NO792993L - Fremgangsmaate ved fremstilling av fenylalkylaminoethylsalicylamider - Google Patents

Fremgangsmaate ved fremstilling av fenylalkylaminoethylsalicylamider

Info

Publication number: NO792993L
Authority: NO; Norway
Prior art keywords: acid addition; optical isomer; labetalol; protected; pharmaceutically acceptable
Prior art date: 1978-09-20

Application number

NO792993A

Other languages

English (en)

Other versions

NO149660C (no

NO149660B (no

Inventor

Gold Elijah Herman

Chang Wei

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-09-20

Filing date

1979-09-17

Publication date

1980-03-21

1979-09-17 Application filed by Schering Corp filed Critical Schering Corp

1980-03-21 Publication of NO792993L publication Critical patent/NO792993L/no

1984-02-20 Publication of NO149660B publication Critical patent/NO149660B/no

1984-05-30 Publication of NO149660C publication Critical patent/NO149660C/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/65—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Ophthalmology & Optometry (AREA)
Vascular Medicine (AREA)
Rheumatology (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Epoxy Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

NO792993A 1978-09-20 1979-09-17 Analogifremgangsmaate for fremstilling av terapeutisk aktiv (r,r) optisk isomer av labetalol NO149660C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US94451678A	1978-09-20	1978-09-20

Publications (3)

Publication Number	Publication Date
NO792993L true NO792993L (no)	1980-03-21
NO149660B NO149660B (no)	1984-02-20
NO149660C NO149660C (no)	1984-05-30

Family

ID=25481553

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO792993A NO149660C (no)	1978-09-20	1979-09-17	Analogifremgangsmaate for fremstilling av terapeutisk aktiv (r,r) optisk isomer av labetalol

Country Status (27)

Country	Link
EP (1)	EP0009702B1 (no)
JP (3)	JPS5555147A (no)
KR (2)	KR830000904A (no)
AT (1)	ATE351T1 (no)
AU (1)	AU528626B2 (no)
CA (1)	CA1151211A (no)
CY (1)	CY1175A (no)
DD (1)	DD150457A5 (no)
DE (1)	DE2961263D1 (no)
DK (1)	DK387579A (no)
FI (1)	FI792884A (no)
GR (1)	GR73179B (no)
HK (1)	HK13383A (no)
HU (1)	HU185523B (no)
IE (1)	IE49301B1 (no)
IL (1)	IL58258A (no)
KE (1)	KE3283A (no)
MY (1)	MY8500042A (no)
NO (1)	NO149660C (no)
NZ (1)	NZ191589A (no)
OA (1)	OA06339A (no)
PH (1)	PH16794A (no)
PL (1)	PL129114B1 (no)
PT (1)	PT70191A (no)
SG (1)	SG283G (no)
YU (1)	YU227379A (no)
ZA (1)	ZA794872B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4658060A (en) *	1982-04-26	1987-04-14	Schering Corporation	Preparation of (-)-5-(beta)-1-hydroxy-2-((beta)-1-methyl-3-phenylpropyl)aminoethyl) salicylamide
IT1194406B (it) *	1983-09-27	1988-09-22	Scharper S P A	Procedimento per la preparazione di 2-idrossi-5-01-idrossi-2-((4-fenil-2-butil)ammino) etil benzammide
HU190867B (en) *	1984-01-20	1986-11-28	Egyt Gyogyszervegyeszeti Gyar,Hu	Process for preparing 2-hydroxy-5-/1-hydroxy-2-/1-methyl-3-phenyl-propyl/-amino/ethyl/-benzamide and pharmaceutically acceptable salts thereof
US4788183A (en) *	1987-11-30	1988-11-29	Schering Corporation	Method for treatment of dyslipidemia in humans
US4879233A (en) *	1989-02-10	1989-11-07	Schering Corporation	Novel Aspergillus niveus microorganism used for the chiral reduction of carbonyl groups
US6011068A (en) *	1991-08-23	2000-01-04	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
US5858684A (en) *	1991-08-23	1999-01-12	The Brigham And Women's Hospital, Inc.	Method of screening calcium receptor-active molecules
EP1281702B1 (en) *	1991-08-23	2005-12-21	Nps Pharmaceuticals, Inc.	Calcium receptor active molecules
US5763569A (en) *	1991-08-23	1998-06-09	The Brigham And Women's Hospital, Inc	Calcium receptor-active molecules
US6001884A (en) *	1991-08-23	1999-12-14	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
US6031003A (en) *	1991-08-23	2000-02-29	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
US5688938A (en) *	1991-08-23	1997-11-18	The Brigham & Women's Hospital, Inc.	Calcium receptor-active molecules
US6313146B1 (en)	1991-08-23	2001-11-06	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
US5962314A (en) *	1993-02-23	1999-10-05	Nps Pharmaceuticals, Inc.	Calcium receptor-active molecules
CN1312116C (zh)	1994-10-21	2007-04-25	Nps药物有限公司	钙受体活性化合物
DE69739388D1 (de)	1996-05-01	2009-06-10	Nps Pharma Inc	Inorganische am Ionen-Rezeptor aktive Verbindungen
IT1313583B1 (it)	1999-07-30	2002-09-09	Chiesi Farma Spa	Derivati 2-amminotetralinici per la terapia del glaucoma.
ES2333266T3 (es) *	2007-02-22	2010-02-18	Indena S.P.A.	Procedimiento para la preparacion de sal de acetato del ester metilico de (2r,3s)-3-fenilisoserina.
EP2603215A4 (en)	2010-08-11	2015-08-05	Philadelphia Health & Educatio	NEW DOPAMINERGIC D3 RECEPTOR AGONISTS FOR TREATING DYSKINESIA IN PARKINSON'S DISEASE

