NO903832L - Amino acid derivative. - Google Patents

Amino acid derivative.

Info

Publication number: NO903832L
Authority: NO; Norway
Prior art keywords: amino acid; acid derivative; derivative; amino; acid
Prior art date: 1989-09-04

Application number

NO90903832A

Other languages

Norwegian (no)

Other versions

NO903832D0 (en

Inventor

Quirico Branca

Werner Neidhart

Henri Ramuz

Heinz Stadler

Wolfgang Wostl

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-09-04

Filing date

1990-09-03

Publication date

1991-03-05

1990-09-03 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

1990-09-03 Publication of NO903832D0 publication Critical patent/NO903832D0/en

1991-03-05 Publication of NO903832L publication Critical patent/NO903832L/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/23—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
- C07C311/25—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pyrrole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Peptides Or Proteins (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO90903832A 1989-09-04 1990-09-03 Amino acid derivative. NO903832L (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
CH319289		1989-09-04
CH233690		1990-07-12

Publications (2)

Publication Number	Publication Date
NO903832D0 NO903832D0 (en)	1990-09-03
NO903832L true NO903832L (en)	1991-03-05

Family

ID=25690187

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO90903832A NO903832L (en)	1989-09-04	1990-09-03	Amino acid derivative.

Country Status (14)

Country	Link
US (1)	US5688946A (en)
EP (1)	EP0416373A3 (en)
JP (1)	JPH0399047A (en)
KR (1)	KR910006224A (en)
AU (1)	AU646640B2 (en)
CA (1)	CA2023099A1 (en)
FI (1)	FI904360A0 (en)
HU (1)	HUT58060A (en)
IE (1)	IE903197A1 (en)
IL (1)	IL95503A0 (en)
MC (1)	MC2151A1 (en)
NO (1)	NO903832L (en)
NZ (1)	NZ235057A (en)
PT (1)	PT95192A (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE68045B1 (en) *	1990-05-11	1996-05-15	Abbott Lab	Renin inhibitors
US5275950A (en) *	1990-05-11	1994-01-04	Abbott Laboratories	Process for the preparation of a renin inhibiting compound
US5278161A (en) *	1990-06-28	1994-01-11	Hoffmann-La Roche Inc.	Amino acid derivatives useful as renin inhibitors
DE4040056A1 (en) *	1990-12-14	1992-06-17	Merck Patent Gmbh	acid amides
TW198712B (en) *	1991-04-17	1993-01-21	Hoffmann La Roche
US5268361A (en) *	1991-06-07	1993-12-07	Sri International	Hydroxyazido derivatives and related compounds as renin inhibitors
CA2095671A1 (en) *	1992-06-04	1993-12-05	Quirico Branca	Amino acid derivatives
US5317039A (en) *	1992-07-20	1994-05-31	G. D. Searle & Co.	Cyclopropyl-alanine aryl/alkylsulfide/sulfonyl-terminated amino-diol compounds for treatment of hypertension
US5559256A (en) *	1992-07-20	1996-09-24	E. R. Squibb & Sons, Inc.	Aminediol protease inhibitors
US5268391A (en) *	1992-07-20	1993-12-07	C. D. Searle & Co.	Propargyl-terminated cycloalkylalkyl-P2-site substituted aryl/alkylsulfonyl-terminated alanine amino-diol compounds for treatment of hypertension
US5246969A (en) *	1992-07-20	1993-09-21	G. D. Searle & Co.	Di-propargyl-containing aryl/alkylsulfonyl-terminated alanine amino-diol compounds for treatment of hypertension
US5314920A (en) *	1992-07-20	1994-05-24	G. D. Searle & Co.	Ethynyl-alanine aryl/alkylsulfonyl-terminated amino-diol compounds for treatment of hypertension
US5212185A (en) *	1992-08-14	1993-05-18	G. D. Searle & Co.	Piperidinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension
US5312838A (en) *	1992-09-21	1994-05-17	G. D. Searle & Co.	β-alanineamide aryl/alkylsulfide/sulfonyl-terminated amino-diol compounds for treatment of hypertension
ES2100109B1 (en) *	1993-07-14	1998-02-16	Squibb & Sons Inc	AMINODIOL PROTEASE INHIBITORS.
US5414018A (en) *	1993-09-24	1995-05-09	G. D. Searle & Co.	Alkylaminoalkyl-terminated sulfide/sulfonyl-containing propargyl amino-diol compounds for treatment of hypertension
US5416119A (en) *	1993-10-25	1995-05-16	G. D. Searle & Co.	Alkylaminoalkyl-terminated sulfide/sulfonyl-containing cycloalkyl-alanine amino-diol compounds for treatment of hypertension
US5432201A (en) *	1993-11-22	1995-07-11	G. D. Searle & Co.	Alkylaminoalkyl-sulfonyl-terminated β-alanineamide amino-diol compounds for treatment of hypertension
PL346762A1 (en) *	1998-07-06	2002-02-25	Guilford Pharm Inc	Naaladase inhibitors useful as pharmaceutical compounds and compositions
WO2000051998A1 (en) *	1999-03-02	2000-09-08	Boehringer Ingelheim Pharmaceuticals, Inc.	Compounds useful as reversible inhibitors of cathepsin s
JP2002201168A (en) *	2000-12-28	2002-07-16	Kaken Pharmaceut Co Ltd	Cyclohexane derivative
AU2002251913A1 (en) *	2001-02-02	2002-08-19	Millennium Pharmaceuticals, Inc.	Hybrid antibodies and uses thereof
US6818787B2 (en)	2001-06-11	2004-11-16	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en)	2001-06-11	2007-06-19	Xenoport, Inc.	Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US7186855B2 (en)	2001-06-11	2007-03-06	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en)	2005-04-06	2011-11-01	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
UA108742C2 (en)	2009-09-23	2015-06-10		PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF MCP-1 MEDIATED DISEASES
EP3052474A1 (en) *	2013-10-04	2016-08-10	Solvay Specialty Polymers Italy S.p.A.	Process for the synthesis of fluoralkyl sulfonate salts
KR20190068537A (en) *	2016-09-18	2019-06-18	에이치 리 모피트 캔서 센터 앤드 리서어치 인스티튜트 아이엔씨	YAP1 inhibitors that target the interaction of YAP1 and OCT4

