OA06811A - Procédé de préparation de nouveaux dérivés de pyridoxine. - Google Patents

Procédé de préparation de nouveaux dérivés de pyridoxine.

Info

Publication number: OA06811A
Authority: OA; OAPI
Prior art keywords: preparation; pyridoxine derivatives; new; new pyridoxine; derivatives
Prior art date: 1980-05-19

Application number

OA57404A

Other languages

English (en)

French (fr)

Inventor

Marcel Urbain

Marcel Descamps

Original Assignee

Labaz Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-05-19

Filing date

1981-05-18

Publication date

1982-12-31

1981-05-18 Application filed by Labaz Nv filed Critical Labaz Nv

1982-12-31 Publication of OA06811A publication Critical patent/OA06811A/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

OA57404A 1980-05-19 1981-05-18 Procédé de préparation de nouveaux dérivés de pyridoxine. OA06811A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8016516		1980-05-19

Publications (1)

Publication Number	Publication Date
OA06811A true OA06811A (fr)	1982-12-31

Family

ID=10513518

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA57404A OA06811A (fr)	1980-05-19	1981-05-18	Procédé de préparation de nouveaux dérivés de pyridoxine.

Country Status (32)

Country	Link
US (1)	US4374841A (xx)
EP (1)	EP0040591B1 (xx)
JP (1)	JPS5711966A (xx)
AR (1)	AR226356A1 (xx)
AT (1)	ATE3859T1 (xx)
AU (1)	AU542463B2 (xx)
BG (1)	BG35327A3 (xx)
CA (1)	CA1152080A (xx)
CS (1)	CS223842B2 (xx)
DD (1)	DD159071A5 (xx)
DE (1)	DE3160480D1 (xx)
DK (1)	DK217481A (xx)
EG (1)	EG15890A (xx)
ES (1)	ES8203845A1 (xx)
FI (1)	FI811525L (xx)
GR (1)	GR82343B (xx)
HU (1)	HU183441B (xx)
IE (1)	IE51179B1 (xx)
IL (1)	IL62602A (xx)
IN (1)	IN151915B (xx)
IS (1)	IS1183B6 (xx)
MA (1)	MA19147A1 (xx)
NO (1)	NO811680L (xx)
NZ (1)	NZ196766A (xx)
OA (1)	OA06811A (xx)
PL (1)	PL129213B1 (xx)
PT (1)	PT72992B (xx)
RO (1)	RO81943A (xx)
SU (1)	SU1077566A3 (xx)
YU (1)	YU126281A (xx)
ZA (1)	ZA812448B (xx)
ZW (1)	ZW9681A1 (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4663354A (en) *	1984-04-26	1987-05-05	Klinge Pharma Gmbh	Use of etilefrin and etilefrin pivalate in the long term treatment of circulatory disorders not due to hypotonia
DE3519693A1 (de) *	1985-06-01	1987-01-02	Basf Ag	Pyridin-derivate, ihre herstellung und verwendung
US6051587A (en) *	1998-04-16	2000-04-18	Medicure, Inc.	Treatment of iatrogenic and age-related hypertension and pharmaceutical compositions useful therein
US6043259A (en) *	1998-07-09	2000-03-28	Medicure Inc.	Treatment of cardiovascular and related pathologies
JP2002539127A (ja)	1999-03-08	2002-11-19	メディキュアインコーポレーテッド	ビタミンｂ−６障害のためのピリドキサル類縁体
US6489345B1 (en)	1999-07-13	2002-12-03	Medicure, Inc.	Treatment of diabetes and related pathologies
JP2003507418A (ja) *	1999-08-24	2003-02-25	メディキュアインターナショナルインコーポレイテッド	心血管疾患とその関連疾患の治療
US7442689B2 (en) *	2000-02-29	2008-10-28	Medicure International Inc.	Cardioprotective phosphonates and malonates
WO2001064692A1 (en)	2000-02-29	2001-09-07	Medicure International Inc.	Cardioprotective phosphonates and malonates
JP2003528146A (ja)	2000-03-28	2003-09-24	メディキュアインターナショナルインコーポレイテッド	脳血管疾患の治療
JP2004502757A (ja)	2000-07-07	2004-01-29	メディキュア　インターナショナル　インコーポレイテッド	ピリドキシンおよびピリドキサール類縁体：心血管系治療薬
US6548519B1 (en)	2001-07-06	2003-04-15	Medicure International Inc.	Pyridoxine and pyridoxal analogues: novel uses
US6897228B2 (en) *	2000-07-07	2005-05-24	Medicure International Inc.	Pyridoxine and pyridoxal analogues: new uses
US20040121988A1 (en) *	2001-03-28	2004-06-24	Medicure International Inc.	Treatment of cerebrovascular disease
JP4048166B2 (ja) *	2002-11-18	2008-02-13	三井製糖株式会社	血糖値上昇抑制剤及び体脂肪蓄積抑制剤並びに食用材料
US20040186077A1 (en) *	2003-03-17	2004-09-23	Medicure International Inc.	Novel heteroaryl phosphonates as cardioprotective agents
EP1608379A1 (en) *	2003-03-27	2005-12-28	Medicure Inc.	Compositions for treating angina
CN101014357A (zh) *	2004-07-07	2007-08-08	麦迪库瑞国际公司	利用血小板聚集药物的组合疗法
US20070060549A1 (en) *	2004-08-10	2007-03-15	Friesen Albert D	Combination therapies employing ace inhibitors and uses thereof for the treatment of diabetic disorders
US20060094749A1 (en) *	2004-10-28	2006-05-04	Medicure International Inc.	Substituted pyridoxines as anti-platelet agents
US7459468B2 (en) *	2004-10-28	2008-12-02	Medicure International, Inc.	Aryl sulfonic pyridoxines as antiplatelet agents
AU2005304220A1 (en) *	2004-10-28	2006-05-18	Medicure International Inc.	Dual antiplatelet/anticoagulant pyridoxine analogs
US20070149485A1 (en) *	2005-11-28	2007-06-28	Medicure International, Inc.	Selected dosage for the treatment of cardiovascular and related pathologies

