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NZ609247A - Preservative system for emulsion-based therapeutic topical formulations - Google Patents

Preservative system for emulsion-based therapeutic topical formulations

Info

Publication number
NZ609247A
NZ609247A NZ609247A NZ60924709A NZ609247A NZ 609247 A NZ609247 A NZ 609247A NZ 609247 A NZ609247 A NZ 609247A NZ 60924709 A NZ60924709 A NZ 60924709A NZ 609247 A NZ609247 A NZ 609247A
Authority
NZ
New Zealand
Prior art keywords
alcohol
formulation
growth
aqueous phase
microorganisms
Prior art date
Application number
NZ609247A
Inventor
Nicholas Spring
Edward J Delaney
Original Assignee
Sanofi Topaz Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Topaz Inc filed Critical Sanofi Topaz Inc
Priority to NZ700972A priority Critical patent/NZ700972A/en
Publication of NZ609247A publication Critical patent/NZ609247A/en

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The disclosure relates to a topical formulation for treating a lice infestation, comprising an effective amount of an avermectin insecticide dissolved in an oil phase and an aqueous phase comprising one or more preservatives to inhibit the growth of microorganisms. Olive oil is present at a level of about 20% to about 30% by weight of the formulation, and the aqueous phase is buffered with a buffer comprising citric acid and/or sodium citrate to a pH that is from about 4.5 to about 6.2. The oil phase comprises a water-miscible or water-soluble surface active agent, which may comprise polysorbate 80, cetyl acetate, and acetylated lanolin alcohol, olive oil and shea butter as suspending agents, and a non-ionic surfactant selected from the group consisting of: oleyl alcohol, lanolin alcohol, sorbitan tristearate, bees wax, erucyl alcohol, ricinolyl alcohol, arachidyl alcohol, capryl alcohol, capric alcohol, behenyl alcohol, lauryl alcohol, myristyl alcohol, cetyl alcohol, stearyl alcohol, isostearyl alcohol, oleyl alcohol, palmitoleyl alcohol, linoleyl alcohol, elaidyl alcohol, elaidolinoleyl alcohol, linolenyl alcohol, elaidolinolenyl alcohol and combinations thereof. The formulation may exhibit an enhancedresistance to growth of one or more microorganisms selected from the group consisting of Candida albicans, Aspergillus niger, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus.
NZ609247A 2008-10-29 2009-10-29 Preservative system for emulsion-based therapeutic topical formulations NZ609247A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ700972A NZ700972A (en) 2008-10-29 2009-10-29 Preservative system for emulsion-based therapeutic topical formulations

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10932508P 2008-10-29 2008-10-29
NZ59248209 2009-10-29

Publications (1)

Publication Number Publication Date
NZ609247A true NZ609247A (en) 2014-10-31

Family

ID=51796545

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ609247A NZ609247A (en) 2008-10-29 2009-10-29 Preservative system for emulsion-based therapeutic topical formulations

Country Status (1)

Country Link
NZ (1) NZ609247A (en)

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Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 29 OCT 2016 BY AJ PARK

Effective date: 20150528

LAPS Patent lapsed