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NO822592L - PROCEDURE FOR THE PREPARATION OF CAPSULAR BACTERY POLYOSIDES - Google Patents

PROCEDURE FOR THE PREPARATION OF CAPSULAR BACTERY POLYOSIDES

Info

Publication number
NO822592L
NO822592L NO822592A NO822592A NO822592L NO 822592 L NO822592 L NO 822592L NO 822592 A NO822592 A NO 822592A NO 822592 A NO822592 A NO 822592A NO 822592 L NO822592 L NO 822592L
Authority
NO
Norway
Prior art keywords
capsular
polyosides
bacteriae
give
retained material
Prior art date
Application number
NO822592A
Other languages
Norwegian (no)
Other versions
NO159394C (en
NO159394B (en
Inventor
Demetre Yavordios
Mireille Cousin
Original Assignee
Berri Balzac
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berri Balzac filed Critical Berri Balzac
Publication of NO822592L publication Critical patent/NO822592L/en
Publication of NO159394B publication Critical patent/NO159394B/en
Publication of NO159394C publication Critical patent/NO159394C/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0266Klebsiella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/09Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A61K39/092Streptococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Polyesters Or Polycarbonates (AREA)

Abstract

1. Claims (for the Contracting States : BE, CH, DE, FR, GB, IT, LI, LU, NL, SE) Process for the production of immunogenic capsular polyosides from capsulated bacteriae containing same, characterised in that it consists in cultivating the bacteriae in a synthetic medium which may contain up to about 0.5% by weight of naturally occuring materials ; at the end of the growth stage of said culture removing the microbial bodies, submitting the liquid phase after removal of the microbial bodies to a filtration through a membrane which retains the molecules of a molecular weight of 100 000 daltons or more, to give a capsular polyosides-rich retained material ; and removing the proteins, the nucleic acids and the lipids from said retained material, to give a purified capsular polyoside. 1. Claims (for the Contracting State AT) Process for the production of immunogenic capsular polyosides from capsulated bacteriae containing same, characterised in that it consists in cultivating the bacteriae in a synthetic medium which may contain up to about 0.5% by weight of naturally occuring materials ; at the end of the growth stage of said culture removing the microbial bodies, submitting the liquid phase after removal of the microbial bodies to a filtration through a membrane which retains the molecules of a molecular weight of 100 000 daltons or more, to give a capsular polyosides-rich retained material ; and removing the proteins, the nucleic acids and the lipids from said retained material, to give a purified capsular polyoside.
NO822592A 1981-07-30 1982-07-28 PROCEDURE FOR THE PREPARATION OF IMMUNOGENIC CAPSULATED POLYOSIDES FROM Capsule Bacteria. NO159394C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8114842A FR2510606A1 (en) 1981-07-30 1981-07-30 PROCESS FOR OBTAINING CAPSULAR POLYOSIDES, CAPSULAR POLYOSIDES THUS OBTAINED AND THEIR APPLICATION TO THE PREPARATION OF VACCINES

Publications (3)

Publication Number Publication Date
NO822592L true NO822592L (en) 1983-01-31
NO159394B NO159394B (en) 1988-09-12
NO159394C NO159394C (en) 1988-12-21

Family

ID=9261011

Family Applications (1)

Application Number Title Priority Date Filing Date
NO822592A NO159394C (en) 1981-07-30 1982-07-28 PROCEDURE FOR THE PREPARATION OF IMMUNOGENIC CAPSULATED POLYOSIDES FROM Capsule Bacteria.