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1266058A (no) *	1969-07-08	1972-03-08
US4012444A (en) *	1969-07-08	1977-03-15	Allen & Hanburys Limited	5-[1-Hydroxy-2-(1-methyl-3-phenylpropyl)aminoethyl] salicylamide and physiologically acceptable acid addition salts thereof
GB1541932A (en) *	1975-04-17	1979-03-14	Scherico Ltd	Diastereoisomers of a phenylalkylaminoethanol derivative

1979
- 1979-09-13 ZA ZA00794872A patent/ZA794872B/xx unknown
- 1979-09-17 PH PH23042A patent/PH16794A/en unknown
- 1979-09-17 NZ NZ191589A patent/NZ191589A/en unknown
- 1979-09-17 AT AT79103473T patent/ATE351T1/de not_active IP Right Cessation
- 1979-09-17 FI FI792884A patent/FI792884A/fi not_active Application Discontinuation
- 1979-09-17 NO NO792993A patent/NO149660C/no unknown
- 1979-09-17 CY CY1175A patent/CY1175A/xx unknown
- 1979-09-17 EP EP79103473A patent/EP0009702B1/en not_active Expired
- 1979-09-17 AU AU50881/79A patent/AU528626B2/en not_active Ceased
- 1979-09-17 DE DE7979103473T patent/DE2961263D1/de not_active Expired
- 1979-09-17 DK DK387579A patent/DK387579A/da not_active Application Discontinuation
- 1979-09-18 IE IE1770/79A patent/IE49301B1/en unknown
- 1979-09-18 YU YU02273/79A patent/YU227379A/xx unknown
- 1979-09-18 IL IL58258A patent/IL58258A/xx unknown
- 1979-09-18 GR GR60059A patent/GR73179B/el unknown
- 1979-09-18 OA OA56898A patent/OA06339A/xx unknown
- 1979-09-18 PT PT70191A patent/PT70191A/pt unknown
- 1979-09-18 JP JP11996879A patent/JPS5555147A/ja active Granted
- 1979-09-18 CA CA000335885A patent/CA1151211A/en not_active Expired
- 1979-09-18 KR KR1019790003218A patent/KR830000904A/ko unknown
- 1979-09-19 PL PL1979218408A patent/PL129114B1/pl unknown
- 1979-09-19 DD DD79215640A patent/DD150457A5/de unknown
- 1979-09-19 HU HU79SCHE690A patent/HU185523B/hu unknown
1983
- 1983-01-04 SG SG2/83A patent/SG283G/en unknown
- 1983-04-21 HK HK133/83A patent/HK13383A/xx unknown
- 1983-04-25 KE KE3283A patent/KE3283A/xx unknown
- 1983-11-17 JP JP58217073A patent/JPS59108749A/ja active Pending
1984
- 1984-04-09 KR KR1019840001867A patent/KR890001998B1/ko not_active IP Right Cessation
1985
- 1985-12-30 MY MY42/85A patent/MY8500042A/xx unknown
1989
- 1989-11-13 JP JP1292552A patent/JPH02167253A/ja active Pending