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4652551A (en) *	1984-06-22	1987-03-24	Abbott Laboratories	Renin inhibiting compounds
US4845079A (en) *	1985-01-23	1989-07-04	Luly Jay R	Peptidylaminodiols
EP0258289A4 (en) *	1986-01-16	1991-01-02	Joseph Dellaria	Peptide analogs
NZ218937A (en) *	1986-01-16	1990-03-27	Abbott Lab	Functionalised peptidyl aminodiols and -triols as renin inhibitors and pharmaceutical compositions
US4726941A (en) *	1986-01-23	1988-02-23	Regents Of The University Of Minnesota	Acylated cyanamide composition for treating ethanol ingestion
US5032577A (en) *	1986-12-31	1991-07-16	Abbott Laboratories	Peptidylaminodiols
ATE165085T1 (en) *	1987-09-29	1998-05-15	Banyu Pharma Co Ltd	N-ACYLAMINOSIC ACID DERIVATIVES AND USE THEREOF
EP0313847A3 (en) *	1987-10-01	1989-11-29	G.D. Searle & Co.	Non-peptidyl alpha-succinamidoacyl aminodiols as anti-hypertensive agents
CA1328333C (en) *	1988-03-04	1994-04-05	Quirico Branca	Amino acid derivatives
TW225540B (en) *	1990-06-28	1994-06-21	Shionogi & Co
AU8478191A (en) *	1990-09-27	1992-04-02	Merk & Co., Inc.	Fibrinogen receptor antagonists