Country Status (11)

Country Link
EP (1) EP0071515B1 (en)
AT (1) ATE16244T1 (en)
CA (1) CA1206905A (en)
DD (1) DD202623A5 (en)
DE (1) DE3267160D1 (en)
DK (1) DK327182A (en)
ES (1) ES514496A0 (en)
FR (1) FR2510606A1 (en)
IE (1) IE53582B1 (en)
NO (1) NO159394C (en)
PT (1) PT75301B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0238739B1 (en) * 1986-03-27 1992-02-05 Swiss Serum and Vaccine Institute Berne Klebsiella capsular polysaccharide vaccine
US6426074B1 (en) * 1997-03-19 2002-07-30 The Brigham And Women's Hospital Inc. Group B Streptococcus vaccine
DK1268844T3 (en) * 2000-03-16 2009-11-16 Philadelphia Children Hospital Modulation of preparation of pneumococcus capsular polysaccharide
NZ511680A (en) 2001-05-14 2004-07-30 Univ Waikato Method for preparing nucleic acid or DNA samples and a DNA extraction process using thermophilic proteases
GB0522303D0 (en) * 2005-11-01 2005-12-07 Chiron Srl Culture method
EP2155244B1 (en) 2007-04-23 2017-03-22 Serum Institute of India Private Limited Antigenic polysaccharides and process for their preparation
WO2011148382A1 (en) 2010-05-28 2011-12-01 Biological E Limited An improved process for the purification of capsular polysaccharides of haemophilus influenza - b, neisseria meningitis such as serotypes a, c, y and w-135, and other similar related capsular polysaccharides produced from both gram negative and gram positive microorganisms using aluminium phosphate with alcohol.
WO2011151841A1 (en) * 2010-05-31 2011-12-08 Panacea Biotec Limited Fermentation process for streptococcus pneumoniae
BR112019013475A2 (en) 2016-12-30 2020-02-27 Sutrovax, Inc. POLYPEPTIDE-ANTIGEN CONJUGATES WITH NON-NATURAL AMINO ACIDS
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
WO2020010016A1 (en) 2018-07-04 2020-01-09 Sutrovax, Inc. Self-adjuvanted immunogenic conjugates
WO2024062494A1 (en) 2022-09-19 2024-03-28 Biological E Limited Method for the purification of capsular polysaccharides

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2166963A (en) * 1936-11-19 1939-07-25 Sharp & Dohme Inc Antigenic polysaccharide complex
US2528972A (en) * 1947-05-15 1950-11-07 Western Reserve University Prophylactic toxoid compound and method of making same
FR2407262A1 (en) * 1977-10-27 1979-05-25 Cassenne Lab Sa NEW POLYSACCHARIDES MICROBIAL BODY EXTRACTS OF HAEMOPHILUS INFLUENZAE, PROCESS FOR THE PREPARATION AND APPLICATION AS MEDICINAL PRODUCTS OF THESE NEW PRODUCTS
CA1115210A (en) * 1977-11-28 1981-12-29 Dennis J. Carlo Pneumococcal vaccine
US4264764A (en) * 1979-01-12 1981-04-28 Merck & Co., Inc. Meningitis vaccine
US4221906A (en) * 1979-03-19 1980-09-09 American Cyanamid Company Stabilization of pneumococcal polysaccharides
US4307080A (en) * 1979-09-24 1981-12-22 Merck & Co., Inc. Meningitis vaccine
US4287173A (en) * 1979-09-24 1981-09-01 Merck & Co., Inc. Vaccine for dental caries

Also Published As

Publication number Publication date
EP0071515B1 (en) 1985-10-30
DD202623A5 (en) 1983-09-28
IE821705L (en) 1983-01-30
DK327182A (en) 1983-01-31
PT75301B (en) 1984-07-31
PT75301A (en) 1982-08-01
ATE16244T1 (en) 1985-11-15
EP0071515A1 (en) 1983-02-09
NO159394C (en) 1988-12-21
ES8305827A1 (en) 1983-04-16
CA1206905A (en) 1986-07-02
IE53582B1 (en) 1988-12-21
DE3267160D1 (en) 1985-12-05
FR2510606B1 (en) 1984-10-26
FR2510606A1 (en) 1983-02-04
NO159394B (en) 1988-09-12
ES514496A0 (en) 1983-04-16

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