AP3576A - Inhibitors of flaviviridae viruses - Google Patents

Inhibitors of flaviviridae viruses

Info

Publication number: AP3576A
Authority: AP; ARIPO
Prior art keywords: inhibitors; flaviviridae viruses; flaviviridae; viruses
Prior art date: 2010-01-15

Application number

AP2012006414A

Other languages

English (en)

Other versions

AP2012006414A0 (en

Inventor

Eda Canales

Michael O'neil Hanrahan Clarke

Scott E Lazerwith

Willard Lew

Philip Anthony Morganelli

William J Watkins

Original Assignee

Gilead Sciences Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2010-01-15

Filing date

2011-01-14

Publication date

2016-02-08

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43538203&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AP3576(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2011-01-14 Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc

2012-08-31 Publication of AP2012006414A0 publication Critical patent/AP2012006414A0/xx

2016-02-08 Application granted granted Critical

2016-02-08 Publication of AP3576A publication Critical patent/AP3576A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4436—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
General Chemical & Material Sciences (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

AP2012006414A 2010-01-15 2011-01-14 Inhibitors of flaviviridae viruses AP3576A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US29557610P	2010-01-15	2010-01-15
US35348110P	2010-06-10	2010-06-10
PCT/US2011/021335 WO2011088345A1 (en)	2010-01-15	2011-01-14	Inhibitors of flaviviridae viruses

Publications (2)

Publication Number	Publication Date
AP2012006414A0 AP2012006414A0 (en)	2012-08-31
AP3576A true AP3576A (en)	2016-02-08

Family

ID=43538203

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AP2012006414A AP3576A (en)	2010-01-15	2011-01-14	Inhibitors of flaviviridae viruses

Country Status (27)

Country	Link
US (2)	US8513298B2 (ko)
EP (2)	EP3219713A1 (ko)
JP (2)	JP5868872B2 (ko)
KR (1)	KR101727776B1 (ko)
CN (1)	CN102712633B (ko)
AP (1)	AP3576A (ko)
AR (1)	AR080001A1 (ko)
AU (1)	AU2011205744B2 (ko)
BR (1)	BR112012017382A2 (ko)
CA (1)	CA2785567C (ko)
CL (1)	CL2012001960A1 (ko)
CR (1)	CR20120417A (ko)
EA (1)	EA021196B1 (ko)
EC (1)	ECSP12012104A (ko)
ES (1)	ES2626150T3 (ko)
IL (1)	IL220545B (ko)
MX (1)	MX2012008211A (ko)
NZ (1)	NZ600817A (ko)
PE (1)	PE20130281A1 (ko)
PL (1)	PL2523950T3 (ko)
PT (1)	PT2523950T (ko)
SG (2)	SG10201500298PA (ko)
SI (1)	SI2523950T1 (ko)
TW (1)	TWI491609B (ko)
UY (1)	UY33183A (ko)
WO (1)	WO2011088345A1 (ko)
ZA (1)	ZA201205248B (ko)

Families Citing this family (27)

