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NO880206D0 - 1-((4-morfolinyl)alkyl)-1h-indoler med analgetisk aktivitet og fremgangsmaate for deres fremstilling. - Google Patents

1-((4-morfolinyl)alkyl)-1h-indoler med analgetisk aktivitet og fremgangsmaate for deres fremstilling.

Info

Publication number
NO880206D0
NO880206D0 NO880206A NO880206A NO880206D0 NO 880206 D0 NO880206 D0 NO 880206D0 NO 880206 A NO880206 A NO 880206A NO 880206 A NO880206 A NO 880206A NO 880206 D0 NO880206 D0 NO 880206D0
Authority
NO
Norway
Prior art keywords
indoles
morpholinyl
alkyl
procedure
preparation
Prior art date
Application number
NO880206A
Other languages
English (en)
Other versions
NO169713C (no
NO880206L (no
NO169713B (no
Inventor
Ambra Thomas Edward D
Malcolm Rice Bell
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of NO880206D0 publication Critical patent/NO880206D0/no
Publication of NO880206L publication Critical patent/NO880206L/no
Publication of NO169713B publication Critical patent/NO169713B/no
Publication of NO169713C publication Critical patent/NO169713C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO880206A 1987-02-11 1988-01-19 Analogifremgangsmaate for fremstilling av terapeutisk aktive 4-arylkarbonyl-1-((4-morfolinyl)alkyl)-1h-indoler. NO169713C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/013,313 US4840950A (en) 1987-02-11 1987-02-11 4-arylcarbonyl-1-[(4-morpholinyl)-lower-alkyl]-1H-indoles

Publications (4)

Publication Number Publication Date
NO880206D0 true NO880206D0 (no) 1988-01-19
NO880206L NO880206L (no) 1988-08-12
NO169713B NO169713B (no) 1992-04-21
NO169713C NO169713C (no) 1992-07-29

Family

ID=21759325

Family Applications (1)

Application Number Title Priority Date Filing Date
NO880206A NO169713C (no) 1987-02-11 1988-01-19 Analogifremgangsmaate for fremstilling av terapeutisk aktive 4-arylkarbonyl-1-((4-morfolinyl)alkyl)-1h-indoler.

Country Status (21)

Country Link
US (1) US4840950A (no)
EP (1) EP0278265B1 (no)
JP (1) JP2561939B2 (no)
KR (1) KR960007523B1 (no)
AR (1) AR243184A1 (no)
AT (1) ATE80386T1 (no)
AU (1) AU596494B2 (no)
CA (1) CA1299180C (no)
DE (1) DE3874361T2 (no)
DK (1) DK167921B1 (no)
ES (1) ES2052608T3 (no)
FI (1) FI88152C (no)
GR (1) GR3005855T3 (no)
IE (1) IE63264B1 (no)
IL (1) IL84922A (no)
MX (1) MX174421B (no)
NO (1) NO169713C (no)
NZ (1) NZ223146A (no)
PH (1) PH25902A (no)
PT (1) PT86527B (no)
ZA (1) ZA879723B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5081122A (en) * 1990-03-05 1992-01-14 Sterling Drug Inc. Antiglaucoma compositions containing 4-arylcarbonyl-1-(4-morpholinyl)-lower-alkyl)-1H-indoles and method of use thereof
CA2651732C (en) 2006-05-18 2014-10-14 Mannkind Corporation Intracellular kinase inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3182071A (en) * 1961-06-27 1965-05-04 Warner Lambert Pharmaceutical Acylated indole derivatives
US3215699A (en) * 1961-06-27 1965-11-02 Warner Lambert Pharmaceutical Substituted acetylphenyl hydrazones of 2,3-piperidine diones
US3494920A (en) * 1967-12-18 1970-02-10 American Home Prod 1-di(lower)alkylamino(lower)alkyl-3-(2-substituted ethyl) indoles
GB1374414A (en) * 1972-06-12 1974-11-20 Sterling Drug Inc 1-acyl-3-amino-alkyl-indoles and their preparation
GB1436771A (en) * 1973-02-16 1976-05-26 Labaz Indole derivatives and process for preparing the same
US4581354A (en) * 1984-08-06 1986-04-08 Sterling Drug Inc. 3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use
PH23498A (en) * 1984-08-06 1989-08-16 Sterling Drug Inc 3-carbonyl-1-aminoalkyl-1h-indoles,composition and use thereof

Also Published As

Publication number Publication date
GR3005855T3 (no) 1993-06-07
EP0278265A1 (en) 1988-08-17
JP2561939B2 (ja) 1996-12-11
JPS63216865A (ja) 1988-09-09
PH25902A (en) 1991-12-19
PT86527A (en) 1988-02-01
FI880117A0 (fi) 1988-01-12
IE880047L (en) 1988-08-11
IE63264B1 (en) 1995-04-05
IL84922A (en) 1992-03-29
KR960007523B1 (ko) 1996-06-05
NO169713C (no) 1992-07-29
ES2052608T3 (es) 1994-07-16
DK167921B1 (da) 1994-01-03
AU596494B2 (en) 1990-05-03
DK21588D0 (da) 1988-01-19
ATE80386T1 (de) 1992-09-15
KR880009962A (ko) 1988-10-06
EP0278265B1 (en) 1992-09-09
US4840950A (en) 1989-06-20
NO880206L (no) 1988-08-12
PT86527B (pt) 1991-12-31
DE3874361D1 (de) 1992-10-15
FI88152B (fi) 1992-12-31
MX10085A (es) 1993-09-01
NO169713B (no) 1992-04-21
DK21588A (da) 1988-08-12
DE3874361T2 (de) 1993-03-25
CA1299180C (en) 1992-04-21
FI88152C (fi) 1993-04-13
MX174421B (es) 1994-05-16
ZA879723B (en) 1988-06-23
NZ223146A (en) 1990-01-29
FI880117A (fi) 1988-08-12
IL84922A0 (en) 1988-06-30
AR243184A1 (es) 1993-07-30
AU1038788A (en) 1988-08-18

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Legal Events

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MK1K Patent expired