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR207133A1 (es) *	1973-02-20	1976-09-15	Ciba Geigy Ag	Procedimiento para la elaboracion de derivados de 1-piridiloxi 1-pirimidiniloxi y 1-piraziniloxi-2-hidroxi-3-amino-propano
US4115575A (en) *	1973-02-20	1978-09-19	Ciba-Geigy Corporation	2-(3-Amino-2-hydroxy-propoxy)-pyrazines
GB1485919A (en) *	1975-08-12	1977-09-14	Grindstedvaerket As	Pyridine derivatives
DE2711655A1 (de) *	1977-03-17	1978-09-21	Basf Ag	Pyridinyl-aminoalkylaether
US4210653A (en) *	1978-06-27	1980-07-01	Merck & Co., Inc.	Pyridyloxypropanolamines

1981
- 1981-04-07 IL IL62602A patent/IL62602A/xx unknown
- 1981-04-08 NZ NZ196766A patent/NZ196766A/en unknown
- 1981-04-10 IS IS2631A patent/IS1183B6/is unknown
- 1981-04-13 ZA ZA00812448A patent/ZA812448B/xx unknown
- 1981-04-14 GR GR64686A patent/GR82343B/el unknown
- 1981-04-27 ZW ZW96/81A patent/ZW9681A1/xx unknown
- 1981-04-28 BG BG051875A patent/BG35327A3/xx unknown
- 1981-05-02 IN IN465/CAL/81A patent/IN151915B/en unknown
- 1981-05-07 PT PT72992A patent/PT72992B/pt unknown
- 1981-05-07 AR AR285225A patent/AR226356A1/es active
- 1981-05-11 US US06/262,449 patent/US4374841A/en not_active Expired - Fee Related
- 1981-05-12 EG EG260/81A patent/EG15890A/xx active
- 1981-05-13 AU AU70535/81A patent/AU542463B2/en not_active Ceased
- 1981-05-13 MA MA19356A patent/MA19147A1/fr unknown
- 1981-05-15 DE DE8181870023T patent/DE3160480D1/de not_active Expired
- 1981-05-15 PL PL1981231193A patent/PL129213B1/pl unknown
- 1981-05-15 IE IE1085/81A patent/IE51179B1/en unknown
- 1981-05-15 AT AT81870023T patent/ATE3859T1/de not_active IP Right Cessation
- 1981-05-15 YU YU01262/81A patent/YU126281A/xx unknown
- 1981-05-15 CS CS813634A patent/CS223842B2/cs unknown
- 1981-05-15 JP JP7407681A patent/JPS5711966A/ja active Pending
- 1981-05-15 CA CA000377739A patent/CA1152080A/en not_active Expired
- 1981-05-15 EP EP81870023A patent/EP0040591B1/fr not_active Expired
- 1981-05-18 SU SU813289800A patent/SU1077566A3/ru active
- 1981-05-18 DD DD81230039A patent/DD159071A5/de unknown
- 1981-05-18 RO RO81104319A patent/RO81943A/ro unknown
- 1981-05-18 FI FI811525A patent/FI811525L/fi not_active Application Discontinuation
- 1981-05-18 NO NO811680A patent/NO811680L/no unknown
- 1981-05-18 ES ES502276A patent/ES8203845A1/es not_active Expired
- 1981-05-18 OA OA57404A patent/OA06811A/xx unknown
- 1981-05-18 HU HU811402A patent/HU183441B/hu unknown
- 1981-05-18 DK DK217481A patent/DK217481A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
ES502276A0 (es)	1982-04-01
ES8203845A1 (es)	1982-04-01
EP0040591A1 (fr)	1981-11-25
FI811525L (fi)	1981-11-20
AU542463B2 (en)	1985-02-21
SU1077566A3 (ru)	1984-02-29
CS223842B2 (en)	1983-11-25
EG15890A (en)	1987-03-30
EP0040591B1 (fr)	1983-06-22
MA19147A1 (fr)	1981-12-31
PL231193A1 (xx)	1982-07-05
CA1152080A (en)	1983-08-16
NO811680L (no)	1981-11-20
GR82343B (xx)	1984-12-13
JPS5711966A (en)	1982-01-21
RO81943A (ro)	1983-06-01
ATE3859T1 (de)	1983-07-15
HU183441B (en)	1984-05-28
RO81943B (ro)	1983-05-30
DD159071A5 (de)	1983-02-16
DK217481A (da)	1981-11-20
IN151915B (xx)	1983-09-03
DE3160480D1 (en)	1983-07-28
AU7053581A (en)	1981-11-26
NZ196766A (en)	1984-02-03
US4374841A (en)	1983-02-22
YU126281A (en)	1984-02-29
BG35327A3 (en)	1984-03-15
PT72992A (en)	1981-06-01
PL129213B1 (en)	1984-04-30
IE811085L (en)	1981-11-19
AR226356A1 (es)	1982-06-30
IL62602A (en)	1984-06-29
ZA812448B (en)	1982-04-28
ZW9681A1 (en)	1982-01-20
IS1183B6 (is)	1985-05-13
IL62602A0 (en)	1981-06-29
PT72992B (en)	1982-07-01
IE51179B1 (en)	1986-10-29
IS2631A7 (is)	1981-11-11