Also Published As

Publication number	Publication date
NO149660C (no)	1984-05-30
FI792884A (fi)	1980-03-21
EP0009702B1 (en)	1981-11-04
KE3283A (en)	1983-05-13
DD150457A5 (de)	1981-09-02
HK13383A (en)	1983-04-29
IL58258A0 (en)	1979-12-30
DK387579A (da)	1980-03-21
CA1151211A (en)	1983-08-02
JPS5555147A (en)	1980-04-22
IL58258A (en)	1984-01-31
OA06339A (fr)	1981-06-30
YU227379A (en)	1983-06-30
EP0009702A1 (en)	1980-04-16
NZ191589A (en)	1984-03-30
AU5088179A (en)	1980-03-27
KR890001998B1 (ko)	1989-06-07
CY1175A (en)	1983-06-10
MY8500042A (en)	1985-12-31
ATE351T1 (de)	1981-11-15
HU185523B (en)	1985-02-28
SG283G (en)	1983-09-16
GR73179B (no)	1984-02-14
PL129114B1 (en)	1984-03-31
JPS59108749A (ja)	1984-06-23
JPH0210128B2 (no)	1990-03-06
PL218408A1 (no)	1980-09-08
NO149660B (no)	1984-02-20
PH16794A (en)	1984-02-28
KR840005307A (ko)	1984-11-05
DE2961263D1 (en)	1982-01-14
JPH02167253A (ja)	1990-06-27
AU528626B2 (en)	1983-05-05
ZA794872B (en)	1980-11-26
IE49301B1 (en)	1985-09-18
KR830000904A (ko)	1983-04-28
PT70191A (en)	1979-10-01
IE791770L (en)	1980-03-20

Publication	Publication Date	Title
NO792993L (no)	1980-03-21	Fremgangsmaate ved fremstilling av fenylalkylaminoethylsalicylamider
AU683442B2 (en)	1997-11-13	Aminoacid derivates, medicaments containing these compounds and process for preparing the same
PT92935A (pt)	1990-07-31	Processo para a preparacao de um composto de pirazolo-piridina e de composicoes farmaceuticas que o contem
CA2069901A1 (en)	1991-05-31	Pyrazolines for protecting crop plants against herbicides
CA2029787A1 (en)	1991-05-15	Method for preparation of taxol using an oxazinone
GB1459571A (en)	1976-12-22	Thiophene-2-sulphonamide derivatives and their use as therapeutic agents sheet orienting apparatus
PT90022A (pt)	1989-11-10	Processo para a preparacao de derivados cefem e dos intermediarios correspondentes
FI911131A0 (fi)	1991-03-06	Menetelmä viherkaihia estävien 3-aryylikarbonyyli-1-aminoalkyyli-1H-indoliyhdisteiden valmistamiseksi
DK562488A (da)	1989-04-09	Farmaceutisk praeparat indeholdende polyminderivater, samt nogle af disse polyaminderivater
FR2409755A1 (fr)	1979-06-22	Medicaments a base de nouvelles indolo (2,3-a) quinolizidines
WO1990003172A3 (en)	1990-06-28	Bile acids for treatment of viral infections
IE46171L (en)	1978-01-19	N-pyrrolidinylmethylbenzamide derivative.
ES524375A0 (es)	1984-12-16	Un procedimiento para preparar un compuesto de nitrato piridilalquilico
IL69448A (en)	1986-09-30	Process for combating phytopathogenic fungi with azolylphenoxy-tetrahydrofuran-2-ylidene methane derivatives
ES8403135A1 (es)	1984-03-01	Un procedimiento para la preparacion de acido 6,-metoxi-6, -2-2-metilfenoxicarbonil-2-(tien-3-il) acetamido penicilanico.
ES440767A2 (es)	1977-04-01	Procedimiento para la preparacion de derivados de fenileti- lamina.
ES8105719A1 (es)	1981-06-16	Procedimiento de obtencion de nuevas piperacinas 1,4-lisus- tituidas asimetricas y sus sales farmaceuticamente acepta- bles
JPS5540601A (en)	1980-03-22	New 3-(3,4-dihydroxyphenyl)serine derivative
JPS5598158A (en)	1980-07-25	Novel alpha-methyl-3,4-dihydroxyphenylalanine derivative and its preparation
JPS5371083A (en)	1978-06-24	Optical active homophthalimide derivs. and process for their preparing them
GB2316406A (en)	1998-02-25	Free radical scavenger molecules
ES476078A1 (es)	1979-05-16	Un procedimiento para preparar derivados del acido 1,3-tia- zol-glioxilico.
JPS5371084A (en)	1978-06-24	Optical active hydroxyisocarbostyryls and process for their preparation