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JP5841531B2 (ja) *	2009-07-21	2016-01-13	ギリアードサイエンシーズ，インコーポレイテッド	フラビウイルス科ウイルスの阻害剤
CA2771124C (en)	2009-09-09	2019-01-15	Gilead Sciences, Inc.	Inhibitors of flaviviridae viruses
NZ600816A (en)	2010-01-15	2014-08-29	Gilead Sciences Inc	Inhibitors of flaviviridae viruses
SG10201500298PA (en) *	2010-01-15	2015-03-30	Gilead Sciences Inc	Inhibitors of flaviviridae viruses
CA2822037A1 (en)	2010-12-20	2012-06-28	Gilead Sciences, Inc.	Methods for treating hcv
DE102011003295A1 (de) *	2011-01-28	2012-08-02	Kiekert Ag	Kraftfahrzeugschloss
WO2013010112A1 (en) *	2011-07-13	2013-01-17	Gilead Sciences, Inc.	Thiophen-2-carboxylic acid derivatives useful as inhibitors of flaviviridae viruses
HUE036588T2 (hu) *	2011-09-16	2018-07-30	Gilead Pharmasset Llc	Eljárások HCV kezelésére
CN103087052A (zh) *	2011-10-31	2013-05-08	上海壹志医药科技有限公司	噻吩衍生物及其药物用途
AR091279A1 (es)	2012-06-08	2015-01-21	Gilead Sciences Inc	Inhibidores macrociclicos de virus flaviviridae
ES2656087T3 (es)	2012-06-08	2018-02-23	Gilead Sciences, Inc.	Inhibidores macrocíclicos de virus Flaviviridae
CN104703991B (zh) *	2012-06-08	2018-03-23	吉利德科学公司	黄病毒科病毒的大环抑制剂
US8927741B2 (en)	2012-08-17	2015-01-06	Gilead Sciences, Inc.	Synthesis of an antiviral compound
US8759544B2 (en)	2012-08-17	2014-06-24	Gilead Sciences, Inc.	Synthesis of an antiviral compound
US8841340B2 (en) *	2012-08-17	2014-09-23	Gilead Sciences, Inc.	Solid forms of an antiviral compound
BR112014011938B1 (pt)	2013-01-31	2021-03-16	Gilead Pharmasset Llc	composição farmacêutica na forma de um comprimido com uma combinação de dose fixa de dois compostos antivirais, forma de dosagem farmacêutica compreendendo a referida composição e uso da referida composição
CN107074904B (zh)	2014-10-23	2022-12-23	深圳华大智造科技股份有限公司	信号约束测序(scs)和用于信号约束测序的核苷酸类似物
CN118286245A (zh)	2014-12-26	2024-07-05	埃莫里大学	N4-羟基胞苷和衍生物及与其相关的抗病毒用途
WO2017192599A1 (en) *	2016-05-02	2017-11-09	Florida State University Research Foundation, Inc.	Treatment of zika virus infections using alpha-glucosidase inhibitors
EP3455219A4 (en)	2016-05-10	2019-12-18	C4 Therapeutics, Inc.	AMINE-RELATED C3-GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION
EP3454862B1 (en)	2016-05-10	2024-09-11	C4 Therapeutics, Inc.	Spirocyclic degronimers for target protein degradation
EP4491236A3 (en)	2016-05-10	2025-04-02	C4 Therapeutics, Inc.	Heterocyclic degronimers for target protein degradation
EP3455218A4 (en)	2016-05-10	2019-12-18	C4 Therapeutics, Inc.	C3 CARBON-BASED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION
ES2912035T3 (es)	2016-06-01	2022-05-24	Athira Pharma Inc	Compuestos
AU2018378832B9 (en)	2017-12-07	2021-05-27	Emory University	N4-hydroxycytidine and derivatives and anti-viral uses related thereto
CN108096562B (zh) *	2017-12-25	2021-05-11	武汉百药联科科技有限公司	20s蛋白酶体抑制剂在制备治疗日本乙型脑炎病毒感染的药物中的用途
US11351149B2 (en)	2020-09-03	2022-06-07	Pfizer Inc.	Nitrile-containing antiviral compounds