Publication	Publication Date	Title
OA06811A (fr)	1982-12-31	Procédé de préparation de nouveaux dérivés de pyridoxine.
OA06914A (fr)	1983-05-31	Procédé de préparation d'iminodiacides substitués.
OA07766A (fr)	1985-08-30	Procédé de préparation de dérivés de cephème.
OA05928A (fr)	1981-06-30	Nouveaux dérivés de céphalosporine, leur procédé de préparation.
DZ418A1 (fr)	2004-09-13	Dérivés de céphalosporine, leur procédé de préparation et leur application thérapeutique.
OA05444A (fr)	1981-03-31	Procédé de préparation de nouveaux dérivés benzhydrylsulfinyle.
OA07003A (fr)	1983-08-31	Préparation de nouveaux dérivés de la furo-(3,4-c) -pyridine.
OA04687A (fr)	1980-07-31	Procédé de préparation de nouveaux dérivés de l'indole.
OA06563A (fr)	1981-07-31	Procédé de préparation de nouveaux dérivés d'indolizine.
OA05725A (fr)	1981-05-31	Procédé de préparation de dérivés d'acides hydroxy-aminophosphonique hydrocarbonés.
OA06951A (fr)	1983-07-31	Dérivés de la thiéno-pyridinone, leur procédé de préparation et leur application thérapeutique.
OA06486A (fr)	1981-07-31	Procédé de préparation de 9 aminoalkylfluorènes.
OA05385A (fr)	1981-02-28	Procédé de préparation de nouveaux dérivés phénoxy.
OA07674A (fr)	1985-05-23	Procédé de préparation de dérivés de carbapénem, nouveaux intermédiaires de synthèse et préparation de ces intermédiaires.
OA06356A (fr)	1981-06-30	Procédé de préparation de 2-chlorosulfinylazétidinones.
OA05260A (fr)	1981-02-28	Procédé de préparation de dérivés d'histidine.
OA05485A (fr)	1981-03-31	Procédé de préparation de nouveaux dérivés hétérocycliques.
OA06274A (fr)	1981-06-30	Procédé de préparation de nouveaux composés de type muramyl-péptide.
EP0092948A2 (en)	1983-11-02	Penicillin derivatives and process for preparation of the same.
OA06258A (fr)	1981-06-30	Procédé de préparation de nouveaux dérivés acétyléniques de l'androst-4-ène.
OA06355A (fr)	1981-06-30	Procédé de préparation de 3-exométhylènecépham-sulfoxydes.
DZ687A1 (fr)	2004-09-13	Dérivés de la chlori-4-furo-(3,4-c)-pyridine et leur procédé de préparation.
OA05778A (fr)	1981-05-31	Procédé de préparation de dérivés l-(N-acylcarbamoyl) 2-cyano-aziridines.
OA07833A (fr)	1986-11-20	Procédé de préparation de nouveaux dérivés de 1-(acétylamino)-2-amino-propanone.
OA06879A (fr)	1983-02-28	Procédé de préparation de dérivés d'hétéroprostaglandines.