1990
- 1990-08-10 CA CA002023099A patent/CA2023099A1/en not_active Abandoned
- 1990-08-22 EP EP19900116088 patent/EP0416373A3/en not_active Withdrawn
- 1990-08-27 NZ NZ235057A patent/NZ235057A/en unknown
- 1990-08-27 AU AU61360/90A patent/AU646640B2/en not_active Ceased
- 1990-08-28 IL IL95503A patent/IL95503A0/en unknown
- 1990-08-29 HU HU905676A patent/HUT58060A/en unknown
- 1990-08-30 MC MC902146A patent/MC2151A1/en unknown
- 1990-08-31 JP JP2228473A patent/JPH0399047A/en active Pending
- 1990-09-03 IE IE319790A patent/IE903197A1/en unknown
- 1990-09-03 PT PT95192A patent/PT95192A/en not_active Application Discontinuation
- 1990-09-03 NO NO90903832A patent/NO903832L/en unknown
- 1990-09-04 KR KR1019900013893A patent/KR910006224A/en not_active Application Discontinuation
- 1990-09-04 FI FI904360A patent/FI904360A0/en not_active IP Right Cessation
1994
- 1994-07-19 US US08/277,111 patent/US5688946A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
US5688946A (en)	1997-11-18
IE903197A1 (en)	1991-03-13
HUT58060A (en)	1992-01-28
FI904360A0 (en)	1990-09-04
JPH0399047A (en)	1991-04-24
PT95192A (en)	1991-05-22
NO903832D0 (en)	1990-09-03
CA2023099A1 (en)	1991-03-05
KR910006224A (en)	1991-04-27
AU646640B2 (en)	1994-03-03
NZ235057A (en)	1994-12-22
MC2151A1 (en)	1992-03-10
EP0416373A2 (en)	1991-03-13
HU905676D0 (en)	1991-03-28
EP0416373A3 (en)	1992-05-27
IL95503A0 (en)	1991-06-30
AU6136090A (en)	1991-03-07

Publication	Publication Date	Title
NO901399D0 (en)	1990-03-27	Amino acid derivative.
NO892407D0 (en)	1989-06-12	Amino acid derivative.
NO901033L (en)	1990-09-07	Amino acid derivative.
NO903832D0 (en)	1990-09-03	Amino acid derivative.
DE59008394D1 (en)	1995-03-16	Amino acid amide derivatives.
NO920417D0 (en)	1992-01-31	amino acid derivative
DE69014865D1 (en)	1995-01-19	PEROXYCARBOXYLIC ACID.
DK340088D0 (en)	1988-06-21	AMINO ACID DERIVATIVES
DK96889A (en)	1989-09-05	AMINO ACID DERIVATIVES
DE122005000012I1 (en)	2005-06-23	N- (pyrrolo (2-3-d) pyrimidin-3-ylacyl) {-Glutamins acid derivatives.
NO884434D0 (en)	1988-10-05	Amino acid derivative.
DE3787657D1 (en)	1993-11-11	Amino acid derivatives.
NO901533D0 (en)	1990-04-04	Amino acid derivative.
NO912537L (en)	1991-12-30	Amino acid derivative.
NO890635D0 (en)	1989-02-15	PURIFICANT AMINO ACID DERIVATIVES.
NO900025D0 (en)	1990-01-04	PYRROLYLPHENYL-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES.
DK10190A (en)	1990-01-15	1,1-DIOXO-CEPHEM-4-CARBOTHIOLIC ACID DERIVATIVES
NO892728D0 (en)	1989-06-30	AMINOALKYL-AMINOCARBONYL-AMINODIOLAMINO ACID DERIVATIVES SOMANTI-HYPERTENSIVE AGENTS.
DE69018816D1 (en)	1995-05-24	AMINO ACID DERIVATIVES.
NO901519L (en)	1990-10-05	Amino acid derivative.
DE59002430D1 (en)	1993-09-30	Cyclopropanoylamino acid amide derivatives.
NO924423D0 (en)	1992-11-17	amino acid derivative
ATE105549T1 (en)	1994-05-15	AMINO ACID DERIVATIVES.
ATE95518T1 (en)	1993-10-15	AMINO ACID DERIVATIVES.
NO870781L (en)	1987-02-25	Amino acid derivative.