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NO884671D0 - Nye flourmetoksyfenyldihydropyridiner, fremgangsmaate til deres fremstilling og deres anvendelse i legemidler. - Google Patents

Nye flourmetoksyfenyldihydropyridiner, fremgangsmaate til deres fremstilling og deres anvendelse i legemidler.

Info

Publication number
NO884671D0
NO884671D0 NO884671A NO884671A NO884671D0 NO 884671 D0 NO884671 D0 NO 884671D0 NO 884671 A NO884671 A NO 884671A NO 884671 A NO884671 A NO 884671A NO 884671 D0 NO884671 D0 NO 884671D0
Authority
NO
Norway
Prior art keywords
flourmetoxyphenylnedhydropyridines
pharmaceuticals
procedures
preparation
new
Prior art date
Application number
NO884671A
Other languages
English (en)
Other versions
NO884671L (no
Inventor
Gerhard Franckowiak
Juergen Stoltefuss
Martin Bechem
Reiner Gross
Michael Kayser
Siegbert Habisch
Matthias Schramm
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of NO884671D0 publication Critical patent/NO884671D0/no
Publication of NO884671L publication Critical patent/NO884671L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO88884671A 1987-11-04 1988-10-20 Nye flourmetoksyfenyldihydropyridiner, fremgangsmaate til deres fremstilling og deres anvendelse i legemidler. NO884671L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873737340 DE3737340A1 (de) 1987-11-04 1987-11-04 Neue fluormethoxyphenyl-dihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln

Publications (2)

Publication Number Publication Date
NO884671D0 true NO884671D0 (no) 1988-10-20
NO884671L NO884671L (no) 1989-05-05

Family

ID=6339713

Family Applications (1)

Application Number Title Priority Date Filing Date
NO88884671A NO884671L (no) 1987-11-04 1988-10-20 Nye flourmetoksyfenyldihydropyridiner, fremgangsmaate til deres fremstilling og deres anvendelse i legemidler.

Country Status (15)

Country Link
US (1) US5008279A (no)
EP (1) EP0315018A3 (no)
JP (1) JPH01151555A (no)
KR (1) KR890008097A (no)
CN (1) CN1040192A (no)
AU (1) AU613101B2 (no)
DD (1) DD283380A5 (no)
DE (1) DE3737340A1 (no)
DK (1) DK614088A (no)
FI (1) FI885056A (no)
HU (1) HU201526B (no)
IL (1) IL88237A0 (no)
NO (1) NO884671L (no)
PT (1) PT88920B (no)
ZA (1) ZA888234B (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5137889A (en) * 1983-12-02 1992-08-11 Otsuka Pharmaceutical Co., Ltd. Dihydropyridine derivatives and process for preparing the same
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US5770609A (en) * 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
CA2223595C (en) * 1995-06-07 2008-08-05 Neorx Corporation Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
WO1998046588A2 (en) 1997-04-11 1998-10-22 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
WO1998049144A1 (fr) 1997-04-25 1998-11-05 Ajinomoto Co., Inc. Nouveau derive de dihydropyridine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2752820A1 (de) * 1977-11-26 1979-05-31 Bayer Ag Neue nitrosubstituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4285955A (en) * 1978-10-31 1981-08-25 Bayer Aktiengesellschaft 1,4-Dihydropyridinecarboxylic acids
DE3447169A1 (de) * 1984-12-22 1986-07-03 Bayer Ag, 5090 Leverkusen Optisch aktive nitrodihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln
US4868181A (en) * 1986-08-04 1989-09-19 E. I. Du Pont De Nemours And Company 1,4-dihydropyridine derivatives with calcium agonist and alpha1 -antagonist activity
US4920225A (en) * 1986-12-22 1990-04-24 Laboratoires Syntex S.A. Resolution of 1,4-dihydropyridine derivatives
DE3737341A1 (de) * 1987-11-04 1989-05-18 Bayer Ag Neue fluormethoxyphenyl-dihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln
DE3821334A1 (de) * 1988-06-24 1989-12-28 Bayer Ag 1,4-dihydropyridin-threonin-derivate, verfahren zu ihrer herstellung, zwischenprodukte und ihre verwendung als arzneimittel

Also Published As

Publication number Publication date
DE3737340A1 (de) 1989-05-24
DD283380A5 (de) 1990-10-10
AU2457688A (en) 1989-05-04
PT88920B (pt) 1993-01-29
EP0315018A2 (de) 1989-05-10
PT88920A (pt) 1988-12-01
KR890008097A (ko) 1989-11-26
HU201526B (en) 1990-11-28
FI885056A0 (fi) 1988-11-02
IL88237A0 (en) 1989-06-30
DK614088A (da) 1989-05-05
ZA888234B (en) 1989-07-26
FI885056A (fi) 1989-05-05
DK614088D0 (da) 1988-11-03
JPH01151555A (ja) 1989-06-14
CN1040192A (zh) 1990-03-07
NO884671L (no) 1989-05-05
HUT48591A (en) 1989-06-28
AU613101B2 (en) 1991-07-25
US5008279A (en) 1991-04-16
EP0315018A3 (de) 1990-07-18

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