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NO882113D0 - SUBSTITUTED VINYL CEPHALOSPORINES, THE PROCEDURE FOR THEIR PREPARATION, AND THEIR USE AS A MEDICINE. - Google Patents

SUBSTITUTED VINYL CEPHALOSPORINES, THE PROCEDURE FOR THEIR PREPARATION, AND THEIR USE AS A MEDICINE.

Info

Publication number
NO882113D0
NO882113D0 NO882113A NO882113A NO882113D0 NO 882113 D0 NO882113 D0 NO 882113D0 NO 882113 A NO882113 A NO 882113A NO 882113 A NO882113 A NO 882113A NO 882113 D0 NO882113 D0 NO 882113D0
Authority
NO
Norway
Prior art keywords
cephalosporines
medicine
procedure
preparation
substituted vinyl
Prior art date
Application number
NO882113A
Other languages
Norwegian (no)
Other versions
NO882113L (en
NO170936B (en
NO170936C (en
Inventor
Gunter Schmidt
Karl Georg Metzger
Hans-Joachim Zeiler
Rainer Endermann
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO882113D0 publication Critical patent/NO882113D0/en
Publication of NO882113L publication Critical patent/NO882113L/en
Publication of NO170936B publication Critical patent/NO170936B/en
Publication of NO170936C publication Critical patent/NO170936C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/195—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Aiming, Guidance, Guns With A Light Source, Armor, Camouflage, And Targets (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Vinylcephalosporins of the formula (I) <IMAGE> in which the symbols R<1>, R<2>, R<3>, R<4> and R<5> have the meaning given in the description.
NO882113A 1987-05-26 1988-05-13 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE, SUBSTITUTED VINYL Cephalosporins NO170936C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3717663 1987-05-26
DE19873734005 DE3734005A1 (en) 1987-05-26 1987-10-08 SUBSTITUTED VINYLCEPHALOSPORINS, THE METHOD OF MANUFACTURING THEIR PRODUCTS AND THEIR USE AS A MEDICINAL PRODUCT

Publications (4)

Publication Number Publication Date
NO882113D0 true NO882113D0 (en) 1988-05-13
NO882113L NO882113L (en) 1988-11-28
NO170936B NO170936B (en) 1992-09-21
NO170936C NO170936C (en) 1993-01-06

Family

ID=25856023

Family Applications (1)

Application Number Title Priority Date Filing Date
NO882113A NO170936C (en) 1987-05-26 1988-05-13 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE, SUBSTITUTED VINYL Cephalosporins

Country Status (15)

Country Link
EP (1) EP0292806B1 (en)
JP (1) JPH0645628B2 (en)
KR (1) KR880013925A (en)
CN (1) CN1020732C (en)
AT (1) ATE113598T1 (en)
AU (1) AU1630288A (en)
CA (1) CA1340424C (en)
DE (2) DE3734005A1 (en)
DK (1) DK284588A (en)
ES (1) ES2061550T3 (en)
FI (1) FI882444A (en)
HU (1) HU205938B (en)
IL (1) IL86479A (en)
NO (1) NO170936C (en)
PT (1) PT87563B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3734004A1 (en) * 1987-05-26 1988-12-15 Bayer Ag SUBSTITUTED VINYLCEPHALOSPORINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT
DE3933934A1 (en) * 1989-10-03 1991-04-11 Bayer Ag METHOD FOR PRODUCING 7-AMINO-3 - ((Z) -1-PROPEN-1-YL) -3-CEPHEM-4-CARBONIC ACID
PT630380E (en) * 1992-02-05 2002-02-28 Biochemie Gmbh PROCESS FOR THE PURIFICATION OF A DERIVATIVE OF 3-CEFEM-4-CARBOXYLIC ACID
AT399876B (en) * 1992-02-05 1995-08-25 Biochemie Gmbh Purificn. of 7-amino-3-((z)-1-propen-1-yl)-3 -cephem-4-carboxylic acid - useful in prodn. of broadband antibiotics
WO2009049086A1 (en) 2007-10-09 2009-04-16 Larry Sutton Broad spectrum beta-lactamase inhibitors
JP6403289B2 (en) 2013-03-12 2018-10-10 グラディウス ファーマシューティカルズ コーポレーションＧｌａｄｉｕｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｃｏｒｐｏｒａｔｉｏｎ Derivatized 3-styryl-cephalosporin

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3769277A (en) * 1970-01-23 1973-10-30 Glaxo Lab Ltd Preparation of delta3-4 carboxy cephalosporins having a 3-vinyl or substituted 3-vinyl group
US4390693A (en) * 1977-07-27 1983-06-28 Merck & Co., Inc. Cephalosporin compounds
US4255423A (en) * 1977-07-27 1981-03-10 Merck & Co., Inc. Cephalosporin compounds
US4520022A (en) * 1983-01-28 1985-05-28 Bristol-Myers Company Substituted vinyl cephalosporins
DE3508258A1 (en) * 1985-03-08 1986-09-18 Bayer Ag, 5090 Leverkusen SS LACTAMANTIBIOTICS, METHOD FOR THE PRODUCTION AND THEIR USE AS AND IN MEDICINAL PRODUCTS
US4619925A (en) * 1985-11-08 1986-10-28 Bristol-Myers Company 3-Propenyl cephalosporin derivatives
JPS63126022A (en) * 1986-11-17 1988-05-30 Hitachi Ltd Display device
DE3734004A1 (en) * 1987-05-26 1988-12-15 Bayer Ag SUBSTITUTED VINYLCEPHALOSPORINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICINAL PRODUCT

Also Published As

Publication number Publication date
PT87563B (en) 1992-09-30
AU1630288A (en) 1988-12-01
CA1340424C (en) 1999-03-09
HUT48891A (en) 1989-07-28
JPS63307884A (en) 1988-12-15
ATE113598T1 (en) 1994-11-15
DK284588A (en) 1988-11-27
NO882113L (en) 1988-11-28
NO170936B (en) 1992-09-21
FI882444A0 (en) 1988-05-24
ES2061550T3 (en) 1994-12-16
NO170936C (en) 1993-01-06
FI882444A (en) 1988-11-27
JPH0645628B2 (en) 1994-06-15
CN88103111A (en) 1988-12-28
KR880013925A (en) 1988-12-22
EP0292806A2 (en) 1988-11-30
PT87563A (en) 1989-05-31
DE3851979D1 (en) 1994-12-08
HU205938B (en) 1992-07-28
CN1020732C (en) 1993-05-19
DK284588D0 (en) 1988-05-25
DE3734005A1 (en) 1988-12-15
EP0292806A3 (en) 1990-10-17
IL86479A (en) 1993-08-18
IL86479A0 (en) 1988-11-15
EP0292806B1 (en) 1994-11-02

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