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2011
- 2011-01-14 SG SG10201500298PA patent/SG10201500298PA/en unknown
- 2011-01-14 NZ NZ600817A patent/NZ600817A/en not_active IP Right Cessation
- 2011-01-14 KR KR1020127021314A patent/KR101727776B1/ko active Active
- 2011-01-14 CN CN201180005975.8A patent/CN102712633B/zh active Active
- 2011-01-14 JP JP2012549122A patent/JP5868872B2/ja active Active
- 2011-01-14 AP AP2012006414A patent/AP3576A/xx active
- 2011-01-14 PE PE2012000999A patent/PE20130281A1/es not_active Application Discontinuation
- 2011-01-14 EP EP17160365.7A patent/EP3219713A1/en not_active Withdrawn
- 2011-01-14 US US13/007,150 patent/US8513298B2/en active Active
- 2011-01-14 PT PT117009886T patent/PT2523950T/pt unknown
- 2011-01-14 SI SI201131169A patent/SI2523950T1/sl unknown
- 2011-01-14 AR ARP110100126A patent/AR080001A1/es unknown
- 2011-01-14 UY UY0001033183A patent/UY33183A/es not_active Application Discontinuation
- 2011-01-14 AU AU2011205744A patent/AU2011205744B2/en active Active
- 2011-01-14 MX MX2012008211A patent/MX2012008211A/es active IP Right Grant
- 2011-01-14 SG SG2012051181A patent/SG182475A1/en unknown
- 2011-01-14 BR BR112012017382A patent/BR112012017382A2/pt not_active Application Discontinuation
- 2011-01-14 EP EP11700988.6A patent/EP2523950B1/en active Active
- 2011-01-14 TW TW100101437A patent/TWI491609B/zh active
- 2011-01-14 PL PL11700988T patent/PL2523950T3/pl unknown
- 2011-01-14 ES ES11700988.6T patent/ES2626150T3/es active Active
- 2011-01-14 EA EA201290576A patent/EA021196B1/ru not_active IP Right Cessation
- 2011-01-14 CA CA2785567A patent/CA2785567C/en active Active
- 2011-01-14 WO PCT/US2011/021335 patent/WO2011088345A1/en active Application Filing
2012
- 2012-06-21 IL IL220545A patent/IL220545B/en not_active IP Right Cessation
- 2012-07-13 ZA ZA2012/05248A patent/ZA201205248B/en unknown
- 2012-07-13 CL CL2012001960A patent/CL2012001960A1/es unknown
- 2012-08-10 CR CR20120417A patent/CR20120417A/es unknown
- 2012-08-13 EC ECSP12012104 patent/ECSP12012104A/es unknown
2013
- 2013-07-11 US US13/939,695 patent/US9321753B2/en active Active
2015
- 2015-11-02 JP JP2015215450A patent/JP2016041732A/ja not_active Withdrawn

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2008058393A1 (en) *	2006-11-15	2008-05-22	Virochem Pharma Inc.	Thiophene analogues for the treatment or prevention of flavivirus infections

Also Published As

Publication number	Publication date
PT2523950T (pt)	2017-06-01
SG182475A1 (en)	2012-08-30
EA201290576A1 (ru)	2013-01-30
UY33183A (es)	2011-08-31
JP2016041732A (ja)	2016-03-31
PE20130281A1 (es)	2013-03-08
AR080001A1 (es)	2012-03-07
CN102712633A (zh)	2012-10-03
ES2626150T3 (es)	2017-07-24
BR112012017382A2 (pt)	2017-12-05
ZA201205248B (en)	2013-03-27
EP2523950B1 (en)	2017-03-15
TWI491609B (zh)	2015-07-11
CN102712633B (zh)	2015-07-29
MX2012008211A (es)	2012-08-08
NZ600817A (en)	2014-08-29
WO2011088345A1 (en)	2011-07-21
CR20120417A (es)	2012-11-30
US9321753B2 (en)	2016-04-26
CA2785567A1 (en)	2011-07-21
KR101727776B1 (ko)	2017-04-17
US8513298B2 (en)	2013-08-20
EA021196B1 (ru)	2015-04-30
AU2011205744A1 (en)	2012-07-26
IL220545B (en)	2018-02-28
PL2523950T3 (pl)	2017-09-29
IL220545A0 (en)	2012-08-30
US20130315861A1 (en)	2013-11-28
JP2013517291A (ja)	2013-05-16
EP3219713A1 (en)	2017-09-20
KR20120101733A (ko)	2012-09-14
EP2523950A1 (en)	2012-11-21
CA2785567C (en)	2018-03-27
CL2012001960A1 (es)	2012-10-26
US20110178129A1 (en)	2011-07-21
TW201134822A (en)	2011-10-16
JP5868872B2 (ja)	2016-02-24
SG10201500298PA (en)	2015-03-30
AU2011205744B2 (en)	2015-06-25
AP2012006414A0 (en)	2012-08-31
ECSP12012104A (es)	2012-09-28
SI2523950T1 (sl)	2017-06-30

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