DE69224982T patent/DE69224982T2/de not_active Expired - Fee Related
- 1992-01-29 EP EP92904423A patent/EP0572451B1/en not_active Expired - Lifetime
- 1992-01-29 CA CA002100453A patent/CA2100453A1/en not_active Abandoned
- 1992-01-29 WO PCT/SE1992/000056 patent/WO1992013873A1/en active IP Right Grant
- 1992-01-29 RU RU93053632A patent/RU2112775C1/ru active
- 1992-01-29 US US08/094,100 patent/US5614514A/en not_active Expired - Fee Related
- 1992-01-31 MY MYPI92000158A patent/MY111502A/en unknown
- 1992-02-03 PT PT100087A patent/PT100087B/pt not_active IP Right Cessation
- 1992-02-03 CN CN92100797A patent/CN1039329C/zh not_active Expired - Fee Related
- 1992-02-03 MA MA22693A patent/MA22407A1/fr unknown
- 1992-02-03 IS IS3809A patent/IS1653B/is unknown
- 1992-02-04 TN TNTNSN92008A patent/TNSN92008A1/fr unknown
1993
- 1993-08-02 NO NO932762A patent/NO304074B1/no not_active IP Right Cessation
- 1993-08-02 BG BG98011A patent/BG61816B1/bg unknown
- 1993-08-03 FI FI933451A patent/FI933451A/fi unknown
1994
- 1994-11-23 EE EE9400330A patent/EE03110B1/xx not_active IP Right Cessation
1996
- 1996-10-22 CN CN96122759A patent/CN1076607C/zh not_active Expired - Fee Related
- 1996-11-01 CN CN96114411A patent/CN1076606C/zh not_active Expired - Fee Related
1998
- 1998-04-24 HK HK98103446A patent/HK1004335A1/xx not_active IP Right Cessation

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4695625A (en) *	1984-06-11	1987-09-22	Sicor Societa Italiana Corticosteroidi S.P.A.	Process for the preparation of 16,17 acetals of pregnane derivatives
EP0170642A2 (en) *	1984-07-30	1986-02-05	Aktiebolaget Draco	Liposomes containing steroid esters

Also Published As

Publication number	Publication date
UA43825C2 (uk)	2002-01-15
ZA92234B (en)	1992-10-28
EP0572451B1 (en)	1998-04-01
MA22407A1 (fr)	1992-10-01
CN1076607C (zh)	2001-12-26
YU6492A (sh)	1994-12-28
FI933451A0 (fi)	1993-08-03
HU221168B1 (en)	2002-08-28
AP9200354A0 (en)	1992-01-31
PT100087A (pt)	1993-05-31
YU48893B (sh)	2002-10-18
CN1158726A (zh)	1997-09-10
RU2112775C1 (ru)	1998-06-10
JPH06505233A (ja)	1994-06-16
CN1039329C (zh)	1998-07-29
CN1155418A (zh)	1997-07-30
AU1235892A (en)	1992-09-07
HK1004335A1 (en)	1998-11-20
SK281802B6 (sk)	2001-08-06
NO932762D0 (no)	1993-08-02
NO932762L (no)	1993-08-02
IL100542A (en)	1997-02-18
CA2100453A1 (en)	1992-08-05
IL100542A0 (en)	1992-09-06
PL170383B1 (pl)	1996-12-31
SE9100342D0 (sv)	1991-02-04
AU661472B2 (en)	1995-07-27
TW287166B (xx)	1996-10-01
BG61816B1 (bg)	1998-06-30
DZ1554A1 (fr)	2002-02-17
HU9302243D0 (en)	1993-10-28
TNSN92008A1 (fr)	1993-06-08
PT100087B (pt)	1999-09-30
FI933451A (fi)	1993-08-03
NO304074B1 (no)	1998-10-19
ES2114931T3 (es)	1998-06-16
WO1992013873A1 (en)	1992-08-20
KR100205835B1 (ko)	1999-07-01
EP0572451A1 (en)	1993-12-08
JP2947933B2 (ja)	1999-09-13
CZ149593A3 (en)	1994-03-16
NZ241211A (en)	1993-08-26
US5614514A (en)	1997-03-25
SK79793A3 (en)	1994-03-09
DE69224982D1 (de)	1998-05-07
DE69224982T2 (de)	1998-07-30
CN1076606C (zh)	2001-12-26
CZ282057B6 (cs)	1997-05-14
MX9200374A (es)	1992-08-01
DK0572451T3 (da)	1998-10-19
CN1064078A (zh)	1992-09-02
IS1653B (is)	1997-06-20
RO111272B1 (ro)	1996-08-30
EE03110B1 (et)	1998-08-17
ATE164589T1 (de)	1998-04-15
IS3809A (is)	1992-08-05
BG98011A (bg)	1994-04-29
MY111502A (en)	2000-07-31
HUT64972A (en)	1994-03-28
IE920167A1 (en)	1992-08-12

Publication	Publication Date	Title
AP365A (en)	1994-10-21	Novel steroid esters.
EP0570454B1 (en)	1999-04-07	Novel steroids
US4693999A (en)	1987-09-15	Liposomes containing steroid esters
US5888995A (en)	1999-03-30	Steroid esters
AU661472C (en)	1996-06-27	Novel steroid esters
SI9210064A (sl)	1995-02-28	Nove antiinflamatorno in antialergijsko aktivne spojine, glukokortikosteroidi ter postopki za njihovo pripravo
AU661471C (en)	1997-10-09	Novel steroids
HRP920587A2 (en)	1995-10-31	Liposomes containing steroid esters a process for the preparation of stable camomile extract rich with active substances