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NO884324L - PROCEDURE FOR THE PREPARATION OF PURE INHIBITIVE DIPEPTIDES AND THEIR USE. - Google Patents

PROCEDURE FOR THE PREPARATION OF PURE INHIBITIVE DIPEPTIDES AND THEIR USE.

Info

Publication number
NO884324L
NO884324L NO88884324A NO884324A NO884324L NO 884324 L NO884324 L NO 884324L NO 88884324 A NO88884324 A NO 88884324A NO 884324 A NO884324 A NO 884324A NO 884324 L NO884324 L NO 884324L
Authority
NO
Norway
Prior art keywords
inhibitive
dipeptides
pure
procedure
preparation
Prior art date
Application number
NO88884324A
Other languages
Norwegian (no)
Other versions
NO884324D0 (en
Inventor
Adalbert Wagner
Heinz-Werner Kleemann
Dieter Ruppert
Bernward Schoelkens
Hansjoerg Urbach
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO884324D0 publication Critical patent/NO884324D0/en
Publication of NO884324L publication Critical patent/NO884324L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO88884324A 1987-09-30 1988-09-29 PROCEDURE FOR THE PREPARATION OF PURE INHIBITIVE DIPEPTIDES AND THEIR USE. NO884324L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19873732971 DE3732971A1 (en) 1987-09-30 1987-09-30 RENINE INHIBITING DIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THE AGENTS CONTAINING THEM AND THEIR USE

Publications (2)

Publication Number Publication Date
NO884324D0 NO884324D0 (en) 1988-09-29
NO884324L true NO884324L (en) 1989-03-31

Family

ID=6337246

Family Applications (1)

Application Number Title Priority Date Filing Date
NO88884324A NO884324L (en) 1987-09-30 1988-09-29 PROCEDURE FOR THE PREPARATION OF PURE INHIBITIVE DIPEPTIDES AND THEIR USE.

Country Status (13)

Country Link
EP (1) EP0310015A3 (en)
JP (1) JPH01121258A (en)
KR (1) KR890005146A (en)
AU (1) AU624579B2 (en)
DE (1) DE3732971A1 (en)
DK (1) DK543788A (en)
FI (1) FI884455A (en)
HU (1) HU203118B (en)
IL (1) IL87912A0 (en)
NO (1) NO884324L (en)
NZ (1) NZ226361A (en)
PT (1) PT88622B (en)
ZA (1) ZA887264B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL87614A0 (en) * 1987-09-16 1989-01-31 Abbott Lab Peptidylheterocycles
DE3804793A1 (en) * 1988-02-16 1989-08-24 Hoechst Ag RENIN-INHIBITING AMINOSAUTE DERIVATIVES
DE3814325A1 (en) * 1988-04-28 1989-11-09 Merck Patent Gmbh AMINOSAEUREDERIVATE
DE3841520A1 (en) * 1988-12-09 1990-06-13 Hoechst Ag ENZYME-INFRINGING DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, METHODS CONTAINING THEM AND THEIR USE
DE3913290A1 (en) * 1989-04-22 1990-10-25 Hoechst Ag RENIN-INHIBITING DI- AND TRIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THE MEANS CONTAINING THEM AND THEIR USE
TW225540B (en) * 1990-06-28 1994-06-21 Shionogi & Co
US5554641A (en) * 1995-03-20 1996-09-10 Horwell; David C. Nonpeptides as tachykinin antagonists
JP4696352B2 (en) * 2000-11-30 2011-06-08 トヨタ自動車株式会社 Vehicle power supply

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3538749A1 (en) * 1985-10-31 1987-05-07 Merck Patent Gmbh PEPTIDE
DE3601248A1 (en) * 1986-01-17 1987-07-23 Hoechst Ag SUBSTITUTED 4-AMINO-3-HYDROXYBUTTERIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE
ZA87563B (en) * 1986-02-03 1987-09-30 Squibb & Sons Inc N-heterocyclic alcohol renin inhibitors
DE3627877A1 (en) * 1986-07-30 1988-02-04 Hoechst Ag RENINE-INHIBITING DI- AND TRIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE
HU204285B (en) * 1986-10-31 1991-12-30 Pfizer Process for producing renin-inhibiting polypeptides of small molecule mass and pharmaceutical compositions containing them
GB2200115B (en) * 1987-01-21 1990-11-14 Sandoz Ltd Novel peptide derivatives, their production and use

Also Published As

Publication number Publication date
AU624579B2 (en) 1992-06-18
HUT48278A (en) 1989-05-29
EP0310015A2 (en) 1989-04-05
PT88622A (en) 1989-07-31
FI884455A0 (en) 1988-09-28
AU2295988A (en) 1989-06-29
NZ226361A (en) 1991-12-23
HU203118B (en) 1991-05-28
NO884324D0 (en) 1988-09-29
PT88622B (en) 1993-07-30
FI884455A (en) 1989-03-31
EP0310015A3 (en) 1992-05-20
DE3732971A1 (en) 1989-04-20
DK543788A (en) 1989-03-31
IL87912A0 (en) 1989-03-31
KR890005146A (en) 1989-05-13
JPH01121258A (en) 1989-05-12
DK543788D0 (en) 1988-09-29
ZA887264B (en) 1989-06-28

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