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NO783360L - NEW PIPERAZINOPYRROLOBENZODIAZEPINES, PROCEDURES FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS, AND THEIR THERAPEUTIC USE - Google Patents

NEW PIPERAZINOPYRROLOBENZODIAZEPINES, PROCEDURES FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS, AND THEIR THERAPEUTIC USE

Info

Publication number
NO783360L
NO783360L NO783360A NO783360A NO783360L NO 783360 L NO783360 L NO 783360L NO 783360 A NO783360 A NO 783360A NO 783360 A NO783360 A NO 783360A NO 783360 L NO783360 L NO 783360L
Authority
NO
Norway
Prior art keywords
piperazinopyrrolobenzodiazepines
procedures
compounds
preparation
new
Prior art date
Application number
NO783360A
Other languages
Norwegian (no)
Other versions
NO150159B (en
NO150159C (en
Inventor
Jan W F Wasley
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO783360L publication Critical patent/NO783360L/en
Publication of NO150159B publication Critical patent/NO150159B/en
Publication of NO150159C publication Critical patent/NO150159C/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO783360A 1977-10-05 1978-10-04 ANALOGY PROCEDURE FOR THE PREPARATION OF NEW PHARMACOLOGICAL ACTIVITIES 1,3,4,14B-TETRAHYDRO-2H, 10H-PYRAZINO (1,2A) -PYRROLO (2,1-C) (1,4) BENZODIAZEPINE NO150159C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83969677A 1977-10-05 1977-10-05

Publications (3)

Publication Number Publication Date
NO783360L true NO783360L (en) 1979-04-06
NO150159B NO150159B (en) 1984-05-21
NO150159C NO150159C (en) 1984-08-29

Family

ID=25280422

Family Applications (1)

Application Number Title Priority Date Filing Date
NO783360A NO150159C (en) 1977-10-05 1978-10-04 ANALOGY PROCEDURE FOR THE PREPARATION OF NEW PHARMACOLOGICAL ACTIVITIES 1,3,4,14B-TETRAHYDRO-2H, 10H-PYRAZINO (1,2A) -PYRROLO (2,1-C) (1,4) BENZODIAZEPINE

Country Status (18)

Country Link
EP (1) EP0001585B1 (en)
JP (1) JPS5461199A (en)
AT (1) AT368157B (en)
AU (1) AU521335B2 (en)
CA (1) CA1113934A (en)
DD (1) DD138774A5 (en)
DE (1) DE2860861D1 (en)
DK (1) DK441278A (en)
ES (1) ES473900A1 (en)
FI (1) FI63578C (en)
HK (1) HK2185A (en)
HU (1) HU179948B (en)
IE (1) IE47390B1 (en)
IL (1) IL55664A (en)
NO (1) NO150159C (en)
NZ (1) NZ188580A (en)
SG (1) SG38684G (en)
ZA (2) ZA784475B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4737496A (en) * 1986-10-01 1988-04-12 Ciba-Geigy Corporation 1,3,4,16b-tetrahydro-2H,10H-indolo[2,1-c]pyrazino-[1,2-a][1,4]benzodiazepines useful as serotonin-2 receptor antagonists
CA2026925A1 (en) * 1989-10-05 1991-04-06 Hiroshi Fukumi Tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use
EP0539164A1 (en) * 1991-10-23 1993-04-28 Sankyo Company Limited Nitrogen-containing tetracyclic compounds having anti-allergic and anti-asthmatic activities, their preparation and use
AUPP433398A0 (en) * 1998-06-25 1998-07-16 Australian National University, The Compounds and processes

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3763183A (en) * 1972-07-10 1973-10-02 Sterling Drug Inc 1,2,3,10,11,11a-hexahydro-5h-pyrrolo (2,1-c)(1,4)benzodiazepines
US3985732A (en) * 1974-04-26 1976-10-12 American Cyanamid Company 1,2,3,11A-Tetrahydro-10-methyl-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5,11(10H)-diones
US3984562A (en) * 1975-02-24 1976-10-05 American Cyanamid Company Substituted benzodiazepines and method of use
US4017492A (en) * 1976-04-02 1977-04-12 The Upjohn Company As-triazinobenzodiazepin-1-ones
US4073784A (en) * 1977-03-09 1978-02-14 The Upjohn Company Certain as-triazino 4,3-a! 1,4!benzodiazepine-1,2-dione compounds

Also Published As

Publication number Publication date
SG38684G (en) 1985-03-29
EP0001585A1 (en) 1979-05-02
ATA715178A (en) 1982-01-15
ZA785599B (en) 1979-09-26
EP0001585B1 (en) 1981-07-22
FI63578B (en) 1983-03-31
AU4040178A (en) 1980-04-17
NO150159B (en) 1984-05-21
FI63578C (en) 1983-07-11
IE47390B1 (en) 1984-03-07
JPS5461199A (en) 1979-05-17
DK441278A (en) 1979-04-06
HK2185A (en) 1985-01-18
DD138774A5 (en) 1979-11-21
AU521335B2 (en) 1982-03-25
IL55664A0 (en) 1978-12-17
IE781985L (en) 1979-04-05
HU179948B (en) 1983-01-28
FI782994A (en) 1979-04-06
NO150159C (en) 1984-08-29
AT368157B (en) 1982-09-27
DE2860861D1 (en) 1981-10-29
NZ188580A (en) 1981-12-15
IL55664A (en) 1982-02-28
CA1113934A (en) 1981-12-08
ES473900A1 (en) 1979-04-16
ZA784475B (en) 1979-07-25

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